Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Azithramycine
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Luo L et al. | [Inhibition of airway mucous hypersecretion by azithromycin through matrix metalloproteinase 9]. | 2011 | Zhonghua Yi Xue Za Zhi | pmid:21600177 |
Wang H et al. | [Polymerase chain reaction in the detection of patients infected by Chlamydia trachomatis after treatment]. | 1997 | Zhonghua Yi Xue Za Zhi | pmid:9596935 |
Liu CL et al. | [Current infection of Mycoplasma pneumoniae in adults: clinical analysis of 13 hospitalized patients]. | 2006 | Zhonghua Yi Xue Za Zhi | pmid:16796860 |
Zhou LQ et al. | [Detection of bacterial 16S rRAN gene in EPS of men with chronic pelvic pain syndrome and its clinical significance]. | 2003 | Zhonghua Nan Ke Xue | pmid:12931366 |
Zhou WQ et al. | [Clinic efficacy of treating chronic prostatitis caused by Neisseria gonorrhoeae with azithromycin aspartic-acid injection]. | 2003 | Zhonghua Nan Ke Xue | pmid:12680331 |
Fang X et al. | [Inhibitory activity of azithromycin on biofilm synthesis and synergism between azithromycin and fleroxacin on Pseudomonas aeruginosa in biofilms]. | 1998 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:11360505 |
Nie W et al. | [The analysis of species identification and susceptibility testing of Mycobacterium abscessus]. | 2014 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:25262693 |
Zhou CM et al. | [Antimicrobial susceptibility of community-acquired respiratory tract pathogens isolated from patients in primary hospitals in Shanghai from 2007 to 2010]. | 2013 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:24047808 |
Bao F et al. | [The clinical characteristics, treatment and outcome of macrolide-resistant Mycoplasma pneumoniae pneumonia in children]. | 2013 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:24433804 |
Zhang BL and Yang L | [Azithromycin appears to enhance the therapeutic effects of steroids in patients with primary nephrotic syndrome during recurrence and/or relapse]. | 2011 | Zhonghua Er Ke Za Zhi | pmid:22336319 |
An N et al. | [Severe liver damage caused by intravenous infusion of azithromycin in a case]. | 2006 | Zhonghua Er Ke Za Zhi | pmid:16780660 |
Yin J et al. | [Mycoplasma pneumoniae-associated mucositis: a case report]. | 2014 | Zhonghua Er Ke Za Zhi | pmid:24969943 |
He S et al. | [Clinical analysis of scrub typhus-associated hemophagocytic syndrome]. | 2014 | Zhonghua Er Ke Za Zhi | pmid:25476431 |
Yang YZ | [Death of a case caused by anaphylaxis to azithromycin]. | 2004 | Zhonghua Er Ke Za Zhi | pmid:15733367 |
Li JG et al. | [Eperythrozoonosis complicated with hemophagocytic syndrome: report of four cases and review of literature]. | 2018 | Zhonghua Er Ke Za Zhi | pmid:29614573 |
Liu H et al. | [A systematic review of the therapy for Mycoplasma pneumoniae infections in children]. | 2016 | Zhonghua Er Ke Za Zhi | pmid:26875461 |
Chen GF et al. | [Follow up of 16 cases with congenital toxoplasmosis treated with azithromycin]. | 2004 | Zhonghua Er Ke Za Zhi | pmid:14990100 |
Liu WE et al. | [Treatment of ureaplasma urealyticum infection patients of Qi deficiency blood stasis syndrome by pengyan pill: a clinical observation]. | 2013 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:23905372 |
