Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Tick Bites D064927 1 associated lipids
Chlamydial Pneumonia D061387 2 associated lipids
Reproductive Tract Infections D060737 1 associated lipids
Granulomatous Mastitis D058890 1 associated lipids
Trichiasis D058457 1 associated lipids
Asymptomatic Infections D058345 1 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Neglected Diseases D058069 3 associated lipids
Corneal Endothelial Cell Loss D055954 1 associated lipids
Multiple Pulmonary Nodules D055613 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

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Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Rodriguez AF An open study to compare azithromycin with cefaclor in the treatment of children with acute otitis media. 1996 J. Antimicrob. Chemother. pmid:8818847
O'Doherty B An open comparative study of azithromycin versus cefaclor in the treatment of patients with upper respiratory tract infections. 1996 J. Antimicrob. Chemother. pmid:8818848
Müller O An open comparative study of azithromycin and roxithromycin in the treatment of acute upper respiratory tract infections. 1996 J. Antimicrob. Chemother. pmid:8818849
Gris P Once-daily, 3-day azithromycin versus a three-times-daily, 10-day course of co-amoxiclav in the treatment of adults with lower respiratory tract infections: results of a randomized, double-blind comparative study. 1996 J. Antimicrob. Chemother. pmid:8818850
Zachariah J A randomized, comparative study to evaluate the efficacy and tolerability of a 3-day course of azithromycin versus a 10-day course of co-amoxiclav as treatment of adult patients with lower respiratory tract infections. 1996 J. Antimicrob. Chemother. pmid:8818851
Laurent K Efficacy, safety and tolerability of azithromycin versus roxithromycin in the treatment of acute lower respiratory tract infections. 1996 J. Antimicrob. Chemother. pmid:8818852
Montero L A comparative study of the efficacy, safety and tolerability of azithromycin and cefaclor in the treatment of children with acute skin and/or soft tissue infections. 1996 J. Antimicrob. Chemother. pmid:8818853
Nahata M Drug interactions with azithromycin and the macrolides: an overview. 1996 J. Antimicrob. Chemother. pmid:8818854
Treadway G and Pontani D Paediatric safety of azithromycin: worldwide experience. 1996 J. Antimicrob. Chemother. pmid:8818855
Carbon C et al. Economic analysis of antibiotic regimens used in the treatment pharyngitis: a prospective comparison of azithromycin versus roxithromycin. 1996 J. Antimicrob. Chemother. pmid:8818856
Silvestri M et al. Azithromycin induces in vitro a time-dependent increase in the intracellular killing of Staphylococcus aureus by human polymorphonuclear leucocytes without damaging phagocytes. 1995 J. Antimicrob. Chemother. pmid:8821593
Patton DL et al. The activity of azithromycin on the infectivity of Chlamydia trachomatis in human amniotic cells. 1995 J. Antimicrob. Chemother. pmid:8821594
Lane G Increased hypoprothrombinemic effect of warfarin possibly induced by azithromycin. 1996 Jul-Aug Ann Pharmacother pmid:8826581
Gerbaux C et al. Hyperactivity of cathepsin B and other lysosomal enzymes in fibroblasts exposed to azithromycin, a dicationic macrolide antibiotic with exceptional tissue accumulation. 1996 FEBS Lett. pmid:8830663
Domingo S and Gamazo C Inadequate azithromycin activity against Brucella melitensis in mice with acute or chronic infections. 1996 J Chemother pmid:8835110
Ehret JM et al. A clinical isolate of Neisseria gonorrhoeae with in vitro resistance to erythromycin and decreased susceptibility to azithromycin. 1996 Jul-Aug Sex Transm Dis pmid:8836018
Gnarpe J et al. In vitro activities of azithromycin and doxycycline against 15 isolates of Chlamydia pneumoniae. 1996 Antimicrob. Agents Chemother. pmid:8843291
Ednie LM et al. Comparative activities of clarithromycin, erythromycin, and azithromycin against penicillin-susceptible and penicillin-resistant pneumococci. 1996 Antimicrob. Agents Chemother. pmid:8843313
Bessette RE and Amsden GW Treatment of non-HIV cryptosporidial diarrhea with azithromycin. 1995 Ann Pharmacother pmid:8845560
Lo KK et al. An open non-comparative pilot study with azithromycin in the treatment of non-gonococcal urethritis in the sexually transmitted disease clinics in Hong Kong. 1995 Ann. Acad. Med. Singap. pmid:8849186
Pacifico L et al. Comparative efficacy and safety of 3-day azithromycin and 10-day penicillin V treatment of group A beta-hemolytic streptococcal pharyngitis in children. 1996 Antimicrob. Agents Chemother. pmid:8849215
Wondrack L et al. Clinical strain of Staphylococcus aureus inactivates and causes efflux of macrolides. 1996 Antimicrob. Agents Chemother. pmid:8849266
