| MeSH term | MeSH ID | Detail |
|---|---|---|
| Chlamydial Pneumonia | D061387 | 2 associated lipids |
| Sacroiliitis | D058566 | 1 associated lipids |
| Plaque, Atherosclerotic | D058226 | 7 associated lipids |
| Acute Kidney Injury | D058186 | 34 associated lipids |
| Upper Extremity Deep Vein Thrombosis | D056824 | 1 associated lipids |
| Leprosy, Paucibacillary | D056005 | 2 associated lipids |
| Extensively Drug-Resistant Tuberculosis | D054908 | 1 associated lipids |
| Buruli Ulcer | D054312 | 1 associated lipids |
| Immune Reconstitution Inflammatory Syndrome | D054019 | 1 associated lipids |
| Renal Insufficiency | D051437 | 8 associated lipids |
clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with clarithromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Auw-Hädrich C et al. | [Clarithromycin for monotherapy of B-cell MALT lymphoma?]. | 2013 | Ophthalmologe | pmid:24231914 |
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| Srivastava S et al. | Therapeutic drug management: is it the future of multidrug-resistant tuberculosis treatment? | 2013 | Eur. Respir. J. | pmid:24293417 |
| Formanoy E et al. | Tenosynovitis of the right hand. Mycobacterium kansasii. | 2013 | Neth J Med | pmid:24394739 |
| Pedersen JM et al. | Early identification of clinically relevant drug interactions with the human bile salt export pump (BSEP/ABCB11). | 2013 | Toxicol. Sci. | pmid:24014644 |
| Yoon H et al. | Meta-analysis: is sequential therapy superior to standard triple therapy for Helicobacter pylori infection in Asian adults? | 2013 | J. Gastroenterol. Hepatol. | pmid:24118110 |
| Chen K et al. | Low dose macrolide administration for long term is effective for otitis media with effusion in children. | 2013 | Auris Nasus Larynx | pmid:22673738 |
| Drago F et al. | Acute autoimmune thrombocytopenia and worsening of dermatomyositis after administration of clarithromycin. | 2013 | J. Am. Acad. Dermatol. | pmid:24124859 |
| Herath SC and Poole P | Prophylactic antibiotic therapy for chronic obstructive pulmonary disease (COPD). | 2013 | Cochrane Database Syst Rev | pmid:24288145 |
| Zhu D et al. | Synthesis of 4″-O-desosaminyl clarithromycin derivatives and their anti-bacterial activities. | 2013 | Bioorg. Med. Chem. Lett. | pmid:24139585 |
| Nasa M et al. | Sequential therapy versus standard triple-drug therapy for Helicobacter pylori eradication: a randomized study. | 2013 | Indian J Gastroenterol | pmid:24158898 |
| Kim SY et al. | Comparative study of Helicobacter pylori eradication rates with 5-day quadruple "concomitant" therapy and 7-day standard triple therapy. | 2013 | J. Clin. Gastroenterol. | pmid:22647826 |
| Fagoonee S et al. | Efficacy of cefixime-based triple therapy for Helicobacter pylori eradication: a retrospective study. | 2013 | Panminerva Med | pmid:24088806 |
| Gisbert JP et al. | Second-line therapy with levofloxacin after failure of treatment to eradicate helicobacter pylori infection: time trends in a Spanish Multicenter Study of 1000 patients. | 2013 | J. Clin. Gastroenterol. | pmid:22647827 |
| Piso RJ et al. | Coverage of atypical pathogens for hospitalised patients with community-acquired pneumonia is not guided by clinical parameters. | 2013 | Swiss Med Wkly | pmid:24089030 |
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| Yonezawa H et al. | Impact of Helicobacter pylori biofilm formation on clarithromycin susceptibility and generation of resistance mutations. | 2013 | PLoS ONE | pmid:24039906 |
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| Megraud F et al. | Helicobacter pylori resistance to antibiotics in Europe and its relationship to antibiotic consumption. | 2013 | Gut | pmid:22580412 |
| Guo L et al. | Refining the human iPSC-cardiomyocyte arrhythmic risk assessment model. | 2013 | Toxicol. Sci. | pmid:24052561 |
| Morse AL et al. | A randomized controlled trial comparing sequential with triple therapy for Helicobacter pylori in an Aboriginal community in the Canadian North. | 2013 | Can. J. Gastroenterol. | pmid:24340314 |
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| Kato H et al. | Addition of clarithromycin to lenalidomide/low-dose dexamethasone was effective in a case of relapsed myeloma after long-term use of lenalidomide. | 2013 | Ann. Hematol. | pmid:23625297 |
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| Kwak HM et al. | The efficacy of cefazolin plus macrolide (erythromycin or clarithromycin) versus cefazolin alone in neonatal morbidity and placental inflammation for women with preterm premature rupture of membranes. | 2013 | Placenta | pmid:23465535 |
| Ang TL et al. | Is there still a role for empiric first-line triple therapy using proton pump inhibitor, amoxicillin and clarithromycin for Helicobacter pylori infection in Singapore? Results of a time trend analysis. | 2013 | J Dig Dis | pmid:23253473 |
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| Delavenne X et al. | A semi-mechanistic absorption model to evaluate drug-drug interaction with dabigatran: application with clarithromycin. | 2013 | Br J Clin Pharmacol | pmid:23210726 |
| Duman DG et al. | Saccharomyces boulardii ameliorates clarithromycin- and methotrexate-induced intestinal and hepatic injury in rats. | 2013 | Br. J. Nutr. | pmid:23279717 |
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