Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Harris JA et al. | Safety and efficacy of azithromycin in the treatment of community-acquired pneumonia in children. | 1998 | Pediatr. Infect. Dis. J. | pmid:9802626 |
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| Saegeman V et al. | Management of macrolide-resistant Mycoplasma pneumoniae infection. | 2012 | Pediatr. Infect. Dis. J. | pmid:22668803 |
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| Arguedas A et al. | A randomized, multicenter, double blind, double dummy trial of single dose azithromycin versus high dose amoxicillin for treatment of uncomplicated acute otitis media. | 2005 | Pediatr. Infect. Dis. J. | pmid:15702045 |
| Jacobs RF et al. | Pharmacokinetics of intravenously administered azithromycin in pediatric patients. | 2005 | Pediatr. Infect. Dis. J. | pmid:15665708 |
| Powers JL et al. | Comparison of the palatability of the oral suspension of cefdinir vs. amoxicillin/clavulanate potassium, cefprozil and azithromycin in pediatric patients. | 2000 | Pediatr. Infect. Dis. J. | pmid:11144401 |
| Tramper-Stranders GA et al. | Maintenance azithromycin treatment in pediatric patients with cystic fibrosis: long-term outcomes related to macrolide resistance and pulmonary function. | 2007 | Pediatr. Infect. Dis. J. | pmid:17195698 |
| Esposito S et al. | Role of atypical bacteria and azithromycin therapy for children with recurrent respiratory tract infections. | 2005 | Pediatr. Infect. Dis. J. | pmid:15876944 |
| Gomperts BN and White LK | Gonococcal hand abscess. | 2000 | Pediatr. Infect. Dis. J. | pmid:10917235 |
| Glanternik JR et al. | A Cluster of Cases of Babesia microti Among Neonates Traced to a Single Unit of Donor Blood. | 2018 | Pediatr. Infect. Dis. J. | pmid:28945680 |
| Adegbola RA et al. | Effect of azithromycin on pharyngeal microflora. | 1995 | Pediatr. Infect. Dis. J. | pmid:7603826 |
| Jain SK et al. | Antimicrobial-resistant Shigella sonnei: limited antimicrobial treatment options for children and challenges of interpreting in vitro azithromycin susceptibility. | 2005 | Pediatr. Infect. Dis. J. | pmid:15933557 |
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| Bowden FJ et al. | Donovanosis causing cervical lymphadenopathy in a five-month-old boy. | 2000 | Pediatr. Infect. Dis. J. | pmid:10694010 |
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| Bass JW et al. | Prospective randomized double blind placebo-controlled evaluation of azithromycin for treatment of cat-scratch disease. | 1998 | Pediatr. Infect. Dis. J. | pmid:9655532 |
| Klein JO | History of macrolide use in pediatrics. | 1997 | Pediatr. Infect. Dis. J. | pmid:9109154 |
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| Nguyen D et al. | Clinical response to azithromycin in cystic fibrosis correlates with in vitro effects on Pseudomonas aeruginosa phenotypes. | 2007 | Pediatr. Pulmonol. | pmid:17469154 |
| Kogan R et al. | Comparative randomized trial of azithromycin versus erythromycin and amoxicillin for treatment of community-acquired pneumonia in children. | 2003 | Pediatr. Pulmonol. | pmid:12526069 |
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| Wilms EB et al. | Azithromycin maintenance therapy in patients with cystic fibrosis: a dose advice based on a review of pharmacokinetics, efficacy, and side effects. | 2012 | Pediatr. Pulmonol. | pmid:22684985 |
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| ElMallah MK et al. | Plastic bronchitis: resolution after heart transplantation. | 2011 | Pediatr. Pulmonol. | pmid:21465672 |
| Ballard HO et al. | Use of azithromycin for the prevention of bronchopulmonary dysplasia in preterm infants: a randomized, double-blind, placebo controlled trial. | 2011 | Pediatr. Pulmonol. | pmid:20963840 |
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| Cohen DA et al. | A school-based Chlamydia control program using DNA amplification technology. | 1998 | Pediatrics | pmid:9417165 |
| Amer A and Fischer H | Azithromycin does not cure pityriasis rosea. | 2006 | Pediatrics | pmid:16651327 |
| Clavier A and Hupert J | Azithromycin for pityriasis. | 2006 | Pediatrics | pmid:17079605 |
| Fox JW et al. | Recurrent expressive aphasia as a presentation of cat-scratch encephalopathy. | 2007 | Pediatrics | pmid:17332191 |