clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with clarithromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (5)
- Drug Metab. Dispos. (1)
- FEMS Immunol. Med. Microbiol. (1)
- Others (5)
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Spisso BF et al. | Simultaneous determination of polyether ionophores, macrolides and lincosamides in hen eggs by liquid chromatography-electrospray ionization tandem mass spectrometry using a simple solvent extraction. | 2010 | Anal. Chim. Acta | pmid:21056719 |
| Xing J et al. | The application of high-resolution mass spectrometry-based data-mining tools in tandem to metabolite profiling of a triple drug combination in humans. | 2015 | Anal. Chim. Acta | pmid:26515003 |
| Eremenko AA et al. | [Effect of clarithromycin on the systemic inflammatory response syndrome severity in patients after myocardial revascularization surgery]. | 2012 May-Jun | Anesteziol Reanimatol | pmid:22993930 |
| Aguilar JA et al. | Decoupling two-dimensional NMR spectroscopy in both dimensions: pure shift NOESY and COSY. | 2012 | Angew. Chem. Int. Ed. Engl. | pmid:22588724 |
| Stricker RB et al. | Longterm decrease in the CD57 lymphocyte subset in a patient with chronic Lyme disease. | 2002 | Ann Agric Environ Med | pmid:12088407 |
| Miwa S et al. | Efficacy of clarithromycin and ethambutol for Mycobacterium avium complex pulmonary disease. A preliminary study. | 2014 | Ann Am Thorac Soc | pmid:24298907 |
| Morimoto K et al. | A Laboratory-based Analysis of Nontuberculous Mycobacterial Lung Disease in Japan from 2012 to 2013. | 2017 | Ann Am Thorac Soc | pmid:27788025 |
| Morimoto K et al. | Macrolide-Resistant Mycobacterium avium Complex Lung Disease: Analysis of 102 Consecutive Cases. | 2016 | Ann Am Thorac Soc | pmid:27513168 |
| Pathak V et al. | Macrolide use leads to clinical and radiological improvement in patients with cryptogenic organizing pneumonia. | 2014 | Ann Am Thorac Soc | pmid:24460438 |
| Lee G et al. | Nodular bronchiectatic Mycobacterium avium complex pulmonary disease. Natural course on serial computed tomographic scans. | 2013 | Ann Am Thorac Soc | pmid:23952847 |
| Tran TT and Quandalle P | [Treatment of perforated gastroduodenal ulcer by simple suture followed by Helicobacter pylori eradication]. | 2002 | Ann Chir | pmid:11833303 |
| Tran TT and Quandalle P | [Long term results of treatment by simple surgical closure of perforated gastroduodenal ulcer followed by eradication of Helicobacter pylori]. | 2006 | Ann Chir | pmid:16716245 |
| Flisch CW et al. | [A case of arthritis of the wrist caused by Mycobacterium marinum. Review of the literature]. | 1996 | Ann Chir Main Memb Super | pmid:9026056 |
| Kwon YH et al. | A Case of Skin and Soft Tissue Infection Caused by Mycobacterium abscessus. | 2009 | Ann Dermatol | pmid:20548866 |
| Cho AY et al. | Identification of Cutaneous Mycobacterium massiliense Infections Associated with Repeated Surgical Procedures. | 2010 | Ann Dermatol | pmid:20548899 |
| Wastiaux H et al. | [Bursitis due to Mycobacterium intracellulare in an immunocompetent patient]. | 2008 Jun-Jul | Ann Dermatol Venereol | pmid:18598800 |
| Radouane N et al. | [Generalized chromomycosis caused by Phialophora verrucosa]. | 2013 | Ann Dermatol Venereol | pmid:23466152 |
| Huynh VA et al. | [Fixed drug eruption to clarithromycin: The importance of challenge tests in diagnosis]. | 2016 | Ann Dermatol Venereol | pmid:27080820 |
| Domergue Thân Trong E et al. | [Mycobacterium kansasii skin infection at insulin injection sites]. | 2001 | Ann Dermatol Venereol | pmid:11319391 |
| Bordet AL et al. | [Mycobacterium chelonae cutaneous infection: efficacy of prolonged treatment by clarithromycin]. | 1997 | Ann Dermatol Venereol | pmid:9686059 |
| Régnier S et al. | [Treatment of cutaneous infections due to Mycobacterium fortuitum: two cases]. | 2008 Aug-Sep | Ann Dermatol Venereol | pmid:18789296 |
| Sambourg E et al. | [Paradoxical reactions and responses during antibiotic treatment for Mycobacterium ulcerans infection (Buruli ulcer). Four cases from French Guiana]. | Ann Dermatol Venereol | pmid:24951139 | |
