clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with clarithromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (5)
- Drug Metab. Dispos. (1)
- FEMS Immunol. Med. Microbiol. (1)
- Others (5)
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Becker ML et al. | Determinants of potential drug-drug interaction associated dispensing in community pharmacies in the Netherlands. | 2007 | Pharm World Sci | pmid:17187223 |
| Shahbazi Niaz M et al. | Investigation into physical-chemical variables affecting the manufacture and dissolution of wet-milled clarithromycin nanoparticles. | 2014 | Pharm Dev Technol | pmid:24093825 |
| Alkhalidi BA et al. | Development of a predictive in vitro dissolution for clarithromycin granular suspension based on in vitro-in vivo correlations. | 2010 | Pharm Dev Technol | pmid:22716469 |
| Kazama I and Maruyama Y | Differential effects of clarithromycin and azithromycin on delayed rectifier K(+)-channel currents in murine thymocytes. | 2013 | Pharm Biol | pmid:23527897 |
| Hassan ST et al. | In vitro synergistic effect of Hibiscus sabdariffa aqueous extract in combination with standard antibiotics against Helicobacter pylori clinical isolates. | 2016 | Pharm Biol | pmid:26731378 |
| Tse KC et al. | Delusion of worm infestation associated with clarithromycin in a patient on peritoneal dialysis. | 2001 Jul-Aug | Perit Dial Int | pmid:11587409 |
| Curry EM et al. | CAPD peritonitis caused by Mycobacterium rhodesiae. | 2008 Jan-Feb | Perit Dial Int | pmid:18178955 |
| Verbanck JJ et al. | Campylobacter jejuni II peritonitis in a CCPD patient: cure by oral clarithromycin. | 1999 Jan-Feb | Perit Dial Int | pmid:10201350 |
| Giacometti A et al. | Combination studies between polycationic peptides and clinically used antibiotics against Gram-positive and Gram-negative bacteria. | 2000 | Peptides | pmid:11035200 |
| Giacometti A et al. | In vitro activity of amphibian peptides alone and in combination with antimicrobial agents against multidrug-resistant pathogens isolated from surgical wound infection. | 2005 | Peptides | pmid:16269345 |
| Giacometti A et al. | In vitro effect of short-term exposure to two synthetic peptides, alone or in combination with clarithromycin or rifabutin, on Cryptosporidium parvum infectivity. | 2002 | Peptides | pmid:12084535 |
| Kato S et al. | Omeprazole-based dual and triple regimens for Helicobacter pylori eradication in children. | 1997 | Pediatrics | pmid:9200377 |
| Madadi P et al. | Fatal hydrocodone overdose in a child: pharmacogenetics and drug interactions. | 2010 | Pediatrics | pmid:20837591 |
| Bitnun A et al. | Children hospitalized with severe acute respiratory syndrome-related illness in Toronto. | 2003 | Pediatrics | pmid:14523209 |
| Broussard CS et al. | Exposure to antibiotics in a United States-Mexico border birth cohort. | 2010 | Pediatrics | pmid:20457685 |
| Ozdemir R et al. | Clarithromycin in preventing bronchopulmonary dysplasia in Ureaplasma urealyticum-positive preterm infants. | 2011 | Pediatrics | pmid:22123897 |
| Moshkowitz M et al. | One-week triple therapy with omeprazole, clarithromycin, and nitroimidazole for Helicobacter pylori infection in children and adolescents. | 1998 | Pediatrics | pmid:9651466 |
| Glatstein M et al. | Lung abscess due to non-tuberculous, non-Mycobacterium fortuitum in a neonate. | 2012 | Pediatr. Pulmonol. | pmid:22451300 |
