| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Airway Obstruction | D000402 | 13 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Diarrhea | D003967 | 32 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Hearing Loss, Sensorineural | D006319 | 8 associated lipids |
| Otitis Media | D010033 | 12 associated lipids |
| Carcinoma, Basal Cell | D002280 | 6 associated lipids |
| Bacterial Infections | D001424 | 21 associated lipids |
| Pain | D010146 | 64 associated lipids |
Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Grimes M et al. | Two mutations associated with macrolide resistance in Treponema pallidum: increasing prevalence and correlation with molecular strain type in Seattle, Washington. | 2012 | Sex Transm Dis | pmid:23191949 |
| Zheng H et al. | Association of the in vitro susceptibility of clinical isolates of chlamydia trachomatis with serovar and duration of antibiotic exposure. | 2015 | Sex Transm Dis | pmid:25668641 |
| Hublikar S et al. | Disseminated gonococcal infection and eculizumab--a "high risk" connection? | 2014 | Sex Transm Dis | pmid:25581812 |
| Cole MJ et al. | Risk factors for antimicrobial-resistant Neisseria gonorrhoeae in Europe. | 2014 | Sex Transm Dis | pmid:25581808 |
| Schillinger JA et al. | Patient-delivered partner treatment with azithromycin to prevent repeated Chlamydia trachomatis infection among women: a randomized, controlled trial. | 2003 | Sex Transm Dis | pmid:12514443 |
| Kerani RP et al. | Gonorrhea treatment practices in the STD Surveillance Network, 2010-2012. | 2015 | Sex Transm Dis | pmid:25504294 |
| Ito S et al. | Haemophilus influenzae Isolated From Men With Acute Urethritis: Its Pathogenic Roles, Responses to Antimicrobial Chemotherapies, and Antimicrobial Susceptibilities. | 2017 | Sex Transm Dis | pmid:28282645 |
| Muldoon EG et al. | Treponema pallidum azithromycin resistance in Dublin, Ireland. | 2012 | Sex Transm Dis | pmid:23001265 |
| Prevalence of the 23S rRNA A2058G point mutation and molecular subtypes in Treponema pallidum in the United States, 2007 to 2009. | 2012 | Sex Transm Dis | pmid:23001267 | |
| Starnino S et al. | Retrospective analysis of antimicrobial susceptibility trends (2000-2009) in Neisseria gonorrhoeae isolates from countries in Latin America and the Caribbean shows evolving resistance to ciprofloxacin, azithromycin and decreased susceptibility to ceftriaxone. | 2012 | Sex Transm Dis | pmid:23001269 |
| Thakur SD et al. | Resistance to Ceftriaxone and Azithromycin in Neisseria gonorrhoeae Isolates From 7 Countries of South America and the Caribbean: 2010-2011. | 2017 | Sex Transm Dis | pmid:28178114 |
| Asbel LE et al. | School-based screening for Chlamydia trachomatis and Neisseria gonorrhoeae among Philadelphia public high school students. | 2006 | Sex Transm Dis | pmid:16614587 |
| Sosa J et al. | High percentages of resistance to tetracycline and penicillin and reduced susceptibility to azithromycin characterize the majority of strain types of Neisseria gonorrhoeae isolates in Cuba, 1995-1998. | 2003 | Sex Transm Dis | pmid:12916137 |
| Ehret JM et al. | A clinical isolate of Neisseria gonorrhoeae with in vitro resistance to erythromycin and decreased susceptibility to azithromycin. | 1996 Jul-Aug | Sex Transm Dis | pmid:8836018 |
| Sahin-Hodoglugil NN et al. | A comparison of cost-effectiveness of three protocols for diagnosis and treatment of gonococcal and chlamydial infections in women in Africa. | 2003 | Sex Transm Dis | pmid:12916139 |
| Beymer MR et al. | Evaluation of gonorrhea test of cure at 1 week in a Los Angeles community-based clinic serving men who have sex with men. | 2014 | Sex Transm Dis | pmid:25211254 |
| Beyda RM et al. | Azithromycin efficacy in the treatment of Chlamydia trachomatis among detained youth. | 2014 | Sex Transm Dis | pmid:25211253 |
| Tyndall MW et al. | Single dose azithromycin for the treatment of chancroid: a randomized comparison with erythromycin. | 1994 Jul-Aug | Sex Transm Dis | pmid:7974076 |
| Batteiger BE | Azithromycin Efficacy in Asymptomatic Rectal Chlamydial Infection in Men Who Have Sex With Men: A More Definitive Answer Soon? | 2017 | Sex Transm Dis | pmid:28604482 |
| Katz KA et al. | Molecular epidemiology of syphilis--San Francisco, 2004-2007. | 2010 | Sex Transm Dis | pmid:20601928 |
| Lavoué V et al. | Screening for Chlamydia trachomatis using self-collected vaginal swabs at a public pregnancy termination clinic in France: results of a screen-and-treat policy. | 2012 | Sex Transm Dis | pmid:22801345 |
| Holman KM et al. | Rapid plasma reagin titer variation in the 2 weeks after syphilis therapy. | 2012 | Sex Transm Dis | pmid:22801348 |
