Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Airway Obstruction D000402 13 associated lipids
Stomach Ulcer D013276 75 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Hearing Loss, Sensorineural D006319 8 associated lipids
Otitis Media D010033 12 associated lipids
Carcinoma, Basal Cell D002280 6 associated lipids
Bacterial Infections D001424 21 associated lipids
Pain D010146 64 associated lipids
Per page 10 20 50 100 | Total 276

PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

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Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


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Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
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From the Centers for Disease Control and Prevention. Fluoroquinolone resistance in Neisseria gonorrhoeae, Hawaii, 1999, and decreased susceptibility to azithromycin in N. gonorrhoeae, Missouri, 1999. 2000 JAMA pmid:11183745
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McNabb J et al. Comparison of azithromycin leukocyte disposition in healthy volunteers and volunteers with AIDS. 2000 Int. J. Antimicrob. Agents pmid:11185411
Amsden GW et al. A study of the pharmacokinetics of azithromycin and nelfinavir when coadministered in healthy volunteers. 2000 J Clin Pharmacol pmid:11185676
Mamikoglu B and Mamikoglu O Irreversible sensorineural hearing loss as a result of azithromycin ototoxicity. A case report. 2001 Ann. Otol. Rhinol. Laryngol. pmid:11201801
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Bogdanov MB and Chernen'kaia TV [Microbiological evaluation of antibiotics for empirical therapy of community-acquired infections of the lower respiratory tract]. 2000 Antibiot. Khimioter. pmid:11212394
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Solomon AW et al. Pilot study of the use of community volunteers to distribute azithromycin for trachoma control in Ghana. 2001 Bull. World Health Organ. pmid:11217675
Bregani ER et al. Azithromycin in the treatment of Plasmodium falciparum gametocytes. Preliminary observation. 2000 Panminerva Med pmid:11218625
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Cascaval RI and Lancaster DJ Hypersensitivity syndrome associated with azithromycin. 2001 Am. J. Med. pmid:11247598
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Lietman T and Fry A Can we eliminate trachoma? 2001 Br J Ophthalmol pmid:11264123
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Butler T et al. In vitro effects of azithromycin on Salmonella typhi: early inhibition by concentrations less than the MIC and reduction of MIC by alkaline pH and small inocula. 2001 J. Antimicrob. Chemother. pmid:11266420
Bharat V and Mohanty B Bleeding complication during coumarin therapy due to amiodarone and azithromycin. 2000 J Assoc Physicians India pmid:11273517
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Tateda K et al. Azithromycin inhibits quorum sensing in Pseudomonas aeruginosa. 2001 Antimicrob. Agents Chemother. pmid:11353657
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Clearance to market azithromycin as prevention for a common OI in advanced AIDS. 1996 AIDS Patient Care STDS pmid:11361535
Prophylactic antibiotic receives speedy FDA approval to reduce MAC disease in advanced HIV. 1996 AIDS Patient Care STDS pmid:11361569
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