clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with clarithromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Model | Cross reference | Weighted score | Related literatures |
---|
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Auw-Hädrich C et al. | [Clarithromycin for monotherapy of B-cell MALT lymphoma?]. | 2013 | Ophthalmologe | pmid:24231914 |
Rezvanian E and Watson NF | Kleine-levin syndrome treated with clarithromycin. | 2013 | J Clin Sleep Med | pmid:24235906 |
Cosme A et al. | Usefulness of antimicrobial susceptibility in the eradication of Helicobacter pylori. | 2013 | Clin. Microbiol. Infect. | pmid:22512623 |
Srivastava S et al. | Therapeutic drug management: is it the future of multidrug-resistant tuberculosis treatment? | 2013 | Eur. Respir. J. | pmid:24293417 |
Gui J et al. | [Drug sensitivity analysis of Mycobacterium chelonae and Mycobacterium abscessus and evaluation of Etest for susceptibility testing]. | 2013 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:24252731 |
Formanoy E et al. | Tenosynovitis of the right hand. Mycobacterium kansasii. | 2013 | Neth J Med | pmid:24394739 |
Chen K et al. | Low dose macrolide administration for long term is effective for otitis media with effusion in children. | 2013 | Auris Nasus Larynx | pmid:22673738 |
Herath SC and Poole P | Prophylactic antibiotic therapy for chronic obstructive pulmonary disease (COPD). | 2013 | Cochrane Database Syst Rev | pmid:24288145 |
Zhu D et al. | Synthesis of 4″-O-desosaminyl clarithromycin derivatives and their anti-bacterial activities. | 2013 | Bioorg. Med. Chem. Lett. | pmid:24139585 |
Nasa M et al. | Sequential therapy versus standard triple-drug therapy for Helicobacter pylori eradication: a randomized study. | 2013 | Indian J Gastroenterol | pmid:24158898 |
Kim SY et al. | Comparative study of Helicobacter pylori eradication rates with 5-day quadruple "concomitant" therapy and 7-day standard triple therapy. | 2013 | J. Clin. Gastroenterol. | pmid:22647826 |
Fagoonee S et al. | Efficacy of cefixime-based triple therapy for Helicobacter pylori eradication: a retrospective study. | 2013 | Panminerva Med | pmid:24088806 |
Gisbert JP et al. | Second-line therapy with levofloxacin after failure of treatment to eradicate helicobacter pylori infection: time trends in a Spanish Multicenter Study of 1000 patients. | 2013 | J. Clin. Gastroenterol. | pmid:22647827 |
Piso RJ et al. | Coverage of atypical pathogens for hospitalised patients with community-acquired pneumonia is not guided by clinical parameters. | 2013 | Swiss Med Wkly | pmid:24089030 |
Schafranek L et al. | Clarithromycin enhances dasatinib-induced cell death in chronic myeloid leukemia cells, by inhibition of late stage autophagy. | 2013 | Leuk. Lymphoma | pmid:22656271 |
Yonezawa H et al. | Impact of Helicobacter pylori biofilm formation on clarithromycin susceptibility and generation of resistance mutations. | 2013 | PLoS ONE | pmid:24039906 |
Gysel M et al. | Torsades de pointes following clarithromycin treatment. | 2013 | Expert Rev Cardiovasc Ther | pmid:24147515 |
Megraud F et al. | Helicobacter pylori resistance to antibiotics in Europe and its relationship to antibiotic consumption. | 2013 | Gut | pmid:22580412 |
[Clarithromycin therapy for patients with cystic fibrosis: a randomized controlled trial]. | 2013 | Jpn J Antibiot | pmid:24930240 | |
Wang S et al. | A supra-monolayer nanopattern for organic nanoparticle array deposition. | 2013 | ACS Appl Mater Interfaces | pmid:23480527 |
