clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with clarithromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (2)
- Clin. Infect. Dis. (1)
- FEMS Immunol. Med. Microbiol. (1)
- Others (2)
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Treille S et al. | Kidney graft dysfunction after drug interaction between clarithromycin and cyclosporin. | 1996 | Nephrol. Dial. Transplant. | pmid:8672003 |
| Araki J et al. | [A case of Mounier-Kuhn syndrome]. | 1996 | Nippon Naika Gakkai Zasshi | pmid:8708483 |
| Lowe SH et al. | Uveitis during treatment of disseminated Mycobacterium avium-intracellulare complex infection with the combination of rifabutin, clarithromycin and ethambutol. | 1996 | Neth J Med | pmid:8710040 |
| Segreti J et al. | In vitro activity of macrolides against intracellular Legionella pneumophila. | 1996 | Diagn. Microbiol. Infect. Dis. | pmid:8902407 |
| Craig AM et al. | Decision analysis of Helicobacter pylori eradication therapy using omeprazole with either clarithromycin or amoxicillin. | 1996 | Pharmacoeconomics | pmid:10160472 |
| [Management of atypical Mycobacterium infections in AIDS-patients]. | 1996 | Internist (Berl) | pmid:9131082 | |
| Ednie LM et al. | Comparative activities of clarithromycin, erythromycin, and azithromycin against penicillin-susceptible and penicillin-resistant pneumococci. | 1996 | Antimicrob. Agents Chemother. | pmid:8843313 |
| Nash KA and Inderlied CB | Rapid detection of mutations associated with macrolide resistance in Mycobacterium avium complex. | 1996 | Antimicrob. Agents Chemother. | pmid:8807078 |
| Bock H and Mares A | [Good results with Helicobacter pylori eradication for treatment of non-ulcer dyspepsia]. | 1996 | Leber Magen Darm | pmid:9005302 |
| Tursi A et al. | Evaluation of the efficacy and tolerability of four different therapeutic regimens for the Helicobacter pylori eradication. | 1996 | Panminerva Med | pmid:9009677 |
| Kelleher P et al. | Uveitis associated with rifabutin and macrolide therapy for Mycobacterium avium intracellulare infection in AIDS patients. | 1996 | Genitourin Med | pmid:9038637 |
| Sjöström JE and Larsson H | Factors affecting growth and antibiotic susceptibility of Helicobacter pylori: effect of pH and urea on the survival of a wild-type strain and a urease-deficient mutant. | 1996 | J. Med. Microbiol. | pmid:8636959 |
| Clarithromycin and omeprazole for Helicobacter pylori. | 1996 | Med Lett Drugs Ther | pmid:8637481 | |
| Pozniak A and Nelson MR | Against the proposition: all patients with advanced HIV disease should be offered rifabutin prophylaxis. | 1996 | Genitourin Med | pmid:8976832 |
| Berger C et al. | Treatment of nontuberculous mycobacterial lymphadenitis with clarithromycin plus rifabutin. | 1996 | J. Pediatr. | pmid:8774511 |
| Sito E et al. | One week treatment with omeprazole, clarithromycin and tinidazole or lansoprazole, amoxicillin and metronidazole for cure of Helicobacter pylori infection in duodenal ulcer patients. | 1996 | J. Physiol. Pharmacol. | pmid:8777303 |
| Gabryelewicz A | Critical evaluation of the treatment of peptic ulcer diseases associated with Helicobacter pylori infection. | 1996 | J. Physiol. Pharmacol. | pmid:8777307 |
| Deltenre M et al. | Strategies for Helicobacter pylori eradication in 1995: a review of international and Belgian experience. | 1996 | J. Physiol. Pharmacol. | pmid:8777308 |
| Roesch W | Cost-effectiveness of H. pylori eradication. | 1996 | J. Physiol. Pharmacol. | pmid:8777309 |
| Giacometti A et al. | In-vitro activity of macrolides alone and in combination with artemisin, atovaquone, dapsone, minocycline or pyrimethamine against Cryptosporidium parvum. | 1996 | J. Antimicrob. Chemother. | pmid:8889715 |
| Tracy TS and Johns M | Comment: delirium probably induced by clarithromycin in a patient receiving fluoxetine. | 1996 | Ann Pharmacother | pmid:8893135 |
| Ghebremichael S et al. | Antimycobacterial synergism of clarithromycin and rifabutin. | 1996 | Scand. J. Infect. Dis. | pmid:8893404 |
| Yousfi MM et al. | Metronidazole, ranitidine and clarithromycin combination for treatment of Helicobacter pylori infection (modified Bazzoli's triple therapy). | 1996 | Aliment. Pharmacol. Ther. | pmid:8871452 |
| McLinn S and Williams D | Incidence of antibiotic-resistant Streptococcus pneumoniae and beta-lactamase-positive Haemophilus influenzae in clinical isolates from patients with otitis media. | 1996 | Pediatr. Infect. Dis. J. | pmid:8878239 |
