clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with clarithromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (5)
- Drug Metab. Dispos. (1)
- FEMS Immunol. Med. Microbiol. (1)
- Others (5)
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Morikawa K et al. | Modulatory effect of antibiotics on cytokine production by human monocytes in vitro. | 1996 | Antimicrob. Agents Chemother. | pmid:8726002 |
| Arain TM et al. | Bioluminescence screening in vitro (Bio-Siv) assays for high-volume antimycobacterial drug discovery. | 1996 | Antimicrob. Agents Chemother. | pmid:8726034 |
| Shafran SD et al. | A comparison of two regimens for the treatment of Mycobacterium avium complex bacteremia in AIDS: rifabutin, ethambutol, and clarithromycin versus rifampin, ethambutol, clofazimine, and ciprofloxacin. Canadian HIV Trials Network Protocol 010 Study Group. | 1996 | N. Engl. J. Med. | pmid:8676931 |
| Shimoyama T et al. | Validity of various diagnostic tests to evaluate cure of Helicobacter pylori infection. | 1996 | J. Gastroenterol. | pmid:8680535 |
| MacConnachie AM | Clarithromycin (klaricid, Abbott). | 1996 | Intensive Crit Care Nurs | pmid:8696027 |
| Meier A et al. | Molecular mechanisms of clarithromycin resistance in Mycobacterium avium: observation of multiple 23S rDNA mutations in a clonal population. | 1996 | J. Infect. Dis. | pmid:8699066 |
| Sellal A et al. | [Maintenance treatment of cerebral toxoplasmosis in AIDS: role of clarithromycin-minocycline combination]. | 1996 | Presse Med | pmid:8685115 |
| Schouenborg P | [Clarithromycin]. | 1996 | Ugeskr. Laeg. | pmid:8686028 |
| Goddard AF et al. | Effect of omeprazole on the distribution of metronidazole, amoxicillin, and clarithromycin in human gastric juice. | 1996 | Gastroenterology | pmid:8690200 |
| High-dose clarithromycin should be avoided. | 1996 | AIDS Alert | pmid:11363723 | |
| Lambert JR | Pharmacology of the gastric mucosa: a rational approach to Helicobacter polytherapy. | 1996 | Gastroenterology | pmid:8690219 |
| Pot shots. | 1996 | Notes Undergr | pmid:11363915 | |
| Bates JH | Mycobacterium avium disease: progress at last. | 1996 | Am. J. Respir. Crit. Care Med. | pmid:8665029 |
| Bowersox J | CPCRA researchers present OI studies at Vancouver. | 1996 | NIAID AIDS Agenda | pmid:11363924 |
| Wallace RJ et al. | Clarithromycin regimens for pulmonary Mycobacterium avium complex. The first 50 patients. | 1996 | Am. J. Respir. Crit. Care Med. | pmid:8665032 |
| MAC management. | 1996 | PI Perspect | pmid:11363967 | |
| Frothingham R | Clarithromycin treatment for Mycobacterium avium-intracellulare complex lung disease. | 1996 | Am. J. Respir. Crit. Care Med. | pmid:8665069 |
| O'Hara K and Yamamoto K | Reaction of roxithromycin and clarithromycin with macrolide-inactivating enzymes from highly erythromycin-resistant Escherichia coli. | 1996 | Antimicrob. Agents Chemother. | pmid:8849224 |
| Flurer CL | Analysis of macrolide antibiotics by capillary electrophoresis. | 1996 | Electrophoresis | pmid:8900943 |
| Segreti J et al. | In vitro activity of macrolides against intracellular Legionella pneumophila. | 1996 | Diagn. Microbiol. Infect. Dis. | pmid:8902407 |
| Pellegrin I et al. | Activity of rifabutin, clarithromycin, ethambutol, sparfloxacin and amikacin, alone and in combination, against Mycobacterium avium complex in human macrophages. | 1996 | J. Antimicrob. Chemother. | pmid:9182107 |