| Colin AA and Ali-Dinar T | Aerosolized amikacin and oral clarithromycin to eradicate Mycobacterium abscessus in a patient with cystic fibrosis: an 8-year follow-up. | 2010 | Pediatr. Pulmonol. | pmid:20503290 |
| Liu X et al. | High macrolide resistance in Streptococcus pyogenes strains isolated from children with pharyngitis in China. | 2009 | Pediatr. Pulmonol. | pmid:19360846 |
| Iwanaga K and Carter ER | Mycobacterium abscessus complex lung infection in a toddler with a tracheostomy. | 2014 | Pediatr. Pulmonol. | pmid:23460506 |
| Ordoñez CL et al. | Effect of clarithromycin on airway obstruction and inflammatory markers in induced sputum in cystic fibrosis: a pilot study. | 2001 | Pediatr. Pulmonol. | pmid:11416873 |
| Robinson P et al. | Clarithromycin therapy for patients with cystic fibrosis: a randomized controlled trial. | 2012 | Pediatr. Pulmonol. | pmid:22266895 |
| Bitzan M et al. | Rituximab (B-cell depleting antibody) associated lung injury (RALI): a pediatric case and systematic review of the literature. | 2009 | Pediatr. Pulmonol. | pmid:19681063 |
| Kurz H et al. | Role of Chlamydophila pneumoniae in children hospitalized for community-acquired pneumonia in Vienna, Austria. | 2009 | Pediatr. Pulmonol. | pmid:19670403 |
| Colin AA | Eradication of mycobacterium abscessus in a chronically infected patient with cystic fibrosis. | 2000 | Pediatr. Pulmonol. | pmid:10973047 |
| Galarza M et al. | Pediatric granulomatous cerebral amebiasis: a delayed diagnosis. | 2002 | Pediatr. Neurol. | pmid:11897483 |
| Chaturvedi S et al. | Hemolytic uremic syndrome caused by Bordetella pertussis infection. | 2010 | Pediatr. Nephrol. | pmid:20145955 |
| von König CH | Use of antibiotics in the prevention and treatment of pertussis. | 2005 | Pediatr. Infect. Dis. J. | pmid:15876929 |
| Syrogiannopoulos GA et al. | High prevalence of erythromycin resistance of Streptococcus pyogenes in Greek children. | 2001 | Pediatr. Infect. Dis. J. | pmid:11734765 |
| Baughman AL and Bisgard KM | Need for equivalence testing of efficacy of alternative antibiotics for treatment of pertussis. | 2003 | Pediatr. Infect. Dis. J. | pmid:12586986 |
| Petersen JP et al. | Community outbreak of perianal group A streptococcal infection in Denmark. | 2003 | Pediatr. Infect. Dis. J. | pmid:12586971 |
| Block S et al. | Mycoplasma pneumoniae and Chlamydia pneumoniae in pediatric community-acquired pneumonia: comparative efficacy and safety of clarithromycin vs. erythromycin ethylsuccinate. | 1995 | Pediatr. Infect. Dis. J. | pmid:7667050 |
| Lopes AI et al. | Antibiotic-resistant Helicobacter pylori strains in Portuguese children. | 2005 | Pediatr. Infect. Dis. J. | pmid:15876938 |
| Nightingale CH | Pharmacokinetics and pharmacodynamics of newer macrolides. | 1997 | Pediatr. Infect. Dis. J. | pmid:9109156 |
| Block SL | Causative pathogens, antibiotic resistance and therapeutic considerations in acute otitis media. | 1997 | Pediatr. Infect. Dis. J. | pmid:9109158 |
| Tarlow MJ et al. | Future indications for macrolides. | 1997 | Pediatr. Infect. Dis. J. | pmid:9109159 |
| Green PA et al. | Mycobacterium avium complex parotid lymphadenitis: successful therapy with clarithromycin and ethambutol. | 1993 | Pediatr. Infect. Dis. J. | pmid:8346008 |
| Clinical Perspectives on Clarithromycin in Pediatric Infections. Symposium proceedings. February 19-20, 1993. | 1993 | Pediatr. Infect. Dis. J. | pmid:7905199 | |
