| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Airway Obstruction | D000402 | 13 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Diarrhea | D003967 | 32 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Hearing Loss, Sensorineural | D006319 | 8 associated lipids |
| Otitis Media | D010033 | 12 associated lipids |
| Carcinoma, Basal Cell | D002280 | 6 associated lipids |
| Bacterial Infections | D001424 | 21 associated lipids |
| Pain | D010146 | 64 associated lipids |
Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Stout JE and Floto RA | Treatment of Mycobacterium abscessus: all macrolides are equal, but perhaps some are more equal than others. | 2012 | Am. J. Respir. Crit. Care Med. | pmid:23118083 |
| Kanazawa S et al. | Azithromycin and bronchiolitis obliterans. | 2004 | Am. J. Respir. Crit. Care Med. | pmid:14982826 |
| Tsai WC et al. | Azithromycin blocks neutrophil recruitment in Pseudomonas endobronchial infection. | 2004 | Am. J. Respir. Crit. Care Med. | pmid:15361366 |
| Jeong BH et al. | Intermittent antibiotic therapy for nodular bronchiectatic Mycobacterium avium complex lung disease. | 2015 | Am. J. Respir. Crit. Care Med. | pmid:25393520 |
| Restrepo MI and Anzueto A | Reply: Azithromycin: We're there! | 2014 | Am. J. Respir. Crit. Care Med. | pmid:25360733 |
| Hayes D et al. | ABCA3 transporter deficiency. | 2012 | Am. J. Respir. Crit. Care Med. | pmid:23071193 |
| Albert RK et al. | Azithromycin: We're there! | 2014 | Am. J. Respir. Crit. Care Med. | pmid:25360732 |
| Saiman L et al. | Heterogeneity of treatment response to azithromycin in patients with cystic fibrosis. | 2005 | Am. J. Respir. Crit. Care Med. | pmid:16040785 |
| Choi GE et al. | Macrolide treatment for Mycobacterium abscessus and Mycobacterium massiliense infection and inducible resistance. | 2012 | Am. J. Respir. Crit. Care Med. | pmid:22878281 |
| Binder AM et al. | Epidemiology of nontuberculous mycobacterial infections and associated chronic macrolide use among persons with cystic fibrosis. | 2013 | Am. J. Respir. Crit. Care Med. | pmid:23927602 |
| Hodge S et al. | Azithromycin improves macrophage phagocytic function and expression of mannose receptor in chronic obstructive pulmonary disease. | 2008 | Am. J. Respir. Crit. Care Med. | pmid:18420960 |
| O'Beirne SL et al. | Severe Cavitary, Fistulating Mycobacterium avium-intracellulare Complex Disease in an Immunocompetent Host. | 2015 | Am. J. Respir. Crit. Care Med. | pmid:26244303 |
| Angel LF et al. | Azithromycin in bronchiolitis obliterans: is the evidence strong enough? | 2006 | Am. J. Respir. Crit. Care Med. | pmid:16467178 |
| Mertens V et al. | Bile acids aspiration reduces survival in lung transplant recipients with BOS despite azithromycin. | 2011 | Am. J. Transplant. | pmid:21272237 |
| Glanville AR | CLAD: does the Emperor have new clothes? | 2014 | Am. J. Transplant. | pmid:25394597 |
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| Verleden SE et al. | Lymphocytic bronchiolitis after lung transplantation is associated with daily changes in air pollution. | 2012 | Am. J. Transplant. | pmid:22682332 |
| Vanaudenaerde BM et al. | Macrolides inhibit IL17-induced IL8 and 8-isoprostane release from human airway smooth muscle cells. | 2007 | Am. J. Transplant. | pmid:17061983 |
| Greer M et al. | Phenotyping established chronic lung allograft dysfunction predicts extracorporeal photopheresis response in lung transplant patients. | 2013 | Am. J. Transplant. | pmid:23406373 |
| Robertson AG et al. | Targeting allograft injury and inflammation in the management of post-lung transplant bronchiolitis obliterans syndrome. | 2009 | Am. J. Transplant. | pmid:19459806 |
| Ruttens D et al. | Prophylactic Azithromycin Therapy After Lung Transplantation: Post hoc Analysis of a Randomized Controlled Trial. | 2016 | Am. J. Transplant. | pmid:26372728 |
| Amsden GW et al. | Pharmacokinetics of azithromycin and the combination of ivermectin and albendazole when administered alone and concurrently in healthy volunteers. | 2007 | Am. J. Trop. Med. Hyg. | pmid:17556628 |
| O'Brien KS et al. | Mass Azithromycin and Malaria Parasitemia in Niger: Results from a Community-Randomized Trial. | 2017 | Am. J. Trop. Med. Hyg. | pmid:28722569 |
| Stoney RJ et al. | Travelers' Diarrhea and Other Gastrointestinal Symptoms Among Boston-Area International Travelers. | 2017 | Am. J. Trop. Med. Hyg. | pmid:28719282 |
| Miller RS et al. | Effective treatment of uncomplicated Plasmodium falciparum malaria with azithromycin-quinine combinations: a randomized, dose-ranging study. | 2006 | Am. J. Trop. Med. Hyg. | pmid:16525097 |
