clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with clarithromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (5)
- Drug Metab. Dispos. (1)
- FEMS Immunol. Med. Microbiol. (1)
- Others (5)
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Domschke W | Omeprazole, Helicobacter pylori, and gastritis. | 1994 | J. Gastroenterol. | pmid:7921141 |
| Geraci AJ | Empiric antibiotics in sinusitis. | 1994 | Arch Fam Med | pmid:7921288 |
| Rust GS | Multicenter comparison of clarithromycin and amoxicillin. | 1994 | Arch Fam Med | pmid:7921290 |
| Sieber CC et al. | [Helicobacter pylori resistance against metronidazole in Switzerland: implications for eradication therapy?]. | 1994 | Schweiz Med Wochenschr | pmid:8091165 |
| Terashima T et al. | Pulmonary infection due to Mycobacterium xenopi. | 1994 | Intern. Med. | pmid:8000103 |
| Dorrell L et al. | Toxicity of clarithromycin in the treatment of Mycobacterium avium complex infection in a patient with AIDS. | 1994 | J. Antimicrob. Chemother. | pmid:7868416 |
| Fish DN et al. | Penetration of clarithromycin into lung tissues from patients undergoing lung resection. | 1994 | Antimicrob. Agents Chemother. | pmid:8031063 |
| Funke G et al. | Development of resistance to macrolide antibiotics in an AIDS patient treated with clarithromycin for Campylobacter jejuni diarrhea. | 1994 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:7805694 |
| Fujii R et al. | [Clinical studies on clarithromycin dry syrup in the pediatric field. Pediatric Study Group of TE-031 Dry Syrup]. | 1994 | Jpn J Antibiot | pmid:7807690 |
| Bonnet E et al. | Clarithromycin: a potent agent against infections due to Mycobacterium marinum. | 1994 | Clin. Infect. Dis. | pmid:8038339 |
| Lemmen SW et al. | Bactericidal activity of clarithromycin and cefaclor against Streptococcus pneumoniae and Moraxella catarrhalis in healthy volunteers. | 1994 | J. Antimicrob. Chemother. | pmid:8040139 |
| Dautzenberg B et al. | [Treatment with clarithromycin of 173 HIV+ patients with disseminated Mycobacterium avium intracellulare infection]. | 1994 | Rev Mal Respir | pmid:8041990 |
| Böttger EC | Resistance to drugs targeting protein synthesis in mycobacteria. | 1994 | Trends Microbiol. | pmid:7850212 |
| al-Assi MT et al. | Clarithromycin, tetracycline, and bismuth: a new non-metronidazole therapy for Helicobacter pylori infection. | 1994 | Am. J. Gastroenterol. | pmid:8053435 |
| Guelar A et al. | [Therapeutic alternatives for cases of cerebral toxoplasmosis in patients with AIDS: clarithromycin and atovaquone]. | 1994 | Enferm. Infecc. Microbiol. Clin. | pmid:8011719 |
| Aspin MM et al. | Comparative study of the safety and efficacy of clarithromycin and amoxicillin-clavulanate in the treatment of acute otitis media in children. | 1994 | J. Pediatr. | pmid:8021763 |
| Thijs JC et al. | Short report: clarithromycin, an alternative to metronidazole in the triple therapy of Helicobacter pylori infection. | 1994 | Aliment. Pharmacol. Ther. | pmid:8186339 |
| Logan RP et al. | Eradication of Helicobacter pylori with clarithromycin and omeprazole. | 1994 | Gut | pmid:8150340 |
| Honeybourne D et al. | The levels of clarithromycin and its 14-hydroxy metabolite in the lung. | 1994 | Eur. Respir. J. | pmid:7925906 |
| Morikawa K et al. | Immunomodulatory effects of three macrolides, midecamycin acetate, josamycin, and clarithromycin, on human T-lymphocyte function in vitro. | 1994 | Antimicrob. Agents Chemother. | pmid:7532933 |
| Shafran SD et al. | Uveitis and pseudojaundice during a regimen of clarithromycin, rifabutin, and ethambutol. MAC Study Group of the Canadian HIV Trials Network. | 1994 | N. Engl. J. Med. | pmid:8284019 |
| Roblin PM et al. | Susceptibilities to clarithromycin and erythromycin of isolates of Chlamydia pneumoniae from children with pneumonia. | 1994 | Antimicrob. Agents Chemother. | pmid:7979292 |
| Meier A et al. | Identification of mutations in 23S rRNA gene of clarithromycin-resistant Mycobacterium intracellulare. | 1994 | Antimicrob. Agents Chemother. | pmid:8192472 |
| Labenz J et al. | [Omeprazole modified antibiotic therapy of Helicobacter pylori infection: can clarithromycin be replaced by roxithromycin?]. | 1994 | Leber Magen Darm | pmid:8196468 |