Morse AL et al. | A randomized controlled trial comparing sequential with triple therapy for Helicobacter pylori in an Aboriginal community in the Canadian North. | 2013 | Can. J. Gastroenterol. | pmid:24340314 |
Pan W et al. | Effects of clopidogrel and clarithromycin on the disposition of sibutramine and its active metabolites M1 and M2 in relation to CYP2B6*6 polymorphism. | 2013 | Xenobiotica | pmid:22830954 |
Schmidt BJ and Hermansen MN | [Late debut of neonatal pneumonia caused by Chlamydia trachomatis]. | 2013 | Ugeskr. Laeg. | pmid:23428270 |
Tsukanov VV et al. | [Helicobacter pylori eradication: current status]. | 2013 | Ter. Arkh. | pmid:23653944 |
Sierra F et al. | Pilot study: miscellaneous therapy is highly successful for Helicobacter pylori eradication. | 2013 | Aliment. Pharmacol. Ther. | pmid:23656465 |
Radouane N et al. | [Generalized chromomycosis caused by Phialophora verrucosa]. | 2013 | Ann Dermatol Venereol | pmid:23466152 |
Otsuka SH | Severe hypoglycemia from Helicobacter pylori triple-drug therapy and insulin detemir drug interaction. | 2013 | Pharmacotherapy | pmid:23471710 |
Jiang JW et al. | Synthesis and antibacterial evaluation of a novel series of 10-hydroxyl ketolide derivatives. | 2013 | Bioorg. Med. Chem. Lett. | pmid:23591116 |
Odagiri T et al. | Design, synthesis, and biological evaluations of novel 7-[7-amino-7-methyl-5-azaspiro[2.4]heptan-5-yl]-8-methoxyquinolines with potent antibacterial activity against respiratory pathogens. | 2013 | J. Med. Chem. | pmid:23409972 |
Haas K | [Reply]. | 2013 | Ophthalmologe | pmid:24377112 |
Kale-Pradhan PB et al. | The role of antimicrobials in Crohn's disease. | 2013 | Expert Rev Gastroenterol Hepatol | pmid:23445237 |
Pasipanodya JG and Gumbo T | Drug concentration monitoring in Mycobacterium avium lung disease: problems with methods and conclusions. | 2013 | Am. J. Respir. Crit. Care Med. | pmid:23457368 |
Sasaki H et al. | Ten-year trend of the cumulative Helicobacter pylori eradication rate for the 'Japanese eradication strategy'. | 2013 | Digestion | pmid:24356705 |
Yakoob J et al. | Low rate of recurrence of Helicobacter pylori infection in spite of high clarithromycin resistance in Pakistan. | 2013 | BMC Gastroenterol | pmid:23433429 |
Yuan Y et al. | Optimum duration of regimens for Helicobacter pylori eradication. | 2013 | Cochrane Database Syst Rev | pmid:24338763 |
Amin M et al. | Anti-Helicobacter pylori and urease inhibition activities of some traditional medicinal plants. | 2013 | Molecules | pmid:23434867 |
Ogata SK et al. | High Helicobacter pylori resistance to metronidazole and clarithromycin in Brazilian children and adolescents. | 2013 | J. Pediatr. Gastroenterol. Nutr. | pmid:23403439 |
Morgan DR et al. | Risk of recurrent Helicobacter pylori infection 1 year after initial eradication therapy in 7 Latin American communities. | 2013 | JAMA | pmid:23403682 |
Bustamante-Rengifo JA et al. | In vitro effect of amoxicillin and clarithromycin on the 3' region of cagA gene in Helicobacter pylori isolates. | 2013 | World J. Gastroenterol. | pmid:24106405 |
Shallom SJ et al. | New rapid scheme for distinguishing the subspecies of the Mycobacterium abscessus group and identifying Mycobacterium massiliense isolates with inducible clarithromycin resistance. | 2013 | J. Clin. Microbiol. | pmid:23804391 |
Greupink R et al. | Semi-mechanistic physiologically-based pharmacokinetic modeling of clinical glibenclamide pharmacokinetics and drug-drug-interactions. | 2013 | Eur J Pharm Sci | pmid:23806476 |
