clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with clarithromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (5)
- Drug Metab. Dispos. (1)
- FEMS Immunol. Med. Microbiol. (1)
- Others (5)
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Formanoy E et al. | Tenosynovitis of the right hand. Mycobacterium kansasii. | 2013 | Neth J Med | pmid:24394739 |
| Patel AM et al. | Statin toxicity from macrolide antibiotic coprescription: a population-based cohort study. | 2013 | Ann. Intern. Med. | pmid:23778904 |
| Krashias G et al. | Prevalence of Helicobacter pylori cagA and vacA genes in Cypriot patients. | 2013 | J Infect Dev Ctries | pmid:24042099 |
| Nguyen L and Taylor-Gjevre RM | An emerging role for clarithromycin in adult-onset still disease? | 2013 | J Clin Rheumatol | pmid:24048102 |
| Trespalacios AA et al. | Phenotypic and genotypic analysis of clarithromycin-resistant Helicobacter pylori from Bogotá D.C., Colombia. | 2013 | J. Microbiol. | pmid:23990295 |
| Lee YC et al. | The benefit of mass eradication of Helicobacter pylori infection: a community-based study of gastric cancer prevention. | 2013 | Gut | pmid:22698649 |
| Saviola G et al. | Clarithromycin in rheumatoid arthritis: the addition to methotrexate and low-dose methylprednisolone induces a significant additive value--a 24-month single-blind pilot study. | 2013 | Rheumatol. Int. | pmid:23864141 |
| Amado-RodrÃguez L et al. | Anti-inflammatory effects of clarithromycin in ventilator-induced lung injury. | 2013 | Respir. Res. | pmid:23663489 |
| Pereira JM et al. | Interplay of degradation, dissolution and stabilization of clarithromycin and its amorphous solid dispersions. | 2013 | Mol. Pharm. | pmid:24116899 |
| Huang J et al. | Randomised controlled trial: sequential vs. standard triple therapy for Helicobacter pylori infection in Chinese children-a multicentre, open-labelled study. | 2013 | Aliment. Pharmacol. Ther. | pmid:24117692 |
| Pedersen JM et al. | Early identification of clinically relevant drug interactions with the human bile salt export pump (BSEP/ABCB11). | 2013 | Toxicol. Sci. | pmid:24014644 |
| Yoon H et al. | Meta-analysis: is sequential therapy superior to standard triple therapy for Helicobacter pylori infection in Asian adults? | 2013 | J. Gastroenterol. Hepatol. | pmid:24118110 |
| Chen K et al. | Low dose macrolide administration for long term is effective for otitis media with effusion in children. | 2013 | Auris Nasus Larynx | pmid:22673738 |
| Drago F et al. | Acute autoimmune thrombocytopenia and worsening of dermatomyositis after administration of clarithromycin. | 2013 | J. Am. Acad. Dermatol. | pmid:24124859 |
| Zhu D et al. | Synthesis of 4″-O-desosaminyl clarithromycin derivatives and their anti-bacterial activities. | 2013 | Bioorg. Med. Chem. Lett. | pmid:24139585 |
| Nasa M et al. | Sequential therapy versus standard triple-drug therapy for Helicobacter pylori eradication: a randomized study. | 2013 | Indian J Gastroenterol | pmid:24158898 |
| Kim SY et al. | Comparative study of Helicobacter pylori eradication rates with 5-day quadruple "concomitant" therapy and 7-day standard triple therapy. | 2013 | J. Clin. Gastroenterol. | pmid:22647826 |
| Fagoonee S et al. | Efficacy of cefixime-based triple therapy for Helicobacter pylori eradication: a retrospective study. | 2013 | Panminerva Med | pmid:24088806 |
| Gisbert JP et al. | Second-line therapy with levofloxacin after failure of treatment to eradicate helicobacter pylori infection: time trends in a Spanish Multicenter Study of 1000 patients. | 2013 | J. Clin. Gastroenterol. | pmid:22647827 |
| Piso RJ et al. | Coverage of atypical pathogens for hospitalised patients with community-acquired pneumonia is not guided by clinical parameters. | 2013 | Swiss Med Wkly | pmid:24089030 |
| Guo L et al. | Refining the human iPSC-cardiomyocyte arrhythmic risk assessment model. | 2013 | Toxicol. Sci. | pmid:24052561 |
| Wang S et al. | A supra-monolayer nanopattern for organic nanoparticle array deposition. | 2013 | ACS Appl Mater Interfaces | pmid:23480527 |
| Raghunatha K and George JP | Periodontal tissue and serum concentration of clarithromycin after systemic administration in patients affected by chronic periodontitis. | 2013 | J. Periodontol. | pmid:23451987 |
