Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Ito N and Kudo S | [Case of polycystic lung disease with mixed infections due to Aspergillus and Mycobacterium fortuitum successfully treated by AZM]. | 2002 | Jpn J Antibiot | pmid:12664928 |
| Gibb AM et al. | Should we offer antibiotic prophylaxis post sexual assault? | 2003 | Int J STD AIDS | pmid:12662387 |
| Muñoz B et al. | Antibiotic dosage in trachoma control programs: height as a surrogate for weight in children. | 2003 | Invest. Ophthalmol. Vis. Sci. | pmid:12657580 |
| Danesi R et al. | Comparative distribution of azithromycin in lung tissue of patients given oral daily doses of 500 and 1000 mg. | 2003 | J. Antimicrob. Chemother. | pmid:12654753 |
| Carryn S et al. | Activity of beta-lactams (ampicillin, meropenem), gentamicin, azithromycin and moxifloxacin against intracellular Listeria monocytogenes in a 24 h THP-1 human macrophage model. | 2003 | J. Antimicrob. Chemother. | pmid:12654747 |
| Katusic D et al. | Azithromycin vs doxycycline in the treatment of inclusion conjunctivitis. | 2003 | Am. J. Ophthalmol. | pmid:12654359 |
| Anagnostopoulos GK et al. | Omeprazole plus azithromycin and either amoxicillin or tinidazole for eradication of Helicobacter pylori infection. | 2003 | J. Clin. Gastroenterol. | pmid:12642739 |
| Cercek B et al. | Effect of short-term treatment with azithromycin on recurrent ischaemic events in patients with acute coronary syndrome in the Azithromycin in Acute Coronary Syndrome (AZACS) trial: a randomised controlled trial. | 2003 | Lancet | pmid:12642046 |
| Tajima T et al. | [Discussions on PRSP and BLNAR]. | 2001 | Jpn J Antibiot | pmid:12638161 |
| Bevan CD et al. | Efficacy and safety of azithromycin as monotherapy or combined with metronidazole compared with two standard multidrug regimens for the treatment of acute pelvic inflammatory disease. | 2003 Jan-Feb | J. Int. Med. Res. | pmid:12635534 |
| Ramsey PS et al. | Maternal and transplacental pharmacokinetics of azithromycin. | 2003 | Am. J. Obstet. Gynecol. | pmid:12634646 |
| Kuvin JT et al. | Effect of short-term antibiotic treatment on Chlamydia pneumoniae and peripheral endothelial function. | 2003 | Am. J. Cardiol. | pmid:12633811 |
| Amsden GW et al. | Efficacy and safety of azithromycin vs levofloxacin in the outpatient treatment of acute bacterial exacerbations of chronic bronchitis. | 2003 | Chest | pmid:12628877 |
| Salcedo Posadas A et al. | [Complementary therapies in cystic fibrosis: evidence of therapeutic benefits and treatment recommendations]. | 2003 | An Pediatr (Barc) | pmid:12628117 |
| Basilion EV et al. | Height as a proxy for weight in determining azithromycin treatment for paediatric trachoma. | 2002 Nov-Dec | Trans. R. Soc. Trop. Med. Hyg. | pmid:12625152 |
| Hanada H et al. | Infection of human fibroblast-like synovial cells with Chlamydia trachomatis results in persistent infection and interleukin-6 production. | 2003 | Microb. Pathog. | pmid:12623273 |
| Schlünzen F et al. | Structural basis for the antibiotic activity of ketolides and azalides. | 2003 | Structure | pmid:12623020 |
| [Uncomplicated community-acquired pneumonia. Under control in 3 treatment days]. | 2003 | MMW Fortschr Med | pmid:12619240 | |
| Al-Belasy FA and Hairam AR | The efficacy of azithromycin in the treatment of acute infraorbital space infection. | 2003 | J. Oral Maxillofac. Surg. | pmid:12618970 |
| Scheinfeld NS et al. | Macrolides in dermatology. | 2003 Jan-Feb | Clin. Dermatol. | pmid:12609587 |
| Mesa FL et al. | Antibiotic treatment of incipient drug-induced gingival overgrowth in adult renal transplant patients. | 2003 | J. Periodont. Res. | pmid:12608908 |
| Aznabaev MT et al. | [Use of cycloferon in a combined treatment of chlamydial conjunctivitis]. | 2003 Jan-Feb | Vestn Oftalmol | pmid:12608044 |
| Schiedler V et al. | Pattern of antibiotic use in a trachoma-endemic region of Nepal: implications for mass azithromycin distribution. | 2003 | Ophthalmic Epidemiol | pmid:12607157 |
