| MeSH term | MeSH ID | Detail |
|---|---|---|
| Tick Bites | D064927 | 1 associated lipids |
| Chlamydial Pneumonia | D061387 | 2 associated lipids |
| Reproductive Tract Infections | D060737 | 1 associated lipids |
| Granulomatous Mastitis | D058890 | 1 associated lipids |
| Trichiasis | D058457 | 1 associated lipids |
| Asymptomatic Infections | D058345 | 1 associated lipids |
| Acute Kidney Injury | D058186 | 34 associated lipids |
| Neglected Diseases | D058069 | 3 associated lipids |
| Corneal Endothelial Cell Loss | D055954 | 1 associated lipids |
| Multiple Pulmonary Nodules | D055613 | 2 associated lipids |
Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Caumes E et al. | [Donovanosis (granuloma inguinale)]. | 2016 | Ann Dermatol Venereol | pmid:27773509 |
| Abeles SR et al. | Microbial diversity in individuals and their household contacts following typical antibiotic courses. | 2016 | Microbiome | pmid:27473422 |
| Lockington D | Oral azithromycin and blepharitis: symptoms and signs improve, so where are the publications? | 2016 | Clin. Experiment. Ophthalmol. | pmid:27356302 |
| Guo Y et al. | Chlamydiaphage φCPG1 Capsid Protein Vp1 Inhibits Chlamydia trachomatis Growth via the Mitogen-Activated Protein Kinase Pathway. | 2016 | Viruses | pmid:27089359 |
| Hu J et al. | Streptococcus pneumoniae and Haemophilus influenzae type b carriage in Chinese children aged 12-18 months in Shanghai, China: a cross-sectional study. | 2016 | BMC Infect. Dis. | pmid:27080523 |
| McClure KS and Cameron ST | An audit of expedited treatment for uncomplicated Chlamydia trachomatis index cases at the community pharmacy. | 2016 | Int J STD AIDS | pmid:26945591 |
| Martin I et al. | Decline in Decreased Cephalosporin Susceptibility and Increase in Azithromycin Resistance in Neisseria gonorrhoeae, Canada. | 2016 | Emerging Infect. Dis. | pmid:26689114 |
| Chang Y et al. | Factors Influencing the HPLC Determination for Related Substances of Azithromycin. | 2016 | J Chromatogr Sci | pmid:26324196 |
| Caspi M et al. | A flow cytometry-based reporter assay identifies macrolide antibiotics as nonsense mutation read-through agents. | 2016 | J. Mol. Med. | pmid:26620677 |
| Gaudreau C et al. | Shigella flexneri with Ciprofloxacin Resistance and Reduced Azithromycin Susceptibility, Canada, 2015. | 2016 | Emerging Infect. Dis. | pmid:27767915 |
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| Das S and Mohanty M | Comparative evaluation of 2 g single dose versus conventional dose azithromycin in uncomplicated skin and skin structure infections. | 2016 Jan-Feb | Indian J Pharmacol | pmid:26997734 |
| Das A et al. | Azithromycin induced bullous fixed drug eruption. | 2016 Jan-Feb | Indian J Pharmacol | pmid:26997729 |
| Chatterjee S et al. | Azithromycin susceptibility among clinical isolates of Salmonella: Interfacing guidelines with routine practices. | 2016 Jul-Sep | Indian J Med Microbiol | pmid:27514976 |
| Latif SA et al. | Azithromycin buccal patch in treatment of chronic periodontitis. | 2016 Mar-Apr | Indian J Pharmacol | pmid:27127325 |
| Oliveira IS et al. | Evaluation of the improvement of quality of life with Azithromycin in the treatment of eosinophilic nasal polyposis. | 2016 Mar-Apr | Braz J Otorhinolaryngol | pmid:26601998 |
| Akoglu G et al. | Erlotinib-induced purpuric papulopustular eruption treated with pulsed azithromycin. | 2016 May-Jun | Indian J Pharmacol | pmid:27298507 |
| Diniz LM et al. | Bacillary angiomatosis with bone invasion. | 2016 Nov-Dec | An Bras Dermatol | pmid:28099606 |
| Paul P et al. | Capillary electrophoresis with capacitively coupled contactless conductivity detection method development and validation for the determination of azithromycin, clarithromycin, and clindamycin. | 2017 | J Sep Sci | pmid:28683179 |
| Volgers C et al. | Budesonide, fluticasone propionate, and azithromycin do not modulate the membrane vesicle release by THP-1 macrophages and respiratory pathogens during macrophage infection. | 2017 | Inflammopharmacology | pmid:28528362 |
| Stieger N et al. | Solution-mediated crystallization of amorphous azithromycin. | 2017 | Pharmazie | pmid:29441902 |
| Feng X and Liu J | A combination of irsogladine maleate and azithromycin exhibits addictive protective effects in LPS-induced human gingival epithelial cells. | 2017 | Pharmazie | pmid:29441859 |
| Jordan SJ et al. | Lower Levels of Cervicovaginal Tryptophan Are Associated With Natural Clearance of Chlamydia in Women. | 2017 | J. Infect. Dis. | pmid:28520912 |
| Lopes Dos Santos Santiago G et al. | Influence of chronic azithromycin treatment on the composition of the oropharyngeal microbial community in patients with severe asthma. | 2017 | BMC Microbiol. | pmid:28486933 |
