clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with clarithromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (5)
- Drug Metab. Dispos. (1)
- FEMS Immunol. Med. Microbiol. (1)
- Others (5)
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Ellis LC et al. | Postantibiotic effect of clarithromycin alone and combined with ethambutol against Mycobacterium avium complex. | 1995 | Antimicrob. Agents Chemother. | pmid:8593025 |
| Truffot-Pernot C et al. | Clarithromycin is inactive against Mycobacterium tuberculosis. | 1995 | Antimicrob. Agents Chemother. | pmid:8593032 |
| Schütze K and Hentschel E | Duodenal ulcer healing after 7-day treatment: a pilot study with lansoprazole, amoxicillin and clarithromycin. | 1995 | Z Gastroenterol | pmid:8600661 |
| Stein GE et al. | A preliminary study of clarithromycin versus doxycycline in the treatment of nongonococcal urethritis and mucopurulent cervicitis. | 1995 Nov-Dec | Pharmacotherapy | pmid:8602379 |
| Torriani FJ et al. | Disseminated Mycobacterium avium complex: correlation between blood and tissue burden. | 1996 | J. Infect. Dis. | pmid:8603975 |
| Vakil N and Fennerty MB | Cost-effectiveness of treatment regimens for the eradication of Helicobacter pylori in duodenal ulcer. | 1996 | Am. J. Gastroenterol. | pmid:8607487 |
| Treiber G | The influence of drug dosage on Helicobacter pylori eradication: a cost-effectiveness analysis. | 1996 | Am. J. Gastroenterol. | pmid:8607488 |
| Shaheen N and Grimm IS | Fulminant hepatic failure associated with clarithromycin. | 1996 | Am. J. Gastroenterol. | pmid:8607519 |
| Horowitz RS et al. | Clinical ergotism with lingual ischemia induced by clarithromycin-ergotamine interaction. | 1996 | Arch. Intern. Med. | pmid:8607732 |
| Thompson D and Oster G | Use of terfenadine and contraindicated drugs. | 1996 | JAMA | pmid:8614120 |
| Dammann HG | Therapy with omeprazole and clarithromycin increases serum carbamazepine levels in patients with H. pylori gastritis. | 1996 | Dig. Dis. Sci. | pmid:8617126 |
| Atkinson BA et al. | Treatment of Mycobacterium haemophilum infection in a murine model with clarithromycin, rifabutin, and ciprofloxacin. | 1995 | Antimicrob. Agents Chemother. | pmid:8619588 |
| Nightingale SL | From the Food and Drug Administration. | 1996 May 22-29 | JAMA | pmid:8622234 |
| Meyboom RH et al. | [Possible potentiation of phenprocoumon by clarithromycin and roxithromycin]. | 1996 | Ned Tijdschr Geneeskd | pmid:8628425 |
| Sjöström JE and Larsson H | Factors affecting growth and antibiotic susceptibility of Helicobacter pylori: effect of pH and urea on the survival of a wild-type strain and a urease-deficient mutant. | 1996 | J. Med. Microbiol. | pmid:8636959 |
| Clarithromycin and omeprazole for Helicobacter pylori. | 1996 | Med Lett Drugs Ther | pmid:8637481 | |
| Asnis DS et al. | Mycobacterium avium-intracellulare complex pneumonia in a non-HIV-infected individual: an increasingly recognized disease. | 1996 | South. Med. J. | pmid:8638183 |
| Hunt RH | Eradication of Helicobacter pylori infection. | 1996 | Am. J. Med. | pmid:8644782 |
| Ford A et al. | Clarithromycin-induced digoxin toxicity in a patient with AIDS. | 1995 | Clin. Infect. Dis. | pmid:8645810 |
| Young LS | Treatment and prophylaxis of Mycobacterium avium complex. | 1996 | Int J STD AIDS | pmid:8652724 |
| McCutchan JA | Azithromycin in the prophylaxis of opportunistic infections in AIDS. | 1996 | Int J STD AIDS | pmid:8652726 |