| Syrogiannopoulos GA et al. | Two dosages of clarithromycin for five days, amoxicillin/clavulanate for five days or penicillin V for ten days in acute group A streptococcal tonsillopharyngitis. | 2004 | Pediatr. Infect. Dis. J. | pmid:15361727 |
| Yang YJ et al. | Prevalence and rapid identification of clarithromycin-resistant Helicobacter pylori isolates in children. | 2001 | Pediatr. Infect. Dis. J. | pmid:11465837 |
| Guay DR and Craft JC | Overview of the pharmacology of clarithromycin suspension in children and a comparison with that in adults. | 1993 | Pediatr. Infect. Dis. J. | pmid:8295810 |
| Hebert AA et al. | Comparative safety and efficacy of clarithromycin and cefadroxil suspensions in the treatment of mild to moderate skin and skin structure infections in children. | 1993 | Pediatr. Infect. Dis. J. | pmid:8295811 |
| Pukander JS et al. | Clarithromycin vs. amoxicillin suspensions in the treatment of pediatric patients with acute otitis media. | 1993 | Pediatr. Infect. Dis. J. | pmid:8295812 |
| McCarty JM et al. | Comparative safety and efficacy of clarithromycin and amoxicillin/clavulanate in the treatment of acute otitis media in children. | 1993 | Pediatr. Infect. Dis. J. | pmid:8295813 |
| Gooch WM et al. | Clarithromycin and cefaclor suspensions in the treatment of acute otitis media in children. | 1993 | Pediatr. Infect. Dis. J. | pmid:8295814 |
| Still JG et al. | Comparison of clarithromycin and penicillin VK suspensions in the treatment of children with streptococcal pharyngitis and review of currently available alternative antibiotic therapies. | 1993 | Pediatr. Infect. Dis. J. | pmid:8295815 |
| Craft JC and Siepman N | Overview of the safety profile of clarithromycin suspension in pediatric patients. | 1993 | Pediatr. Infect. Dis. J. | pmid:8295816 |
| Klein JO | Clarithromycin: where do we go from here? | 1993 | Pediatr. Infect. Dis. J. | pmid:8295817 |
| Hardy DJ | Extent and spectrum of the antimicrobial activity of clarithromycin. | 1993 | Pediatr. Infect. Dis. J. | pmid:8295818 |
| Gan VN et al. | Penetration of clarithromycin into middle ear fluid of children with acute otitis media. | 1997 | Pediatr. Infect. Dis. J. | pmid:9002099 |
| Prechtl J et al. | Monitoring of antibiotic resistance rates of Helicobacter pylori in Austrian children, 2002-2009. | 2012 | Pediatr. Infect. Dis. J. | pmid:22094633 |
| Bradley JS et al. | Comparative study of levofloxacin in the treatment of children with community-acquired pneumonia. | 2007 | Pediatr. Infect. Dis. J. | pmid:17901791 |
| Kuhn SM et al. | Treatment of Mycobacterium marinum facial abscess using clarithromycin. | 1995 | Pediatr. Infect. Dis. J. | pmid:7567299 |
| Lederer J et al. | Clarithromycin treatment of posttraumatic Mycobacterium fortuitum wound infection. | 1993 | Pediatr. Infect. Dis. J. | pmid:8414785 |
| Lebel MH and Mehra S | Efficacy and safety of clarithromycin versus erythromycin for the treatment of pertussis: a prospective, randomized, single blind trial. | 2001 | Pediatr. Infect. Dis. J. | pmid:11740322 |
| Dierig A et al. | Antibiotic treatment of pertussis: are 7 days really sufficient? | 2015 | Pediatr. Infect. Dis. J. | pmid:25247586 |
| Steele RW et al. | Compliance issues related to the selection of antibiotic suspensions for children. | 2001 | Pediatr. Infect. Dis. J. | pmid:11176558 |