| Roblin PM et al. | In vitro activities of rifamycin derivatives ABI-1648 (Rifalazil, KRM-1648), ABI-1657, and ABI-1131 against Chlamydia trachomatis and recent clinical isolates of Chlamydia pneumoniae. | 2003 | Antimicrob. Agents Chemother. | pmid:12604555 |
| Seral C et al. | Influence of P-glycoprotein inhibitors on accumulation of macrolides in J774 murine macrophages. | 2003 | Antimicrob. Agents Chemother. | pmid:12604540 |
| Peric M et al. | Effects of an efflux mechanism and ribosomal mutations on macrolide susceptibility of Haemophilus influenzae clinical isolates. | 2003 | Antimicrob. Agents Chemother. | pmid:12604536 |
| Coke RL et al. | Pharmacokinetics and tissue concentrations of azithromycin in ball pythons (Python regius). | 2003 | Am. J. Vet. Res. | pmid:12602593 |
| Khedr A and Sheha M | Quantitative thin-layer chromatographic method of analysis of azithromycin in pure and capsule forms. | 2003 | J Chromatogr Sci | pmid:12597590 |
| Dzelalija B et al. | Randomized trial of azithromycin in the prophylaxis of Mediterranean spotted fever. | 2002 | Acta Med Croatica | pmid:12596623 |
| Kwun WH et al. | Effect of azithromycin in the treartment of cyclosporine-induced gingival hyperplasia in renal transplant recipients. | 2003 | Transplant. Proc. | pmid:12591416 |
| Dakdouki GK et al. | Azithromycin-induced rash in infectious mononucleosis. | 2002 | Scand. J. Infect. Dis. | pmid:12587634 |
| Esteban J et al. | A comparison between disk diffusion and microdilution for susceptibility testing of Mycobacterium fortuitum complex. | 2002 | J Chemother | pmid:12583544 |
| Mehta CL | Arcanobacterium haemolyticum. | 2003 | J. Am. Acad. Dermatol. | pmid:12582410 |
| Tanyuksel M et al. | Determination of intracellular efficacies of azithromycin against Leishmania major infection in human neutrophils in vitro. | 2003 | Cell Biochem. Funct. | pmid:12579528 |
| Tateda K et al. | [MIC, sub-MIC of macrolide resistant bacteria--special reference to their quorum-sensing system]. | 2001 | Jpn J Antibiot | pmid:12575433 |
| Pechère JC | Azithromycin reduces the production of virulence factors in Pseudomonas aeruginosa by inhibiting quorum sensing. | 2001 | Jpn J Antibiot | pmid:12575427 |
| Kato T et al. | [Effect of azithromycin on cytokine production in human bronchial epithelial cell line, BEAS-2B]. | 2001 | Jpn J Antibiot | pmid:12575426 |
| Ikegaya S et al. | [Effect of azithromycin on cytokine production by THP-1 cells]. | 2001 | Jpn J Antibiot | pmid:12575425 |
| Nagata T et al. | [Two cases successfully treated with long-term administration of low-dosage azithromycin]. | 2001 | Jpn J Antibiot | pmid:12575407 |
| Dai G et al. | [Researching some sensitivity factor of bioassay method on the antibiotics pharmacokinetics]. | 2002 | Hunan Yi Ke Da Xue Xue Bao | pmid:12575254 |
| Woods GL et al. | Multisite reproducibility of results obtained by two broth dilution methods for susceptibility testing of Mycobacterium avium complex. | 2003 | J. Clin. Microbiol. | pmid:12574258 |
| Higa F and Saito A | [Clinical safety of azithromycin]. | 2000 | Jpn J Antibiot | pmid:12572096 |
| Sasaki J | [Azithromycin in dentistry and oral surgery]. | 2000 | Jpn J Antibiot | pmid:12572095 |
| Arata J | [Azithromycin in the field of dermatology]. | 2000 | Jpn J Antibiot | pmid:12572094 |
| Naoya M | [The clinical study of azithromycin in otolaryngologic infection]. | 2000 | Jpn J Antibiot | pmid:12572093 |
| Sunakawa K | [Summary of the clinical studies with azithromycin in the pediatric fields]. | 2000 | Jpn J Antibiot | pmid:12572092 |
| Nakayama I | [Clinical studies of azithromycin, a new macrolide antibiotic, for infections in the field of surgery]. | 2000 | Jpn J Antibiot | pmid:12572091 |
| Oizumi K | [Clinical evaluation of azithromycin for respiratory infectious diseases]. | 2000 | Jpn J Antibiot | pmid:12572090 |
| Enogaki K | [Transport to an infected site of azithromycin by phagocyte cells]. | 2000 | Jpn J Antibiot | pmid:12572089 |
| Shiba K | [Pharmacokinetics and tissue distribution of azithromycin in humans]. | 2000 | Jpn J Antibiot | pmid:12572088 |