Tang HX et al. | [Clinical experience on treating Toxoplasma gondii infection during pregnancy by using acetyl spiramycin combined with azithromycin]. | 2013 | Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi | pmid:24490384 |
Yin WD et al. | [In vivo effect of dihydroartemisinin and azithromycin on the ultrastructure of Toxoplasma gondii tachyzoites]. | 2009 | Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi | pmid:20066989 |
Chen QF and Zhang YW | [Clinical effect of Saccharomyces boulardii powder combined with azithromycin sequential therapy in treatment of children with diarrhea secondary to Mycoplasma pneumoniae pneumonia]. | 2018 | Zhongguo Dang Dai Er Ke Za Zhi | pmid:29429459 |
Zhang XR et al. | [Protection of azithromycin against pulmonary II epithelial cell injuries induced by cigarette smoke extract and relevant mechanisms]. | 2007 | Zhongguo Dang Dai Er Ke Za Zhi | pmid:17306081 |
Zhang JX et al. | [Resistant analysis and cultivation results of 3 160 blood specimen]. | 2005 | Zhong Nan Da Xue Xue Bao Yi Xue Ban | pmid:15871208 |
Dolgushin II et al. | [Immunological and microbiological aspects of low intensity laser effect on the factors of local immunity of the reproductive tract in women with chlamydia infection]. | 2006 Jul-Aug | Zh. Mikrobiol. Epidemiol. Immunobiol. | pmid:16941885 |
Schilling F and Wagner AD | [Azithromycin: an anti-inflammatory effect in chronic recurrent multifocal osteomyelitis? A preliminary report]. | 2000 | Z Rheumatol | pmid:11142932 |
Salgado HR and Roncari AF | Microbiological assay for the determination of azithromycin in ophthalmic solutions. | 2005 | Yao Xue Xue Bao | pmid:16144322 |
Wang JS et al. | [Preparation of lung targeting azithromycin liposomes and its tissue distribution in mice]. | 2005 | Yao Xue Xue Bao | pmid:15952603 |
Haruki Y et al. | [Investigation of Intravenous Azithromycin Treatment Safety When Reducing Solvent for Intensive Care Unit Patients]. | 2015 | Yakugaku Zasshi | pmid:26234357 |
Salimi A et al. | Toxicity of macrolide antibiotics on isolated heart mitochondria: a justification for their cardiotoxic adverse effect. | 2016 | Xenobiotica | pmid:26068526 |
Dolezelova E et al. | Resveratrol modifies biliary secretion of cholephilic compounds in sham-operated and cholestatic rats. | 2017 | World J. Gastroenterol. | pmid:29209109 |
Ivashkin VT et al. | Azithromycin in a triple therapy for H.pylori eradication in active duodenal ulcer. | 2002 | World J. Gastroenterol. | pmid:12378634 |
Dong J et al. | Azithromycin-containing versus standard triple therapy for Helicobacter pylori eradication: a meta-analysis. | 2009 | World J. Gastroenterol. | pmid:20027685 |
Babic Z et al. | Increased activity of Pgp multidrug transporter in patients with Helicobacter pylori infection. | 2005 | World J. Gastroenterol. | pmid:15884110 |
Mousavi S et al. | Azithromycin in one week quadruple therapy for H pylori eradication in Iran. | 2006 | World J. Gastroenterol. | pmid:16874871 |
Shan LS et al. | Effects of methylprednisolone or immunoglobulin when added to standard treatment with intravenous azithromycin for refractory Mycoplasma pneumoniae pneumonia in children. | 2017 | World J Pediatr | pmid:28130749 |
Haggerty CL and Ness RB | Diagnosis and treatment of pelvic inflammatory disease. | 2008 | Womens Health (Lond Engl) | pmid:19072503 |
Sawhney N | MAC prophylaxis in the era of polypharmacy. | 1999 May-Jun | WMJ | pmid:10414219 |
