clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with clarithromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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VanderHeyden TR et al. | Granulomatous hepatitis due to Bartonella henselae infection in an immunocompetent patient. | 2012 | BMC Infect. Dis. | pmid:22269175 |
Glatstein M et al. | Lung abscess due to non-tuberculous, non-Mycobacterium fortuitum in a neonate. | 2012 | Pediatr. Pulmonol. | pmid:22451300 |
Matsushima M and Takagi A | "Is it effective?" to "How to use it?": the era has changed in probiotics and functional food products against Helicobacter pylori infection. | 2012 | J. Gastroenterol. Hepatol. | pmid:22515805 |
Fujita Y et al. | Pulmonary Actinomyces graevenitzii infection presenting as organizing pneumonia diagnosed by PCR analysis. | 2012 | J. Med. Microbiol. | pmid:22516132 |
Albaugh DR et al. | Time-dependent inhibition and estimation of CYP3A clinical pharmacokinetic drug-drug interactions using plated human cell systems. | 2012 | Drug Metab. Dispos. | pmid:22490230 |
Stout JE and Floto RA | Treatment of Mycobacterium abscessus: all macrolides are equal, but perhaps some are more equal than others. | 2012 | Am. J. Respir. Crit. Care Med. | pmid:23118083 |
Park HS et al. | Placental transfer of clarithromycin in human pregnancies with preterm premature rupture of membranes. | 2012 | J Perinat Med | pmid:23095192 |
Perić A et al. | Effect of long-term, low-dose clarithromycin on T helper 2 cytokines, eosinophilic cationic protein and the 'regulated on activation, normal T cell expressed and secreted' chemokine in the nasal secretions of patients with nasal polyposis. | 2012 | J Laryngol Otol | pmid:22559798 |
Yamazaki Y et al. | Antimicrobial and anti-inflammatory effects of clarithromycin on Mycobacterium avium complex replication in cultured human bronchial epithelial cells. | 2012 | J. Infect. Chemother. | pmid:22370922 |
Kim HS et al. | Serial CT findings of Mycobacterium massiliense pulmonary disease compared with Mycobacterium abscessus disease after treatment with antibiotic therapy. | 2012 | Radiology | pmid:22371609 |
Hutson JR et al. | Use of clarithromycin and adverse cardiovascular events among older patients receiving donepezil: a population-based, nested case-control study. | 2012 | Drugs Aging | pmid:22372724 |
Hegazy SK et al. | Effect of clarithromycin and fluconazole on the pharmacokinetics of montelukast in human volunteers. | 2012 | Eur. J. Clin. Pharmacol. | pmid:22392555 |
Valizadeh H et al. | Antibacterial activity of clarithromycin loaded PLGA nanoparticles. | 2012 | Pharmazie | pmid:22393833 |
Zarogoulidis P et al. | Macrolides: from in vitro anti-inflammatory and immunomodulatory properties to clinical practice in respiratory diseases. | 2012 | Eur. J. Clin. Pharmacol. | pmid:22105373 |
Bruin JP et al. | Wild-type MIC distribution and epidemiological cut-off values in clinical Legionella pneumophila serogroup 1 isolates. | 2012 | Diagn. Microbiol. Infect. Dis. | pmid:22100012 |
van Ingen J et al. | Drug susceptibility testing and pharmacokinetics question current treatment regimens in Mycobacterium simiae complex disease. | 2012 | Int. J. Antimicrob. Agents | pmid:22099521 |
Patel N and Miller CD | New option for management of HIV-1 infection in treatment-naive patients: once-daily, fixed-dose combination of rilpivirine-emtricitabine-tenofovir. | 2012 | HIV AIDS (Auckl) | pmid:22570576 |
