Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Azithramycine
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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pmid:21439162 | ||||
Zhou QT et al. | How Much Surface Coating of Hydrophobic Azithromycin Is Sufficient to Prevent Moisture-Induced Decrease in Aerosolisation of Hygroscopic Amorphous Colistin Powder? | 2016 | AAPS J | pmid:27255350 |
Gandhi SV et al. | Considerations for a Pediatric Biopharmaceutics Classification System (BCS): application to five drugs. | 2014 | AAPS PharmSciTech | pmid:24557773 |
Shunmugaperumal T and Kaur V | In Vitro Anti-inflammatory and Antimicrobial Activities of Azithromycin After Loaded in Chitosan- and Tween 20-Based Oil-in-Water Macroemulsion for Acne Management. | 2016 | AAPS PharmSciTech | pmid:26314246 |
Wei W et al. | MPEG-PCL Copolymeric Micelles for Encapsulation of Azithromycin. | 2018 | AAPS PharmSciTech | pmid:29675667 |
Wendel TD | 1-day azithromycin was as effective as 7-day doxycycline for nongonococcal urethritis syndrome in men. | 1996 Nov-Dec | ACP J. Club | pmid:8912627 |
Russo V et al. | Azithromycin-induced QT prolongation in elderly patient. | 2006 | Acta Biomed | pmid:16856707 |
Delmée M et al. | In vitro susceptibilities of 180 clinical isolates of Haemophilus influenzae to ampicillin, amoxycillin/clavulanate, cefaclor, cefuroxime, cefotaxime, clarithromycin, and azithromycin. | 1996 | Acta Clin Belg | pmid:8858889 |
Moi H et al. | Spontaneous Regression of Untreatable Mycoplasma genitalium Urethritis. | 2015 | Acta Derm. Venereol. | pmid:25634824 |
Cusini M | Therapy for Gonococcal and Non-gonococcal Genital Infections is a Major Problem for Clinicians. | 2015 | Acta Derm. Venereol. | pmid:25917593 |
Unemo M et al. | Five-day Azithromycin Treatment Regimen for Mycoplasma genitalium Infection Also Effectively Eradicates Chlamydia trachomatis. | 2015 | Acta Derm. Venereol. | pmid:25823977 |
Brkljacić N et al. | Stevens-Johnson syndrome as an unusual adverse effect of azithromycin. | 2006 | Acta Dermatovenerol Croat | pmid:16603101 |
Basta-Juzbasić A et al. | A dose-finding study of azithromycin in the treatment of acne vulgaris. | 2007 | Acta Dermatovenerol Croat | pmid:17868539 |
Innocenzi D et al. | Moderate acne vulgaris: efficacy, tolerance and compliance of oral azithromycin thrice weekly for. | 2008 | Acta Dermatovenerol Croat | pmid:18358103 |
Vcev A et al. | Omeprazole, azithromycin and amoxicillin or amoxicillin plus clavulanic acid in eradication of Helicobacter pylori in duodenal ulcer disease. | 1998 | Acta Med Croatica | pmid:9988898 |
Vladusić I et al. | [Long term survival after Rhodococcus equi pneumonia in a patient with human immunodeficiency virus infection in the era of highly active antiretroviral therapy: case report and review]. | 2006 | Acta Med Croatica | pmid:16933840 |
Dzelalija B et al. | Randomized trial of azithromycin in the prophylaxis of Mediterranean spotted fever. | 2002 | Acta Med Croatica | pmid:12596623 |
Hincapié JP et al. | Microbiological effects of periodontal therapy plus azithromycin in patients with diabetes: results from a randomized clinical trial. | 2014 | Acta Odontol Latinoam | pmid:25523961 |
Wirostko BM and Wirostko WJ | The possible role of systemic azithromycin for idiopathic iridocyclitis. | 2010 | Acta Ophthalmol | pmid:19891670 |