clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
|---|
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
|---|
What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with clarithromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (5)
- Drug Metab. Dispos. (1)
- FEMS Immunol. Med. Microbiol. (1)
- Others (5)
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Di Mario F et al. | Use of lactoferrin for Helicobacter pylori eradication. Preliminary results. | J. Clin. Gastroenterol. | pmid:12702979 | |
| Monego F et al. | Molecular identification and typing of Mycobacterium massiliense isolated from postsurgical infections in Brazil. | Braz J Infect Dis | pmid:22230849 | |
| Kim MD et al. | Ergotamine-induced upper extremity ischemia: a case report. | Korean J Radiol | pmid:15968153 | |
| Kekilli M et al. | Inefficacy of triple therapy and comparison of two different bismuth-containing quadruple regimens as a firstline treatment option for helicobacter pylori. | Saudi J Gastroenterol | pmid:27748322 | |
| Ikeda H et al. | Severe Disseminated Mycobacterium avium Infection in a Patient with a Positive Serum Autoantibody to Interferon-γ. | Intern. Med. | pmid:27746449 | |
| Walrave TR et al. | [Mania induced by antibiotic therapy]. | Tijdschr Psychiatr | pmid:27527887 | |
| Set R and Shastri J | Laboratory aspects of clinically significant rapidly growing mycobacteria. | Indian J Med Microbiol | pmid:22120792 | |
| Colomina RodrÃguez J et al. | [Impact of Integrated Model for Rational Use of Antibiotics in a health area (project MIURA)]. | Rev. Esp. Salud Publica | pmid:20661527 | |
| Mégraud F | [Helicobacter pylori infection: Review and practice]. | Presse Med | pmid:20627443 | |
| Vicente R et al. | [Helicobacter pylori eradication in patients with peptic ulcer after two treatment failures: a prospective culture-guided study]. | Gastroenterol Hepatol | pmid:12139836 | |
| Yoon HJ et al. | Nontuberculous mycobacterial tenosynovitis in the hand: two case reports with the MR imaging findings. | Korean J Radiol | pmid:22043158 | |
| Bennie CJ et al. | In vitro interaction of some drug combinations to inhibit rapidly growing mycobacteria isolates from cats and dogs and these isolates' susceptibility to cefovecin and clofazimine. | Aust. Vet. J. | pmid:25622709 | |
| Melo-Cristino J et al. | [Antimicrobial susceptibility of Streptococcus pyogenes, Haemophilus influenzae, Streptococcus pneumoniae and Moraxella catarrhalis from community acquired respiratory infections in 2000]. | Acta Med Port | pmid:11878155 | |
| Horiguchi T et al. | Antibacterial activity and clinical efficacy of sparfloxacin in Mycobacterium avium-intracellulare complex infection. | J. Int. Med. Res. | pmid:15458286 | |
| Roig J et al. | 13--Antibiotic therapy of community-acquired pneumonia (CAP) caused by atypical agents. | Med Mal Infect | pmid:17095177 | |
| Bachir M et al. | Primary antibiotic resistance and its relationship with cagA and vacA genes in Helicobacter pylori isolates from Algerian patients. | Braz. J. Microbiol. | pmid:29452847 | |
| Solé López J et al. | [Consumption of antibiotics and their possible relationship with bacterial resistance in the "Costa de Ponent" health region: analysis of evolution through the initial and end periods of the last decade]. | Aten Primaria | pmid:15274900 | |
| Issa H et al. | Bleeding duodenal ulcer after Roux-en-Y gastric bypass surgery: the value of laparoscopic gastroduodenoscopy. | Ann Saudi Med | pmid:20103961 | |
| Mishra A et al. | A rare debilitating neurological adverse effect of ranolazine due to drug interaction with clarithromycin. | Indian J Pharmacol | pmid:25298587 | |
| Lew EA | Clarithromycin, lansoprazole, and metronidazole eradicated Helicobacter pylori infection in chronic renal insufficiency. | ACP J. Club | pmid:15122860 | |
| Lindeboom JA | Facial Skin Lesions in Children Caused by Nontuberculous Mycobacteria. | Pediatr Dermatol | pmid:26823205 | |
| Beck J | Efficacy of esomeprazole in patients with acid-peptic disorders. | Gastroenterol Nurs | pmid:15082946 | |
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| Wang J et al. | Two-week triple therapy has a higher Helicobacter pylori eradication rate than 1-week therapy: A single-center randomized study. | Saudi J Gastroenterol | pmid:26655129 | |
| Pellicano R and Fagoonee S | One or two weeks of treatment with Helicobacter Pylori ''standard'' triple therapy in the year 2015? | Saudi J Gastroenterol | pmid:26655127 | |
| Alboraie M et al. | Quadruple therapy versus standard triple therapy for eradication of Helicobacter pylori in Kuwait. | Arab J Gastroenterol | pmid:26611765 | |
| Atukorale V et al. | An unusual antibiotic susceptibility pattern in a strain isolated from the chesapeake bay. | Int J Mycobacteriol | pmid:28317803 | |
| Gościniak G et al. | Frequency of infection with Helicobacter pylori isolates of different antimicrobial profiles in children and adolescents: A preliminary study. | Adv Clin Exp Med | pmid:28791844 | |
| Sambourg E et al. | [Paradoxical reactions and responses during antibiotic treatment for Mycobacterium ulcerans infection (Buruli ulcer). Four cases from French Guiana]. | Ann Dermatol Venereol | pmid:24951139 | |
| Dupin N | [Paradoxal cultures]. | Ann Dermatol Venereol | pmid:24951138 | |
| Rush R and Sheth S | Fulminant toxoplasmic retinochoroiditis following intravitreal triamcinolone administration. | Indian J Ophthalmol | pmid:22446913 | |
| Cavkaytar O et al. | Testing for clarithromycin hypersensitivity: A diagnostic challenge in childhood. | J Allergy Clin Immunol Pract | pmid:26489714 | |
| Seitz CS et al. | Suspicion of macrolide allergy after treatment of infectious diseases including Helicobacter pylori: results of allergological testing. | Allergol Immunopathol (Madr) | pmid:21269750 | |
| Moreira A et al. | Is Helicobacter pylori infection associated with chronic idiopathic urticaria? | Allergol Immunopathol (Madr) | pmid:12890412 | |
| Cobos-Trigueros N et al. | [Macrolides and ketolides]. | Enferm. Infecc. Microbiol. Clin. | pmid:19625112 | |
| Lin TY et al. | An open-label, randomized comparison of levofloxacin and amoxicillin/clavulanate plus clarithromycin for the treatment of hospitalized patients with community-acquired pneumonia. | Chang Gung Med J | pmid:17939262 |