| Vermot D et al. | Efficacy of clarithromycin versus that of clindamycin for single-dose prophylaxis of experimental streptococcal endocarditis. | 1996 | Antimicrob. Agents Chemother. | pmid:8851620 |
| Apseloff G et al. | Severe neutropenia caused by recommended prophylactic doses of rifabutin. | 1996 | Lancet | pmid:8782773 |
| Gisbert JP et al. | Response to article by Forné et al. | 1996 | Am. J. Gastroenterol. | pmid:8561132 |
| Steinman MA and Steinman TI | Clarithromycin-associated visual hallucinations in a patient with chronic renal failure on continuous ambulatory peritoneal dialysis. | 1996 | Am. J. Kidney Dis. | pmid:8546130 |
| Pankuch GA et al. | MIC and time-kill study of antipneumococcal activities of RPR 106972 (a new oral streptogramin), RP 59500 (quinupristin-dalfopristin), pyostacine (RP 7293), penicillin G, cefotaxime, erythromycin, and clarithromycin against 10 penicillin-susceptible and -resistant pneumococci. | 1996 | Antimicrob. Agents Chemother. | pmid:8878583 |
| Ednie LM et al. | Comparative activities of clarithromycin, erythromycin, and azithromycin against penicillin-susceptible and penicillin-resistant pneumococci. | 1996 | Antimicrob. Agents Chemother. | pmid:8843313 |
| Conte JE et al. | Single-dose intrapulmonary pharmacokinetics of azithromycin, clarithromycin, ciprofloxacin, and cefuroxime in volunteer subjects. | 1996 | Antimicrob. Agents Chemother. | pmid:8807050 |
| Nash KA and Inderlied CB | Rapid detection of mutations associated with macrolide resistance in Mycobacterium avium complex. | 1996 | Antimicrob. Agents Chemother. | pmid:8807078 |
| Xu G et al. | Effect of macrolide antibiotics on macrophage functions. | 1996 | Microbiol. Immunol. | pmid:8865152 |
| Matsuoka N et al. | Inhibitory effect of clarithromycin on costimulatory molecule expression and cytokine production by synovial fibroblast-like cells. | 1996 | Clin. Exp. Immunol. | pmid:9099936 |
| Tateda K et al. | Direct evidence for antipseudomonal activity of macrolides: exposure-dependent bactericidal activity and inhibition of protein synthesis by erythromycin, clarithromycin, and azithromycin. | 1996 | Antimicrob. Agents Chemother. | pmid:8891128 |
| van der Hulst RW et al. | Therapeutic options after failed Helicobacter pylori eradication therapy. | 1996 | Am. J. Gastroenterol. | pmid:8931413 |
| Alder JD et al. | Relevance of the ferret model of Helicobacter-induced gastritis to evaluation of antibacterial therapies. | 1996 | Am. J. Gastroenterol. | pmid:8931416 |
| Vilmà nyi E et al. | Clarithromycin pharmacokinetics after oral administration with or without fasting in crossbred beagles. | 1996 | J Small Anim Pract | pmid:8934426 |
| Flisch CW et al. | [A case of arthritis of the wrist caused by Mycobacterium marinum. Review of the literature]. | 1996 | Ann Chir Main Memb Super | pmid:9026056 |
| Alarcón T et al. | In vitro activity of omeprazole in combination with several antimicrobial agents against clinical isolates of Helicobacter pylori. | 1996 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:9031877 |
| Burucoa C et al. | Western blot monitoring of disseminated Nocardia nova infection treated with clarithromycin, imipenem, and surgical drainage. | 1996 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:9031879 |
| Koeck JL et al. | Disseminated Mycobacterium simiae infection in a patient with AIDS: clinical features and treatment. | 1996 | Clin. Infect. Dis. | pmid:8909856 |