| Savaris RF et al. | Antibiotic therapy for pelvic inflammatory disease. | 2017 | Cochrane Database Syst Rev | pmid:28436019 |
| Snelling PJ et al. | Rhabdomyolysis Complicating Typhoid Fever in A Child and Review of the Literature. | 2017 | Pediatr. Infect. Dis. J. | pmid:28430751 |
| Ito A et al. | A Case of Community-Acquired Pneumonia Due to Legionella pneumophila Serogroup 9 Wherein Initial Treatment with Single-Dose Oral Azithromycin Appeared Useful. | 2017 | Jpn. J. Infect. Dis. | pmid:28890505 |
| Saiz JC and MartÃn-Acebes MA | Reply to Iannetta et al., "Azithromycin Shows Anti-Zika Virus Activity in Human Glial Cells". | 2017 | Antimicrob. Agents Chemother. | pmid:28839084 |
| Iannetta M et al. | Azithromycin Shows Anti-Zika Virus Activity in Human Glial Cells. | 2017 | Antimicrob. Agents Chemother. | pmid:28839081 |
| Hallström H et al. | Open flap debridement of peri-implantitis with or without adjunctive systemic antibiotics: A randomized clinical trial. | 2017 | J. Clin. Periodontol. | pmid:28836279 |
| Lee SC et al. | Comparative effectiveness of azithromycin for treating scrub typhus: A PRISMA-compliant systematic review and meta-analysis. | 2017 | Medicine (Baltimore) | pmid:28885357 |
| Mandhane PJ et al. | Treatment of preschool children presenting to the emergency department with wheeze with azithromycin: A placebo-controlled randomized trial. | 2017 | PLoS ONE | pmid:28771627 |
| Gifford J et al. | Decision support during electronic prescription to stem antibiotic overuse for acute respiratory infections: a long-term, quasi-experimental study. | 2017 | BMC Infect. Dis. | pmid:28760143 |
| Ragusa A and Svelato A | Adjunctive Azithromycin Prophylaxis for Cesarean Delivery. | 2017 | N. Engl. J. Med. | pmid:28079335 |
| Upadhyay K et al. | Combination therapy with ampicillin and azithromycin improved outcomes in a mouse model of group B streptococcal sepsis. | 2017 | PLoS ONE | pmid:28759625 |
| Greig JR and Jones L | Adjunctive Azithromycin Prophylaxis for Cesarean Delivery. | 2017 | N. Engl. J. Med. | pmid:28079334 |
| Pavlova A et al. | Toward the rational design of macrolide antibiotics to combat resistance. | 2017 | Chem Biol Drug Des | pmid:28419786 |
| Asano N et al. | Limited Azithromycin Localization to Rabbit Meibomian Glands Revealed by LC-MS-Based Bioanalysis and DESI Imaging. | 2017 | Biol. Pharm. Bull. | pmid:28867744 |
| Seyama S et al. | Amino Acid Substitution in the Major Multidrug Efflux Transporter Protein AcrB Contributes to Low Susceptibility to Azithromycin in Haemophilus influenzae. | 2017 | Antimicrob. Agents Chemother. | pmid:28848006 |
| Yoon HY et al. | Clinical significance of QT-prolonging drug use in patients with MDR-TB or NTM disease. | 2017 | Int. J. Tuberc. Lung Dis. | pmid:28826448 |
| Whiley DM et al. | Molecular Antimicrobial Resistance Surveillance for Neisseria gonorrhoeae, Northern Territory, Australia. | 2017 | Emerging Infect. Dis. | pmid:28820128 |
| Fage C et al. | The combination of oseltamivir with azithromycin does not show additional benefits over oseltamivir monotherapy in mice infected with influenza A(H1N1)pdm2009 virus. | 2017 | J. Med. Virol. | pmid:28792077 |
| Agarwal E et al. | Locally Delivered 0.5% Azithromycin as an Adjunct to Non-Surgical Treatment in Patients With Chronic Periodontitis With Type 2 Diabetes: A Randomized Controlled Clinical Trial. | 2017 | J. Periodontol. | pmid:22655911 |
| Saini H et al. | Azithromycin-Ciprofloxacin-Impregnated Urinary Catheters Avert Bacterial Colonization, Biofilm Formation, and Inflammation in a Murine Model of Foreign-Body-Associated Urinary Tract Infections Caused by Pseudomonas aeruginosa. | 2017 | Antimicrob. Agents Chemother. | pmid:28031194 |
| Bouklouze A et al. | Azithromycin assay in drug formulations: Validation of a HPTLC method with a quadratic polynomial calibration model using the accuracy profile approach. | 2017 | Ann Pharm Fr | pmid:27692351 |
| Katz AR et al. | Cluster of Neisseria gonorrhoeae Isolates With High-level Azithromycin Resistance and Decreased Ceftriaxone Susceptibility, Hawaii, 2016. | 2017 | Clin. Infect. Dis. | pmid:28549097 |
| Lee N et al. | Anti-inflammatory effects of adjunctive macrolide treatment in adults hospitalized with influenza: A randomized controlled trial. | 2017 | Antiviral Res. | pmid:28535933 |
| Allen GP and Harris KA | Resistance Selection in Shigella flexneri by Azithromycin, Ceftriaxone, Ciprofloxacin, Levofloxacin, and Moxifloxacin. | 2017 | Antimicrob. Agents Chemother. | pmid:28483960 |
| Waetzig V et al. | Neurodegenerative effects of azithromycin in differentiated PC12 cells. | 2017 | Eur. J. Pharmacol. | pmid:28479141 |
| Quinn KL et al. | Macrolides, Digoxin Toxicity and the Risk of Sudden Death: A Population-Based Study. | 2017 | Drug Saf | pmid:28421551 |