| Chan GP et al. | Clinical trial of clarithromycin for lepromatous leprosy. | 1994 | Antimicrob. Agents Chemother. | pmid:8203847 |
| [Recent advances in macrolide antibiotics: focused on clarithromycin. Discussion]. | 1994 | Jpn J Antibiot | pmid:7990251 | |
| Onyeji CO et al. | Efficacies of liposome-encapsulated clarithromycin and ofloxacin against Mycobacterium avium-M. intracellulare complex in human macrophages. | 1994 | Antimicrob. Agents Chemother. | pmid:8203849 |
| Tsang KW et al. | The concentrations of clarithromycin and its 14-hydroxy metabolite in sputum of patients with bronchiectasis following single dose oral administration. | 1994 | J. Antimicrob. Chemother. | pmid:8182010 |
| Sundberg L and Cederberg A | Penetration of clarithromycin and its 14-hydroxy metabolite into middle ear effusion in children with secretory otitis media. | 1994 | J. Antimicrob. Chemother. | pmid:8182011 |
| [Zeclar, a new antibiotic (clarithromycin 250 mg from Abbott laboratories]. | 1994 | Rev Infirm | pmid:7652424 | |
| Olliaro P et al. | In-vitro and in-vivo activity of rifabutin against Toxoplasma gondii. | 1994 | J. Antimicrob. Chemother. | pmid:7706160 |
| Cynamon MH et al. | Comparative activities of azithromycin and clarithromycin against Mycobacterium avium infection in beige mice. | 1994 | Antimicrob. Agents Chemother. | pmid:7979270 |
| Marco ML et al. | [Rhodococcus equi pneumonia in patients with AIDS]. | 1994 | Arch. Bronconeumol. | pmid:7827773 |
| Laing RB et al. | New antimicrobials against Mycobacterium marinum infection. | 1994 | Br. J. Dermatol. | pmid:7857853 |
| Spiegl PV and Feiner CM | Mycobacterium phlei infection of the foot: a case report. | 1994 | Foot Ankle Int | pmid:7894643 |
| Rapp RP et al. | New macrolide antibiotics: usefulness in infections caused by mycobacteria other than Mycobacterium tuberculosis. | 1994 | Ann Pharmacother | pmid:7849341 |
| Walker KJ et al. | Evaluation of antimicrobial activities of clarithromycin and 14-hydroxyclarithromycin against three strains of Haemophilus influenzae by using an in vitro pharmacodynamic model. | 1994 | Antimicrob. Agents Chemother. | pmid:7811010 |
| Price DA et al. | Clinical response to the addition of clarithromycin in Pneumocystis carinii pneumonia refractory to high dose co-trimoxazole. | 1994 | J. Antimicrob. Chemother. | pmid:7814298 |
| Tahara RW et al. | The question of clarithromycin: a first-line drug for sinusitis? | 1994 | Arch Fam Med | pmid:7818657 |
| Pustorino S et al. | [Effects of intravenous administration of clarithromycin on plasma levels of gastrin and group I pepsinogen]. | 1994 | Clin Ter | pmid:7820984 |
| Alder J et al. | Treatment of experimental Toxoplasma gondii infection by clarithromycin-based combination therapy with minocycline or pyrimethamine. | 1994 | J. Acquir. Immune Defic. Syndr. | pmid:7932081 |
| Ferrari SL et al. | The interaction between clarithromycin and cyclosporine in kidney transplant recipients. | 1994 | Transplantation | pmid:7940695 |
| Tomono K | [Therapeutic efficacy of macrolide in pulmonary nontuberculous mycobacteriosis]. | 1994 | Kekkaku | pmid:7837727 |
| Sanchez T et al. | Quantitation of mycobacteria in blood specimens from patients with AIDS. | 1994 | Tuber. Lung Dis. | pmid:7841433 |
| Sungur C | Acute rheumatic fever despite clarithromycin treatment of beta-hemolytic streptococcal tonsillitis. | 1994 | Ann Pharmacother | pmid:7841580 |
| Maass M and Dalhoff K | [Isolation of Chlamydia pneumoniae in atypical pneumonia]. | 1994 | Dtsch. Med. Wochenschr. | pmid:7956770 |
| Verbist L and Dhoore F | In vitro susceptibility of recently isolated respiratory tract pathogens to minocycline and comparable antibiotics. A multicentre study. | 1994 | Acta Clin Belg | pmid:7871933 |
| Ji B et al. | Effectiveness of various antimicrobial agents against Mycobacterium avium complex in the beige mouse model. | 1994 | Antimicrob. Agents Chemother. | pmid:7872741 |
| Skinner PS et al. | A bone marrow-derived murine macrophage model for evaluating efficacy of antimycobacterial drugs under relevant physiological conditions. | 1994 | Antimicrob. Agents Chemother. | pmid:7872747 |
| Valero G et al. | Activities of clarithromycin, ofloxacin, and clarithromycin plus ethambutol against Mycobacterium simiae in murine model of disseminated infection. | 1994 | Antimicrob. Agents Chemother. | pmid:7872769 |