Subedi Y | Around Manaslu Ultramarathon: Diarrhea Is Still the King. | 2017 | Wilderness Environ Med | pmid:28735656 |
Kratzer C et al. | Comparative activities of antibiotics against intracellular non-typeable Haemophilus influenzae. | 2007 | Wien. Klin. Wochenschr. | pmid:17571234 |
Hunfeld KP and Brade V | Antimicrobial susceptibility of Borrelia burgdorferi sensu lato: what we know, what we don't know, and what we need to know. | 2006 | Wien. Klin. Wochenschr. | pmid:17160604 |
Arnez M et al. | Solitary erythema migrans in children: comparison of treatment with azithromycin and phenoxymethylpenicillin. | 2002 | Wien. Klin. Wochenschr. | pmid:12422590 |
Maraspin V et al. | Development of erythema migrans in spite of treatment with antibiotics after a tick bite. | 2002 | Wien. Klin. Wochenschr. | pmid:12422612 |
MUW researcher of the month Franz Ratzinger. | 2016 | Wien. Klin. Wochenschr. | pmid:27113348 | |
[Newly approved specialty drugs in Austria and new knowledge about currently available specialty drugs. Zithromax capsules, dried syrup]. | 1994 | Wien. Klin. Wochenschr. | pmid:7975673 | |
Schilling F | [SAPHO syndrome. A contribution to discussion]. | 2003 | Wien. Klin. Wochenschr. | pmid:12674695 |
Cerar D et al. | Azithromycin for acute Q fever in pregnancy. | 2009 | Wien. Klin. Wochenschr. | pmid:19657611 |
Strle F and Maraspin V | Is azithromycin treatment associated with prolongation of the Q-Tc interval? | 2002 | Wien. Klin. Wochenschr. | pmid:12708094 |
Vossen MG et al. | [In vitro interaction studies of azithromycin and dihydroartemisinin in Plasmodium falciparum isolates from Bangladesh]. | 2007 | Wien. Klin. Wochenschr. | pmid:17987362 |
Wenisch C | [Pharmacokinetic effects of antibiotics on the development of bacterial resistance particularly in reference to azithromycin]. | 2000 | Wien Med Wochenschr | pmid:10756595 |
Kanatani MS and Guglielmo BJ | The new macrolides. Azithromycin and clarithromycin. | 1994 | West. J. Med. | pmid:8128699 |
Swanston WH et al. | Single dose (direct observed) azithromycin therapy for Neisseria gonorrhoeae and Chlamydia trachomatis in STD clinic attenders with genital discharge in Trinidad and Tobago. | 2001 | West Indian Med J | pmid:11769023 |
Odugbemi T et al. | Single oral dose of azithromycin for therapy of susceptible sexually transmitted diseases: a multicenter open evaluation. | 1993 Jul-Sep | West Afr J Med | pmid:8312208 |
Yasojima M et al. | Occurrence of levofloxacin, clarithromycin and azithromycin in wastewater treatment plant in Japan. | 2006 | Water Sci. Technol. | pmid:16862794 |
Walters E et al. | Occurrence and loss over three years of 72 pharmaceuticals and personal care products from biosolids-soil mixtures in outdoor mesocosms. | 2010 | Water Res. | pmid:20728197 |
Yazdanbakhsh AR et al. | Reduction of non-Betalactam Antibiotics COD by Combined Coagulation and Advanced Oxidation Processes. | 2016 | Water Environ. Res. | pmid:28661328 |
Garasiuta EG | [Surgical treatment of ulnar and pre-patellar bursitis under ambulatory conditions]. | 2000 | Voen Med Zh | pmid:12886538 |
Klochkov OI et al. | [The use of azithromycin in prophylaxis of respiratory infections occurred in the organized collectives, clinical sequelae]. | 2004 | Voen Med Zh | pmid:15675752 |
Guchev IA et al. | [Prophylaxis of pneumonia occurring outside the hospital in organized groups]. | 2003 | Voen Med Zh | pmid:12722363 |