| Miyazaki S and Yamaguchi K | [In vitro and in vivo antibacterial activities of azithromycin]. | 2000 | Jpn J Antibiot | pmid:12572087 |
| Debremaeker D et al. | Analysis of unknown compounds in azithromycin bulk samples with liquid chromatography coupled to ion trap mass spectrometry. | 2003 | Rapid Commun. Mass Spectrom. | pmid:12569445 |
| OÄŸuz F et al. | Etiology of acute otitis media in childhood and evaluation of two different protocols of antibiotic therapy: 10 days cefaclor vs. 3 days azitromycin. | 2003 | Int. J. Pediatr. Otorhinolaryngol. | pmid:12560149 |
| Southern KW and Smyth RL | Design of clinical trials in cystic fibrosis. | 2003 | Lancet | pmid:12559892 |
| Rekart ML et al. | Targeted mass treatment for syphilis with oral azithromycin. | 2003 | Lancet | pmid:12559870 |
| Sanchez JL et al. | An outbreak of pneumococcal pneumonia among military personnel at high risk: control by low-dose azithromycin postexposure chemoprophylaxis. | 2003 | Mil Med | pmid:12546236 |
| Knuf M et al. | [Lymphadenitis colli due to non-tuberculous mycobacteria (NTM): a case-series and review of the literature]. | 2003 Jan-Feb | Klin Padiatr | pmid:12545419 |
| Niv Y and Abuksis G | Survey of the opinions, knowledge and practices of surgeons and internists regarding Helicobacter pylori test-and-treat policy. | 2003 | J. Clin. Gastroenterol. | pmid:12544197 |
| Gaynor BD et al. | Community treatment with azithromycin for trachoma is not associated with antibiotic resistance in Streptococcus pneumoniae at 1 year. | 2003 | Br J Ophthalmol | pmid:12543738 |
| Javaloy J et al. | Follicular conjunctivitis caused by Chlamydia trachomatis in an infant Saharan population: molecular and clinical diagnosis. | 2003 | Br J Ophthalmol | pmid:12543737 |
| Hoffman HL et al. | Influence of macrolide susceptibility on efficacies of clarithromycin and azithromycin against Streptococcus pneumoniae in a murine lung infection model. | 2003 | Antimicrob. Agents Chemother. | pmid:12543686 |
| Goswick SM and Brenner GM | Activities of azithromycin and amphotericin B against Naegleria fowleri in vitro and in a mouse model of primary amebic meningoencephalitis. | 2003 | Antimicrob. Agents Chemother. | pmid:12543653 |
| [Azithromycin for pediatric indications. Brief therapy is ideal for children]. | 2002 | MMW Fortschr Med | pmid:12532527 | |
| [Antibiotics in routine practice. With proper selection rapid success]. | 2002 | MMW Fortschr Med | pmid:12532526 | |
| Ovetchkine P and Cohen R | Shortened course of antibacterial therapy for acute otitis media. | 2003 | Paediatr Drugs | pmid:12529165 |
| Ewald DP et al. | An evaluation of a SAFE-style trachoma control program in Central Australia. | 2003 | Med. J. Aust. | pmid:12526724 |
| Schultz KD and Oermann CM | Treatment of cast bronchitis with low-dose oral azithromycin. | 2003 | Pediatr. Pulmonol. | pmid:12526076 |
| Kogan R et al. | Comparative randomized trial of azithromycin versus erythromycin and amoxicillin for treatment of community-acquired pneumonia in children. | 2003 | Pediatr. Pulmonol. | pmid:12526069 |
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| Schillinger JA et al. | Patient-delivered partner treatment with azithromycin to prevent repeated Chlamydia trachomatis infection among women: a randomized, controlled trial. | 2003 | Sex Transm Dis | pmid:12514443 |
| Allam AF and Shehab AY | Efficacy of azithromycin, praziquantel and mirazid in treatment of cryptosporidiosis in school children. | 2002 | J Egypt Soc Parasitol | pmid:12512828 |
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| Khan WA et al. | Comparison of single-dose azithromycin and 12-dose, 3-day erythromycin for childhood cholera: a randomised, double-blind trial. | 2002 | Lancet | pmid:12480424 |
| Hauke W et al. | Esberitox N as supportive therapy when providing standard antibiotic treatment in subjects with a severe bacterial infection (acute exacerbation of chronic bronchitis). A multicentric, prospective, double-blind, placebo-controlled study. | 2002 | Chemotherapy | pmid:12476043 |