| Liang X et al. | Efficacy of bismuth-containing quadruple therapies for clarithromycin-, metronidazole-, and fluoroquinolone-resistant Helicobacter pylori infections in a prospective study. | 2013 | Clin. Gastroenterol. Hepatol. | pmid:23376004 |
| Calza P et al. | Fate of selected pharmaceuticals in river waters. | 2013 | Environ Sci Pollut Res Int | pmid:22851223 |
| Morse AL et al. | A randomized controlled trial comparing sequential with triple therapy for Helicobacter pylori in an Aboriginal community in the Canadian North. | 2013 | Can. J. Gastroenterol. | pmid:24340314 |
| Pan W et al. | Effects of clopidogrel and clarithromycin on the disposition of sibutramine and its active metabolites M1 and M2 in relation to CYP2B6*6 polymorphism. | 2013 | Xenobiotica | pmid:22830954 |
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| Evdokimova AG et al. | [New approaches to therapy of Helicobacterpylori infection (by the materials of the Maastricht Consensus-IV, Florence, 2010)]. | 2013 | Antibiot. Khimioter. | pmid:24640139 |
| Shinahara W et al. | Immunomodulator clarithromycin enhances mucosal and systemic immune responses and reduces re-infection rate in pediatric patients with influenza treated with antiviral neuraminidase inhibitors: a retrospective analysis. | 2013 | PLoS ONE | pmid:23875018 |
| Friedman ND et al. | Mycobacterium ulcerans disease: experience with primary oral medical therapy in an Australian cohort. | 2013 | PLoS Negl Trop Dis | pmid:23875050 |
| Suzuki RB et al. | Low Helicobacter pylori primary resistance to clarithromycin in gastric biopsy specimens from dyspeptic patients of a city in the interior of São Paulo, Brazil. | 2013 | BMC Gastroenterol | pmid:24305035 |
| Yano K et al. | Clinical outcome of the chronic flexor tenosynovitis in the hand caused by non-tuberculous mycobacterium treated by extensive tenosynovectomy and drugs. | 2013 | J Plast Surg Hand Surg | pmid:23875916 |
| Trifan A et al. | Pseudomembranous colitis associated with a triple therapy for Helicobacter pylori eradication. | 2013 | World J. Gastroenterol. | pmid:24259981 |
| Laving A et al. | Effectiveness of sequential v. standard triple therapy for treatment of Helicobacter pylori infection in children in Nairobi, Kenya. | 2013 | S. Afr. Med. J. | pmid:24300630 |
| Venerito M et al. | Meta-analysis of bismuth quadruple therapy versus clarithromycin triple therapy for empiric primary treatment of Helicobacter pylori infection. | 2013 | Digestion | pmid:23880479 |
| Cecchini MP et al. | Might Helicobacter pylori infection be associated with distortion on taste perception? | 2013 | Med. Hypotheses | pmid:23845559 |
| Delgado JS et al. | Granulomatous gastritis and Helicobacter pylori infection. | 2013 | Isr. Med. Assoc. J. | pmid:23882902 |
| Lee HJ et al. | Eradication of Helicobacter pylori according to 23S ribosomal RNA point mutations associated with clarithromycin resistance. | 2013 | J. Infect. Dis. | pmid:23801607 |
| Bustamante-Rengifo JA et al. | In vitro effect of amoxicillin and clarithromycin on the 3' region of cagA gene in Helicobacter pylori isolates. | 2013 | World J. Gastroenterol. | pmid:24106405 |
| Shallom SJ et al. | New rapid scheme for distinguishing the subspecies of the Mycobacterium abscessus group and identifying Mycobacterium massiliense isolates with inducible clarithromycin resistance. | 2013 | J. Clin. Microbiol. | pmid:23804391 |
| Greupink R et al. | Semi-mechanistic physiologically-based pharmacokinetic modeling of clinical glibenclamide pharmacokinetics and drug-drug-interactions. | 2013 | Eur J Pharm Sci | pmid:23806476 |
| Park CW et al. | Advanced spray-dried design, physicochemical characterization, and aerosol dispersion performance of vancomycin and clarithromycin multifunctional controlled release particles for targeted respiratory delivery as dry powder inhalation aerosols. | 2013 | Int J Pharm | pmid:23820131 |
| Yu Q et al. | Treatment of pulmonary mucosa-associated lymphoid tissue lymphoma with clarithromycin. | 2013 | Chin. Med. J. | pmid:23786961 |
| Zhuo FL et al. | Clinical isolates of Mycobacterium abscessus in Guangzhou area most possibly from the environmental infection showed variable susceptibility. | 2013 | Chin. Med. J. | pmid:23673103 |