Kim SG et al. | [Guidelines for the diagnosis and treatment of Helicobacter pylori infection in Korea, 2013 revised edition]. | 2013 | Korean J Gastroenterol | pmid:23954956 |
Park CW et al. | Advanced spray-dried design, physicochemical characterization, and aerosol dispersion performance of vancomycin and clarithromycin multifunctional controlled release particles for targeted respiratory delivery as dry powder inhalation aerosols. | 2013 | Int J Pharm | pmid:23820131 |
Yoshida S et al. | Further isolation of Mycobacterium abscessus subsp. abscessus and subsp. bolletii in different regions of Japan and susceptibility of these isolates to antimicrobial agents. | 2013 | Int. J. Antimicrob. Agents | pmid:23850022 |
Yu Q et al. | Treatment of pulmonary mucosa-associated lymphoid tissue lymphoma with clarithromycin. | 2013 | Chin. Med. J. | pmid:23786961 |
Dabirmoghaddam P et al. | The efficacy of clarithromycin in patients with severe nasal polyposis. | 2013 | Acta Med Iran | pmid:23852839 |
Chen PR and Tan SY | [The treatment outcomes of 21 cases of rapidly growing mycobacteria related pulmonary disease]. | 2013 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:23856140 |
Seyedmajidi S et al. | Penbactam for Helicobacter pylori eradication: a randomised comparison of quadruple and triple treatment schedules in an Iranian population. | 2013 | Arab J Gastroenterol | pmid:23622801 |
Kate V et al. | Sequential therapy versus standard triple-drug therapy for Helicobacter pylori eradication: a systematic review of recent evidence. | 2013 | Drugs | pmid:23625272 |
Kato H et al. | Addition of clarithromycin to lenalidomide/low-dose dexamethasone was effective in a case of relapsed myeloma after long-term use of lenalidomide. | 2013 | Ann. Hematol. | pmid:23625297 |
Bolhuis MS et al. | Clinical validation of the analysis of linezolid and clarithromycin in oral fluid of patients with multidrug-resistant tuberculosis. | 2013 | Antimicrob. Agents Chemother. | pmid:23689722 |
Seddik H et al. | Sequential therapy versus standard triple-drug therapy for Helicobacter pylori eradication: a prospective randomized study. | 2013 | Eur. J. Clin. Pharmacol. | pmid:23695545 |
Kwak HM et al. | The efficacy of cefazolin plus macrolide (erythromycin or clarithromycin) versus cefazolin alone in neonatal morbidity and placental inflammation for women with preterm premature rupture of membranes. | 2013 | Placenta | pmid:23465535 |
Liang JH et al. | Synthesis, antibacterial activity and docking of 14-membered 9-O-(3-arylalkyl) oxime 11,12-cyclic carbonate ketolides. | 2013 | Eur J Med Chem | pmid:23202851 |
Delavenne X et al. | A semi-mechanistic absorption model to evaluate drug-drug interaction with dabigatran: application with clarithromycin. | 2013 | Br J Clin Pharmacol | pmid:23210726 |
Duman DG et al. | Saccharomyces boulardii ameliorates clarithromycin- and methotrexate-induced intestinal and hepatic injury in rats. | 2013 | Br. J. Nutr. | pmid:23279717 |
Bessa LJ et al. | Helicobacter pylori free-living and biofilm modes of growth: behavior in response to different culture media. | 2013 | APMIS | pmid:23237527 |
Qvist T et al. | First report of lung transplantation in a patient with active pulmonary Mycobacterium simiae infection. | 2013 | Transplant. Proc. | pmid:23267789 |
Fiorini G et al. | Culture-based selection therapy for patients who did not respond to previous treatment for Helicobacter pylori infection. | 2013 | Clin. Gastroenterol. Hepatol. | pmid:23267869 |