| Cook JA et al. | Lack of a pharmacokinetic interaction between azithromycin and chloroquine. | 2006 | Am. J. Trop. Med. Hyg. | pmid:16525098 |
| Chetchotisakd P et al. | Maintenance therapy of melioidosis with ciprofloxacin plus azithromycin compared with cotrimoxazole plus doxycycline. | 2001 Jan-Feb | Am. J. Trop. Med. Hyg. | pmid:11425157 |
| Chi KH et al. | Molecular differentiation of Treponema pallidum subspecies in skin ulceration clinically suspected as yaws in Vanuatu using real-time multiplex PCR and serological methods. | 2015 | Am. J. Trop. Med. Hyg. | pmid:25404075 |
| Gingras BA and Jensen JB | Activity of azithromycin (CP-62,993) and erythromycin against chloroquine-sensitive and chloroquine-resistant strains of Plasmodium falciparum in vitro. | 1992 | Am. J. Trop. Med. Hyg. | pmid:1326232 |
| Gao D et al. | Optimal seasonal timing of oral azithromycin for malaria. | 2014 | Am. J. Trop. Med. Hyg. | pmid:25223942 |
| Rosenthal PJ | Azithromycin for Malaria? | 2016 | Am. J. Trop. Med. Hyg. | pmid:27215296 |
| Layegh P et al. | Efficacy of azithromycin versus systemic meglumine antimoniate (Glucantime) in the treatment of cutaneous leishmaniasis. | 2007 | Am. J. Trop. Med. Hyg. | pmid:17620637 |
| Katanami Y et al. | Six Cases of Paratyphoid Fever Due to Salmonella Paratyphi A in Travelers Returning from Myanmar Between July 2014 and August 2015. | 2016 | Am. J. Trop. Med. Hyg. | pmid:27352874 |
| Kumaresan JA and Mecaskey JW | The global elimination of blinding trachoma: progress and promise. | 2003 | Am. J. Trop. Med. Hyg. | pmid:14692677 |
| Phong NC et al. | In Vivo Efficacy and Tolerability of Artesunate-Azithromycin for the Treatment of Falciparum Malaria in Vietnam. | 2016 | Am. J. Trop. Med. Hyg. | pmid:27215294 |
| Yelenich-Huss MJ et al. | Ozena in Immigrants of Differing Backgrounds. | 2016 | Am. J. Trop. Med. Hyg. | pmid:27114295 |
| Krolewiecki A et al. | Activity of azithromycin against Leishmania major in vitro and in vivo. | 2002 | Am. J. Trop. Med. Hyg. | pmid:12408666 |
| Luntamo M et al. | Effect of repeated treatment of pregnant women with sulfadoxine-pyrimethamine and azithromycin on preterm delivery in Malawi: a randomized controlled trial. | 2010 | Am. J. Trop. Med. Hyg. | pmid:21118924 |
| de Oliveira-Silva F et al. | Antileishmanial activity of azithromycin against Leishmania (Leishmania) amazonensis, Leishmania (Viannia) braziliensis, and Leishmania (Leishmania) chagasi. | 2008 | Am. J. Trop. Med. Hyg. | pmid:18458308 |
| Ayele B et al. | Adverse events after mass azithromycin treatments for trachoma in Ethiopia. | 2011 | Am. J. Trop. Med. Hyg. | pmid:21813850 |
| Gebre T et al. | Latrine promotion for trachoma: assessment of mortality from a cluster-randomized trial in Ethiopia. | 2011 | Am. J. Trop. Med. Hyg. | pmid:21896815 |
| Gingras BA and Jensen JB | Antimalarial activity of azithromycin and erythromycin against Plasmodium berghei. | 1993 | Am. J. Trop. Med. Hyg. | pmid:8394660 |
| Å majs D et al. | Macrolide Resistance in the Syphilis Spirochete, Treponema pallidum ssp. pallidum: Can We Also Expect Macrolide-Resistant Yaws Strains? | 2015 | Am. J. Trop. Med. Hyg. | pmid:26217043 |
| Shih CM and Wang CC | Ability of azithromycin in combination with quinine for the elimination of babesial infection in humans. | 1998 | Am. J. Trop. Med. Hyg. | pmid:9790419 |
| Krolewiecki AJ et al. | A randomized clinical trial comparing oral azithromycin and meglumine antimoniate for the treatment of American cutaneous leishmaniasis caused by Leishmania (Viannia) braziliensis. | 2007 | Am. J. Trop. Med. Hyg. | pmid:17978064 |
| Richards FO et al. | No depletion of Wolbachia from Onchocerca volvulus after a short course of rifampin and/or azithromycin. | 2007 | Am. J. Trop. Med. Hyg. | pmid:17984346 |
| Fossa AA et al. | Azithromycin/chloroquine combination does not increase cardiac instability despite an increase in monophasic action potential duration in the anesthetized guinea pig. | 2007 | Am. J. Trop. Med. Hyg. | pmid:17984356 |
| Keenan JD et al. | Clinical activity and polymerase chain reaction evidence of chlamydial infection after repeated mass antibiotic treatments for trachoma. | 2010 | Am. J. Trop. Med. Hyg. | pmid:20207878 |
| Coles CL et al. | Association of mass treatment with azithromycin in trachoma-endemic communities with short-term reduced risk of diarrhea in young children. | 2011 | Am. J. Trop. Med. Hyg. | pmid:21976574 |
| Dunne MW et al. | A double-blind, randomized study of azithromycin compared to chloroquine for the treatment of Plasmodium vivax malaria in India. | 2005 | Am. J. Trop. Med. Hyg. | pmid:16354821 |