Guchev IA et al. | [Effect of chemoprophylaxis on pneumonia incidence in organized groups]. | 2003 | Voen Med Zh | pmid:12722514 |
Guo Y et al. | Chlamydiaphage φCPG1 Capsid Protein Vp1 Inhibits Chlamydia trachomatis Growth via the Mitogen-Activated Protein Kinase Pathway. | 2016 | Viruses | pmid:27089359 |
Moshkani SK and Dalimi A | Evaluation of the efficacy of atovaquone alone or in combination with azithromycin against acute murine toxoplasmosis. | 2000 | Vet. Res. Commun. | pmid:10836275 |
Hetzel U et al. | Mycobacterium malmoense as an extrapulmonary pathogen of cats. | 2012 | Vet. Rec. | pmid:22865116 |
Venner M et al. | Comparison of tulathromycin, azithromycin and azithromycin-rifampin for the treatment of mild pneumonia associated with Rhodococcus equi. | 2013 | Vet. Rec. | pmid:24106244 |
Azmanis P et al. | First detection of Cryptosporidium parvum in falcons (Falconiformes): Diagnosis, molecular sequencing, therapeutic trial and epidemiological assessment of a possible emerging disease in captive falcons. | 2018 | Vet. Parasitol. | pmid:29559142 |
FitzGerald L et al. | Morphological and molecular characterisation of a mixed Cryptosporidium muris/Cryptosporidium felis infection in a cat. | 2011 | Vet. Parasitol. | pmid:21044819 |
Di Cicco MF et al. | Re-emergence of Babesia conradae and effective treatment of infected dogs with atovaquone and azithromycin. | 2012 | Vet. Parasitol. | pmid:22305297 |
Berghaus LJ et al. | Mutant prevention concentration and mutant selection window for 10 antimicrobial agents against Rhodococcus equi. | 2013 | Vet. Microbiol. | pmid:23915992 |
Venner M et al. | Efficacy of azithromycin in preventing pulmonary abscesses in foals. | 2009 | Vet. J. | pmid:18023599 |
Zur G et al. | Azithromycin pharmacokinetics in the serum and its distribution to the skin in healthy dogs and dogs with pyoderma. | 2014 | Vet. J. | pmid:24472431 |
Cárceles CM et al. | Tissue disposition of azithromycin after intravenous and intramuscular administration to rabbits. | 2007 | Vet. J. | pmid:16904354 |
Venner M et al. | Failure of antimicrobial therapy to accelerate spontaneous healing of subclinical pulmonary abscesses on a farm with endemic infections caused by Rhodococcus equi. | 2012 | Vet. J. | pmid:21924651 |
Venner M et al. | Evaluation of tulathromycin in the treatment of pulmonary abscesses in foals. | 2007 | Vet. J. | pmid:17045497 |
Bernstein JA | Re: Azithromycin therapy of papillomatosis in dogs: a prospective, randomized, double-blinded, placebo-controlled clinical trial. | 2009 | Vet. Dermatol. | pmid:19320876 |
YaÄŸci BB et al. | Azithromycin therapy of papillomatosis in dogs: a prospective, randomized, double-blinded, placebo-controlled clinical trial. | 2008 | Vet. Dermatol. | pmid:18494759 |
Rosenberg A et al. | Evaluation of azithromycin in systemic and toothpaste forms for the treatment of ciclosporin-associated gingival overgrowth in dogs. | 2013 | Vet. Dermatol. | pmid:23668859 |
Yager JA et al. | Bacillary angiomatosis in an immunosuppressed dog. | 2010 | Vet. Dermatol. | pmid:20374571 |
Barr BS | Rhodococcus equi pneumonia in a foal. | 2006 | Vet. Clin. North Am. Equine Pract. | pmid:16627120 |
Giguère S | Treatment of Infections Caused by Rhodococcus equi. | 2017 | Vet. Clin. North Am. Equine Pract. | pmid:28161038 |