| Seck A et al. | Primary antibiotic resistance and associated mechanisms in Helicobacter pylori isolates from Senegalese patients. | 2013 | Ann. Clin. Microbiol. Antimicrob. | pmid:23298145 |
| Rossi A et al. | BiRd (clarithromycin, lenalidomide, dexamethasone): an update on long-term lenalidomide therapy in previously untreated patients with multiple myeloma. | 2013 | Blood | pmid:23299315 |
| Andersen JT et al. | Clarithromycin in early pregnancy and the risk of miscarriage and malformation: a register based nationwide cohort study. | 2013 | PLoS ONE | pmid:23301061 |
| Kwak HM et al. | The efficacy of cefazolin plus macrolide (erythromycin or clarithromycin) versus cefazolin alone in neonatal morbidity and placental inflammation for women with preterm premature rupture of membranes. | 2013 | Placenta | pmid:23465535 |
| Huang HC et al. | Primary central nervous system diffuse large B cell lymphoma transformed from orbital mucosa-associated lymphoid tissue lymphoma: complete response to combined intrathecal and systemic rituximab. | 2013 | Ann. Hematol. | pmid:23242476 |
| Ang TL et al. | Is there still a role for empiric first-line triple therapy using proton pump inhibitor, amoxicillin and clarithromycin for Helicobacter pylori infection in Singapore? Results of a time trend analysis. | 2013 | J Dig Dis | pmid:23253473 |
| Danilko L et al. | [Clarithromycin therapy of a B cell MALT lymphoma]. | 2013 | Ophthalmologe | pmid:23224128 |
| Liang JH et al. | Synthesis, antibacterial activity and docking of 14-membered 9-O-(3-arylalkyl) oxime 11,12-cyclic carbonate ketolides. | 2013 | Eur J Med Chem | pmid:23202851 |
| Delavenne X et al. | A semi-mechanistic absorption model to evaluate drug-drug interaction with dabigatran: application with clarithromycin. | 2013 | Br J Clin Pharmacol | pmid:23210726 |
| Duman DG et al. | Saccharomyces boulardii ameliorates clarithromycin- and methotrexate-induced intestinal and hepatic injury in rats. | 2013 | Br. J. Nutr. | pmid:23279717 |
| Prasertpetmanee S et al. | Improved efficacy of proton pump inhibitor - amoxicillin - clarithromycin triple therapy for Helicobacter pylori eradication in low clarithromycin resistance areas or for tailored therapy. | 2013 | Helicobacter | pmid:23356886 |
| Nakamura Y et al. | Optimal duration of macrolide treatment for chronic sinusitis after endoscopic sinus surgery. | 2013 | Auris Nasus Larynx | pmid:23107100 |
| Kazama I and Maruyama Y | Differential effects of clarithromycin and azithromycin on delayed rectifier K(+)-channel currents in murine thymocytes. | 2013 | Pharm Biol | pmid:23527897 |
| Kawai Y et al. | Therapeutic efficacy of macrolides, minocycline, and tosufloxacin against macrolide-resistant Mycoplasma pneumoniae pneumonia in pediatric patients. | 2013 | Antimicrob. Agents Chemother. | pmid:23459497 |
| Sardarian H et al. | Comparison of hybrid and sequential therapies for Helicobacter pylori eradication in Iran: a prospective randomized trial. | 2013 | Helicobacter | pmid:23121338 |
| Liou JM et al. | Sequential versus triple therapy for the first-line treatment of Helicobacter pylori: a multicentre, open-label, randomised trial. | 2013 | Lancet | pmid:23158886 |
| Thomas M et al. | Periprosthetic atypical mycobacterial infection in breast implants: a new kid on the block! | 2013 | J Plast Reconstr Aesthet Surg | pmid:23122691 |
| Pandey SK et al. | Antimalarial interaction of quinine and quinidine with clarithromycin. | 2013 | Parasitology | pmid:23137860 |
| Lahbabi M et al. | Sequential therapy versus standard triple-drug therapy for Helicobacter pylori eradication: result of the HPFEZ randomised study. | 2013 | Clin Res Hepatol Gastroenterol | pmid:23168228 |
| Sarkeshikian SS et al. | Azithromycin based triple therapy versus standard clarithromycin based triple therapy in eradication of Helicobacter pylori infection in Iran: a randomized controlled clinical trial. | 2013 | Turk J Gastroenterol | pmid:23794338 |
| Uthman MM et al. | Interventions for the prevention of mycobacterium avium complex in adults and children with HIV. | 2013 | Cochrane Database Syst Rev | pmid:23633339 |
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| Bradbeer L et al. | Childhood headache and H. pylori--a possible association. | 2013 | Aust Fam Physician | pmid:23529524 |
