| MeSH term | MeSH ID | Detail |
|---|---|---|
| Empyema, Tuberculous | D004654 | 1 associated lipids |
| Tuberculosis, Ocular | D014392 | 1 associated lipids |
| Encephalomyelitis, Acute Disseminated | D004673 | 1 associated lipids |
| Serositis | D012700 | 1 associated lipids |
| Euthyroid Sick Syndromes | D005067 | 1 associated lipids |
| Immune Reconstitution Inflammatory Syndrome | D054019 | 1 associated lipids |
| Glossitis, Benign Migratory | D005929 | 1 associated lipids |
| Parotid Diseases | D010305 | 1 associated lipids |
| Extensively Drug-Resistant Tuberculosis | D054908 | 1 associated lipids |
| Sacroiliitis | D058566 | 1 associated lipids |
clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with clarithromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Smaill F | Antibiotic susceptibility and resistance testing: an overview. | 2000 | Can. J. Gastroenterol. | pmid:11111110 |
| Fallone CA | Epidemiology of the antibiotic resistance of Helicobacter pylori in Canada. | 2000 | Can. J. Gastroenterol. | pmid:11111111 |
| Chiba N | Effects of in vitro antibiotic resistance on treatment: bismuth-containing regimens. | 2000 | Can. J. Gastroenterol. | pmid:11111112 |
| Garey KW et al. | Long-term clarithromycin decreases prednisone requirements in elderly patients with prednisone-dependent asthma. | 2000 | Chest | pmid:11115481 |
| Jayasagar G et al. | Effect of clarithromycin on the pharmacokinetics of tolbutamide. | 2000 | Drug Metabol Drug Interact | pmid:11116754 |
| Aydin A and Isler M | Efficacy of omeprazole plus two antimicrobials for the eradication of Helicobacter pylori in a Turkish population. | 2000 | Clin Ther | pmid:11117661 |
| Fujiwara T et al. | Helicobacter pylori infection in renal transplant recipients. | 2000 | Transplant. Proc. | pmid:11120026 |
| Okhravi N et al. | Assessment of the effect of oral clarithromycin on visual outcome following presumed bacterial endophthalmitis. | 2000 | Curr. Eye Res. | pmid:11120557 |
| Ichiyama T et al. | Clarithromycin inhibits NF-kappaB activation in human peripheral blood mononuclear cells and pulmonary epithelial cells. | 2001 | Antimicrob. Agents Chemother. | pmid:11120942 |
| Veldhuyzen Van Zanten S et al. | One-week triple therapy with esomeprazole provides effective eradication of Helicobacter pylori in duodenal ulcer disease. | 2000 | Aliment. Pharmacol. Ther. | pmid:11121908 |
| Isomoto H et al. | 5-day vs. 7-day triple therapy with rabeprazole, clarithromycin and amoxicillin for Helicobacter pylori eradication. | 2000 | Aliment. Pharmacol. Ther. | pmid:11121910 |
| Canducci F et al. | A lyophilized and inactivated culture of Lactobacillus acidophilus increases Helicobacter pylori eradication rates. | 2000 | Aliment. Pharmacol. Ther. | pmid:11121911 |
| Toracchio S et al. | Role of antimicrobial susceptibility testing on efficacy of triple therapy in Helicobacter pylori eradication. | 2000 | Aliment. Pharmacol. Ther. | pmid:11121913 |
| Bañuls J et al. | Mycobacterium chelonae infection resistant to clarithromycin in a patient with dermatomyositis. | 2000 | Br. J. Dermatol. | pmid:11122063 |
| Giannopoulos A et al. | Pharmacokinetics of clarithromycin in the prostate: implications for the treatment of chronic abacterial prostatitis. | 2001 | J. Urol. | pmid:11125373 |
| Ozkan Y et al. | Clarithromycin targeting to lung: optimization of the size, morphology and release characteristics of albumin microspheres. | 2000 Sep-Oct | Acta Pol Pharm | pmid:11126029 |
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| Xiao SD et al. | A multicentre study on eradication of Helicobacter pylori using four 1-week triple therapies in China. | 2001 | Aliment. Pharmacol. Ther. | pmid:11136281 |
| Fuchs PC et al. | Influence of variations in test methods on susceptibility of Haemophilus influenzae to ampicillin, azithromycin, clarithromycin, and telithromycin. | 2001 | J. Clin. Microbiol. | pmid:11136745 |
| Rüssmann H et al. | Comparison of fluorescent in situ hybridization and conventional culturing for detection of Helicobacter pylori in gastric biopsy specimens. | 2001 | J. Clin. Microbiol. | pmid:11136788 |
| Kalach N et al. | High levels of resistance to metronidazole and clarithromycin in Helicobacter pylori strains in children. | 2001 | J. Clin. Microbiol. | pmid:11136811 |
| Osato MS et al. | Comparison of the Etest and the NCCLS-approved agar dilution method to detect metronidazole and clarithromycin resistant Helicobacter pylori. | 2001 | Int. J. Antimicrob. Agents | pmid:11137647 |