| Dupin N | [Paradoxal cultures]. | Ann Dermatol Venereol | pmid:24951138 | |
| Leiba A et al. | An unusual case of hypoglycemia in a diabetic patient. | 2004 | Ann Emerg Med | pmid:15460592 |
| Kundu S et al. | Clarithromycin-induced ventricular tachycardia. | 1997 | Ann Emerg Med | pmid:9326871 |
| Karne SS et al. | Mycobacterium avium-intracellulare brain abscess in HIV-positive patient. | 2012 | Ann Indian Acad Neurol | pmid:22412276 |
| Shojaei H et al. | Chronic pulmonary disease due to Mycobacterium monacense infection: the first case from Iran. | 2012 | Ann Lab Med | pmid:22259785 |
| Choi SJ et al. | The prevalence of vaginal microorganisms in pregnant women with preterm labor and preterm birth. | 2012 | Ann Lab Med | pmid:22563554 |
| Lee SH et al. | The drug resistance profile of Mycobacterium abscessus group strains from Korea. | 2014 | Ann Lab Med | pmid:24422193 |
| Hong SK et al. | First case of Mycobacterium longobardum infection. | 2013 | Ann Lab Med | pmid:24003427 |
| Granier H et al. | [Mycobacterium chelonei arthritis in an immunosuppressed patient. Efficacy of the treatment with clarithromycin]. | 1993 | Ann Med Interne (Paris) | pmid:8141516 |
| Arakawa R et al. | No inhibitory effect on P-glycoprotein function at blood-brain barrier by clinical dose of clarithromycin: a human PET study with [¹¹C]verapamil. | 2010 | Ann Nucl Med | pmid:20069466 |
| Saint-Blancard P et al. | [Cutaneous nodular infection with hemopathy]. | 2000 | Ann Pathol | pmid:11015652 |
| Tietz A et al. | Fulminant liver failure associated with clarithromycin. | 2003 | Ann Pharmacother | pmid:12503933 |
| Kadayifçi A et al. | Clarithromycin-induced fever in a patient with Helicobacter pylori gastritis. | 1997 | Ann Pharmacother | pmid:9184727 |
| Fraser LA et al. | Calcium channel blocker-clarithromycin drug interaction did not increase the risk of nonvertebral fracture: a population-based study. | 2015 | Ann Pharmacother | pmid:25429094 |
| Gerónimo-Pardo M et al. | Clarithromycin-nifedipine interaction as possible cause of vasodilatory shock. | 2005 | Ann Pharmacother | pmid:15703161 |
| Gooderham MJ et al. | Concomitant digoxin toxicity and warfarin interaction in a patient receiving clarithromycin. | 1999 Jul-Aug | Ann Pharmacother | pmid:10466907 |
| Greco S et al. | Glossitis, stomatitis, and black tongue with lansoprazole plus clarithromycin and other antibiotics. | 1997 | Ann Pharmacother | pmid:9416400 |
| Rollot F et al. | Acute colchicine intoxication during clarithromycin administration. | 2004 | Ann Pharmacother | pmid:15494379 |
| Ibrahim RB et al. | Tacrolimus-clarithromycin interaction in a patient receiving bone marrow transplantation. | 2002 | Ann Pharmacother | pmid:12452763 |
| Kahri AJ et al. | Rhabdomyolysis associated with concomitant use of simvastatin and clarithromycin. | 2004 | Ann Pharmacother | pmid:14966253 |
| Burgess DS et al. | A time-kill evaluation of clarithromycin and azithromycin against two extracellular pathogens and the development of resistance. | 1999 | Ann Pharmacother | pmid:10630825 |
| Sturgill MG and Rapp RP | Clarithromycin: review of a new macrolide antibiotic with improved microbiologic spectrum and favorable pharmacokinetic and adverse effect profiles. | 1992 | Ann Pharmacother | pmid:1421677 |
| Giannattasio A et al. | Steroid therapy for a case of severe drug-induced cholestasis. | 2006 | Ann Pharmacother | pmid:16720710 |
| Tracy TS and Johns M | Comment: delirium probably induced by clarithromycin in a patient receiving fluoxetine. | 1996 | Ann Pharmacother | pmid:8893135 |
| Gray VS | Syncopal episodes associated with cisapride and concurrent drugs. | 1998 | Ann Pharmacother | pmid:9640482 |
| Nawarskas JJ et al. | Digoxin toxicity secondary to clarithromycin therapy. | 1997 Jul-Aug | Ann Pharmacother | pmid:9220047 |
| Recker MW and Kier KL | Potential interaction between clarithromycin and warfarin. | 1997 | Ann Pharmacother | pmid:9296238 |
| Laberge P and Martineau P | Clarithromycin-induced digoxin intoxication. | 1997 | Ann Pharmacother | pmid:9296239 |