Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Azithramycine
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
---|
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Sidhu H et al. | Risk assessment of biosolids-borne ciprofloxacin and azithromycin. | 2019 | Sci. Total Environ. | pmid:30463165 |
Sidhu H et al. | Plant toxicity and accumulation of biosolids-borne ciprofloxacin and azithromycin. | 2019 | Sci. Total Environ. | pmid:30340267 |
Sidhu H et al. | Retention-release of ciprofloxacin and azithromycin in biosolids and biosolids-amended soils. | 2019 | Sci. Total Environ. | pmid:30196217 |
Sidhu H et al. | Bioavailability of biosolids-borne ciprofloxacin and azithromycin to terrestrial organisms: Microbial toxicity and earthworm responses. | 2019 | Sci. Total Environ. | pmid:30195128 |
Pu Y et al. | Azithromycin ameliorates OVA-induced airway remodeling in Balb/c mice via suppression of epithelial-to-mesenchymal transition. | 2018 | Int. Immunopharmacol. | pmid:29567590 |
Abdulai AA et al. | Community-based mass treatment with azithromycin for the elimination of yaws in Ghana-Results of a pilot study. | 2018 | PLoS Negl Trop Dis | pmid:29566044 |
Pan H and Ba-Thein W | Diagnostic Accuracy of Global Pharma Health Fund Minilabâ„¢ in Assessing Pharmacopoeial Quality of Antimicrobials. | 2018 | Am. J. Trop. Med. Hyg. | pmid:29141717 |
Chatterjee S and Agrawal D | Azithromycin in the Management of Pythium insidiosum Keratitis. | 2018 | Cornea | pmid:29095755 |
Kelly C et al. | Macrolide antibiotics for bronchiectasis. | 2018 | Cochrane Database Syst Rev | pmid:29543980 |
Weston EJ et al. | Adherence to CDC Recommendations for the Treatment of Uncomplicated Gonorrhea - STD Surveillance Network, United States, 2016. | 2018 | MMWR Morb. Mortal. Wkly. Rep. | pmid:29698384 |
Keenan JD et al. | Azithromycin to Reduce Childhood Mortality in Sub-Saharan Africa. | 2018 | N. Engl. J. Med. | pmid:29694816 |
Tung NT et al. | Formulation and biopharmaceutical evaluation of bitter taste masking microparticles containing azithromycin loaded in dispersible tablets. | 2018 | Eur J Pharm Biopharm | pmid:28359878 |
Vermillion Maier ML and Tjeerdema RS | Azithromycin sorption and biodegradation in a simulated California river system. | 2018 | Chemosphere | pmid:29031188 |
Hong D et al. | [Atopic keratoconjunctivitis: One allergy may mask another. A clinical observation with two types of hypersensitivity reactions: IgE-mediated and non-IgE-mediated]. | 2018 | J Fr Ophtalmol | pmid:29567021 |
Goyal V et al. | Amoxicillin-clavulanate versus azithromycin for respiratory exacerbations in children with bronchiectasis (BEST-2): a multicentre, double-blind, non-inferiority, randomised controlled trial. | 2018 | Lancet | pmid:30241722 |
Thapa A et al. | Typhoid fever with isolated left lateral rectus palsy. | 2018 | BMJ Case Rep | pmid:30181402 |
Grewal TK et al. | Therapeutic implications of nano-encapsulated rifabutin, azithromycin & ethambutol against experimental infection in mice. | 2018 | Indian J. Med. Res. | pmid:30168492 |
Montazeri M et al. | Activities of anti-Toxoplasma drugs and compounds against tissue cysts in the last three decades (1987 to 2017), a systematic review. | 2018 | Parasitol. Res. | pmid:30088074 |
Smith-Norowitz TA et al. | Doxycycline suppresses Chlamydia pneumoniae induced interferon-gamma responses in peripheral blood mononuclear cells in children with allergic asthma. | 2018 | J. Infect. Chemother. | pmid:29615379 |
Rim JH et al. | Recent Increase in the Incidence of TEM-135 β-Lactamase-harboring Neisseria gonorrhoeae in Korea. | 2018 | Ann Lab Med | pmid:29611382 |