Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Airway Obstruction D000402 13 associated lipids
Stomach Ulcer D013276 75 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Hearing Loss, Sensorineural D006319 8 associated lipids
Otitis Media D010033 12 associated lipids
Carcinoma, Basal Cell D002280 6 associated lipids
Bacterial Infections D001424 21 associated lipids
Pain D010146 64 associated lipids
Per page 10 20 50 100 | Total 276

PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Ribeiro M et al. Azithromycin treatment is able to control the infection by two genotypes of Toxoplasma gondii in human trophoblast BeWo cells. 2017 Exp. Parasitol. pmid:28803905
Benn K et al. Bradycardia and Hypothermia Complicating Azithromycin Treatment. 2017 Am J Case Rep pmid:28798290
Bergeron A et al. Effect of Azithromycin on Airflow Decline-Free Survival After Allogeneic Hematopoietic Stem Cell Transplant: The ALLOZITHRO Randomized Clinical Trial. 2017 JAMA pmid:28787506
Hoogewoud F et al. Prognostic Factors in Syphilitic Uveitis. 2017 Ophthalmology pmid:28779905
Bloch EM et al. Antibiotic Resistance in Young Children in Kilosa District, Tanzania 4 Years after Mass Distribution of Azithromycin for Trachoma Control. 2017 Am. J. Trop. Med. Hyg. pmid:28722638
Dolezelova E et al. Resveratrol modifies biliary secretion of cholephilic compounds in sham-operated and cholestatic rats. 2017 World J. Gastroenterol. pmid:29209109
Wang CM et al. Synthesis and Antibacterial Evaluation of a Series of 11,12-Cyclic Carbonate Azithromycin-3-O-descladinosyl-3-O-carbamoyl Glycosyl Derivatives. 2017 Molecules pmid:29207567
Rasmussen LD et al. Follicular bronchiolitis in an HIV-infected individual on combination antiretroviral therapy with low CD4+ cell count but sustained viral suppression. 2017 BMJ Case Rep pmid:29191821
Emmanuel R et al. Antimicrobial efficacy of drug blended biosynthesized colloidal gold nanoparticles from Justicia glauca against oral pathogens: A nanoantibiotic approach. 2017 Microb. Pathog. pmid:29101061
González-Beiras C et al. Yaws Osteoperiostitis Treated with Single-Dose Azithromycin. 2017 Am. J. Trop. Med. Hyg. pmid:28193743
Ivanová L et al. Estimation of amount of selected pharmaceuticals sorbed onto digested sludge from wastewater treatment plant Bratislava-Petržalka. 2017 Environ. Res. pmid:28183039
Thakur SD et al. Resistance to Ceftriaxone and Azithromycin in Neisseria gonorrhoeae Isolates From 7 Countries of South America and the Caribbean: 2010-2011. 2017 Sex Transm Dis pmid:28178114
Boggess KA et al. Risk Factors for Postcesarean Maternal Infection in a Trial of Extended-Spectrum Antibiotic Prophylaxis. 2017 Obstet Gynecol pmid:28178058
Lahra MM and Enriquez RP Australian Gonococcal Surveillance Programme, 1 July to 30 September 2016
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Sharpton R et al. Do cystic fibrosis patients on azithromycin need electrocardiogram monitoring? 2017 Pulm Pharmacol Ther pmid:28219728
Kong FY et al. Pharmacokinetics of a single 1g dose of azithromycin in rectal tissue in men. 2017 PLoS ONE pmid:28350806
Bornstein M et al. Factors Associated With Primary Care Physician Knowledge of the Recommended Regimen for Treating Gonorrhea. 2017 Sex Transm Dis pmid:27898574