Amsden GW Erythromycin, clarithromycin, and azithromycin: are the differences real? 1996 Jan-Feb Clin Ther pmid:8851453
Jaruratanasirikul S et al. Distribution of azithromycin into brain tissue, cerebrospinal fluid, and aqueous humor of the eye. 1996 Antimicrob. Agents Chemother. pmid:8851625
Preac Mursic V et al. Kill kinetics of Borrelia burgdorferi and bacterial findings in relation to the treatment of Lyme borreliosis. 1996 Jan-Feb Infection pmid:8852456
Baradaran-Dilmaghani R and Stanek G In vitro susceptibility of thirty Borrelia strains from various sources against eight antimicrobial chemotherapeutics. 1996 Jan-Feb Infection pmid:8852472
Strle F et al. Azithromycin and doxycycline for treatment of Borrelia culture-positive erythema migrans. 1996 Jan-Feb Infection pmid:8852473
Gómez E et al. Interaction between azithromycin and cyclosporin? 1996 Nephron pmid:8856287
Burke SM Azithromycin: only once a day. 1996 May-Jun MCN Am J Matern Child Nurs pmid:8857402
Delmée M et al. In vitro susceptibilities of 180 clinical isolates of Haemophilus influenzae to ampicillin, amoxycillin/clavulanate, cefaclor, cefuroxime, cefotaxime, clarithromycin, and azithromycin. 1996 Acta Clin Belg pmid:8858889
Xu G et al. Effect of macrolide antibiotics on macrophage functions. 1996 Microbiol. Immunol. pmid:8865152
Vranes J et al. Influence of subinhibitory concentrations of ceftazidime, ciprofloxacin and azithromycin on the morphology and adherence of P-fimbriated escherichia coli. 1996 J Chemother pmid:8873829
Laing RB et al. Clinical features, outcome and survival from cerebral toxoplasmosis in Edinburgh AIDS patients. 1996 Int J STD AIDS pmid:8876356
Schaad UB and Heynen G Evaluation of the efficacy, safety and toleration of azithromycin vs. penicillin V in the treatment of acute streptococcal pharyngitis in children: results of a multicenter, open comparative study. The Swiss Tonsillopharyngitis Study Group. 1996 Pediatr. Infect. Dis. J. pmid:8878223
McLinn S and Williams D Incidence of antibiotic-resistant Streptococcus pneumoniae and beta-lactamase-positive Haemophilus influenzae in clinical isolates from patients with otitis media. 1996 Pediatr. Infect. Dis. J. pmid:8878239
McCarty J A multicenter, open label trial of azithromycin for the treatment of children with acute otitis media. 1996 Pediatr. Infect. Dis. J. pmid:8878240
Aronovitz G A multicenter, open label trial of azithromycin vs. amoxicillin/ clavulanate for the management of acute otitis media in children. 1996 Pediatr. Infect. Dis. J. pmid:8878241
McLinn S A multicenter, double blind comparison of azithromycin and amoxicillin/ clavulanate for the treatment of acute otitis media in children. 1996 Pediatr. Infect. Dis. J. pmid:8878242
Khurana CM A multicenter, randomized, open label comparison of azithromycin and amoxicillin/clavulanate in acute otitis media among children attending day care or school. 1996 Pediatr. Infect. Dis. J. pmid:8878243
Powers JL Properties of azithromycin that enhance the potential for compliance in children with upper respiratory tract infections. 1996 Pediatr. Infect. Dis. J. pmid:8878244
Wenisch C et al. Effect of single oral dose of azithromycin, clarithromycin, and roxithromycin on polymorphonuclear leukocyte function assessed ex vivo by flow cytometry. 1996 Antimicrob. Agents Chemother. pmid:8878577
Yeates RA et al. Interaction between midazolam and clarithromycin: comparison with azithromycin. 1996 Int J Clin Pharmacol Ther pmid:8880291
Dunn CJ and Barradell LB Azithromycin. A review of its pharmacological properties and use as 3-day therapy in respiratory tract infections. 1996 Drugs pmid:8882383
Watt B et al. Comparative activity of azithromycin against clinical isolates of mycobacteria. 1996 J. Antimicrob. Chemother. pmid:8889727
Tateda K et al. Direct evidence for antipseudomonal activity of macrolides: exposure-dependent bactericidal activity and inhibition of protein synthesis by erythromycin, clarithromycin, and azithromycin. 1996 Antimicrob. Agents Chemother. pmid:8891128
Patel KB et al. Comparison of bronchopulmonary pharmacokinetics of clarithromycin and azithromycin. 1996 Antimicrob. Agents Chemother. pmid:8891147
Hunt Gerardo S et al. Comparison of Etest to broth microdilution method for testing Streptococcus pneumoniae susceptibility to levofloxacin and three macrolides. 1996 Antimicrob. Agents Chemother. pmid:8891154
Wintermeyer SM et al. Dirithromycin: a new macrolide. 1996 Ann Pharmacother pmid:8893122
Biebuyck XA Comparison of azithromycin and co-amoxiclav in the treatment of acute tracheobronchitis and acute infectious exacerbations of chronic bronchitis in adults. Azithromycin Study Group. 1996 Sep-Oct J. Int. Med. Res. pmid:8895044
Three new studies expand understanding of MAC therapy. 1996 Am J Health Syst Pharm pmid:8899122