Bondon-Guitton E et al. | Drug-induced gingival overgrowth: a study in the French Pharmacovigilance Database. | 2012 | J. Clin. Periodontol. | pmid:22519416 |
Vazquez-Lago JM et al. | Attitudes of primary care physicians to the prescribing of antibiotics and antimicrobial resistance: a qualitative study from Spain. | 2012 | Fam Pract | pmid:22016323 |
Diacon AH et al. | Randomized pilot trial of eight weeks of bedaquiline (TMC207) treatment for multidrug-resistant tuberculosis: long-term outcome, tolerability, and effect on emergence of drug resistance. | 2012 | Antimicrob. Agents Chemother. | pmid:22391540 |
Fujita J and Cash HL | Long-term combination treatment of azithromycin with other macrolides: a new era. | 2012 | Intern. Med. | pmid:22687831 |
Yamamoto Y et al. | A case of refractory chronic respiratory tract infection due to Pseudomonas aeruginosa successfully controlled by combination of clarithromycin and azithromycin. | 2012 | Intern. Med. | pmid:22687847 |
Sezikli M et al. | Supplementing vitamins C and E to standard triple therapy for the eradication of Helicobacter pylori. | 2012 | J Clin Pharm Ther | pmid:21740452 |
Cetin M et al. | Clarithromycin-Induced Long QT Syndrome: A Case Report. | 2012 | Case Rep Med | pmid:22489247 |
Amin M et al. | Green synthesis of silver nanoparticles through reduction with Solanum xanthocarpum L. berry extract: characterization, antimicrobial and urease inhibitory activities against Helicobacter pylori. | 2012 | Int J Mol Sci | pmid:22949839 |
Kwan BY and Rabheru K | Manic episode associated with clarithromycin in a patient with medically treated depression. | 2012 | Prim Care Companion CNS Disord | pmid:22943025 |
Cheung JP et al. | Mycobacterium marinum infection of the hand and wrist. | 2012 | J Orthop Surg (Hong Kong) | pmid:22933682 |
Zong W et al. | The first case of cutaneous infection with Mycobacterium parascrofulaceum. | 2012 | Ther Clin Risk Manag | pmid:22930638 |
D'Elios MM et al. | Helicobacter pylori: usefulness of an empirical fourth-line rifabutin-based regimen. | 2012 | Expert Rev Gastroenterol Hepatol | pmid:22928895 |
Wu TS et al. | Fish tank granuloma caused by Mycobacterium marinum. | 2012 | PLoS ONE | pmid:22911774 |
Ikegame S et al. | Congenital cystic adenomatoid malformation in adulthood complicated by Mycobacterium celatum infection. | 2012 | Intern. Med. | pmid:22892504 |
Jang YJ et al. | Maxillary sinus hypoplasia with a patent ostiomeatal complex: A therapeutic dilemma. | 2012 | Auris Nasus Larynx | pmid:21571467 |
Kido T et al. | Two cases of primary ciliary dyskinesia with different responses to macrolide treatment. | 2012 | Intern. Med. | pmid:22576394 |
Hansomburana P et al. | Prevalence of single nucleotide mutation in clarithromycin resistant gene of Helicobacter pylori: a 32-months prospective study by using hybridization real time polymerase chain reaction. | 2012 | J Med Assoc Thai | pmid:22619884 |
Rimbara E et al. | Molecular epidemiologic analysis and antimicrobial resistance of Helicobacter cinaedi isolated from seven hospitals in Japan. | 2012 | J. Clin. Microbiol. | pmid:22593597 |
Kant S et al. | Extra-pulmonary primary multidrug-resistant tubercular lymphadenitis in an HIV negative patient. | 2012 | BMJ Case Rep | pmid:22605844 |
Korkmaz S et al. | Unusual manifestations of acute Q fever: autoimmune hemolytic anemia and tubulointerstitial nephritis. | 2012 | Ann. Clin. Microbiol. Antimicrob. | pmid:22607576 |