| Blomgren K and Alván G | [New guidelines from the Medical Products Agency: the triple regime against Helicobacter pylori is necessary. Treat only if the ulcer is verified]. | 1996 | Lakartidningen | pmid:8656812 |
| Pierce M et al. | A randomized trial of clarithromycin as prophylaxis against disseminated Mycobacterium avium complex infection in patients with advanced acquired immunodeficiency syndrome. | 1996 | N. Engl. J. Med. | pmid:8663871 |
| Bates JH | Mycobacterium avium disease: progress at last. | 1996 | Am. J. Respir. Crit. Care Med. | pmid:8665029 |
| Wallace RJ et al. | Clarithromycin regimens for pulmonary Mycobacterium avium complex. The first 50 patients. | 1996 | Am. J. Respir. Crit. Care Med. | pmid:8665032 |
| Frothingham R | Clarithromycin treatment for Mycobacterium avium-intracellulare complex lung disease. | 1996 | Am. J. Respir. Crit. Care Med. | pmid:8665069 |
| Dalston MO et al. | [Clarithromycin combined with pyrimethamine in cerebral toxoplasmosis--a report of 2 cases]. | 1995 Oct-Dec | Rev. Soc. Bras. Med. Trop. | pmid:8668843 |
| Treille S et al. | Kidney graft dysfunction after drug interaction between clarithromycin and cyclosporin. | 1996 | Nephrol. Dial. Transplant. | pmid:8672003 |
| Rastogi N et al. | In vitro activities of fourteen antimicrobial agents against drug susceptible and resistant clinical isolates of Mycobacterium tuberculosis and comparative intracellular activities against the virulent H37Rv strain in human macrophages. | 1996 | Curr. Microbiol. | pmid:8672093 |
| Shafran SD et al. | A comparison of two regimens for the treatment of Mycobacterium avium complex bacteremia in AIDS: rifabutin, ethambutol, and clarithromycin versus rifampin, ethambutol, clofazimine, and ciprofloxacin. Canadian HIV Trials Network Protocol 010 Study Group. | 1996 | N. Engl. J. Med. | pmid:8676931 |
| Shimoyama T et al. | Validity of various diagnostic tests to evaluate cure of Helicobacter pylori infection. | 1996 | J. Gastroenterol. | pmid:8680535 |
| Sellal A et al. | [Maintenance treatment of cerebral toxoplasmosis in AIDS: role of clarithromycin-minocycline combination]. | 1996 | Presse Med | pmid:8685115 |
| Schouenborg P | [Clarithromycin]. | 1996 | Ugeskr. Laeg. | pmid:8686028 |
| Goddard AF et al. | Effect of omeprazole on the distribution of metronidazole, amoxicillin, and clarithromycin in human gastric juice. | 1996 | Gastroenterology | pmid:8690200 |
| Lambert JR | Pharmacology of the gastric mucosa: a rational approach to Helicobacter polytherapy. | 1996 | Gastroenterology | pmid:8690219 |
| MacConnachie AM | Clarithromycin (klaricid, Abbott). | 1996 | Intensive Crit Care Nurs | pmid:8696027 |
| Meier A et al. | Molecular mechanisms of clarithromycin resistance in Mycobacterium avium: observation of multiple 23S rDNA mutations in a clonal population. | 1996 | J. Infect. Dis. | pmid:8699066 |
| Araki J et al. | [A case of Mounier-Kuhn syndrome]. | 1996 | Nippon Naika Gakkai Zasshi | pmid:8708483 |
| Lowe SH et al. | Uveitis during treatment of disseminated Mycobacterium avium-intracellulare complex infection with the combination of rifabutin, clarithromycin and ethambutol. | 1996 | Neth J Med | pmid:8710040 |
| Unge P | Review of Helicobacter pylori eradication regimens. | 1996 | Scand. J. Gastroenterol. Suppl. | pmid:8722388 |
| Bazzoli F | Italian omeprazole triple therapy--a 1-week regimen. | 1996 | Scand. J. Gastroenterol. Suppl. | pmid:8722395 |
| Goddard AF and Logan RP | Antimicrobial resistance and Helicobacter pylori. | 1996 | J. Antimicrob. Chemother. | pmid:8722530 |