| Klein JO | History of macrolide use in pediatrics. | 1997 | Pediatr. Infect. Dis. J. | pmid:9109154 |
| Klein JO | Clarithromycin and azithromycin. | 1998 | Pediatr. Infect. Dis. J. | pmid:9655546 |
| Al Soub H et al. | Myocardial abscess and bacteremia complicating Mycobacterium fortuitum pacemaker infection: case report and review of the literature. | 2009 | Pediatr. Infect. Dis. J. | pmid:19859019 |
| McCracken GH | Microbiologic activity of the newer macrolide antibiotics. | 1997 | Pediatr. Infect. Dis. J. | pmid:9109155 |
| Tarlow MJ | Macrolides in the management of streptococcal pharyngitis/tonsillitis. | 1997 | Pediatr. Infect. Dis. J. | pmid:9109157 |
| Ferguson PJ and Saulsbury FT | Successful treatment of chronic Mycobacterium abscessus otitis media with clarithromycin. | 1996 | Pediatr. Infect. Dis. J. | pmid:8866816 |
| Freyne B and Curtis N | Mycobacterium gordonae Skin Infection in an Immunocompetent Child. | 2017 | Pediatr. Infect. Dis. J. | pmid:28403059 |
| Shimizu T et al. | Case of intrafamilial Helicobacter pylori reinfection after successful eradication therapy. | 2000 | Pediatr. Infect. Dis. J. | pmid:11001123 |
| Reid R et al. | Pneumococcal meningitis during therapy of otitis media with clarithromycin. | 1995 | Pediatr. Infect. Dis. J. | pmid:8786899 |
| McLinn S and Williams D | Incidence of antibiotic-resistant Streptococcus pneumoniae and beta-lactamase-positive Haemophilus influenzae in clinical isolates from patients with otitis media. | 1996 | Pediatr. Infect. Dis. J. | pmid:8878239 |
| Mason EO et al. | Macrolide resistance among middle ear isolates of Streptococcus pneumoniae observed at eight United States pediatric centers: prevalence of M and MLSB phenotypes. | 2003 | Pediatr. Infect. Dis. J. | pmid:12867838 |
| Lindeboom JA et al. | Esthetic outcome of surgical excision versus antibiotic therapy for nontuberculous mycobacterial cervicofacial lymphadenitis in children. | 2009 | Pediatr. Infect. Dis. J. | pmid:19773678 |
| Cohen M et al. | Histologic findings in "ex- Helicobacter pylori" gastric biopsies of pediatric patients. | 2005 Jul-Aug | Pediatr. Dev. Pathol. | pmid:16010501 |
| Woo MS et al. | Pediatric transplant grand rounds. A case presentation: skin lesions in a post-lung transplant patient. | 1997 | Pediatr Transplant | pmid:10084776 |
| Kalman S et al. | Mycoplasma pneumoniae infection in a child after renal transplantation. | 2004 | Pediatr Transplant | pmid:15367286 |
| Wiedermann BL | Macrolides: clarithromycin and azithromycin. | 1998 | Pediatr Rev | pmid:9654947 |
| Hayashi H et al. | Helicobacter pylori infection in children with chronic idiopathic thrombocytopenic purpura. | 2005 | Pediatr Int | pmid:15910453 |
| Ciftçi E et al. | Investigation of risk factors for tonsillopharyngitis with macrolide resistant Streptococcus pyogenes in Turkish children. | 2002 | Pediatr Int | pmid:12421263 |
| Kato S and Fujimura S | Primary antimicrobial resistance of Helicobacter pylori in children during the past 9 years. | 2010 | Pediatr Int | pmid:19563459 |
| Suzuki R et al. | Sinobronchial syndrome treated as intractable asthma. | 2018 | Pediatr Int | pmid:30320426 |
| Okuda M et al. | Nationwide survey of Helicobacter pylori treatment for children and adolescents in Japan. | 2017 | Pediatr Int | pmid:27223686 |
| Nishio N et al. | Cat scratch disease with encephalopathy in a 9-year-old girl. | 2008 | Pediatr Int | pmid:19067901 |
