| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Airway Obstruction | D000402 | 13 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Diarrhea | D003967 | 32 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Hearing Loss, Sensorineural | D006319 | 8 associated lipids |
| Otitis Media | D010033 | 12 associated lipids |
| Carcinoma, Basal Cell | D002280 | 6 associated lipids |
| Bacterial Infections | D001424 | 21 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Stomach Diseases | D013272 | 7 associated lipids |
| Genital Diseases, Female | D005831 | 7 associated lipids |
| Lung Diseases | D008171 | 37 associated lipids |
| Sarcoidosis | D012507 | 13 associated lipids |
| Hyperglycemia | D006943 | 21 associated lipids |
| Carcinoma, Squamous Cell | D002294 | 14 associated lipids |
| Skin Neoplasms | D012878 | 12 associated lipids |
| Burns | D002056 | 34 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Colitis | D003092 | 69 associated lipids |
Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Yazdanbakhsh AR et al. | Reduction of non-Betalactam Antibiotics COD by Combined Coagulation and Advanced Oxidation Processes. | 2016 | Water Environ. Res. | pmid:28661328 |
| Salimi A et al. | Toxicity of macrolide antibiotics on isolated heart mitochondria: a justification for their cardiotoxic adverse effect. | 2016 | Xenobiotica | pmid:26068526 |
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| Gawin A et al. | Mildly pruritic palmar rash. | 2016 | J Fam Pract | pmid:28087868 |
| Martande SS et al. | Clinical and microbiological effects of systemic azithromycin in adjunct to nonsurgical periodontal therapy in treatment of Aggregatibacter actinomycetemcomitans associated periodontitis: a randomized placebo-controlled clinical trial. | 2016 | J Investig Clin Dent | pmid:25044531 |
| Berkowitz ST et al. | Resolution of spontaneous hemoabdomen secondary to peliosis hepatis following surgery and azithromycin treatment in a Bartonella species infected dog. | 2016 | J Vet Emerg Crit Care (San Antonio) | pmid:27074964 |
| MartÃn JM et al. | Azithromycin for the Treatment of Ciclosporin-Induced Gingival Hyperplasia. | 2016 | Actas Dermosifiliogr | pmid:26996332 |
| Petrelli F et al. | Poly(ADP-ribose) polymerase is not involved in the neuroprotection exerted by azithromycin against ischemic stroke in mice. | 2016 | Eur. J. Pharmacol. | pmid:27663279 |
| Gerhardt P et al. | [Male urethritis]. | 2016 | Ann Dermatol Venereol | pmid:27776813 |
| Dupin N et al. | [Chlamydia trachomatis]. | 2016 | Ann Dermatol Venereol | pmid:27773503 |
| Gong L et al. | Clinical effect of treating secondary asthma attacks of children Mycoplasma pneumoniae with combined therapy of montelukast and azithromycin. | 2016 | Eur Rev Med Pharmacol Sci | pmid:28051240 |
| Alcaraz I et al. | [Mycoplasma genitalium]. | 2016 | Ann Dermatol Venereol | pmid:27773499 |
| Lin SJ et al. | Azithromycin modulates immune response of human monocyte-derived dendritic cells and CD4 T cells. | 2016 | Int. Immunopharmacol. | pmid:27664570 |
| Liu X et al. | Novel antimicrobial peptide-modified azithromycin-loaded liposomes against methicillin-resistant Staphylococcus aureus. | 2016 | Int J Nanomedicine | pmid:28008253 |
| van den Berg GF et al. | Chlamydia screening and prophylactic treatment in termination of pregnancy clinics in the Netherlands and Great Britain: a qualitative study. | 2016 | Eur J Contracept Reprod Health Care | pmid:27701927 |
| Hirasawa K et al. | Macrolide Antibiotics Exhibit Cytotoxic Effect under Amino Acid-Depleted Culture Condition by Blocking Autophagy Flux in Head and Neck Squamous Cell Carcinoma Cell Lines. | 2016 | PLoS ONE | pmid:27977675 |
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| Zhao X et al. | Sensitive and Simplified Detection of Antibiotic Influence on the Dynamic and Versatile Changes of Fecal Short-Chain Fatty Acids. | 2016 | PLoS ONE | pmid:27907030 |
