clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with clarithromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (2)
- J. Antimicrob. Chemother. (1)
- Clin. Diagn. Lab. Immunol. (1)
- Others (2)
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kruppa A et al. | Immediate reaction to roxithromycin and prick test cross-sensitization to erythromycin and clarithromycin. | 1998 | Dermatology (Basel) | pmid:9621142 |
| Ishii K et al. | Comparative study of pharmacokinetic parameters between clarithromycin and erythromycin stearate in relation to their physicochemical properties. | 1998 | Drug Dev Ind Pharm | pmid:15605442 |
| Wallace RJ and Brown BA | Catheter sepsis due to Mycobacterium chelonae. | 1998 | J. Clin. Microbiol. | pmid:9867491 |
| Shafran SD et al. | Does in vitro susceptibility to rifabutin and ethambutol predict the response to treatment of Mycobacterium avium complex bacteremia with rifabutin, ethambutol, and clarithromycin? Canadian HIV Trials Network Protocol 010 Study Group. | 1998 | Clin. Infect. Dis. | pmid:9868650 |
| van Westrhenen R et al. | Pneumonia and glomerulonephritis caused by Mycoplasma pneumoniae. | 1998 | Nephrol. Dial. Transplant. | pmid:9870493 |
| Waddell ST et al. | Synthesis and antibacterial activity of O-methyl derivatives of azalide antibiotics: II. 6-OME derivatives via clarithromycin. | 1998 | Bioorg. Med. Chem. Lett. | pmid:9871759 |
| Lee CL et al. | One-week low-dose triple therapy is effective in treating Helicobacter pylori-infected patients with bleeding peptic ulcers. | 1998 | J. Formos. Med. Assoc. | pmid:9872028 |
| Suzuki J et al. | Relationship between the eradication of Helicobacter pylori and the healing pattern of peptic ulcer. | 1998 | J. Clin. Gastroenterol. | pmid:9872515 |
| Kondoh K and Hashiba M | [Inhibitory effect of macrolide antibiotics on biofilm formation by Pseudomonas aeruginosa]. | 1998 | Nippon Jibiinkoka Gakkai Kaiho | pmid:9493436 |
| Pipkin GA et al. | Review article: one-week clarithromycin triple therapy regimens for eradication of Helicobacter pylori. | 1998 | Aliment. Pharmacol. Ther. | pmid:9768524 |
| Louw JA et al. | Helicobacter pylori eradication and ulcer healing with daily lansoprazole, plus 1 or 2 weeks co-therapy with amoxycillin and clarithromycin. | 1998 | Aliment. Pharmacol. Ther. | pmid:9768531 |
| Laine L et al. | Low rate of emergence of clarithromycin-resistant Helicobacter pylori with amoxycillin co-therapy. | 1998 | Aliment. Pharmacol. Ther. | pmid:9768532 |
| Debets-Ossenkopp YJ et al. | Explaining the bias in the 23S rRNA gene mutations associated with clarithromycin resistance in clinical isolates of Helicobacter pylori. | 1998 | Antimicrob. Agents Chemother. | pmid:9756790 |
| Mukunda BN et al. | Clarithromycin therapy for bacillary peliosis did not prevent bacillary angiomatosis. | 1998 | Clin. Infect. Dis. | pmid:9770180 |
| Stack WA et al. | Safety and efficacy of rabeprazole in combination with four antibiotic regimens for the eradication of Helicobacter pylori in patients with chronic gastritis with or without peptic ulceration. | 1998 | Am. J. Gastroenterol. | pmid:9772054 |
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| Stolte M et al. | Cure of autoimmune gastritis by Helicobacter pylori eradication in a 21-year-old male. | 1998 | Z Gastroenterol | pmid:9773482 |
| Pina M et al. | Detection of point mutations associated with resistance of Helicobacter pylori to clarithromycin by hybridization in liquid phase. | 1998 | J. Clin. Microbiol. | pmid:9774580 |
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| Hermon-Taylor J et al. | Mycobacterium paratuberculosis cervical lymphadenitis, followed five years later by terminal ileitis similar to Crohn's disease. | 1998 | BMJ | pmid:9492675 |
| Abe M et al. | A case of diffuse panbronchiolitis effectively treated with low-dose macrolide antibiotics and leukotriene D4/E4 receptor antagonist. | 1998 | Respir Med | pmid:9893782 |
| Warheker PT et al. | Successful treatment of saccular endophthalmitis with clarithromycin. | 1998 | Eye (Lond) | pmid:10326009 |