Oh HS et al. | Ten-day sequential therapy is more effective than proton pump inhibitor-based therapy in Korea: a prospective, randomized study. | 2012 | J. Gastroenterol. Hepatol. | pmid:21916989 |
Suzuki H et al. | Molecular approaches and modern clinical strategies for the management of Helicobacter pylori infection in Japan. | 2012 | Keio J Med | pmid:23324305 |
Wong BC et al. | Effects of selective COX-2 inhibitor and Helicobacter pylori eradication on precancerous gastric lesions. | 2012 | Gut | pmid:21917649 |
Kim BJ et al. | Discovery of a novel hsp65 genotype within Mycobacterium massiliense associated with the rough colony morphology. | 2012 | PLoS ONE | pmid:22693637 |
Karczewska E et al. | Variability in Prevalence of Helicobacter pylori Strains Resistant to Clarithromycin and Levofloxacin in Southern Poland. | 2012 | Gastroenterol Res Pract | pmid:22693490 |
Tuchman SA et al. | Lenalidomide before and after Autologous Hematopoietic Stem Cell Transplantation in Multiple Myeloma. | 2012 | Adv Hematol | pmid:22690220 |
Ojetti V et al. | Impact of Lactobacillus reuteri Supplementation on Anti-Helicobacter pylori Levofloxacin-Based Second-Line Therapy. | 2012 | Gastroenterol Res Pract | pmid:22690211 |
Uno K et al. | Rupture of renal mycotic aneurysm that developed during the treatment of streptococcal infective endocarditis and vertebral osteomyelitis. | 2012 | Intern. Med. | pmid:22687800 |
Ogoshi T et al. | A case of Good syndrome with pulmonary lesions similar to diffuse panbronchiolitis. | 2012 | Intern. Med. | pmid:22576393 |
Tseng CH | Diabetes, insulin use and Helicobacter pylori eradication: a retrospective cohort study. | 2012 | BMC Gastroenterol | pmid:22571603 |
Park SK et al. | Regression of Advanced Gastric MALT Lymphoma after the Eradication of Helicobacter pylori. | 2012 | Gut Liver | pmid:22570759 |
Liang JH et al. | Structure-activity relationships of novel alkylides: 3-O-arylalkyl clarithromycin derivatives with improved antibacterial activities. | 2012 | Eur J Med Chem | pmid:22301216 |
Ankomah P and Levin BR | Two-drug antimicrobial chemotherapy: a mathematical model and experiments with Mycobacterium marinum. | 2012 | PLoS Pathog. | pmid:22253599 |
Lembo G et al. | Successful treatment of Mycobacterium terrae complex infection of the knee. | 2012 | J Clin Rheumatol | pmid:23047536 |
Melter O et al. | Bartonella quintana transmission from mite to family with high socioeconomic status. | 2012 | Emerging Infect. Dis. | pmid:22257438 |
Kjoller E et al. | Good interobserver agreement was attainable on outcome adjudication in patients with stable coronary heart disease. | 2012 | J Clin Epidemiol | pmid:22257841 |
Suzuki T | Meibomitis-related keratoconjunctivitis: implications and clinical significance of meibomian gland inflammation. | 2012 | Cornea | pmid:23038034 |
Kamada T et al. | [Case of acute pharyngitis caused by Corynebacterium ulcerans in Ibaraki Prefecture]. | 2012 | Nippon Jibiinkoka Gakkai Kaiho | pmid:22991854 |
Godreuil S et al. | Mycobacterium riyadhense pulmonary infection, France and Bahrain. | 2012 | Emerging Infect. Dis. | pmid:22261434 |
Nakajima S et al. | Multiple-antibiotic-resistant Helicobacter pylori infection eradicated with a tailor-made quadruple therapy. | 2012 | J. Gastroenterol. Hepatol. | pmid:22486882 |
Pasqualetti G et al. | Clarithromycin-induced rhabdomyolysis: a case report. | 2012 | Int J Gen Med | pmid:22505827 |
Sachs G and Scott DR | Helicobacter pylori: Eradication or Preservation. | 2012 | F1000 Med Rep | pmid:22500191 |