Kute VB et al. | Bronchiolitis obliterans organizing pneumonia (BOOP) after renal transplantation. | 2013 | Int Urol Nephrol | pmid:22547135 |
Vu DH et al. | Troubleshooting carry-over of LC-MS/MS method for rifampicin, clarithromycin and metabolites in human plasma. | 2013 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:23353809 |
Kim SG et al. | Helicobacter pylori eradication on iatrogenic ulcer by endoscopic resection of gastric tumour: a prospective, randomized, placebo-controlled multi-centre trial. | 2013 | Dig Liver Dis | pmid:23333104 |
Lim JH et al. | Clinical outcomes of two-week sequential and concomitant therapies for Helicobacter pylori eradication: a randomized pilot study. | 2013 | Helicobacter | pmid:23305083 |
Dumpis U et al. | Assessment of antibiotic prescribing in Latvian general practitioners. | 2013 | BMC Fam Pract | pmid:23311389 |
Huang CW et al. | Synergistic activities of tigecycline with clarithromycin or amikacin against rapidly growing mycobacteria in Taiwan. | 2013 | Int. J. Antimicrob. Agents | pmid:23312605 |
Kawai Y et al. | Therapeutic efficacy of macrolides, minocycline, and tosufloxacin against macrolide-resistant Mycoplasma pneumoniae pneumonia in pediatric patients. | 2013 | Antimicrob. Agents Chemother. | pmid:23459497 |
Thomas M et al. | Periprosthetic atypical mycobacterial infection in breast implants: a new kid on the block! | 2013 | J Plast Reconstr Aesthet Surg | pmid:23122691 |
Pandey SK et al. | Antimalarial interaction of quinine and quinidine with clarithromycin. | 2013 | Parasitology | pmid:23137860 |
Lahbabi M et al. | Sequential therapy versus standard triple-drug therapy for Helicobacter pylori eradication: result of the HPFEZ randomised study. | 2013 | Clin Res Hepatol Gastroenterol | pmid:23168228 |
Darwish KM et al. | RP-HPLC/pre-column derivatization for analysis of omeprazole, tinidazole, doxycycline and clarithromycin. | 2013 | J Chromatogr Sci | pmid:23081968 |
Chodkiewicz HM and Cohen PR | Erythrasma: successful treatment after single-dose clarithromycin. | 2013 | Int. J. Dermatol. | pmid:23046434 |
Lin KJ et al. | Safety of macrolides during pregnancy. | 2013 | Am. J. Obstet. Gynecol. | pmid:23254249 |
Jouneau S et al. | Clarithromycin stops lung function decline in airway-centered interstitial fibrosis. | 2013 | Respiration | pmid:23095475 |
Secka O et al. | Antimicrobial susceptibility and resistance patterns among Helicobacter pylori strains from The Gambia, West Africa. | 2013 | Antimicrob. Agents Chemother. | pmid:23263004 |
Simoens S et al. | Preventing COPD exacerbations with macrolides: a review and budget impact analysis. | 2013 | Respir Med | pmid:23352223 |
Mueck W et al. | Co-administration of rivaroxaban with drugs that share its elimination pathways: pharmacokinetic effects in healthy subjects. | 2013 | Br J Clin Pharmacol | pmid:23305158 |
Seneviratne K and Herieka E | A rifampicin-resistant Mycobacterium marinum infection in a newly diagnosed HIV-1 individual. | 2013 | Int J STD AIDS | pmid:23512514 |
Ogawa K | Genetic research about Mycobacterium avium complex. | 2013 | Kekkaku | pmid:23513564 |
Liang JH et al. | Synthesis and antibacterial activity of 9-oxime ether non-ketolides, and novel binding mode of alkylides with bacterial rRNA. | 2013 | Bioorg. Med. Chem. Lett. | pmid:23375796 |
Karmakar S et al. | Hypokalemia: a potent risk for QTc prolongation in clarithromycin treated rats. | 2013 | Eur. J. Pharmacol. | pmid:23567068 |