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| Griffith DE | Mycobacteria as pathogens of respiratory infection. | 1998 | Infect. Dis. Clin. North Am. | pmid:9779380 |
| Casswall TH et al. | One-week treatment with omeprazole, clarithromycin, and metronidazole in children with Helicobacter pylori infection. | 1998 | J. Pediatr. Gastroenterol. Nutr. | pmid:9779970 |
| Aberg JA et al. | Eradication of AIDS-related disseminated mycobacterium avium complex infection after 12 months of antimycobacterial therapy combined with highly active antiretroviral therapy. | 1998 | J. Infect. Dis. | pmid:9780266 |
| González Carro P et al. | [Efficacy of an ultrashort protocol in the eradication of Helicobacter pylori]. | 1998 | Rev Esp Enferm Dig | pmid:9780793 |
| Gangadharam PR | Clarithromycin for non-mycobacterial diseases? | 1998 | Int. J. Tuberc. Lung Dis. | pmid:9783536 |
| Hahn DL et al. | Evidence for Chlamydia pneumoniae infection in steroid-dependent asthma. | 1998 | Ann. Allergy Asthma Immunol. | pmid:9475566 |
| Treiber G et al. | Amoxicillin/metronidazole/omeprazole/clarithromycin: a new, short quadruple therapy for Helicobacter pylori eradication. | 1998 | Helicobacter | pmid:9546119 |
| Preston SL et al. | Drug interactions in HIV-positive patients initiated on protease inhibitor therapy. | 1998 | AIDS | pmid:9468380 |
| Suzuki J et al. | Assessment of a new triple agent regimen for the eradication of Helicobacter pylori and the nature of H. pylori resistance to this therapy in Japan. | 1998 | Helicobacter | pmid:9546120 |
| Lindsetmo RO et al. | Lansoprazole, amoxicillin, and clarithromycin triple therapy in vagotomized patients with dyspeptic complaints. A randomized, double-blind, placebo-controlled, clinical study without pretreatment diagnostic upper endoscopy. | 1998 | Scand. J. Gastroenterol. | pmid:9548613 |
| Comet R et al. | [Seven-day omeprazole, clarithromycin, and amoxicillin for the therapy of Helicobacter pylori infection]. | 1998 | Gastroenterol Hepatol | pmid:9549183 |
| Carnicer J | [Helicobacter pylori infection and recurrent abdominal pain in children. A proved relationship?]. | 1998 | Gastroenterol Hepatol | pmid:9549199 |
| Iwata M et al. | [Three cases of Fitz-Hugh-Curtis syndrome detected in the early stage by abdominal ultrasonography]. | 1998 | Nippon Naika Gakkai Zasshi | pmid:9549331 |
| Rosina P et al. | Fixed drug eruption from clarithromycin. | 1998 | Contact Derm. | pmid:9506224 |
| Murata H et al. | Evaluation of the PyloriTek test for detection of Helicobacter pylori infection in cases with and without eradication therapy. | 1998 | Am. J. Gastroenterol. | pmid:9820380 |
| Laine L et al. | Twice-daily, 10-day triple therapy with omeprazole, amoxicillin, and clarithromycin for Helicobacter pylori eradication in duodenal ulcer disease: results of three multicenter, double-blind, United States trials. | 1998 | Am. J. Gastroenterol. | pmid:9820381 |
| Kaeser YA et al. | Severe hypotension and bradycardia associated with verapamil and clarithromycin. | 1998 | Am J Health Syst Pharm | pmid:9825040 |
| Hua J et al. | Characterization of clinical isolates of Helicobacter pylori in Singapore. | 1998 | Microbios | pmid:9785486 |
| Clark CL et al. | Antipneumococcal activities of levofloxacin and clarithromycin as determined by agar dilution, microdilution, E-test, and disk diffusion methodologies. | 1998 | J. Clin. Microbiol. | pmid:9817876 |
| Björkholm B et al. | Rapid PCR detection of Helicobacter pylori-associated virulence and resistance genes directly from gastric biopsy material. | 1998 | J. Clin. Microbiol. | pmid:9817898 |
| Miyamoto N et al. | [Test to set dosages for long-term administration of clarithromycin to treat chronic paranasal sinusitis]. | 1998 | Jpn J Antibiot | pmid:9597498 |
| Fujita K et al. | [Neutrophil count and IL-8 level of nasal secretion of patients with chronic paranasal sinusitis and the effects of macrolide antibiotics]. | 1998 | Jpn J Antibiot | pmid:9597505 |