Bataille S et al. | Vancomycin-induced Henoch-Schönlein purpura: a case report. | 2012 | J Med Case Rep | pmid:22490390 |
Buyck JM et al. | Increased susceptibility of Pseudomonas aeruginosa to macrolides and ketolides in eukaryotic cell culture media and biological fluids due to decreased expression of oprM and increased outer-membrane permeability. | 2012 | Clin. Infect. Dis. | pmid:22573850 |
Shimizu T and Shimizu S | Azithromycin inhibits mucus hypersecretion from airway epithelial cells. | 2012 | Mediators Inflamm. | pmid:22577246 |
Kargar M et al. | Real-time PCR for Helicobacter pylori quantification and detection of clarithromycin resistance in gastric tissue from patients with gastrointestinal disorders. | 2012 | Res. Microbiol. | pmid:22177975 |
Mégraud F | The challenge of Helicobacter pylori resistance to antibiotics: the comeback of bismuth-based quadruple therapy. | 2012 | Therap Adv Gastroenterol | pmid:22423259 |
Srivastav NC et al. | Antimycobacterial activities of 5-alkyl (or halo)-3'-substituted pyrimidine nucleoside analogs. | 2012 | Bioorg. Med. Chem. Lett. | pmid:22178557 |
Scheel AH et al. | Talcum induced pneumoconiosis following inhalation of adulterated marijuana, a case report. | 2012 | Diagn Pathol | pmid:22420484 |
Ishii H et al. | Clarithromycin has limited effects in non-elderly, non-severe patients with seasonal influenza virus A infection. | 2012 | J. Infect. | pmid:22178990 |
Brüning J et al. | Erythromycin A dimethyl sulfoxide disolvate 1.43-hydrate. | 2012 | Acta Crystallogr Sect E Struct Rep Online | pmid:22412590 |
Aoyama N et al. | Clarithromycin suppresses the periodontal bacteria-accelerated abdominal aortic aneurysms in mice. | 2012 | J. Periodont. Res. | pmid:22181324 |
Noguchi S et al. | Clarithromycin monohydrate: a synchrotron X-ray powder study. | 2012 | Acta Crystallogr Sect E Struct Rep Online | pmid:22412567 |
Slany M et al. | Mycobacterium marinum infections in humans and tracing of its possible environmental sources. | 2012 | Can. J. Microbiol. | pmid:22182182 |
Karne SS et al. | Mycobacterium avium-intracellulare brain abscess in HIV-positive patient. | 2012 | Ann Indian Acad Neurol | pmid:22412276 |
Yanai A et al. | Non-bismuth quadruple therapy for first-line Helicobacter pylori eradication: A randomized study in Japan. | 2012 | World J Gastrointest Pharmacol Ther | pmid:22408744 |
Carella AM et al. | Clarithromycin potentiates tyrosine kinase inhibitor treatment in patients with resistant chronic myeloid leukemia. | 2012 | Leuk. Lymphoma | pmid:22233113 |
Yeboah J and Sharma OP | Co-existence of Crohn's disease, sarcoidosis and malignant lymphomas. | 2012 | JRSM Short Rep | pmid:22393471 |
Jakopović IP et al. | Novel desosamine-modified 14- and 15-membered macrolides without antibacterial activity. | 2012 | Bioorg. Med. Chem. Lett. | pmid:22503348 |
Siqueira JF et al. | Pyrosequencing as a tool for better understanding of human microbiomes. | 2012 | J Oral Microbiol | pmid:22279602 |
O'Brien DP et al. | Successful outcomes with oral fluoroquinolones combined with rifampicin in the treatment of Mycobacterium ulcerans: an observational cohort study. | 2012 | PLoS Negl Trop Dis | pmid:22272368 |
Lopes R et al. | [Antibiomania: a case of a manic episode induced by clarithromycin]. | 2011 Sep-Oct | Acta Med Port | pmid:22525636 |
Yasar KK et al. | Successfully treated Mycobacterium abscessus mastitis: a rare cause of breast masses. | 2011 Oct-Dec | Indian J Med Microbiol | pmid:22120809 |