| Liviu L et al. | Pancreatitis induced by clarithromycin. | 1996 | Ann. Intern. Med. | pmid:8849171 |
| Drouet M et al. | [Unusual clinical form of amoxicillin allergy]. | 1996 | Allerg Immunol (Paris) | pmid:9011169 |
| Ramirez Mayans JA et al. | [Elimination of Helicobacter pylori in patients with recurrent abdominal pain with simultaneous administration of ranitidine, bismuth subsalicylate and clarithromycin]. | 1996 | Acta Gastroenterol. Latinoam. | pmid:9363265 |
| Thompson D and Oster G | Use of terfenadine and contraindicated drugs. | 1996 | JAMA | pmid:8614120 |
| Stone GG et al. | Identification of a 23S rRNA gene mutation in clarithromycin-resistant Helicobacter pylori. | 1996 | Helicobacter | pmid:9432314 |
| Pozniak A and Nelson MR | Against the proposition: all patients with advanced HIV disease should be offered rifabutin prophylaxis. | 1996 | Genitourin Med | pmid:8976832 |
| Dammann HG | Therapy with omeprazole and clarithromycin increases serum carbamazepine levels in patients with H. pylori gastritis. | 1996 | Dig. Dis. Sci. | pmid:8617126 |
| Meyboom RH et al. | [Possible potentiation of phenprocoumon by clarithromycin and roxithromycin]. | 1996 | Ned Tijdschr Geneeskd | pmid:8628425 |
| Hunt RH | Eradication of Helicobacter pylori infection. | 1996 | Am. J. Med. | pmid:8644782 |
| Torriani FJ et al. | Disseminated Mycobacterium avium complex: correlation between blood and tissue burden. | 1996 | J. Infect. Dis. | pmid:8603975 |
| Diemer PR et al. | [Rifabutin-induced hypopyon iritis in HIV infection]. | 1996 | Klin Monbl Augenheilkd | pmid:8965476 |
| Vakil N and Fennerty MB | Cost-effectiveness of treatment regimens for the eradication of Helicobacter pylori in duodenal ulcer. | 1996 | Am. J. Gastroenterol. | pmid:8607487 |
| Labenz J | [Current developments in Helicobacter pylori therapy]. | 1996 | Leber Magen Darm | pmid:8965606 |
| Treiber G | The influence of drug dosage on Helicobacter pylori eradication: a cost-effectiveness analysis. | 1996 | Am. J. Gastroenterol. | pmid:8607488 |
| Grau E et al. | Interaction between clarithromycin and oral anticoagulants. | 1996 | Ann Pharmacother | pmid:8968465 |
| Shaheen N and Grimm IS | Fulminant hepatic failure associated with clarithromycin. | 1996 | Am. J. Gastroenterol. | pmid:8607519 |
| Horowitz RS et al. | Clinical ergotism with lingual ischemia induced by clarithromycin-ergotamine interaction. | 1996 | Arch. Intern. Med. | pmid:8607732 |
| Muñoz N et al. | Chemoprevention trial on precancerous lesions of the stomach in Venezuela: summary of study design and baseline data. | 1996 | IARC Sci. Publ. | pmid:8923024 |
| Labenz J et al. | [Ulcer healing through the elimination of Helicobacter pylori: is a week of therapy enough?]. | 1996 | Dtsch. Med. Wochenschr. | pmid:8565802 |
| Dhaenens L et al. | In-vitro activities of clarithromycin and other antimicrobial agents against Helicobacter pylori isolated from children. | 1996 | J. Antimicrob. Chemother. | pmid:8877551 |
| Tursi A et al. | Helicobacter pylori eradication helps resolve pyloric and duodenal stenosis. | 1996 | J. Clin. Gastroenterol. | pmid:8877648 |
| Goh KL et al. | Helicobacter pylori eradication with short-term therapy leads to duodenal ulcer healing without the need for continued acid suppression therapy. | 1996 | Eur J Gastroenterol Hepatol | pmid:8804868 |
| Thor P et al. | Dysfunction in gastric myoelectric and motor activity in Helicobacter pylori positive gastritis patients with non-ulcer dyspesia. | 1996 | J. Physiol. Pharmacol. | pmid:8877902 |