Benajah DA et al. | Prevalence of Helicobacter pylori and its recurrence after successful eradication in a developing nation (Morocco). | 2013 | Clin Res Hepatol Gastroenterol | pmid:23567104 |
Bolhuis MS et al. | Clarithromycin increases linezolid exposure in multidrug-resistant tuberculosis patients. | 2013 | Eur. Respir. J. | pmid:23520311 |
Schembri S et al. | Cardiovascular events after clarithromycin use in lower respiratory tract infections: analysis of two prospective cohort studies. | 2013 | BMJ | pmid:23525864 |
Matsumoto T et al. | Education and imaging. Gastrointestinal: colonic mucosa-associated lymphoid tissue lymphoma regressed by levofloxacin. | 2013 | J. Gastroenterol. Hepatol. | pmid:23527757 |
Joosten M et al. | Case report: Helicobacter suis infection in a pig veterinarian. | 2013 | Helicobacter | pmid:23551953 |
Gisbert JP et al. | Second-line rescue triple therapy with levofloxacin after failure of non-bismuth quadruple "sequential" or "concomitant" treatment to eradicate H. pylori infection. | 2013 | Scand. J. Gastroenterol. | pmid:23556551 |
Pilcer G et al. | New co-spray-dried tobramycin nanoparticles-clarithromycin inhaled powder systems for lung infection therapy in cystic fibrosis patients. | 2013 | J Pharm Sci | pmid:23568616 |
Feng Z et al. | Dissociative disorder induced by clarithromycin combined with rabeprazole in a patient with gastritis. | 2013 | J. Int. Med. Res. | pmid:23569151 |
Gokmen T et al. | Clarithromycin treatment in preterm infants: a pilot study for prevention of feeding intolerance. | 2013 | J. Matern. Fetal. Neonatal. Med. | pmid:23570248 |
Metzler K et al. | Minimal inhibitory and mutant prevention concentrations of azithromycin, clarithromycin and erythromycin for clinical isolates of Streptococcus pneumoniae. | 2013 | J. Antimicrob. Chemother. | pmid:23169894 |
Semino-Mora C et al. | Antibiotic treatment decreases microbial burden associated with pseudomyxoma peritonei and affects β-catenin distribution. | 2013 | Clin. Cancer Res. | pmid:23743566 |
Cai M et al. | Macrolides inhibit cytokine production by alveolar macrophages in bronchiolitis obliterans organizing pneumonia. | 2013 | Immunobiology | pmid:23199585 |
Howard ST | Recent progress towards understanding genetic variation in the Mycobacterium abscessus complex. | 2013 | Tuberculosis (Edinb) | pmid:24388643 |
Ergül B et al. | The efficacy of two-week quadruple first-line therapy with bismuth, lansoprazole, amoxicillin, clarithromycin on Helicobacter pylori eradication: a prospective study. | 2013 | Helicobacter | pmid:24011287 |
Gandhi S et al. | Calcium-channel blocker-clarithromycin drug interactions and acute kidney injury. | 2013 | JAMA | pmid:24346990 |
Yu RX et al. | Köebner phenomenon induced by cupping therapy in a psoriasis patient. | 2013 | Dermatol. Online J. | pmid:24011324 |
Abenavoli L et al. | Association between non-alcoholic fatty liver disease, insulin resistance and Helicobacter pylori. | 2013 | Med. Hypotheses | pmid:24011768 |
Nagaoka K et al. | Macrolides inhibit Fusobacterium nucleatum-induced MUC5AC production in human airway epithelial cells. | 2013 | Antimicrob. Agents Chemother. | pmid:23380724 |
Makobongo MO et al. | In vitro characterization of the anti-bacterial activity of SQ109 against Helicobacter pylori. | 2013 | PLoS ONE | pmid:23935905 |
Unai S et al. | Sternal wound infection caused by Mycobacterium chelonae. | 2013 | J Card Surg | pmid:23941599 |