| Yula E et al. | Detection of primary clarithromycin resistance of Helicobacter pylori and association between cagA (+) status and clinical outcome. | 2013 | Folia Microbiol. (Praha) | pmid:22956464 |
| Zhou L et al. | Cutaneous Mycobacterium intracellulare infection in an immuno-competent person. | 2013 | Acta Derm. Venereol. | pmid:23532357 |
| Marin AC et al. | A review of rescue regimens after clarithromycin-containing triple therapy failure (for Helicobacter pylori eradication). | 2013 | Expert Opin Pharmacother | pmid:23537368 |
| Phunpruch S et al. | A role for 16S rRNA dimethyltransferase (ksgA) in intrinsic clarithromycin resistance in Mycobacterium tuberculosis. | 2013 | Int. J. Antimicrob. Agents | pmid:23541074 |
| Alhajlan M et al. | Efficacy and safety of liposomal clarithromycin and its effect on Pseudomonas aeruginosa virulence factors. | 2013 | Antimicrob. Agents Chemother. | pmid:23545534 |
| Goh IX et al. | Cytochrome P450 drug interactions with statin therapy. | 2013 | Singapore Med J | pmid:23546024 |
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| Seneviratne K and Herieka E | A rifampicin-resistant Mycobacterium marinum infection in a newly diagnosed HIV-1 individual. | 2013 | Int J STD AIDS | pmid:23512514 |
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| Karmakar S et al. | Hypokalemia: a potent risk for QTc prolongation in clarithromycin treated rats. | 2013 | Eur. J. Pharmacol. | pmid:23567068 |
| Benajah DA et al. | Prevalence of Helicobacter pylori and its recurrence after successful eradication in a developing nation (Morocco). | 2013 | Clin Res Hepatol Gastroenterol | pmid:23567104 |
| Quinney SK et al. | Rate of onset of inhibition of gut-wall and hepatic CYP3A by clarithromycin. | 2013 | Eur. J. Clin. Pharmacol. | pmid:22777148 |
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| Georgopoulos SD et al. | Clinical evaluation of a ten-day regimen with esomeprazole, metronidazole, amoxicillin, and clarithromycin for the eradication of Helicobacter pylori in a high clarithromycin resistance area. | 2013 | Helicobacter | pmid:23714140 |
| Koh WJ et al. | Successful treatment of Mycobacterium massiliense lung disease with oral antibiotics only. | 2013 | Antimicrob. Agents Chemother. | pmid:23183432 |
| Cerqueira RM et al. | Cumulative Helicobacter pylori eradication therapy in obese patients undergoing gastric bypass surgery. | 2013 | Obes Surg | pmid:23054570 |
| Zendedel A et al. | Antibiotic resistance of Helicobacter pylori in Mashhad, Iran. | 2013 | J Pak Med Assoc | pmid:23914633 |
| Maggi P et al. | Fatal fulminant hepatitis following administration of clarithromycin in a patient chronically treated with antipsycotic drugs. | 2013 | Immunopharmacol Immunotoxicol | pmid:22804484 |
| Haider M et al. | Post-operative sinus formation due to Mycobacterium abscessus: a case report. | 2013 | Indian J Tuberc | pmid:24000496 |
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| Miyauchi R et al. | Clarithromycin-induced haemorrhagic colitis. | 2013 | BMJ Case Rep | pmid:23964038 |
| Ergül B et al. | The efficacy of two-week quadruple first-line therapy with bismuth, lansoprazole, amoxicillin, clarithromycin on Helicobacter pylori eradication: a prospective study. | 2013 | Helicobacter | pmid:24011287 |
| Gandhi S et al. | Calcium-channel blocker-clarithromycin drug interactions and acute kidney injury. | 2013 | JAMA | pmid:24346990 |
| Yu RX et al. | Köebner phenomenon induced by cupping therapy in a psoriasis patient. | 2013 | Dermatol. Online J. | pmid:24011324 |
| Abenavoli L et al. | Association between non-alcoholic fatty liver disease, insulin resistance and Helicobacter pylori. | 2013 | Med. Hypotheses | pmid:24011768 |
| Nagaoka K et al. | Macrolides inhibit Fusobacterium nucleatum-induced MUC5AC production in human airway epithelial cells. | 2013 | Antimicrob. Agents Chemother. | pmid:23380724 |
| Moriya S et al. | Macrolide antibiotics block autophagy flux and sensitize to bortezomib via endoplasmic reticulum stress-mediated CHOP induction in myeloma cells. | 2013 | Int. J. Oncol. | pmid:23546223 |
| Akiyoshi T et al. | Mechanism-based inhibition profiles of erythromycin and clarithromycin with cytochrome P450 3A4 genetic variants. | 2013 | Drug Metab. Pharmacokinet. | pmid:23514827 |