Lobzin IuV et al. | [New achievements in the diagnosis and treatment of disseminated urogenital chlamydiosis]. | 2003 | Vestn. Akad. Med. Nauk SSSR | pmid:14598508 |
Aznabaev MT et al. | [Use of cycloferon in a combined treatment of chlamydial conjunctivitis]. | 2003 Jan-Feb | Vestn Oftalmol | pmid:12608044 |
Yoon HJ et al. | Cervical lymphadenitis in a patient coinfected with Toxoplasma gondii and Bartonella henselae. | 2010 | Vector Borne Zoonotic Dis. | pmid:19874186 |
McGready R et al. | First report of an Orientia tsutsugamushi type TA716-related scrub typhus infection in Thailand. | 2010 | Vector Borne Zoonotic Dis. | pmid:19492945 |
Puri K et al. | Bartonella Osteomyelitis of the Acetabulum: Case Report and Review of the Literature. | 2015 | Vector Borne Zoonotic Dis. | pmid:26273806 |
Postma MJ et al. | Cost-effectiveness of partner pharmacotherapy in screening women for asymptomatic infection with Chlamydia Trachomatis. | 2001 May-Jun | Value Health | pmid:11705188 |
Zhou L et al. | Serotype distribution and antibiotic resistance of 140 pneumococcal isolates from pediatric patients with upper respiratory infections in Beijing, 2010. | 2011 | Vaccine | pmid:21839135 |
Friesen J and Matuschewski K | Comparative efficacy of pre-erythrocytic whole organism vaccine strategies against the malaria parasite. | 2011 | Vaccine | pmid:21787828 |
Potts JM et al. | Association of chronic urinary symptoms in women and Ureaplasma urealyticum. | 2000 | Urology | pmid:10736488 |
Kondrat'eva IuS and NeÄmark AI | [Current approaches to the treatment of non-gonococcal urethritis in men]. | 2011 Jul-Aug | Urologiia | pmid:22066239 |
Shperling NV et al. | [Treatment of chlamydial infection in chronic prostatitis]. | 2011 Jul-Aug | Urologiia | pmid:22066242 |
Proskurin AA et al. | [Using safocid for antibiotic prophylaxis in minimally-invasive endoscopic operations and manipulations]. | 2010 Nov-Dec | Urologiia | pmid:21427992 |
Parent M | [Initial empiric treatment of pneumonia and the new antibiotics]. | 1994 | Union Med Can | pmid:8109061 |
Lisby JG et al. | [Bacteremia and meningitis caused by Streptococcus pneumoniae during treatment with azithromycin]. | 2002 | Ugeskr. Laeg. | pmid:12043408 |
Uldum SA et al. | [Macrolide resistance in Mycoplasma pneumoniae by recurrence and extended illness]. | 2012 | Ugeskr. Laeg. | pmid:22409896 |
Friis HM | [Azithromycin--an exciting new antibiotic]. | 1995 | Ugeskr. Laeg. | pmid:7831724 |
Dessau RB | [Azithromycin]. | 1995 | Ugeskr. Laeg. | pmid:7831733 |
Andersen SE et al. | [Failed azithromycin treatment of Chlamydia trachomatis infection]. | 2001 | Ugeskr. Laeg. | pmid:11810790 |
EmiralioÄŸlu N et al. | Long term azithromycin therapy in patients with cystic fibrosis. | 2016 | Turk. J. Pediatr. | pmid:27922234 |
Biner B et al. | The comparison of single-dose ceftriaxone, five-day azithromycin, and ten-day amoxicillin/clavulanate for the treatment of children with acute otitis media. | 2007 Oct-Dec | Turk. J. Pediatr. | pmid:18246740 |
AltintaÅŸ E et al. | Comparison of ranitidine bismuth citrate, tetracycline and metronidazole with ranitidine bismuth citrate and azithromycin for the eradication of Helicobacter pylori in patients resistant to PPI based triple therapy. | 2004 | Turk J Gastroenterol | pmid:15334317 |
Oztürk K et al. | Diagnosis of helicobacter pylori infection. | 2014 | Turk J Gastroenterol | pmid:25141328 |