| Defilippi AC et al. | Changes in blood eosinophil numbers during Mycoplasma pneumoniae infection in wheezing and non-wheezing, atopic and non-atopic children. | 2008 | Pediatr Int | pmid:19261132 |
| Sasaoka Y et al. | Neonatal apnea with Chlamydia pneumoniae infection. | 2017 | Pediatr Int | pmid:28102626 |
| Kurekci AE et al. | Complete platelet recovery after treatment of Helicobacter pylori infection in a child with chronic immune thrombocytopenic purpura: a case report. | 2004 Oct-Nov | Pediatr Hematol Oncol | pmid:15626015 |
| Bay A et al. | Helicobacter pylori infection-related pancytopenia in a young boy. | 2011 | Pediatr Hematol Oncol | pmid:21728722 |
| Mytinger JR et al. | Henoch-Schönlein purpura associated with Helicobacter pylori infection in a child. | 2008 Nov-Dec | Pediatr Dermatol | pmid:19067870 |
| Nanda S et al. | Multidrug-resistant cutaneous tuberculosis: response to therapy. | 2003 Nov-Dec | Pediatr Dermatol | pmid:14651584 |
| Martire B et al. | Persistent B-cell lymphopenia, multiorgan disease, and erythema multiforme caused by Mycoplasma pneumoniae infection. | 2005 Nov-Dec | Pediatr Dermatol | pmid:16354262 |
| Bilgili SG et al. | Phototoxic dermatitis due to Chenopodium album in a child. | 2011 Nov-Dec | Pediatr Dermatol | pmid:21854411 |
| Lindeboom JA | Facial Skin Lesions in Children Caused by Nontuberculous Mycobacteria. | Pediatr Dermatol | pmid:26823205 | |
| Brantley JS et al. | Cutaneous Infection with Mycobacterium abscessus in a child. | 2006 Mar-Apr | Pediatr Dermatol | pmid:16650219 |
| Jang HS et al. | Successful treatment of localized cutaneous infection caused by Mycobacterium scrofulaceum with clarithromycin. | 2005 Sep-Oct | Pediatr Dermatol | pmid:16191006 |
| van Doorn HR et al. | Widened coronary arteries in a feverish child. | 2006 Jul-Aug | Pediatr Cardiol | pmid:16830076 |
| Russo G et al. | Effect of eradication of Helicobacter pylori in children with chronic immune thrombocytopenia: a prospective, controlled, multicenter study. | 2011 | Pediatr Blood Cancer | pmid:20830773 |
| Andrianov M et al. | A 15-year-old boy with abdominal pain, growth retardation, and anemia secondary to Helicobacter pylori-associated peptic ulcer. | 2015 | Pediatr Ann | pmid:25806733 |
| Koutsoubari I et al. | Effect of clarithromycin on acute asthma exacerbations in children: an open randomized study. | 2012 | Pediatr Allergy Immunol | pmid:22433020 |
| Akelma AZ et al. | Clarithromycin in treatment of acute asthma exacerbations: principles of appropriate antibiotic use. | 2012 | Pediatr Allergy Immunol | pmid:22984834 |
| Novembre E et al. | Systemic treatment of rhinosinusitis in children. | 2007 | Pediatr Allergy Immunol | pmid:17767611 |
| Zhang XR et al. | Pharmacokinetics of clarithromycin citrate salt after oral administration to beagle dogs and food effects on its absorption. | 2008 Nov-Dec | PDA J Pharm Sci Technol | pmid:19634347 |
| McLean S and Sheikh A | Effectiveness, tolerability and safety of azithromycin 1% in DuraSite for acute bacterial conjunctivitis. | 2010 | Patient Prefer Adherence | pmid:20517467 |
| Grove DI et al. | Comparison of culture, histopathology and urease testing for the diagnosis of Helicobacter pylori gastritis and susceptibility to amoxycillin, clarithromycin, metronidazole and tetracycline. | 1998 | Pathology | pmid:9643503 |