Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Airway Obstruction D000402 13 associated lipids
Stomach Ulcer D013276 75 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Hearing Loss, Sensorineural D006319 8 associated lipids
Otitis Media D010033 12 associated lipids
Carcinoma, Basal Cell D002280 6 associated lipids
Bacterial Infections D001424 21 associated lipids
Pain D010146 64 associated lipids
Per page 10 20 50 100 | Total 276

PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Benson C Advances in the diagnosis and treatment of Mycobacterium avium complex (MAC) disease. 1994 AIDS Patient Care pmid:11362136
Ishida K et al. In vitro and in vivo activities of macrolides against Mycoplasma pneumoniae. 1994 Antimicrob. Agents Chemother. pmid:8031048
Cazzola M et al. Evaluation of lung tissue and hilar lymph node concentrations of azithromycin. 1994 Int J Clin Pharmacol Ther pmid:8004364
Hughes WT et al. Relative potency of 10 drugs with anti-Pneumocystis carinii activity in an animal model. 1994 J. Infect. Dis. pmid:7930735
Rehg JE A comparison of anticryptosporidial activity of paromomycin with that of other aminoglycosides and azithromycin in immunosuppressed rats. 1994 J. Infect. Dis. pmid:7930738
Spangler SK et al. Effect of CO2 on susceptibilities of anaerobes to erythromycin, azithromycin, clarithromycin, and roxithromycin. 1994 Antimicrob. Agents Chemother. pmid:8192445
Stamler DA et al. Azithromycin pharmacokinetics and intracellular concentrations in Legionella pneumophila-infected and uninfected guinea pigs and their alveolar macrophages. 1994 Antimicrob. Agents Chemother. pmid:8192446
Sifrim D et al. Comparison of the effects of midecamycin acetate and azithromycin on gastrointestinal motility in man. 1994 Drugs Exp Clin Res pmid:7956719
Dumas JL et al. Evaluation of the efficacy of prolonged administration of azithromycin in a murine model of chronic toxoplasmosis. 1994 J. Antimicrob. Chemother. pmid:7961197
Wallace MR et al. Azithromycin and typhoid. 1994 Lancet pmid:7911192
Pacor ML et al. [Safety of azithromycin in patients allergic to penicillin and cephalosporin]. 1994 Clin Ter pmid:8001336
Mizukane R et al. Comparative in vitro exoenzyme-suppressing activities of azithromycin and other macrolide antibiotics against Pseudomonas aeruginosa. 1994 Antimicrob. Agents Chemother. pmid:8203850
Wolinsky E Mycobacterium avium strains resistant to clarithromycin and azithromycin. 1994 Antimicrob. Agents Chemother. pmid:8031406
Trevisi P et al. Toxic pustuloderma associated with azithromycin. 1994 Clin. Exp. Dermatol. pmid:8033402
Bush MR and Rosa C Azithromycin and erythromycin in the treatment of cervical chlamydial infection during pregnancy. 1994 Obstet Gynecol pmid:8008325
Bermudez LE et al. Recombinant granulocyte-macrophage colony-stimulating factor enhances the effects of antibiotics against Mycobacterium avium complex infection in the beige mouse model. 1994 J. Infect. Dis. pmid:8158029
Rehg J New potential therapies for cryptosporidiosis: an analysis of variables affecting drug efficacy. 1994 Folia Parasitol. pmid:8050751
Godofsky EW Treatment of presumed cerebral toxoplasmosis with azithromycin. 1994 N. Engl. J. Med. pmid:8302335
Kelsey JJ et al. Presence of azithromycin breast milk concentrations: a case report. 1994 Am. J. Obstet. Gynecol. pmid:8178871
Rapp RP et al. New macrolide antibiotics: usefulness in infections caused by mycobacteria other than Mycobacterium tuberculosis. 1994 Ann Pharmacother pmid:7849341