| Jaup BH and Norrby A | Comparison of two low-dose one-week triple therapy regimens with and without metronidazole for cure of H. pylori infection. | 1996 | Aliment. Pharmacol. Ther. | pmid:8791950 |
| Weldon MJ et al. | A seven-day Helicobacter pylori treatment regimen using clarithromycin, omeprazole and tripotassium dicitrato bismuthate. | 1996 | Aliment. Pharmacol. Ther. | pmid:8791951 |
| Tursi A et al. | Low-dose omeprazole plus clarithromycin and either tinidazole or amoxycillin for Helicobacter pylori infection. | 1996 | Aliment. Pharmacol. Ther. | pmid:8791952 |
| Pierce M et al. | A randomized trial of clarithromycin as prophylaxis against disseminated Mycobacterium avium complex infection in patients with advanced acquired immunodeficiency syndrome. | 1996 | N. Engl. J. Med. | pmid:8663871 |
| Rastogi N et al. | In vitro activities of fourteen antimicrobial agents against drug susceptible and resistant clinical isolates of Mycobacterium tuberculosis and comparative intracellular activities against the virulent H37Rv strain in human macrophages. | 1996 | Curr. Microbiol. | pmid:8672093 |
| Naoki K et al. | [Two cases of pulmonary disease caused by Mycobacterium chelonae subsp. abscessus]. | 1996 | Nihon Kyobu Shikkan Gakkai Zasshi | pmid:8976085 |
| Iwata M et al. | [Bronchiolitis obliterans preceding rheumatoid arthritis: effect of clarithromycin]. | 1996 | Nihon Kyobu Shikkan Gakkai Zasshi | pmid:8976086 |
| Pinzani V et al. | [Occurrence of anterior uveitis in a HIV patient treated with rifabutin, ethambutol, clarithromycin]. | 1995 Sep-Oct | Therapie | pmid:8571297 |
| Dalston MO et al. | [Clarithromycin combined with pyrimethamine in cerebral toxoplasmosis--a report of 2 cases]. | 1995 Oct-Dec | Rev. Soc. Bras. Med. Trop. | pmid:8668843 |
| Sternon J et al. | Azithromycin compared with clarithromycin in the treatment of adult patients with acute purulent tracheobronchitis: a cost of illness study. | 1995 Nov-Dec | J. Int. Med. Res. | pmid:8746608 |
| Stein GE et al. | A preliminary study of clarithromycin versus doxycycline in the treatment of nongonococcal urethritis and mucopurulent cervicitis. | 1995 Nov-Dec | Pharmacotherapy | pmid:8602379 |
| Hashisaki GT | Update on macrolide antibiotics. | 1995 May-Jun | Am J Otolaryngol | pmid:7661309 |
| Kees F et al. | Serum and cellular pharmacokinetics of clarithromycin 500 mg q.d. and 250 mg b.i.d. in volunteers. | 1995 May-Jun | Infection | pmid:7499006 |
| Claussen DW | The most commonly prescribed medications in the United States: Part 3. | 1995 Jul-Aug | Gastroenterol Nurs | pmid:7654815 |
| Adamek RJ et al. | [Short-term triple therapy with pantoprazole, clarithromycin and metronidazole for the healing of Helicobacter pylori infection]. | 1995 | Dtsch. Med. Wochenschr. | pmid:7889816 |
| Matsiota-Bernard P et al. | Mycobacterium genavense infection in a patient with AIDS who was successfully treated with clarithromycin. | 1995 | Clin. Infect. Dis. | pmid:7548515 |
| Citron DM et al. | Activity of ampicillin/sulbactam, ticarcillin/clavulanate, clarithromycin, and eleven other antimicrobial agents against anaerobic bacteria isolated from infections in children. | 1995 | Clin. Infect. Dis. | pmid:7548597 |
| Labenz J and Börsch G | Toward an optimal treatment of Helicobacter pylori-positive peptic ulcers. | 1995 | Am. J. Gastroenterol. | pmid:7733070 |
| Tseng AL and Walmsley SL | Rifabutin-associated uveitis. | 1995 | Ann Pharmacother | pmid:8573961 |
| Moayyedi P et al. | Efficacy and optimum dose of omeprazole in a new 1-week triple therapy regimen to eradicate Helicobacter pylori. | 1995 | Eur J Gastroenterol Hepatol | pmid:8574714 |
| Cohen Y et al. | Use of normal C57BL/6 mice with established Mycobacterium avium infections as an alternative model for evaluation of antibiotic activity. | 1995 | Antimicrob. Agents Chemother. | pmid:7793882 |
| Furney SK et al. | Activities of rifabutin, clarithromycin, and ethambutol against two virulent strains of Mycobacterium avium in a mouse model. | 1995 | Antimicrob. Agents Chemother. | pmid:7793895 |
| Brown BA et al. | Clarithromycin-induced hepatotoxicity. | 1995 | Clin. Infect. Dis. | pmid:7795060 |
| New drug applications sought. | 1995 | AIDS Alert | pmid:11362777 | |
| Smart T | Cryptosporidiosis at ICAAC. | 1995 | GMHC Treat Issues | pmid:11362913 |
| Researchers find new drugs to fight MAC. | 1995 | AIDS Alert | pmid:11362925 |