| Goujard C et al. | Clarithromycin-resistant Mycobacterium avium strain in a clarithromycin-naive AIDS patient. | 1998 | Clin. Infect. Dis. | pmid:9455532 |
| Williamson R et al. | New options in Helicobacter pylori eradication: efficacy, resistance and synergy. | 1998 | Scand. J. Gastroenterol. Suppl. | pmid:9515751 |
| Bardhan KD et al. | Ranitidine bismuth citrate with clarithromycin given twice daily effectively eradicates Helicobacter pylori and heals duodenal ulcers. | 1998 | Am. J. Gastroenterol. | pmid:9517644 |
| Adamek RJ et al. | Primary and acquired Helicobacter pylori resistance to clarithromycin, metronidazole, and amoxicillin--influence on treatment outcome. | 1998 | Am. J. Gastroenterol. | pmid:9517645 |
| Hafner R et al. | Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers. | 1998 | Antimicrob. Agents Chemother. | pmid:9517944 |
| Fattorini L et al. | Activities of isoniazid alone and in combination with other drugs against Mycobacterium avium infection in beige mice. | 1998 | Antimicrob. Agents Chemother. | pmid:9517960 |
| Trivedi S et al. | Clarithromycin and digoxin toxicity. | 1998 | Ann. Intern. Med. | pmid:9518419 |
| Laine L and Fendrick AM | Helicobacter pylori and peptic ulcer disease. Bridging the gap between knowledge and treatment. | 1998 | Postgrad Med | pmid:9519040 |
| Sörberg M et al. | Risk of development of in vitro resistance to amoxicillin, clarithromycin, and metronidazole in Helicobacter pylori. | 1998 | Antimicrob. Agents Chemother. | pmid:9593154 |
| Roussel G and Igual J | Clarithromycin with minocycline and clofazimine for Mycobacterium avium intracellulare complex lung disease in patients without the acquired immune deficiency syndrome. GETIM. Groupe d'Etude et de Traitement des Infections à Mycobactéries. | 1998 | Int. J. Tuberc. Lung Dis. | pmid:9626603 |
| Archimandritis A et al. | Clostridium difficile colitis associated with a 'triple' regimen, containing clarithromycin and metronidazole, to eradicate Helicobacter pylori. | 1998 | J. Intern. Med. | pmid:9627163 |
| Petersen AM et al. | [Resistance of Helicobacter pylori to clarithomycin]. | 1998 | Ugeskr. Laeg. | pmid:9627511 |
| Domingo D et al. | High frequency of mutations at position 2144 of the 23S rRNA gene in clarithromycin-resistant Helicobacter pylori strains isolated in Spain. | 1998 | J. Antimicrob. Chemother. | pmid:9630414 |
| Fireman Z et al. | Helicobacter pylori and peptic ulcer disease therapies: a survey of gastroenterologists in Israel. | 1998 | Helicobacter | pmid:9631306 |
| Battaglia G et al. | Optimal PPI-based triple therapy for the cure of Helicobacter pylori infection: a single center comparison of four 14-day schedules. | 1998 | Helicobacter | pmid:9631310 |
| Miwa H et al. | Effectiveness of omeprazole-amoxicillin-clarithromycin (OAC) therapy for Helicobacter pylori infection in a Japanese population. | 1998 | Helicobacter | pmid:9631313 |
| Holmberg SD et al. | Possible effectiveness of clarithromycin and rifabutin for cryptosporidiosis chemoprophylaxis in HIV disease. HIV Outpatient Study (HOPS) Investigators. | 1998 | JAMA | pmid:9459473 |
| Gray VS | Syncopal episodes associated with cisapride and concurrent drugs. | 1998 | Ann Pharmacother | pmid:9640482 |
| Grove DI et al. | Comparison of culture, histopathology and urease testing for the diagnosis of Helicobacter pylori gastritis and susceptibility to amoxycillin, clarithromycin, metronidazole and tetracycline. | 1998 | Pathology | pmid:9643503 |
| Makhani S et al. | Atypical cervico-facial mycobacterial infections in childhood. | 1998 | Br J Oral Maxillofac Surg | pmid:9643597 |
| Dehesa M et al. | [Comparison of 2 schedules based on pantoprazole for eradication of Helicobacter pylori in patients with active duodenal ulcer]. | 1998 Apr-Jun | Rev Gastroenterol Mex | pmid:10068730 |
| Fennerty MB et al. | A comparison of 10 and 14 days of lansoprazole triple therapy for eradication of Helicobacter pylori. | 1998 Aug 10-24 | Arch. Intern. Med. | pmid:9701099 |