| Bornstein M et al. | Factors Associated With Primary Care Physician Knowledge of the Recommended Regimen for Treating Gonorrhea. | 2017 | Sex Transm Dis | pmid:27898574 |
| Molini BJ et al. | Macrolide Resistance in Treponema pallidum Correlates With 23S rDNA Mutations in Recently Isolated Clinical Strains. | 2016 | Sex Transm Dis | pmid:27513385 |
| Xiridou M et al. | Cost-Effectiveness of Dual Antimicrobial Therapy for Gonococcal Infections Among Men Who Have Sex With Men in the Netherlands. | 2016 | Sex Transm Dis | pmid:27513379 |
| Campos-Outcalt D et al. | Use of directly observed azithromycin treatment for syphilis in a homeless woman. | 2002 | Sex Transm Dis | pmid:12035029 |
| Tapsall JW et al. | Failure of azithromycin therapy in gonorrhea and discorrelation with laboratory test parameters. | 1998 | Sex Transm Dis | pmid:9858344 |
| Lázaro MJ et al. | A case of late-stage lymphogranuloma venereum in a woman in Europe. | 2013 | Sex Transm Dis | pmid:24275729 |
| Abdolrasouli A and Roushan A | Corynebacterium propinquum associated with acute, nongonococcal urethritis. | 2013 | Sex Transm Dis | pmid:24275738 |
| McLean CA et al. | The emergence of Neisseria gonorrhoeae with decreased susceptibility to Azithromycin in Kansas City, Missouri, 1999 to 2000. | 2004 | Sex Transm Dis | pmid:14743069 |
| Farley TA et al. | The acceptability and behavioral effects of antibiotic prophylaxis for syphilis prevention. | 2003 | Sex Transm Dis | pmid:14603093 |
| Noda AA et al. | First Report of the 23S rRNA Gene A2058G Point Mutation Associated With Macrolide Resistance in Treponema pallidum From Syphilis Patients in Cuba. | 2016 | Sex Transm Dis | pmid:27100771 |
| O'Farrell N et al. | Periodic presumptive treatment for cervical infections in service women in 3 border provinces of Laos. | 2006 | Sex Transm Dis | pmid:16645552 |
| Gratrix J et al. | Retrospective review of pharyngeal gonorrhea treatment failures in Alberta, Canada. | 2013 | Sex Transm Dis | pmid:24113412 |
| Peters RP et al. | Gonococcal Conjunctivitis Despite Successful Treatment of Male Urethritis Syndrome. | 2016 | Sex Transm Dis | pmid:26760182 |
| Gratrix J et al. | A Retrospective Review of Treatment Failures Using Azithromycin and Doxycycline in the Treatment of Rectal Chlamydia Infections in Women and Men Who Have Sex With Men. | 2016 | Sex Transm Dis | pmid:26760180 |
| Blandford JM and Gift TL | The cost-effectiveness of single-dose azithromycin for treatment of incubating syphilis. | 2003 | Sex Transm Dis | pmid:12782951 |
| Dillon JA et al. | Antimicrobial susceptibility of Neisseria gonorrhoeae isolates from three Caribbean countries: Trinidad, Guyana, and St. Vincent. | 2001 | Sex Transm Dis | pmid:11518867 |
| Dillon JA et al. | Reduced susceptibility to azithromycin and high percentages of penicillin and tetracycline resistance in Neisseria gonorrhoeae isolates from Manaus, Brazil, 1998. | 2001 | Sex Transm Dis | pmid:11518869 |
| Meltzer MC et al. | Association of Mobiluncus curtisii with recurrence of bacterial vaginosis. | 2008 | Sex Transm Dis | pmid:18418301 |
| Barberá MJ et al. | Mycoplasma genitalium Macrolide and Fluoroquinolone Resistance: Prevalence and Risk Factors Among a 2013-2014 Cohort of Patients in Barcelona, Spain. | 2017 | Sex Transm Dis | pmid:28703723 |
| Yuan LF et al. | Resistance to azithromycin of Neisseria gonorrhoeae isolates from 2 cities in China. | 2011 | Sex Transm Dis | pmid:21844727 |
| Boix V et al. | Polyostotic osteitis in secondary syphilis in an HIV-infected patient. | 2013 | Sex Transm Dis | pmid:23859912 |
| Khosropour CM et al. | Comparing azithromycin and doxycycline for the treatment of rectal chlamydial infection: a retrospective cohort study. | 2014 | Sex Transm Dis | pmid:24413484 |
| Jordan SJ and Geisler WM | Azithromycin for rectal chlamydia: is it time to leave azithromycin on the shelf?...Not yet. | 2014 | Sex Transm Dis | pmid:24413485 |
| Kiddugavu MG et al. | Effectiveness of syphilis treatment using azithromycin and/or benzathine penicillin in Rakai, Uganda. | 2005 | Sex Transm Dis | pmid:15614114 |
| Lau CY and Qureshi AK | Azithromycin versus doxycycline for genital chlamydial infections: a meta-analysis of randomized clinical trials. | 2002 | Sex Transm Dis | pmid:12218839 |
| Singh AE et al. | Gonorrhea Treatment Failures With Oral and Injectable Expanded Spectrum Cephalosporin Monotherapy vs Dual Therapy at 4 Canadian Sexually Transmitted Infection Clinics, 2010-2013. | 2015 | Sex Transm Dis | pmid:25970311 |
| Herchline TE and Inkrott BP | Resistance trends in Neisseria gonorrhoeae in southwestern Ohio. | 2010 | Sex Transm Dis | pmid:19901861 |
| Gose SO et al. | Failure of azithromycin 2.0 g in the treatment of gonococcal urethritis caused by high-level resistance in California. | 2015 | Sex Transm Dis | pmid:25868141 |