clarithromycin

clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.

Cross Reference

Introduction

To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with clarithromycin?

clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with clarithromycin

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Tuberculosis D014376 20 associated lipids
Stomach Ulcer D013276 75 associated lipids
Nocardia Infections D009617 6 associated lipids
Diarrhea D003967 32 associated lipids
Hearing Loss, Sensorineural D006319 8 associated lipids
Otitis Media D010033 12 associated lipids
Carcinoma, Basal Cell D002280 6 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Adenocarcinoma D000230 166 associated lipids
Per page 10 20 50 100 | Total 242

PubChem Associated disorders and diseases

What pathways are associated with clarithromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with clarithromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with clarithromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with clarithromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with clarithromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with clarithromycin?

Mouse Model

Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).

Knock-out

Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).

Experimental Pneumococcal Meningitis

Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with clarithromycin

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Per page 10 20 50 100 | Total 7636
Authors Title Published Journal PubMed Link
Clark JA and Margolis DM A cutaneous lesion in a patient with AIDS: an unusual presentation of infection due to Mycobacterium avium complex. 1993 Clin. Infect. Dis. pmid:8513064
Alba D et al. [Clarithromycin in the treatment of cerebral toxoplasmosis associated with HIV infection]. 1993 Rev Clin Esp pmid:8516514
Alder J et al. Clarithromycin therapy of experimental Treponema pallidum infections in hamsters. 1993 Antimicrob. Agents Chemother. pmid:8494384
Vaara M Outer membrane permeability barrier to azithromycin, clarithromycin, and roxithromycin in gram-negative enteric bacteria. 1993 Antimicrob. Agents Chemother. pmid:8383945
Ximenes E et al. [Ciprofloxacin, clarithromycin, rifampin: in vitro bactericidal activity of double and triple drug combinations against strains of atypical mycobacteria]. 1993 Pathol. Biol. pmid:8233629
Peterson WL et al. Clarithromycin as monotherapy for eradication of Helicobacter pylori: a randomized, double-blind trial. 1993 Am. J. Gastroenterol. pmid:8237933
Yasuda H et al. Interaction between biofilms formed by Pseudomonas aeruginosa and clarithromycin. 1993 Antimicrob. Agents Chemother. pmid:8239580
Walker LL et al. Clarithromycin is bactericidal against strains of Mycobacterium leprae resistant and susceptible to dapsone and rifampin. 1993 Int. J. Lepr. Other Mycobact. Dis. pmid:8326182
Alder J et al. Efficacy of clarithromycin for treatment of experimental Lyme disease in vivo. 1993 Antimicrob. Agents Chemother. pmid:8328782
Mor N and Heifets L Inhibition of intracellular growth of Mycobacterium avium by one pulsed exposure of infected macrophages to clarithromycin. 1993 Antimicrob. Agents Chemother. pmid:8328792
Helm CJ et al. Comparison of topical antibiotics for treating Mycobacterium fortuitum keratitis in an animal model. 1993 Am. J. Ophthalmol. pmid:8250072
Green PA et al. Mycobacterium avium complex parotid lymphadenitis: successful therapy with clarithromycin and ethambutol. 1993 Pediatr. Infect. Dis. J. pmid:8346008
Chien SM et al. Treatment of community-acquired pneumonia. A multicenter, double-blind, randomized study comparing clarithromycin with erythromycin. Canada-Sweden Clarithromycin-Pneumonia Study Group. 1993 Chest pmid:8449054
Watanabe Y et al. Chemical modification of erythromycins. IX. Selective methylation at the C-6 hydroxyl group of erythromycin A oxime derivatives and preparation of clarithromycin. 1993 J. Antibiot. pmid:8501007
Braga PC and Piatti G Sub-lethal concentrations of clarithromycin interfere with the expression of Staphylococcus aureus adhesiveness to human cells. 1993 J Chemother pmid:8371124
Macklin JL et al. A single-blind, randomised, comparative study of clarithromycin and amoxycillin suspensions in the treatment of children with lower respiratory tract infections. 1993 J Chemother pmid:8371127
Ragnaud JM et al. [Cerebral toxoplasmosis in AIDS. 73 cases. Clinical Epidemiology Group on AIDS in Aquitania]. 1993 Presse Med pmid:8378280
Klopman G et al. Anti-Mycobacterium avium activity of quinolones: in vitro activities. 1993 Antimicrob. Agents Chemother. pmid:8239587
Heifets L et al. Mycobacterium avium strains resistant to clarithromycin and azithromycin. 1993 Antimicrob. Agents Chemother. pmid:8031351
Holdcroft C Two new macrolide antibiotics: clarithromycin and azithromycin. 1993 Nurse Pract pmid:8380492