| Ji B et al. | Bactericidal activity of single dose of clarithromycin plus minocycline, with or without ofloxacin, against Mycobacterium leprae in patients. | 1996 | Antimicrob. Agents Chemother. | pmid:8878595 |
| Heifets L | Susceptibility testing of Mycobacterium avium complex isolates. | 1996 | Antimicrob. Agents Chemother. | pmid:8843278 |
| Alper CM et al. | Efficacy of clarithromycin treatment of acute otitis media caused by infection with penicillin-susceptible, -intermediate, and -resistant Streptococcus pneumoniae in the chinchilla. | 1996 | Antimicrob. Agents Chemother. | pmid:8843299 |
| Chen S et al. | [Omeprazole, clarithromycin and amoxicillin therapy for Helicobacter pylori infection]. | 1996 | Zhonghua Nei Ke Za Zhi | pmid:9592303 |
| Rana KZ et al. | Clarithromycin does not affect phosphorylation of zidovudine in vitro. | 1996 | Antimicrob. Agents Chemother. | pmid:8843311 |
| Liu W et al. | [Clarithromycin combined short-term triple therapies for eradication of Helicobacter pylori infection]. | 1996 | Zhonghua Nei Ke Za Zhi | pmid:9592304 |
| Flamm RK et al. | Kill kinetics of antimicrobial agents against Helicobacter pylori. | 1996 | J. Antimicrob. Chemother. | pmid:8937967 |
| Bermudez LE et al. | Effect of ethambutol on emergence of clarithromycin-resistant Mycobacterium avium complex in the beige mouse model. | 1996 | J. Infect. Dis. | pmid:8940212 |
| Nagashima R et al. | Regression of duodenal mucosa-associated lymphoid tissue lymphoma after eradication of Helicobacter pylori. | 1996 | Gastroenterology | pmid:8942749 |
| Pijpers E et al. | A clarithromycin-induced myasthenic syndrome. | 1996 | Clin. Infect. Dis. | pmid:8824993 |
| Webb DD | Practice guidelines for treatment of peptic ulcer disease. | 1996 | JAMA | pmid:8827959 |
| Erah PO et al. | Ion-pair high-performance liquid chromatographic assay method for the assessment of clarithromycin stability in aqueous solution and in gastric juice. | 1996 | J. Chromatogr. B, Biomed. Appl. | pmid:8832427 |
| Vangala R and Cernek PK | Hypersensitivity reaction to clarithromycin. | 1996 | Ann Pharmacother | pmid:8833572 |
| Ji B et al. | Bactericidal activities of combinations of new drugs against Mycobacterium leprae in nude mice. | 1996 | Antimicrob. Agents Chemother. | pmid:8834886 |
| Yamamoto T et al. | Activity of KRM-1648 alone or in combination with both ethambutol and kanamycin or clarithromycin against Mycobacterium intracellulare infections in beige mice. | 1996 | Antimicrob. Agents Chemother. | pmid:8834892 |
| Ji B et al. | How effective is KRM-1648 in treatment of disseminated Mycobacterium avium complex infections in beige mice? | 1996 | Antimicrob. Agents Chemother. | pmid:8834894 |
| Dattwyler RJ et al. | Clarithromycin in treatment of early Lyme disease: a pilot study. | 1996 | Antimicrob. Agents Chemother. | pmid:8834900 |
| Yousfi MM et al. | Resolution of a metaplastic duodenal polyp after cure of Helicobacter pylori infection. | 1996 | J. Clin. Gastroenterol. | pmid:8835902 |
| Versalovic J et al. | Mutations in 23S rRNA are associated with clarithromycin resistance in Helicobacter pylori. | 1996 | Antimicrob. Agents Chemother. | pmid:8834903 |
| Wallace RJ et al. | Genetic basis for clarithromycin resistance among isolates of Mycobacterium chelonae and Mycobacterium abscessus. | 1996 | Antimicrob. Agents Chemother. | pmid:8807061 |