| Sicilia B et al. | [High eradication rates in Helicobacter pylori infection in patients with duodenal ulcer who failed previous eradication therapy]. | 2000 | Med Clin (Barc) | pmid:11141412 |
| Pilotto A et al. | Incidence of secondary Helicobacter pylori resistance to antibiotics in treatment failures after 1-week proton pump inhibitor-based triple therapies: a prospective study. | 2000 | Dig Liver Dis | pmid:11142574 |
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| Fichtenbaum CJ et al. | Rifabutin but not clarithromycin prevents cryptosporidiosis in persons with advanced HIV infection. | 2000 | AIDS | pmid:11153670 |
| Esposito S et al. | Bactericidal activity of moxifloxacin compared to grepafloxacin and clarithromycin against Streptococcus pneumoniae and Streptococcus pyogenes investigated using an in vitro pharmacodynamic model. | 2000 | J Chemother | pmid:11154028 |
| Fuentes F et al. | In vitro activity of clarithromycin against penicillin-susceptible and penicillin-resistant strains of Streptococcus pneumoniae in a pharmacodynamic simulation model. | 2000 | J Chemother | pmid:11154032 |
| Fanti L et al. | Long-term follow-up and serologic assessment after triple therapy with omeprazole or lansoprazole of Helicobacter-associated duodenal ulcer. | 2001 | J. Clin. Gastroenterol. | pmid:11154169 |
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| Matsumura M et al. | Rapid detection of mutations in the 23S rRNA gene of Helicobacter pylori that confers resistance to clarithromycin treatment to the bacterium. | 2001 | J. Clin. Microbiol. | pmid:11158129 |
| Maggi-Solcà N et al. | Prevalence of Helicobacter pylori resistant strains in the southern part of Switzerland. | 2000 | Clin. Microbiol. Infect. | pmid:11168035 |
| Adamsson I et al. | The use of AP-PCR and flaA-RFLP typing to investigate treatment failure in Helicobacter pylori infection. | 2000 | Clin. Microbiol. Infect. | pmid:11168124 |
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| Esposito S et al. | Activity of moxifloxacin and twelve other antimicrobial agents against 216 clinical isolates of Streptococcus pneumoniae. | 2001 Mar-Apr | Chemotherapy | pmid:11173809 |
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| Conrad DA | Treatment of cat-scratch disease. | 2001 | Curr. Opin. Pediatr. | pmid:11176245 |
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| Moayyedi P et al. | Changing patterns of Helicobacter pylori gastritis in long-standing acid suppression. | 2000 | Helicobacter | pmid:11179985 |
| Mégraud F et al. | Ranitidine bismuth citrate can help to overcome Helicobacter pylori resistance to clarithromycin in vivo. | 2000 | Helicobacter | pmid:11179987 |
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| Hiyama T et al. | Microsatellite instability at D18S61 is associated with no regression of gastric mucosa-associated lymphoid tissue lymphoma after Helicobacter pylori eradication. | 2001 Mar-Apr | Oncol. Rep. | pmid:11182043 |
| de Luis DA et al. | Effect of the treatment of Helicobacter pylori infection on gastric emptying and its influence on the glycaemic control in type 1 diabetes mellitus. | 2001 | Diabetes Res. Clin. Pract. | pmid:11182211 |
| Nightingale CH | A survey of the quality of generic clarithromycin products manufactured in Slovenia and Israel. | 2000 May-Jun | Adv Ther | pmid:11183454 |
| Sato K et al. | Antimicrobial activities of levofloxacin, clarithromycin, and KRM-1648 against Mycobacterium tuberculosis and Mycobacterium avium complex replicating within Mono Mac 6 human macrophage and A-549 type II alveolar cell lines. | 2000 | Int. J. Antimicrob. Agents | pmid:11185410 |
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| Adler JL et al. | Phase III, randomized, double-blind study of clarithromycin extended-release and immediate-release formulations in the treatment of patients with acute exacerbation of chronic bronchitis. | 2000 | Clin Ther | pmid:11192133 |
| Murray JJ et al. | Phase III, randomized, double-blind study of clarithromycin extended-release and immediate-release formulations in the treatment of adult patients with acute maxillary sinusitis. | 2000 | Clin Ther | pmid:11192134 |
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| Badyal DK and Garg SK | Effect of clarithromycin on the pharmacokinetics of carbamazepine in rhesus monkeys. | 2000 | Methods Find Exp Clin Pharmacol | pmid:11196346 |
| Kaipiainen-Seppänen O and Hyvärinen L | Adverse reactions to rifabutin. | 2001 | J. Rheumatol. | pmid:11196537 |