| Barry AL et al. | Reassessment of methods for testing the susceptibility of Haemophilus influenzae to clarithromycin. | 1996 | J. Antimicrob. Chemother. | pmid:8722555 |
| H. pylori treatment recognized by FDA. | 1996 | Am J Health Syst Pharm | pmid:8725200 | |
| Morikawa K et al. | Modulatory effect of antibiotics on cytokine production by human monocytes in vitro. | 1996 | Antimicrob. Agents Chemother. | pmid:8726002 |
| Arain TM et al. | Bioluminescence screening in vitro (Bio-Siv) assays for high-volume antimycobacterial drug discovery. | 1996 | Antimicrob. Agents Chemother. | pmid:8726034 |
| Mertl SL | The role of clarithromycin in the prophylaxis of disseminated Mycobacterium avium-intracellulare infection in patients with AIDS. | 1996 May-Jun | Pharmacotherapy | pmid:8726597 |
| Vasquez A et al. | Metronidazole and clarithromycin resistance in Helicobacter pylori determined by measuring MICs of antimicrobial agents in color indicator egg yolk agar in a miniwell format. The Gastrointestinal Physiology Working Group of Universidad Peruana Cayetano Heredia and the Johns Hopkins University. | 1996 | J. Clin. Microbiol. | pmid:8727909 |
| Darouiche RO et al. | Recurrent disseminated infection with Mycobacterium avium complex identified in tissues by molecular analysis. | 1996 | Clin. Infect. Dis. | pmid:8729215 |
| Gillum JG et al. | Effect of clarithromycin on the pharmacokinetics of 2',3'-dideoxyinosine in patients who are seropositive for human immunodeficiency virus. | 1996 | Clin. Infect. Dis. | pmid:8729217 |
| Dalla Libera M et al. | High effectiveness and safety of one-week antibiotic regimen in Helicobacter pylori eradication. | 1996 | Aliment. Pharmacol. Ther. | pmid:8730251 |
| Labenz J et al. | One-week triple therapy with omeprazole, amoxycillin and either clarithromycin or metronidazole for cure of Helicobacter pylori infection. | 1996 | Aliment. Pharmacol. Ther. | pmid:8730252 |
| Bachelez H et al. | Disseminated varioliform pustular eruption due to Mycobacterium avium intracellulare in an HIV-infected patient. | 1996 | Br. J. Dermatol. | pmid:8733397 |
| Heifets LB | Clarithromycin against Mycobacterium avium complex infections. | 1996 | Tuber. Lung Dis. | pmid:8733409 |
| Deltenre M et al. | [How to eradicate Helicobacter pylori in 1995? Critical review of available treatments]. | 1996 | Gastroenterol. Clin. Biol. | pmid:8734370 |
| Cayla R | [How to eradicate Helicobacter pylori?]. | 1996 | Gastroenterol. Clin. Biol. | pmid:8734380 |
| Koga T et al. | In-vitro and in-vivo antibacterial activity of plaunotol, a cytoprotective antiulcer agent, against Helicobacter pylori. | 1996 | J. Antimicrob. Chemother. | pmid:8737142 |
| Lebrun L et al. | Evaluation of the Etest for rapid susceptibility testing of Mycobacterium avium to clarithromycin. | 1996 | J. Antimicrob. Chemother. | pmid:8737150 |
| Akamatsu H et al. | Enhanced effect of clarithromycin on neutrophil function in vitro. | 1996 Mar-Apr | J. Int. Med. Res. | pmid:8737228 |
| Markham A and McTavish D | Clarithromycin and omeprazole as helicobacter pylori eradication therapy in patients with H. pylori-associated gastric disorders. | 1996 | Drugs | pmid:8741237 |
| Sternon J et al. | Azithromycin compared with clarithromycin in the treatment of adult patients with acute purulent tracheobronchitis: a cost of illness study. | 1995 Nov-Dec | J. Int. Med. Res. | pmid:8746608 |