Checa R et al. Efficacy, safety and tolerance of imidocarb dipropionate versus atovaquone or buparvaquone plus azithromycin used to treat sick dogs naturally infected with the Babesia microti-like piroplasm. 2017 Parasit Vectors pmid:28292316
Ishiguro N et al. Therapeutic efficacy of azithromycin, clarithromycin, minocycline and tosufloxacin against macrolide-resistant and macrolide-sensitive Mycoplasma pneumoniae pneumonia in pediatric patients. 2017 PLoS ONE pmid:28288170
Babić I et al. Therapeutic efficacy of azithromycin and acetylcysteine in chronic otitis media with effusion. 2017 Eur Arch Otorhinolaryngol pmid:27873023
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Yan M et al. Synthesis and antibacterial activity of novel 3-O-descladinosylazithromycin derivatives. 2017 Eur J Med Chem pmid:27836198
Ginouvès M et al. In Vitro Sensitivity of Cutaneous Leishmania Promastigote Isolates Circulating in French Guiana to a Set of Drugs. 2017 Am. J. Trop. Med. Hyg. pmid:28167598
Giguère S Treatment of Infections Caused by Rhodococcus equi. 2017 Vet. Clin. North Am. Equine Pract. pmid:28161038
Daimee UA et al. A 77-year-old man with fever and night sweats. 2017 Eur. J. Intern. Med. pmid:27765389
Illia R et al. Role of cervical cerclage and prolonged antibiotic therapy with azithromycin in patients with previous perinatal loss amnionitis. 2017 J. Matern. Fetal. Neonatal. Med. pmid:27094535
Massip C et al. Macrolide resistance in Legionella pneumophila: the role of LpeAB efflux pump. 2017 J. Antimicrob. Chemother. pmid:28137939
Terkelsen D et al. Multidrug-resistant infection with ceftriaxone resistance and intermediate resistance to azithromycin, Denmark, 2017. 2017 Euro Surveill. pmid:29067905
Srivastava S et al. A 'shock and awe' thioridazine and moxifloxacin combination-based regimen for pulmonary Mycobacterium avium-intracellulare complex disease. 2017 J. Antimicrob. Chemother. pmid:28922810
Srivastava S et al. Failure of the azithromycin and ethambutol combination regimen in the hollow-fibre system model of pulmonary Mycobacterium avium infection is due to acquired resistance. 2017 J. Antimicrob. Chemother. pmid:28922805
Cole MJ et al. Overall Low Extended-Spectrum Cephalosporin Resistance but high Azithromycin Resistance in Neisseria gonorrhoeae in 24 European Countries, 2015. 2017 BMC Infect. Dis. pmid:28893203
Salman S et al. Optimal Antimalarial Dose Regimens for Sulfadoxine-Pyrimethamine with or without Azithromycin in Pregnancy Based on Population Pharmacokinetic Modeling. 2017 Antimicrob. Agents Chemother. pmid:28242669
Mathew A et al. Antimicrobial and Immunomodulatory Surface-Functionalized Electrospun Membranes for Bone Regeneration. 2017 Adv Healthc Mater pmid:28240815
Teng F et al. In vitro characterization of pH-sensitive azithromycin-loaded methoxy poly (ethylene glycol)-block-poly (aspartic acid-graft-imidazole) micelles. 2017 J Colloid Interface Sci pmid:28209540
Koop AH et al. 56-Year-Old Woman With Cough and Fatigue for 1 Week. 2017 Mayo Clin. Proc. pmid:28110893
Diniz LM et al. Bacillary angiomatosis with bone invasion. 2016 Nov-Dec An Bras Dermatol pmid:28099606
Akoglu G et al. Erlotinib-induced purpuric papulopustular eruption treated with pulsed azithromycin. 2016 May-Jun Indian J Pharmacol pmid:27298507
Latif SA et al. Azithromycin buccal patch in treatment of chronic periodontitis. 2016 Mar-Apr Indian J Pharmacol pmid:27127325