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| Lee AJ and Maddix DS | Rhabdomyolysis secondary to a drug interaction between simvastatin and clarithromycin. | 2001 | Ann Pharmacother | pmid:11197581 |
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| Felley CP et al. | Favourable effect of an acidified milk (LC-1) on Helicobacter pylori gastritis in man. | 2001 | Eur J Gastroenterol Hepatol | pmid:11204805 |
| Bortolotti M et al. | Effect of clarithromycin on esophageal motility. | 2000 | Dis. Esophagus | pmid:11206638 |
| Wong BC et al. | One-week ranitidine bismuth citrate-based triple therapy for the eradication of Helicobacter pylori in Hong Kong with high prevalence of metronidazole resistance. | 2001 | Aliment. Pharmacol. Ther. | pmid:11207516 |
| Fakheri H et al. | Clarithromycin vs. furazolidone in quadruple therapy regimens for the treatment of Helicobacter pylori in a population with a high metronidazole resistance rate. | 2001 | Aliment. Pharmacol. Ther. | pmid:11207517 |
| Nagahara A et al. | Five-day proton pump inhibitor-based quadruple therapy regimen is more effective than 7-day triple therapy regimen for Helicobacter pylori infection. | 2001 | Aliment. Pharmacol. Ther. | pmid:11207518 |
| Iakovlev VP et al. | [Macrolide antibiotic clarithromycin (Klabax) in treatment of community-acquired respiratory tract infections]. | 2000 | Antibiot. Khimioter. | pmid:11210297 |
| Sazykin IuO et al. | [Clarithromycin and tumor chemotherapy]. | 2000 | Antibiot. Khimioter. | pmid:11210301 |
| Pilotto A et al. | Prevalence of Helicobacter pylori resistance to antibiotics in Northeast Italy: a multicentre study. GISU. Interdisciplinary Group for the Study of Ulcer. | 2000 | Dig Liver Dis | pmid:11215555 |
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| Pijlman AH et al. | [Acute delirium, probably precipitated by clarithromycin]. | 2001 | Ned Tijdschr Geneeskd | pmid:11219151 |
| Anzueto A et al. | Comparison of the efficacy of extended-release clarithromycin tablets and amoxicillin/clavulanate tablets in the treatment of acute exacerbation of chronic bronchitis. | 2001 | Clin Ther | pmid:11219481 |
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| Malik R et al. | Treatment of canine leproid granuloma syndrome: preliminary findings in seven dogs. | 2001 | Aust. Vet. J. | pmid:11221566 |
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| Wilcox MH | Clarithromycin and risk of Clostridium difficile-associated diarrhoea. | 2001 | J. Antimicrob. Chemother. | pmid:11222572 |
| Miki H et al. | Early stage gastric MALT lymphoma with high-grade component cured by Helicobacter pylori eradication. | 2001 | J. Gastroenterol. | pmid:11227668 |
| Kim HS et al. | Comparison of the efficacy and safety of different formulations of omeprazole-based triple therapies in the treatment of Helicobacter pylori-positive peptic ulcer. | 2001 | J. Gastroenterol. | pmid:11227677 |
| Kato K et al. | A case of gastric plasmacytoma associated with Helicobacter pylori infection: improvement of abnormal endoscopic and EUS findings after H. pylori eradication. | 2001 | Gastrointest. Endosc. | pmid:11231401 |
| Maconi G et al. | Do some patients with Helicobacter pylori infection benefit from an extension to 2 weeks of a proton pump inhibitor-based triple eradication therapy? | 2001 | Am. J. Gastroenterol. | pmid:11232676 |
| Ozluer SM and De'Ambrosis BJ | Mycobacterium abscessus wound infection. | 2001 | Australas. J. Dermatol. | pmid:11233716 |
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| Cangelosi GA et al. | Phenotypic consequences of red-white colony type variation in Mycobacterium avium. | 2001 | Microbiology (Reading, Engl.) | pmid:11238960 |
| Furuta T et al. | Effect of genotypic differences in CYP2C19 on cure rates for Helicobacter pylori infection by triple therapy with a proton pump inhibitor, amoxicillin, and clarithromycin. | 2001 | Clin. Pharmacol. Ther. | pmid:11240980 |
| Yazawa N et al. | The successful treatment of prurigo pigmentosa with macrolide antibiotics. | 2001 | Dermatology (Basel) | pmid:11244235 |
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| Amábile-Cuevas CF et al. | Comparative in vitro activity of moxifloxacin by E-test against Streptococcus pyogenes. | 2001 | Clin. Infect. Dis. | pmid:11249826 |
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| Vergassola R et al. | [Chlamydia pneumoniae and myocardial infarction (CLINF). Preliminary randomized controlled study with clarithromycin. CLAINF protocol]. | 2000 | Minerva Cardioangiol | pmid:11253326 |
| Bindayna KM | Antibiotic susceptibilities of Helicobacter pylori. | 2001 | Saudi Med J | pmid:11255612 |