| Ranque S et al. | Triangular test applied to the clinical trial of azithromycin against relapses in Plasmodium vivax infections. | 2002 | Malar. J. | pmid:12473182 |
| Chiu LM et al. | Pharmacokinetics of intravenous azithromycin and ceftriaxone when administered alone and concurrently to healthy volunteers. | 2002 | J. Antimicrob. Chemother. | pmid:12461037 |
| Di Paolo A et al. | Pharmacokinetics of azithromycin in lung tissue, bronchial washing, and plasma in patients given multiple oral doses of 500 and 1000 mg daily. | 2002 | Pharmacol. Res. | pmid:12457629 |
| Tyteca D et al. | Azithromycin, a lysosomotropic antibiotic, has distinct effects on fluid-phase and receptor-mediated endocytosis, but does not impair phagocytosis in J774 macrophages. | 2002 | Exp. Cell Res. | pmid:12441132 |
| Pastor E et al. | [Macrolide consumption according to geographic areas in the province of Valladolid]. | 2002 | Enferm. Infecc. Microbiol. Clin. | pmid:12433351 |
| Kamau FN et al. | Isocratic liquid chromatographic method for the analysis of azithromycin and its structurally related substances in bulk samples. | 2002 | J Chromatogr Sci | pmid:12433117 |
| Kadappu KK et al. | Azithromycin as treatment for cryptosporidiosis in human immunodeficiency virus disease. | 2002 Jul-Sep | J Postgrad Med | pmid:12432190 |
| Hall IH et al. | Disposition and intracellular activity of azithromycin in human THP-1 acute monocytes. | 2002 | Int. J. Antimicrob. Agents | pmid:12431870 |
| Maraspin V et al. | Development of erythema migrans in spite of treatment with antibiotics after a tick bite. | 2002 | Wien. Klin. Wochenschr. | pmid:12422612 |
| Arnez M et al. | Solitary erythema migrans in children: comparison of treatment with azithromycin and phenoxymethylpenicillin. | 2002 | Wien. Klin. Wochenschr. | pmid:12422590 |
| Tambiah J and Powell JT | Chlamydia pneumoniae antigens facilitate experimental aortic dilatation: prevention with azithromycin. | 2002 | J. Vasc. Surg. | pmid:12422113 |
| Skerk V et al. | Comparative analysis of azithromycin and clarithromycin efficacy and tolerability in the treatment of chronic prostatitis caused by Chlamydia trachomatis. | 2002 | J Chemother | pmid:12420857 |
| Woolard S and Kenkel D | Heading off antibiotic resistance. | 2001 | Adv Nurse Pract | pmid:12420432 |
| Neumann FJ | Chlamydia pneumoniae-atherosclerosis link: a sound concept in search for clinical relevance. | 2002 | Circulation | pmid:12417534 |
| Krolewiecki A et al. | Activity of azithromycin against Leishmania major in vitro and in vivo. | 2002 | Am. J. Trop. Med. Hyg. | pmid:12408666 |
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| Shor A | Atherosclerosis: lipid infiltration or Chlamydia pneumoniae infection? | 2002 | Circulation | pmid:12403680 |
| Mileusnic D et al. | Pathological case of the month: sudden death in a child as a result of pancreatitis during valproic acid therapy. | 2002 Sep-Oct | Pediatr Pathol Mol Med | pmid:12396903 |
| Chandrupatla S et al. | Azithromycin-induced intrahepatic cholestasis. | 2002 | Dig. Dis. Sci. | pmid:12395890 |
| Brook I | Antibacterial therapy for acute group a streptococcal pharyngotonsillitis: short-course versus traditional 10-day oral regimens. | 2002 | Paediatr Drugs | pmid:12390046 |
| Sullivan B et al. | Comparison of azithromycin and clarithromycin in triple therapy regimens for the eradication of Helicobacter pylori. | 2002 | Am. J. Gastroenterol. | pmid:12385435 |
| Ohara T et al. | Effects of azithromycin on shiga toxin production by Escherichia coli and subsequent host inflammatory response. | 2002 | Antimicrob. Agents Chemother. | pmid:12384353 |
| Equi A et al. | Long term azithromycin in children with cystic fibrosis: a randomised, placebo-controlled crossover trial. | 2002 | Lancet | pmid:12383667 |
| Itoh M et al. | [A case of immotile-dyskinetic cilia syndrome responding to clenbuterol hydrochloride and azithromycin]. | 2002 | Nihon Kokyuki Gakkai Zasshi | pmid:12382429 |