Oliveira IS et al. Evaluation of the improvement of quality of life with Azithromycin in the treatment of eosinophilic nasal polyposis. 2016 Mar-Apr Braz J Otorhinolaryngol pmid:26601998
Chatterjee S et al. Azithromycin susceptibility among clinical isolates of Salmonella: Interfacing guidelines with routine practices. 2016 Jul-Sep Indian J Med Microbiol pmid:27514976
Hazra A Author Reply. 2016 Jan-Feb Indian J Pharmacol pmid:26997735
Das S and Mohanty M Comparative evaluation of 2 g single dose versus conventional dose azithromycin in uncomplicated skin and skin structure infections. 2016 Jan-Feb Indian J Pharmacol pmid:26997734
Das A et al. Azithromycin induced bullous fixed drug eruption. 2016 Jan-Feb Indian J Pharmacol pmid:26997729
Yazdanbakhsh AR et al. Reduction of non-Betalactam Antibiotics COD by Combined Coagulation and Advanced Oxidation Processes. 2016 Water Environ. Res. pmid:28661328
Liao YS et al. Azithromycin-Nonsusceptible Shigella flexneri 3a in Men Who Have Sex with Men, Taiwan, 2015-2016. 2016 Emerging Infect. Dis. pmid:28098533
Espadas D et al. Lack of effect of azithromycin on QT interval in children: a cohort study. 2016 Arch. Dis. Child. pmid:27515186
Serdar Kutuk M et al. Relationship between maternal c-reactive protein level and neonatal outcome in patients with preterm premature rupture of membranes treated with Ampicillin and Azithromycin. 2016 J Obstet Gynaecol pmid:27825282
Ervin AM et al. Surveillance and Azithromycin Treatment for Newcomers and Travelers Evaluation (ASANTE) Trial: Design and Baseline Characteristics. 2016 Ophthalmic Epidemiol pmid:27820670
Weintraub A et al. In-vitro activity of solithromycin against anaerobic bacteria from the normal intestinal microbiota. 2016 Anaerobe pmid:27725229
Berkowitz ST et al. Resolution of spontaneous hemoabdomen secondary to peliosis hepatis following surgery and azithromycin treatment in a Bartonella species infected dog. 2016 J Vet Emerg Crit Care (San Antonio) pmid:27074964
Martín JM et al. Azithromycin for the Treatment of Ciclosporin-Induced Gingival Hyperplasia. 2016 Actas Dermosifiliogr pmid:26996332
Petrelli F et al. Poly(ADP-ribose) polymerase is not involved in the neuroprotection exerted by azithromycin against ischemic stroke in mice. 2016 Eur. J. Pharmacol. pmid:27663279
Cheng GS et al. Lung Function Trajectory in Bronchiolitis Obliterans Syndrome after Allogeneic Hematopoietic Cell Transplant. 2016 Ann Am Thorac Soc pmid:27513368
Kobuchi S et al. Transport of Azithromycin into Extravascular Space in Rats. 2016 Antimicrob. Agents Chemother. pmid:27600045
Marks M et al. Prevalence of Active and Latent Yaws in the Solomon Islands 18 Months after Azithromycin Mass Drug Administration for Trachoma. 2016 PLoS Negl Trop Dis pmid:27551787
Samson C et al. Long-term effects of azithromycin in patients with cystic fibrosis. 2016 Respir Med pmid:27492507
Akram FE et al. A combination of silver nanoparticles and visible blue light enhances the antibacterial efficacy of ineffective antibiotics against methicillin-resistant Staphylococcus aureus (MRSA). 2016 Ann. Clin. Microbiol. Antimicrob. pmid:27530257
O'Farrell N Control of gonorrhoea and chlamydia in the UK. 2016 Lancet pmid:27477165
Zhu XH et al. Viral and Bacterial Etiology of Acute Diarrhea among Children under 5 Years of Age in Wuhan, China. 2016 Chin. Med. J. pmid:27503019
