Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Ectodermal Dysplasia D004476 1 associated lipids
Aphasia, Broca D001039 1 associated lipids
T-Lymphocytopenia, Idiopathic CD4-Positive D018344 1 associated lipids
Acquired Hyperostosis Syndrome D020083 1 associated lipids
Myelitis, Transverse D009188 1 associated lipids
Epiglottitis D004826 1 associated lipids
Tick Bites D064927 1 associated lipids
Eisenmenger Complex D004541 1 associated lipids
Furcation Defects D017823 1 associated lipids
Granulomatous Mastitis D058890 1 associated lipids
Focal Nodular Hyperplasia D020518 1 associated lipids
Syncope, Vasovagal D019462 1 associated lipids
Achondroplasia D000130 1 associated lipids
Pseudolymphoma D019310 1 associated lipids
Leishmaniasis, Mucocutaneous D007897 1 associated lipids
Tracheobronchomalacia D055089 1 associated lipids
Trismus D014313 1 associated lipids
Pneumocystis Infections D016720 1 associated lipids
Trichiasis D058457 1 associated lipids
Reproductive Tract Infections D060737 1 associated lipids
Per page 10 20 50 100 | Total 276

PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with Azithramycine

Download all related citations
Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Kanazawa S et al. Azithromycin and bronchiolitis obliterans. 2004 Am. J. Respir. Crit. Care Med. pmid:14982826
Tsai WC et al. Azithromycin blocks neutrophil recruitment in Pseudomonas endobronchial infection. 2004 Am. J. Respir. Crit. Care Med. pmid:15361366
Jeong BH et al. Intermittent antibiotic therapy for nodular bronchiectatic Mycobacterium avium complex lung disease. 2015 Am. J. Respir. Crit. Care Med. pmid:25393520
Restrepo MI and Anzueto A Reply: Azithromycin: We're there! 2014 Am. J. Respir. Crit. Care Med. pmid:25360733
Albert RK et al. Azithromycin: We're there! 2014 Am. J. Respir. Crit. Care Med. pmid:25360732
Verleden GM et al. Azithromycin reduces airway neutrophilia and interleukin-8 in patients with bronchiolitis obliterans syndrome. 2006 Am. J. Respir. Crit. Care Med. pmid:16741151
Barker PM et al. Effect of macrolides on in vivo ion transport across cystic fibrosis nasal epithelium. 2005 Am. J. Respir. Crit. Care Med. pmid:15657462
Choi GE et al. Macrolide treatment for Mycobacterium abscessus and Mycobacterium massiliense infection and inducible resistance. 2012 Am. J. Respir. Crit. Care Med. pmid:22878281
Restrepo MI and Anzueto A Macrolide antibiotics for prevention of chronic obstructive pulmonary disease exacerbations: are we there yet? 2014 Am. J. Respir. Crit. Care Med. pmid:24983214
Binder AM et al. Epidemiology of nontuberculous mycobacterial infections and associated chronic macrolide use among persons with cystic fibrosis. 2013 Am. J. Respir. Crit. Care Med. pmid:23927602
Lococo F et al. Hemoptysis and Progressive Dyspnea in a 67-Year-Old Woman with History of Renal Transplantation. 2016 Am. J. Respir. Crit. Care Med. pmid:26681504
Angel LF et al. Azithromycin in bronchiolitis obliterans: is the evidence strong enough? 2006 Am. J. Respir. Crit. Care Med. pmid:16467178
Han MK et al. Predictors of chronic obstructive pulmonary disease exacerbation reduction in response to daily azithromycin therapy. 2014 Am. J. Respir. Crit. Care Med. pmid:24779680
Mertens V et al. Bile acids aspiration reduces survival in lung transplant recipients with BOS despite azithromycin. 2011 Am. J. Transplant. pmid:21272237
Glanville AR CLAD: does the Emperor have new clothes? 2014 Am. J. Transplant. pmid:25394597
Vos R et al. Azithromycin and the treatment of lymphocytic airway inflammation after lung transplantation. 2014 Am. J. Transplant. pmid:25394537
Verleden SE et al. Lymphocytic bronchiolitis after lung transplantation is associated with daily changes in air pollution. 2012 Am. J. Transplant. pmid:22682332
Greer M et al. Phenotyping established chronic lung allograft dysfunction predicts extracorporeal photopheresis response in lung transplant patients. 2013 Am. J. Transplant. pmid:23406373
Robertson AG et al. Targeting allograft injury and inflammation in the management of post-lung transplant bronchiolitis obliterans syndrome. 2009 Am. J. Transplant. pmid:19459806
Ruttens D et al. Prophylactic Azithromycin Therapy After Lung Transplantation: Post hoc Analysis of a Randomized Controlled Trial. 2016 Am. J. Transplant. pmid:26372728