| Zeng J et al. | Mechanism of azithromycin inhibition of HSL synthesis in Pseudomonas aeruginosa. | 2016 | Sci Rep | pmid:27075730 |
| Caumes E et al. | [Donovanosis (granuloma inguinale)]. | 2016 | Ann Dermatol Venereol | pmid:27773509 |
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| Zhu XH et al. | Viral and Bacterial Etiology of Acute Diarrhea among Children under 5 Years of Age in Wuhan, China. | 2016 | Chin. Med. J. | pmid:27503019 |
| Zhao M et al. | Comparison of minocycline and azithromycin for the treatment of mild scrub typhus in northern China. | 2016 | Int. J. Antimicrob. Agents | pmid:27449540 |
| Dukers-Muijrers NH et al. | Design of the FemCure study: prospective multicentre study on the transmission of genital and extra-genital Chlamydia trachomatis infections in women receiving routine care. | 2016 | BMC Infect. Dis. | pmid:27502928 |
| Huang SW et al. | Azithromycin impairs TLR7 signaling in dendritic cells and improves the severity of imiquimod-induced psoriasis-like skin inflammation in mice. | 2016 | J. Dermatol. Sci. | pmid:27449383 |
| Yoshioka D et al. | Efficacy of β-Lactam-plus-Macrolide Combination Therapy in a Mouse Model of Lethal Pneumococcal Pneumonia. | 2016 | Antimicrob. Agents Chemother. | pmid:27480866 |
| Jacobsson S et al. | WGS analysis and molecular resistance mechanisms of azithromycin-resistant (MIC >2 mg/L) Neisseria gonorrhoeae isolates in Europe from 2009 to 2014. | 2016 | J. Antimicrob. Chemother. | pmid:27432597 |
| Jeong BH et al. | Peak Plasma Concentration of Azithromycin and Treatment Responses in Mycobacterium avium Complex Lung Disease. | 2016 | Antimicrob. Agents Chemother. | pmid:27480854 |
| de Zwart L et al. | Ibrutinib Dosing Strategies Based on Interaction Potential of CYP3A4 Perpetrators Using Physiologically Based Pharmacokinetic Modeling. | 2016 | Clin. Pharmacol. Ther. | pmid:27367453 |
| Abeles SR et al. | Microbial diversity in individuals and their household contacts following typical antibiotic courses. | 2016 | Microbiome | pmid:27473422 |
| Lockington D | Oral azithromycin and blepharitis: symptoms and signs improve, so where are the publications? | 2016 | Clin. Experiment. Ophthalmol. | pmid:27356302 |
| Zhu B et al. | High Resistance to Azithromycin in Clinical Samples from Patients with Sexually Transmitted Diseases in Guangxi Zhuang Autonomous Region, China. | 2016 | PLoS ONE | pmid:27467164 |
| Miyake H et al. | Meibomian Gland Dysfunction Model in Hairless Mice Fed a Special Diet With Limited Lipid Content. | 2016 | Invest. Ophthalmol. Vis. Sci. | pmid:27327582 |
| Kobbernagel HE et al. | Study protocol, rationale and recruitment in a European multi-centre randomized controlled trial to determine the efficacy and safety of azithromycin maintenance therapy for 6Â months in primary ciliary dyskinesia. | 2016 | BMC Pulm Med | pmid:27450411 |
| Sacks HS | In older adults, macrolide antibiotics were not linked to increased risk for ventricular arrhythmia. | 2016 | Ann. Intern. Med. | pmid:27323264 |
| Goh YS et al. | Neutralizing Antibodies against Plasmodium falciparum Associated with Successful Cure after Drug Therapy. | 2016 | PLoS ONE | pmid:27427762 |
| Shah SA et al. | Meibomian gland dysfunction: azithromycin and objective improvement in outcomes in posterior blepharitis. | 2016 | Clin. Experiment. Ophthalmol. | pmid:27314917 |
| Davido B et al. | Why should 1 gram of ceftriaxone monotherapy be considered as a therapeutic option in gonococcal sexually transmitted diseases? | 2016 | Clin. Microbiol. Infect. | pmid:27404364 |
| Belkacem A et al. | Molecular epidemiology and mechanisms of resistance of azithromycin-resistant Neisseria gonorrhoeae isolated in France during 2013-14. | 2016 | J. Antimicrob. Chemother. | pmid:27301565 |
| Malhotra S et al. | Prevalence of Trachoma in Car-Nicobar Island, India after Three Annual Rounds of Mass Drug Administration with Azithromycin. | 2016 | PLoS ONE | pmid:27391274 |