| Mikamo H et al. | Effects of long-term/low-dose clarithromycin on neutrophil count and interleukin-8 level in pyometra. | 1998 Jan-Feb | Chemotherapy | pmid:9444409 |
| Ziering W and McElvaine P | Randomized comparison of once-daily ceftibuten and twice-daily clarithromycin in the treatment of acute exacerbation of chronic bronchitis. | 1998 Jan-Feb | Infection | pmid:9505188 |
| Langan C et al. | Short-course cefuroxime axetil therapy in the treatment of acute exacerbations of chronic bronchitis. | 1998 Jul-Aug | Int. J. Clin. Pract. | pmid:9796558 |
| Habu Y et al. | Triple therapy with omeprazole, amoxicillin and clarithromycin is effective against Helicobacter pylori infection in gastric ulcer patients as well as in duodenal ulcer patients. Results of a randomized controlled trial in Japan. | 1998 Jul-Aug | Digestion | pmid:9693202 |
| Shafran SD | Prevention and treatment of disseminated Mycobacterium avium complex infection in human immunodeficiency virus-infected individuals. | 1998 Jul-Sep | Int. J. Infect. Dis. | pmid:9831675 |
| Venuta A et al. | Azithromycin compared with clarithromycin for the treatment of streptococcal pharyngitis in children. | 1998 Jun-Jul | J. Int. Med. Res. | pmid:9718470 |
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| Oberg KC | Delayed elevation of international normalized ratio with concurrent clarithromycin and warfarin therapy. | 1998 Mar-Apr | Pharmacotherapy | pmid:9545160 |
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| Miehlke S et al. | Comparison of omeprazole, metronidazole and clarithromycin with omeprazole/amoxicillin dual-therapy for the cure of Helicobacter pylori infection. | 1998 Nov-Dec | Digestion | pmid:9813387 |
| Adelglass J et al. | A multicenter, investigator-blinded, randomized comparison of oral levofloxacin and oral clarithromycin in the treatment of acute bacterial sinusitis. | 1998 Nov-Dec | Pharmacotherapy | pmid:9855324 |
| Tohnai A et al. | Clarithromycin suppresses proliferation of rat nasal epithelium exposed to endotoxin. | 1998 Nov-Dec | Am J Rhinol | pmid:9883303 |
| Mermelstein HT | Clarithromycin-induced delirium in a general hospital. | 1998 Nov-Dec | Psychosomatics | pmid:9819955 |
| Anzueto A et al. | Etiology, susceptibility, and treatment of acute bacterial exacerbations of complicated chronic bronchitis in the primary care setting: ciprofloxacin 750 mg b.i.d. versus clarithromycin 500 mg b.i.d. Bronchitis Study Group. | 1998 Sep-Oct | Clin Ther | pmid:9829441 |
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| Iakovlev VP | [New semisynthetic macrolides. Clarithromycin--its importance in the current therapy of bacterial infections]. | 1999 | Antibiot. Khimioter. | pmid:10635418 |
| Keiser P et al. | A retrospective study of the addition of ciprofloxacin to clarithromycin and ethambutol in the treatment of disseminated Mycobacterium avium complex infection. | 1999 | Int J STD AIDS | pmid:10639059 |
| Gschwantler M et al. | Famotidine versus omeprazole in combination with clarithromycin and metronidazole for eradication of Helicobacter pylori--a randomized, controlled trial. | 1999 | Aliment. Pharmacol. Ther. | pmid:10468682 |
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| Sonnenberg A et al. | Antibiotic therapy of Helicobacter pylori infection reduces healthcare expenditures related to duodenal ulcer. | 1999 | Am J Manag Care | pmid:10345967 |
| Clifford K et al. | Double-blind comparative trial of ciprofloxacin versus clarithromycin in the treatment of acute bacterial sinusitis. Sinusitis Infection Study Group. | 1999 | Ann. Otol. Rhinol. Laryngol. | pmid:10214783 |
| Debets-Ossenkopp YJ et al. | Prevalence of Helicobacter pylori resistance to metronidazole, clarithromycin, amoxycillin, tetracycline and trovafloxacin in The Netherlands. | 1999 | J. Antimicrob. Chemother. | pmid:10350380 |
| Burgess DS et al. | A time-kill evaluation of clarithromycin and azithromycin against two extracellular pathogens and the development of resistance. | 1999 | Ann Pharmacother | pmid:10630825 |
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