Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Tick Bites D064927 1 associated lipids
Chlamydial Pneumonia D061387 2 associated lipids
Reproductive Tract Infections D060737 1 associated lipids
Granulomatous Mastitis D058890 1 associated lipids
Trichiasis D058457 1 associated lipids
Asymptomatic Infections D058345 1 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Neglected Diseases D058069 3 associated lipids
Corneal Endothelial Cell Loss D055954 1 associated lipids
Multiple Pulmonary Nodules D055613 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

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What functions are associated with Azithramycine?


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Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Lo Bue AM et al. Antimicrobial interference of a subinhibitory concentration of azithromycin on fimbrial production of Porphyromonas gingivalis. 1997 J. Antimicrob. Chemother. pmid:9421312
Kobayashi I et al. A new semi-solid agar dilution method for determining amoxycillin, clarithromycin and azithromycin MICs for Helicobacter pylori isolates. 1997 J. Antimicrob. Chemother. pmid:9421321
Champney WS and Burdine R Azithromycin and clarithromycin inhibition of 50S ribosomal subunit formation in Staphylococcus aureus cells. 1998 Curr. Microbiol. pmid:9425251
Feldman C et al. Roxithromycin, clarithromycin, and azithromycin attenuate the injurious effects of bioactive phospholipids on human respiratory epithelium in vitro. 1997 Inflammation pmid:9429912
Gómez E et al. Treatment of cyclosporin-induced gingival hyperplasia with azithromycin. 1997 Nephrol. Dial. Transplant. pmid:9430874
[New ways of antibiotic therapy]. 1995 Internist (Berl) pmid:9431354
Nyström-Rosander C et al. Susceptibility of Chlamydia pneumoniae to azithromycin and doxycycline: methodological aspects on the determination of minimal inhibitory and minimal bactericidal concentrations. 1997 Scand. J. Infect. Dis. pmid:9435043
Hillis SD et al. Doxycycline and azithromycin for prevention of chlamydial persistence or recurrence one month after treatment in women. A use-effectiveness study in public health settings. 1998 Sex Transm Dis pmid:9437777
Edelstein PH Legionnaires' disease. 1998 N. Engl. J. Med. pmid:9441231
Kalenić S et al. Helicobacter pylori: in vitro induction of resistance to azithromycin. 1998 Jan-Feb Chemotherapy pmid:9444404
Malizia T et al. Periodontal tissue disposition of azithromycin. 1997 J. Periodontol. pmid:9444596
Nguyen MH et al. Potentiation of antifungal activity of amphotericin B by azithromycin against Aspergillus species. 1997 Eur. J. Clin. Microbiol. Infect. Dis. pmid:9447909
Bermudez LE et al. Emergence of Mycobacterium avium populations resistant to macrolides during experimental chemotherapy. 1998 Antimicrob. Agents Chemother. pmid:9449283
Roblin PM and Hammerschlag MR Microbiologic efficacy of azithromycin and susceptibilities to azithromycin of isolates of Chlamydia pneumoniae from adults and children with community-acquired pneumonia. 1998 Antimicrob. Agents Chemother. pmid:9449287
Diculencu D et al. [The postantibiotic effect of azithromycin on respiratory pathogens]. 1996 Jul-Dec Rev Med Chir Soc Med Nat Iasi pmid:9455450
Gray GC et al. Weekly oral azithromycin as prophylaxis for agents causing acute respiratory disease. 1998 Clin. Infect. Dis. pmid:9455517
Andersen SL et al. Successful double-blinded, randomized, placebo-controlled field trial of azithromycin and doxycycline as prophylaxis for malaria in western Kenya. 1998 Clin. Infect. Dis. pmid:9455524
Chia JK et al. Azithromycin for the treatment of cat-scratch disease. 1998 Clin. Infect. Dis. pmid:9455538
Peterson J and Treadway G Impact of community-based azithromycin treatment of trachoma on carriage and resistance of Streptococcus pneumoniae. 1998 Clin. Infect. Dis. pmid:9455579
Holmberg SD et al. Possible effectiveness of clarithromycin and rifabutin for cryptosporidiosis chemoprophylaxis in HIV disease. HIV Outpatient Study (HOPS) Investigators. 1998 JAMA pmid:9459473
Gaydos CA et al. Molecular amplification assays to detect chlamydial infections in urine specimens from high school female students and to monitor the persistence of chlamydial DNA after therapy. 1998 J. Infect. Dis. pmid:9466530
Adair CD et al. Chlamydia in pregnancy: a randomized trial of azithromycin and erythromycin. 1998 Obstet Gynecol pmid:9469269