| Marks M | Yaws: towards the WHO eradication target. | 2016 | Trans. R. Soc. Trop. Med. Hyg. | pmid:27268712 |
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| Katanami Y et al. | Six Cases of Paratyphoid Fever Due to Salmonella Paratyphi A in Travelers Returning from Myanmar Between July 2014 and August 2015. | 2016 | Am. J. Trop. Med. Hyg. | pmid:27352874 |
| Mertens TC et al. | Azithromycin differentially affects the IL-13-induced expression profile in human bronchial epithelial cells. | 2016 | Pulm Pharmacol Ther | pmid:27246785 |
| Geisler WM et al. | Azithromycin versus Doxycycline for Chlamydia. | 2016 | N. Engl. J. Med. | pmid:27144856 |
| Dunn AL et al. | Naegleria fowleri That Induces Primary Amoebic Meningoencephalitis: Rapid Diagnosis and Rare Case of Survival in a 12-Year-Old Caucasian Girl. | 2016 | Lab Med | pmid:26984830 |
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| Vermeersch K et al. | The Belgian trial with azithromycin for acute COPD exacerbations requiring hospitalization: an investigator-initiated study protocol for a multicenter, randomized, double-blind, placebo-controlled trial. | 2016 | Int J Chron Obstruct Pulmon Dis | pmid:27099485 |
| Levy V et al. | A Case of Persistent and Possibly Treatment Resistant Pharyngeal Gonorrhea. | 2016 | Sex Transm Dis | pmid:26967304 |
| Guo Y et al. | Chlamydiaphage φCPG1 Capsid Protein Vp1 Inhibits Chlamydia trachomatis Growth via the Mitogen-Activated Protein Kinase Pathway. | 2016 | Viruses | pmid:27089359 |
| Gülses A and Ayna M | Re: Comparison of Azithromycin and Amoxicillin Before Dental Implant Placement: An Exploratory Study of Bioavailability and Resolution of Postoperative Inflammation. | 2016 | J. Periodontol. | pmid:26962889 |
| Hu J et al. | Streptococcus pneumoniae and Haemophilus influenzae type b carriage in Chinese children aged 12-18 months in Shanghai, China: a cross-sectional study. | 2016 | BMC Infect. Dis. | pmid:27080523 |
| McClure KS and Cameron ST | An audit of expedited treatment for uncomplicated Chlamydia trachomatis index cases at the community pharmacy. | 2016 | Int J STD AIDS | pmid:26945591 |
| Liang JY et al. | Azithromycin-resistant Neisseria gonorrhoeae isolates in Guangzhou, China (2009-2013): coevolution with decreased susceptibilities to ceftriaxone and genetic characteristics. | 2016 | BMC Infect. Dis. | pmid:27080231 |
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| Moore BR et al. | Safety, tolerability and pharmacokinetic properties of coadministered azithromycin and piperaquine in pregnant Papua New Guinean women. | 2016 | Br J Clin Pharmacol | pmid:26889763 |
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| Jentsch HF et al. | Nonsurgical therapy of chronic periodontitis with adjunctive systemic azithromycin or amoxicillin/metronidazole. | 2016 | Clin Oral Investig | pmid:26685849 |
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| Mukai S et al. | Macrolides sensitize EGFR-TKI-induced non-apoptotic cell death via blocking autophagy flux in pancreatic cancer cell lines. | 2016 | Int. J. Oncol. | pmid:26718641 |
| Miyagawa T et al. | Azithromycin recovers reductions in barrier function in human gingival epithelial cells stimulated with tumor necrosis factor-α. | 2016 | Arch. Oral Biol. | pmid:26655749 |
| Smith DJ et al. | Pseudomonas aeruginosa antibiotic resistance in Australian cystic fibrosis centres. | 2016 | Respirology | pmid:26711802 |
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| Lee SJ et al. | Maternal azithromycin administration eradicates intra-amniotic Ureaplasma infection: The first human case report. | 2016 | J Obstet Gynaecol | pmid:26634623 |
| Martin I et al. | Decline in Decreased Cephalosporin Susceptibility and Increase in Azithromycin Resistance in Neisseria gonorrhoeae, Canada. | 2016 | Emerging Infect. Dis. | pmid:26689114 |