Zhao M et al. Comparison of minocycline and azithromycin for the treatment of mild scrub typhus in northern China. 2016 Int. J. Antimicrob. Agents pmid:27449540
Dukers-Muijrers NH et al. Design of the FemCure study: prospective multicentre study on the transmission of genital and extra-genital Chlamydia trachomatis infections in women receiving routine care. 2016 BMC Infect. Dis. pmid:27502928
Huang SW et al. Azithromycin impairs TLR7 signaling in dendritic cells and improves the severity of imiquimod-induced psoriasis-like skin inflammation in mice. 2016 J. Dermatol. Sci. pmid:27449383
Yoshioka D et al. Efficacy of β-Lactam-plus-Macrolide Combination Therapy in a Mouse Model of Lethal Pneumococcal Pneumonia. 2016 Antimicrob. Agents Chemother. pmid:27480866
Jacobsson S et al. WGS analysis and molecular resistance mechanisms of azithromycin-resistant (MIC >2 mg/L) Neisseria gonorrhoeae isolates in Europe from 2009 to 2014. 2016 J. Antimicrob. Chemother. pmid:27432597
Itaqui SR et al. In Vitro Synergism between Azithromycin or Terbinafine and Topical Antimicrobial Agents against Pythium insidiosum. 2016 Antimicrob. Agents Chemother. pmid:27216049
Wang Z and Meenach SA Synthesis and Characterization of Nanocomposite Microparticles (nCmP) for the Treatment of Cystic Fibrosis-Related Infections. 2016 Pharm. Res. pmid:27091030
Phong NC et al. In Vivo Efficacy and Tolerability of Artesunate-Azithromycin for the Treatment of Falciparum Malaria in Vietnam. 2016 Am. J. Trop. Med. Hyg. pmid:27215294
Ab Rahman N et al. Antibiotic prescribing in public and private practice: a cross-sectional study in primary care clinics in Malaysia. 2016 BMC Infect. Dis. pmid:27188538
Brown J et al. Shigellosis: high rates of antibiotic resistance necessitate new treatment recommendations. 2016 Med. J. Aust. pmid:27078594
Ramaiah B et al. High azithromycin concentration in lungs by way of bovine serum albumin microspheres as targeted drug delivery: lung targeting efficiency in albino mice. 2016 Daru pmid:27150818
Rajabi O et al. Topical liposomal azithromycin in the treatment of acute cutaneous leishmaniasis. 2016 Dermatol Ther pmid:27073044
Geisler WM et al. Azithromycin versus Doxycycline for Chlamydia. 2016 N. Engl. J. Med. pmid:27144856
Dunn AL et al. Naegleria fowleri That Induces Primary Amoebic Meningoencephalitis: Rapid Diagnosis and Rare Case of Survival in a 12-Year-Old Caucasian Girl. 2016 Lab Med pmid:26984830
Yelenich-Huss MJ et al. Ozena in Immigrants of Differing Backgrounds. 2016 Am. J. Trop. Med. Hyg. pmid:27114295
Saini H et al. Antimicrobial and antifouling efficacy of urinary catheters impregnated with a combination of macrolide and fluoroquinolone antibiotics against Pseudomonas aeruginosa. 2016 Biofouling pmid:26982572
Vermeersch K et al. The Belgian trial with azithromycin for acute COPD exacerbations requiring hospitalization: an investigator-initiated study protocol for a multicenter, randomized, double-blind, placebo-controlled trial. 2016 Int J Chron Obstruct Pulmon Dis pmid:27099485
Levy V et al. A Case of Persistent and Possibly Treatment Resistant Pharyngeal Gonorrhea. 2016 Sex Transm Dis pmid:26967304
Swatton JE et al. Impact of Azithromycin on the Quorum Sensing-Controlled Proteome of Pseudomonas aeruginosa. 2016 PLoS ONE pmid:26808156
Afshar M et al. Azithromycin use and outcomes in severe sepsis patients with and without pneumonia. 2016 J Crit Care pmid:26803186