Eisig JN et al. | Helicobacter pylori antibiotic resistance in Brazil: clarithromycin is still a good option. | 2011 Oct-Dec | Arq Gastroenterol | pmid:22147131 |
Abadi AT et al. | High frequency of A2143G mutation in clarithromycin-resistant Helicobacter pylori isolates recovered from dyspeptic patients in Iran. | 2011 Nov-Dec | Saudi J Gastroenterol | pmid:22064338 |
Bilgili SG et al. | Phototoxic dermatitis due to Chenopodium album in a child. | 2011 Nov-Dec | Pediatr Dermatol | pmid:21854411 |
Lee CY et al. | Digoxin toxicity precipitated by clarithromycin use: case presentation and concise review of the literature. | 2011 Nov-Dec | Can J Cardiol | pmid:21907534 |
Zeng M et al. | Comparison of efficacy of mometasone furoate versus clarithromycin in the treatment of chronic rhinosinusitis without nasal polyps in Chinese adults. | 2011 Nov-Dec | Am J Rhinol Allergy | pmid:22185725 |
Mello CF and Negra MD | Impact of macrolide therapy on mortality of HIV-infected patients with community-acquired pneumonia in a tertiary teaching hospital. | 2011 May-Jun | Braz J Infect Dis | pmid:21670928 |
Schmidt D | [The choice of treatment in HP associated ulcer: metronidazole or amoxicillin--nothing else!]. | 2011 May 4-10 | Lakartidningen | pmid:21809531 |
Steyaert S et al. | Soft tissue infections with atypical mycobacteria in two patients with inflammatory rheumatic diseases using TNF-inhibitors and/or leflunomide. | 2011 Mar-Apr | Acta Clin Belg | pmid:21630616 |
Söderberg KC and Böttiger Y | [Difficult choice between clarithromycin and metronidazole in polyneuropathy]. | 2011 Mar 9-15 | Lakartidningen | pmid:21744557 |
Chung JW et al. | The trends of one-week first-line and second-line eradication therapy for Helicobacter pylori infection in Korea. | 2011 Jan-Feb | Hepatogastroenterology | pmid:21510323 |
Galmés-Truyols A et al. | An outbreak of cutaneous infection due to Mycobacterium abscessus associated to mesotherapy. | 2011 Aug-Sep | Enferm. Infecc. Microbiol. Clin. | pmid:21684045 |
Castro-Silva AN et al. | Cutaneous Mycobacterium haemophilum infection in a kidney transplant recipient after acupuncture treatment. | 2011 | Transpl Infect Dis | pmid:20534038 |
Ernst P et al. | Risk of herpes zoster in patients prescribed inhaled corticosteroids: a cohort study. | 2011 | BMC Pulm Med | pmid:22177425 |
Kim EY et al. | Treatment outcome of combination therapy including clarithromycin for Mycobacterium avium complex pulmonary disease. | 2011 | Korean J. Intern. Med. | pmid:21437163 |
Hügle T | Immunology of fibrotic lung disease: managing infections whilst preventing autoimmunity? | 2011 | J Inflamm Res | pmid:22096366 |
Francois F et al. | The effect of H. pylori eradication on meal-associated changes in plasma ghrelin and leptin. | 2011 | BMC Gastroenterol | pmid:21489301 |
Atmatzidis S et al. | Clarithromycin modulates immune responses in experimental peritonitis. | 2011 | Int. J. Antimicrob. Agents | pmid:21353492 |
Hydzik P et al. | [Drug-induced erythrodermia complicated by multiorgan failure--case report]. | 2011 | Prz. Lek. | pmid:22010450 |
Green JS et al. | Persistent neutrophilic meningitis in an immunocompetent patient after basilar skull fracture: case report. | 2011 | BMC Infect. Dis. | pmid:21595944 |
Gamie Z et al. | Posterior reversible encephalopathy syndrome in a child with cyclical vomiting and hypertension: a case report. | 2011 | J Med Case Rep | pmid:21470405 |