Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Airway Obstruction D000402 13 associated lipids
Stomach Ulcer D013276 75 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Hearing Loss, Sensorineural D006319 8 associated lipids
Otitis Media D010033 12 associated lipids
Carcinoma, Basal Cell D002280 6 associated lipids
Bacterial Infections D001424 21 associated lipids
Pain D010146 64 associated lipids
Per page 10 20 50 100 | Total 276

PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Chinh NT et al. A randomized controlled comparison of azithromycin and ofloxacin for treatment of multidrug-resistant or nalidixic acid-resistant enteric fever. 2000 Antimicrob. Agents Chemother. pmid:10858343
Miltner EC and Bermudez LE Mycobacterium avium grown in Acanthamoeba castellanii is protected from the effects of antimicrobials. 2000 Antimicrob. Agents Chemother. pmid:10858369
SendaÄŸ F et al. Single dose oral azithromycin versus seven day doxycycline in the treatment of non-gonococcal mucopurulent endocervicitis. 2000 Aust N Z J Obstet Gynaecol pmid:10870778
Scharfstein JA et al. The cost-effectiveness of prophylaxis for Mycobacterium avium complex in AIDS. 1999 Int J Technol Assess Health Care pmid:10874380
Gruber F et al. Treatment of early syphilis with azithromycin. 2000 J Chemother pmid:10877520
Barsic B et al. Comparison of azithromycin and doxycycline in the treatment of erythema migrans. 2000 May-Jun Infection pmid:10879639
Koch CC et al. Apoptosis, oxidative metabolism and interleukin-8 production in human neutrophils exposed to azithromycin: effects of Streptococcus pneumoniae. 2000 J. Antimicrob. Chemother. pmid:10882684
Herrera D et al. The periodontal abscess (II). Short-term clinical and microbiological efficacy of 2 systemic antibiotic regimes. 2000 J. Clin. Periodontol. pmid:10883868
McBroom JW Medical management of interstitial pregnancy with a retained IUD. A case report. 2000 J Reprod Med pmid:10900583
Drugs for sexually transmitted infections. 1999 Med Lett Drugs Ther pmid:10906932
Gomperts BN and White LK Gonococcal hand abscess. 2000 Pediatr. Infect. Dis. J. pmid:10917235
Hammerschlag MR Treatment of Chlamydia pneumoniae. 2000 Int. J. Antimicrob. Agents pmid:10926449
Rekart M et al. Mass treatment/prophylaxis during an outbreak of infectious syphilis in Vancouver, British Columbia. 2000 Can. Commun. Dis. Rep. pmid:10932390
Ng DK et al. A randomized controlled trial of azithromycin and amoxycillin/clavulanate in the management of subacute childhood rhinosinusitis. 2000 J Paediatr Child Health pmid:10940175
Vranes J Effect of subminimal inhibitory concentrations of azithromycin on adherence of Pseudomonas aeruginosa to polystyrene. 2000 J Chemother pmid:10949976
Dean D et al. Evidence for long-term cervical persistence of Chlamydia trachomatis by omp1 genotyping. 2000 J. Infect. Dis. pmid:10950788
Mandell GL and Coleman EJ Activities of antimicrobial agents against intracellular pneumococci. 2000 Antimicrob. Agents Chemother. pmid:10952618
Thompson C Azithromycin v oxytetracycline for the treatment of non-specific urethritis. 2000 Sex Transm Infect pmid:10961211
Scaglione F et al. In vitro comparative dynamics of modified-release clarithromycin and of azithromycin. 2000 Sep-Oct Chemotherapy pmid:10965100
Guzey M et al. Three-day course of oral azithromycin vs topical oxytetracycline/polymyxin in treatment of active endemic trachoma. 2000 Jul-Aug Jpn. J. Ophthalmol. pmid:10974295