| Santander C et al. | Antimicrobial therapy for Helicobacter pylori infection versus long-term maintenance antisecretion treatment in the prevention of recurrent hemorrhage from peptic ulcer: prospective nonrandomized trial on 125 patients. | 1996 | Am. J. Gastroenterol. | pmid:8759659 |
| Tursi A et al. | Short-term low-dose triple therapy with lansoprazole plus amoxycillin and clarithromycin for Helicobacter pylori eradication. | 1996 | Am. J. Gastroenterol. | pmid:8759696 |
| Debets-Ossenkopp YJ et al. | Mechanism of clarithromycin resistance in clinical isolates of Helicobacter pylori. | 1996 | FEMS Microbiol. Lett. | pmid:8759787 |
| Sander P et al. | Ribosomal drug resistance in mycobacteria. | 1996 Jan-Feb | Res. Microbiol. | pmid:8761724 |
| Géhanno P et al. | [Clarithromycin versus amoxicillin-clavulanic acid in the treatment of acute maxillary sinusitis in adults]. | 1996 | Pathol. Biol. | pmid:8763594 |
| Jordan WC | Clarithromycin prophylaxis against Cryptosporidium enteritis in patients with AIDS. | 1996 | J Natl Med Assoc | pmid:8764523 |
| Berger C et al. | Treatment of nontuberculous mycobacterial lymphadenitis with clarithromycin plus rifabutin. | 1996 | J. Pediatr. | pmid:8774511 |
| Sito E et al. | One week treatment with omeprazole, clarithromycin and tinidazole or lansoprazole, amoxicillin and metronidazole for cure of Helicobacter pylori infection in duodenal ulcer patients. | 1996 | J. Physiol. Pharmacol. | pmid:8777303 |
| Gabryelewicz A | Critical evaluation of the treatment of peptic ulcer diseases associated with Helicobacter pylori infection. | 1996 | J. Physiol. Pharmacol. | pmid:8777307 |
| Deltenre M et al. | Strategies for Helicobacter pylori eradication in 1995: a review of international and Belgian experience. | 1996 | J. Physiol. Pharmacol. | pmid:8777308 |
| Roesch W | Cost-effectiveness of H. pylori eradication. | 1996 | J. Physiol. Pharmacol. | pmid:8777309 |
| Apseloff G et al. | Severe neutropenia caused by recommended prophylactic doses of rifabutin. | 1996 | Lancet | pmid:8782773 |
| Plemmons RM et al. | Otitis media and mastoiditis due to Mycobacterium fortuitum: case report, review of four cases, and a cautionary note. | 1996 | Clin. Infect. Dis. | pmid:8783722 |
| Bagarazzi ML et al. | Pulmonary Mycobacterium gordonae infection in a two-year-old child: case report. | 1996 | Clin. Infect. Dis. | pmid:8783736 |
| Reid R et al. | Pneumococcal meningitis during therapy of otitis media with clarithromycin. | 1995 | Pediatr. Infect. Dis. J. | pmid:8786899 |
| Welsh L et al. | In vitro activities of azithromycin, clarithromycin, erythromycin, and tetracycline against 13 strains of Chlamydia pneumoniae. | 1996 | Antimicrob. Agents Chemother. | pmid:8787907 |
| Mehaffey PC et al. | Evaluation of in vitro spectra of activity of azithromycin, clarithromycin, and erythromycin tested against strains of Neisseria gonorrhoeae by reference agar dilution, disk diffusion, and Etest methods. | 1996 | J. Clin. Microbiol. | pmid:8789046 |
| Gross U and Pohl F | Influence of antimicrobial agents on replication and stage conversion of Toxoplasma gondii. | 1996 | Curr. Top. Microbiol. Immunol. | pmid:8791704 |
| Peterson WL et al. | Ranitidine bismuth citrate plus clarithromycin is effective for healing duodenal ulcers, eradicating H. pylori and reducing ulcer recurrence. RBC H. pylori Study Group. | 1996 | Aliment. Pharmacol. Ther. | pmid:8791947 |
| Delchier JC et al. | Omeprazole-amoxycillin versus omeprazole-amoxycillin-clarithromycin in the eradication of Helicobacter pylori. | 1996 | Aliment. Pharmacol. Ther. | pmid:8791948 |