Vcev A et al. [Omeprazole and azithromycin with and without metronidazole in the eradication of Helicobacter pylori in duodenal ulcer disease]. 1997 Lijec Vjesn pmid:9471481
Lilley LL and Guanci R Distraction delays a dose. 1998 Am J Nurs pmid:9473978
Hahn DL et al. Evidence for Chlamydia pneumoniae infection in steroid-dependent asthma. 1998 Ann. Allergy Asthma Immunol. pmid:9475566
Jaffé A et al. Long-term azithromycin may improve lung function in children with cystic fibrosis. 1998 Lancet pmid:9482305
Russell TS et al. Eradication of Cryptosporidium in a child undergoing maintenance chemotherapy for leukemia using high dose azithromycin therapy. 1998 Jan-Feb J. Pediatr. Hematol. Oncol. pmid:9482419
Seelis RE and Dohmen W [Short-term (6 days) eradication of Helicobacter pylori infection in the practice of a health insurance physician]. 1998 Dtsch. Med. Wochenschr. pmid:9487294
Thalhammer F et al. Azithromycin-related toxic effects of digitoxin. 1998 Br J Clin Pharmacol pmid:9489601
Muhlestein JB et al. Infection with Chlamydia pneumoniae accelerates the development of atherosclerosis and treatment with azithromycin prevents it in a rabbit model. 1998 Circulation pmid:9495296
Woldtvedt BR et al. Possible increased anticoagulation effect of warfarin induced by azithromycin. 1998 Ann Pharmacother pmid:9496419
Hoge CW et al. Trends in antibiotic resistance among diarrheal pathogens isolated in Thailand over 15 years. 1998 Clin. Infect. Dis. pmid:9502453
Clancy CJ and Nguyen MH The combination of amphotericin B and azithromycin as a potential new therapeutic approach to fusariosis. 1998 J. Antimicrob. Chemother. pmid:9511049
Trevisani L et al. A four-day low dose triple therapy regimen for the treatment of Helicobacter pylori infection. 1998 Am. J. Gastroenterol. pmid:9517646
Bowden FJ and Savage J Donovanosis: treatment with azithromycin. 1998 Int J STD AIDS pmid:9518024
Oldfield EC et al. Once weekly azithromycin therapy for prevention of Mycobacterium avium complex infection in patients with AIDS: a randomized, double-blind, placebo-controlled multicenter trial. 1998 Clin. Infect. Dis. pmid:9524832
den Hollander JG et al. Comparison of pharmacodynamics of azithromycin and erythromycin in vitro and in vivo. 1998 Antimicrob. Agents Chemother. pmid:9527789
Fuentes F et al. Postanitbiotic and sub-MIC effects of azithromycin and isepamicin against Staphylococcus aureus and Escherichia coli. 1998 Antimicrob. Agents Chemother. pmid:9527796
Kashuba AD and Amsden GW Bronchopulmonary pharmacokinetics of clarithromycin and azithromycin. 1998 Antimicrob. Agents Chemother. pmid:9527816
Leri O et al. [Effects of the triple therapy in the eradication of Helicobacter pylori: comparison of 3 different antibiotics]. 1997 Clin Ter pmid:9528197
Socan M Treatment of atypical pneumonia with azithromycin: comparison of a 5-day and a 3-day course. 1998 J Chemother pmid:9531077
Dzelalija B et al. [Azithromycin in the prevention of Mediterranean spotted fever]. 1997 Lijec Vjesn pmid:9531759
Rajyaguru JM and Muszynski MJ Sensitization of Burkholderia cepacia to antibiotics by cationic drugs. 1998 J. Antimicrob. Chemother. pmid:9533472
Kemper CA et al. Immunomodulatory treatment of Mycobacterium avium complex bacteremia in patients with AIDS by use of recombinant granulocyte-macrophage colony-stimulating factor. 1998 J. Infect. Dis. pmid:9534963
Jucglà A et al. The use of azithromycin for cyclosporin-induced gingival overgrowth. 1998 Br. J. Dermatol. pmid:9536254
Karcioglu ZA et al. Pharmacokinetics of azithromycin in trachoma patients: serum and tear levels. 1998 Ophthalmology pmid:9544640
Mizutani S [Nontuberculous mycobacteriosis; the present status and in the future. Infection with human immunodeficiency virus (HIV) and nontuberculous mycobacteriosis]. 1998 Kekkaku pmid:9545702
Walsh T et al. Randomised controlled trial of prophylactic antibiotics before insertion of intrauterine devices. IUD Study Group. 1998 Lancet pmid:9546505
Chakrabarti MK et al. Evaluation of different antibiotics in inhibiting colonization of Vibrio cholerae O1 and O139 in the rabbit intestine. 1998 Mar-Apr Chemotherapy pmid:9551241
Hoepelman IM et al. A short (3-day) course of azithromycin tablets versus a 10-day course of amoxycillin-clavulanic acid (co-amoxiclav) in the treatment of adults with lower respiratory tract infections and effects on long-term outcome. 1997 Int. J. Antimicrob. Agents pmid:9552709