| Gillum JG et al. | Effect of combination therapy with ciprofloxacin and clarithromycin on theophylline pharmacokinetics in healthy volunteers. | 1996 | Antimicrob. Agents Chemother. | pmid:8807068 |
| McLinn S and Williams D | Incidence of antibiotic-resistant Streptococcus pneumoniae and beta-lactamase-positive Haemophilus influenzae in clinical isolates from patients with otitis media. | 1996 | Pediatr. Infect. Dis. J. | pmid:8878239 |
| Gross U and Pohl F | Influence of antimicrobial agents on replication and stage conversion of Toxoplasma gondii. | 1996 | Curr. Top. Microbiol. Immunol. | pmid:8791704 |
| Peterson WL et al. | Ranitidine bismuth citrate plus clarithromycin is effective for healing duodenal ulcers, eradicating H. pylori and reducing ulcer recurrence. RBC H. pylori Study Group. | 1996 | Aliment. Pharmacol. Ther. | pmid:8791947 |
| Delchier JC et al. | Omeprazole-amoxycillin versus omeprazole-amoxycillin-clarithromycin in the eradication of Helicobacter pylori. | 1996 | Aliment. Pharmacol. Ther. | pmid:8791948 |
| Riff DS et al. | Triple therapy with lansoprazole, clarithromycin, and amoxicillin for the cure of Helicobacter pylori infection: a short report. | 1996 | Helicobacter | pmid:9398874 |
| Harford W et al. | Double-blind, multicenter evaluation of lansoprazole and amoxicillin dual therapy for the cure of Helicobacter pylori infection. | 1996 | Helicobacter | pmid:9398875 |
| Schwartz H et al. | Seven-day triple therapy with lansoprazole, clarithromycin, and metronidazole for the cure of Helicobacter pylori infection: a short report. | 1996 | Helicobacter | pmid:9398876 |
| Wenisch C et al. | Effect of single oral dose of azithromycin, clarithromycin, and roxithromycin on polymorphonuclear leukocyte function assessed ex vivo by flow cytometry. | 1996 | Antimicrob. Agents Chemother. | pmid:8878577 |
| Jaup BK | Duodenal ulcer healing after 7-day treatment: a pilot study with lansoprazole, amoxicillin, and clarithromycin. | 1996 | Helicobacter | pmid:9398878 |
| Moayyedi P et al. | Comparison of one or two weeks of lansoprazole, amoxicillin, and clarithromycin in the treatment of Helicobacter pylori. | 1996 | Helicobacter | pmid:9398880 |
| Mégraud F and Malfertheiner P | Treatment of Helicobacter pylori infection: summary of a meeting at the Fourth United European Gastroenterology Week, September 20, 1995. | 1996 | Helicobacter | pmid:9398889 |
| O'Morain C et al. | Double-blind, multicenter, placebo-controlled evaluation of clarithromycin and omeprazole for Helicobacter pylori-associated duodenal ulcer. | 1996 | Helicobacter | pmid:9398893 |
| Lind T et al. | Eradication of Helicobacter pylori using one-week triple therapies combining omeprazole with two antimicrobials: the MACH I Study. | 1996 | Helicobacter | pmid:9398894 |
| Mehaffey PC et al. | Evaluation of in vitro spectra of activity of azithromycin, clarithromycin, and erythromycin tested against strains of Neisseria gonorrhoeae by reference agar dilution, disk diffusion, and Etest methods. | 1996 | J. Clin. Microbiol. | pmid:8789046 |
| Goddard AF and Logan RP | Antimicrobial resistance and Helicobacter pylori. | 1996 | J. Antimicrob. Chemother. | pmid:8722530 |
| Barry AL et al. | Reassessment of methods for testing the susceptibility of Haemophilus influenzae to clarithromycin. | 1996 | J. Antimicrob. Chemother. | pmid:8722555 |
| H. pylori treatment recognized by FDA. | 1996 | Am J Health Syst Pharm | pmid:8725200 |