| Jaup BH and Norrby A | Comparison of two low-dose one-week triple therapy regimens with and without metronidazole for cure of H. pylori infection. | 1996 | Aliment. Pharmacol. Ther. | pmid:8791950 |
| Weldon MJ et al. | A seven-day Helicobacter pylori treatment regimen using clarithromycin, omeprazole and tripotassium dicitrato bismuthate. | 1996 | Aliment. Pharmacol. Ther. | pmid:8791951 |
| Tursi A et al. | Low-dose omeprazole plus clarithromycin and either tinidazole or amoxycillin for Helicobacter pylori infection. | 1996 | Aliment. Pharmacol. Ther. | pmid:8791952 |
| Papp J et al. | Efficacy of nizatidine, clarithromycin and bismuth subcitrate therapy for Helicobacter pylori eradication in duodenal ulcer patients--a preliminary report. | 1996 Jul-Aug | Br J Clin Pract | pmid:8794601 |
| Goh KL et al. | Helicobacter pylori eradication with short-term therapy leads to duodenal ulcer healing without the need for continued acid suppression therapy. | 1996 | Eur J Gastroenterol Hepatol | pmid:8804868 |
| Conte JE et al. | Single-dose intrapulmonary pharmacokinetics of azithromycin, clarithromycin, ciprofloxacin, and cefuroxime in volunteer subjects. | 1996 | Antimicrob. Agents Chemother. | pmid:8807050 |
| Wallace RJ et al. | Genetic basis for clarithromycin resistance among isolates of Mycobacterium chelonae and Mycobacterium abscessus. | 1996 | Antimicrob. Agents Chemother. | pmid:8807061 |
| Gillum JG et al. | Effect of combination therapy with ciprofloxacin and clarithromycin on theophylline pharmacokinetics in healthy volunteers. | 1996 | Antimicrob. Agents Chemother. | pmid:8807068 |
| Nash KA and Inderlied CB | Rapid detection of mutations associated with macrolide resistance in Mycobacterium avium complex. | 1996 | Antimicrob. Agents Chemother. | pmid:8807078 |
| Sketris IS et al. | Possible role of the intestinal P-450 enzyme system in a cyclosporine-clarithromycin interaction. | 1996 Mar-Apr | Pharmacotherapy | pmid:8820476 |
| Nishi K et al. | [Effect of clarithromycin on symptoms and mucociliary transport in patients with sino-bronchial syndrome]. | 1995 | Nihon Kyobu Shikkan Gakkai Zasshi | pmid:8821993 |
| Xu G et al. | [Effect of clarithromycin on cytocidal activity against Pseudomonas aeruginosa in mice peritoneal cavity]. | 1996 | Kansenshogaku Zasshi | pmid:8822058 |
| Pijpers E et al. | A clarithromycin-induced myasthenic syndrome. | 1996 | Clin. Infect. Dis. | pmid:8824993 |
| Webb DD | Practice guidelines for treatment of peptic ulcer disease. | 1996 | JAMA | pmid:8827959 |
| Piersimoni C et al. | Activity of seven antimicrobial agents, alone and in combination, against AIDS-associated isolates of Mycobacterium avium complex. | 1995 | J. Antimicrob. Chemother. | pmid:8830013 |
| Erah PO et al. | Ion-pair high-performance liquid chromatographic assay method for the assessment of clarithromycin stability in aqueous solution and in gastric juice. | 1996 | J. Chromatogr. B, Biomed. Appl. | pmid:8832427 |
| Vangala R and Cernek PK | Hypersensitivity reaction to clarithromycin. | 1996 | Ann Pharmacother | pmid:8833572 |
| Ji B et al. | Bactericidal activities of combinations of new drugs against Mycobacterium leprae in nude mice. | 1996 | Antimicrob. Agents Chemother. | pmid:8834886 |
| Yamamoto T et al. | Activity of KRM-1648 alone or in combination with both ethambutol and kanamycin or clarithromycin against Mycobacterium intracellulare infections in beige mice. | 1996 | Antimicrob. Agents Chemother. | pmid:8834892 |