Lenehan PJ et al. An evaluation strategy for potential QTc prolongation with chronic azithromycin therapy in cystic fibrosis. 2016 J. Cyst. Fibros. pmid:26698953
Lee H et al. New treatment options for infections caused by increasingly antimicrobial-resistant Neisseria gonorrhoeae. 2016 Expert Rev Anti Infect Ther pmid:26690658
Nakajima T et al. Microbiological and Clinical Effects of Sitafloxacin and Azithromycin in Periodontitis Patients Receiving Supportive Periodontal Therapy. 2016 Antimicrob. Agents Chemother. pmid:26729495
Jentsch HF et al. Nonsurgical therapy of chronic periodontitis with adjunctive systemic azithromycin or amoxicillin/metronidazole. 2016 Clin Oral Investig pmid:26685849
Slade J et al. Chlamydial Pre-Infection Protects from Subsequent Herpes Simplex Virus-2 Challenge in a Murine Vaginal Super-Infection Model. 2016 PLoS ONE pmid:26726882
Lococo F et al. Hemoptysis and Progressive Dyspnea in a 67-Year-Old Woman with History of Renal Transplantation. 2016 Am. J. Respir. Crit. Care Med. pmid:26681504
Mukai S et al. Macrolides sensitize EGFR-TKI-induced non-apoptotic cell death via blocking autophagy flux in pancreatic cancer cell lines. 2016 Int. J. Oncol. pmid:26718641
Miyagawa T et al. Azithromycin recovers reductions in barrier function in human gingival epithelial cells stimulated with tumor necrosis factor-α. 2016 Arch. Oral Biol. pmid:26655749
Smith DJ et al. Pseudomonas aeruginosa antibiotic resistance in Australian cystic fibrosis centres. 2016 Respirology pmid:26711802
Lübbert C Antimicrobial therapy of acute diarrhoea: a clinical review. 2016 Expert Rev Anti Infect Ther pmid:26641310
Al-Hity A and Lockington D Oral azithromycin as the systemic treatment of choice in the treatment of meibomian gland disease. 2016 Clin. Experiment. Ophthalmol. pmid:26441357
Wu TS et al. Postcesarean section wound infection caused by Mycobacterium massiliense. 2016 J Microbiol Immunol Infect pmid:26350122
Unger HW et al. Azithromycin-containing intermittent preventive treatment in pregnancy affects gestational weight gain, an important predictor of birthweight in Papua New Guinea - an exploratory analysis. 2016 Matern Child Nutr pmid:26373537
Zhang Z et al. Clinical effect of azithromycin as an adjunct to non-surgical treatment of chronic periodontitis: a meta-analysis of randomized controlled clinical trials. 2016 J. Periodont. Res. pmid:26362529
Nappe TM et al. Stevens-Johnson syndrome after treatment with azithromycin: an uncommon culprit. 2016 Am J Emerg Med pmid:26194400
Derad I et al. Hypertension and mild chronic kidney disease persist following severe haemolytic uraemic syndrome caused by Shiga toxin-producing Escherichia coli O104:H4 in adults. 2016 Nephrol. Dial. Transplant. pmid:26180049
Steeples LR et al. Real-time PCR using the 529 bp repeat element for the diagnosis of atypical ocular toxoplasmosis. 2016 Br J Ophthalmol pmid:26174811
Arora N et al. Origin of modern syphilis and emergence of a pandemic Treponema pallidum cluster. 2016 Nat Microbiol pmid:27918528
Retallack H et al. Zika virus cell tropism in the developing human brain and inhibition by azithromycin. 2016 Proc. Natl. Acad. Sci. U.S.A. pmid:27911847
Brittain C et al. Gentamicin versus ceftriaxone for the treatment of gonorrhoea (G-TOG trial): study protocol for a randomised trial. 2016 Trials pmid:27881151