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| Yang CJ et al. | Comparison of serological responses to single-dose azithromycin (2 g) versus benzathine penicillin G in the treatment of early syphilis in HIV-infected patients in an area of low prevalence of macrolide-resistant Treponema pallidum infection. | 2016 | J. Antimicrob. Chemother. | pmid:26604241 |
| Chisholm SA et al. | An outbreak of high-level azithromycin resistant Neisseria gonorrhoeae in England. | 2016 | Sex Transm Infect | pmid:26601852 |
| Hood D et al. | A new model for non-typeable Haemophilus influenzae middle ear infection in the Junbo mutant mouse. | 2016 | Dis Model Mech | pmid:26611891 |
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| Luo Q et al. | Surface plasmon resonance sensor for antibiotics detection based on photo-initiated polymerization molecularly imprinted array. | 2016 | Talanta | pmid:27769483 |
| Unger HW et al. | Azithromycin-containing intermittent preventive treatment in pregnancy affects gestational weight gain, an important predictor of birthweight in Papua New Guinea - an exploratory analysis. | 2016 | Matern Child Nutr | pmid:26373537 |
| Zhang Z et al. | Clinical effect of azithromycin as an adjunct to non-surgical treatment of chronic periodontitis: a meta-analysis of randomized controlled clinical trials. | 2016 | J. Periodont. Res. | pmid:26362529 |
| Chang Y et al. | Factors Influencing the HPLC Determination for Related Substances of Azithromycin. | 2016 | J Chromatogr Sci | pmid:26324196 |
| Shunmugaperumal T and Kaur V | In Vitro Anti-inflammatory and Antimicrobial Activities of Azithromycin After Loaded in Chitosan- and Tween 20-Based Oil-in-Water Macroemulsion for Acne Management. | 2016 | AAPS PharmSciTech | pmid:26314246 |
| VÃchová B et al. | First molecular identification of Babesia gibsoni in dogs from Slovakia, central Europe. | 2016 | Ticks Tick Borne Dis | pmid:26304014 |
| Bhargava A et al. | Scrub typhus in Uttarakhand & adjoining Uttar Pradesh: Seasonality, clinical presentations & predictors of mortality. | 2016 | Indian J. Med. Res. | pmid:28474627 |
| Fegan D et al. | Tropical leg ulcers in children: more than yaws. | 2016 | Trop Doct | pmid:26289420 |
| Caspi M et al. | A flow cytometry-based reporter assay identifies macrolide antibiotics as nonsense mutation read-through agents. | 2016 | J. Mol. Med. | pmid:26620677 |
| Retallack H et al. | Zika virus cell tropism in the developing human brain and inhibition by azithromycin. | 2016 | Proc. Natl. Acad. Sci. U.S.A. | pmid:27911847 |
| Brittain C et al. | Gentamicin versus ceftriaxone for the treatment of gonorrhoea (G-TOG trial): study protocol for a randomised trial. | 2016 | Trials | pmid:27881151 |
| Libois A and De Wit S | Which empiric syndromic treatment for urethritis? | 2016 | Int J STD AIDS | pmid:27794143 |
| Gaudreau C et al. | Shigella flexneri with Ciprofloxacin Resistance and Reduced Azithromycin Susceptibility, Canada, 2015. | 2016 | Emerging Infect. Dis. | pmid:27767915 |
| Narita M et al. | Antimicrobial Susceptibility of Microorganisms Isolated from Periapical Periodontitis Lesions. | 2016 | Bull. Tokyo Dent. Coll. | pmid:27665691 |
| Dombrowski JC and Batteiger BE | Reconsidering the Use of Azithromycin for Chlamydial Urethritis. | 2016 | Sex Transm Dis | pmid:27626187 |
| Yadav H et al. | Azithromycin for the Treatment of Obliterative Bronchiolitis after Hematopoietic Stem Cell Transplantation: A Systematic Review and Meta-Analysis. | 2016 | Biol. Blood Marrow Transplant. | pmid:27575542 |
| Lemieux JE et al. | A global map of genetic diversity in Babesia microti reveals strong population structure and identifies variants associated with clinical relapse. | 2016 | Nat Microbiol | pmid:27572973 |
| Narayanasamy DK et al. | Clinico - Laboratory Profile of Scrub Typhus - An Emerging Rickettsiosis in India. | 2016 | Indian J Pediatr | pmid:27352842 |
| Keenan JD et al. | Nasopharyngeal Pneumococcal Serotypes Before and After Mass Azithromycin Distributions for Trachoma. | 2016 | J Pediatric Infect Dis Soc | pmid:27199475 |