clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with clarithromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Model | Cross reference | Weighted score | Related literatures |
---|
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
González Carro P et al. | [Efficacy of an ultrashort protocol in the eradication of Helicobacter pylori]. | 1998 | Rev Esp Enferm Dig | pmid:9780793 |
Gangadharam PR | Clarithromycin for non-mycobacterial diseases? | 1998 | Int. J. Tuberc. Lung Dis. | pmid:9783536 |
Hua J et al. | Characterization of clinical isolates of Helicobacter pylori in Singapore. | 1998 | Microbios | pmid:9785486 |
Sádaba B et al. | Concurrent clarithromycin and cyclosporin A treatment. | 1998 | J. Antimicrob. Chemother. | pmid:9786481 |
Finkenbine RD and Frye MD | Case of psychosis due to prednisone-clarithromycin interaction. | 1998 | Gen Hosp Psychiatry | pmid:9788033 |
Borody TJ | Helicobacter pylori eradication failure--'salvage' therapies needed. | 1998 | Ital J Gastroenterol Hepatol | pmid:9789131 |
Coudron PE and Stratton CW | The bactericidal activity of clarithromycin versus ampicillin alone and in combination with omeprazole and/or bismuth against clarithromycin-susceptible and clarithromycin-resistant strains of Helicobacter pylori. | 1998 | Diagn. Microbiol. Infect. Dis. | pmid:9791756 |
Niang M et al. | [Painful nodular lesions]. | 1998 | Rev Med Interne | pmid:9793156 |
Saika T et al. | [A mechanism of clarithromycin resistance in Helicobacter pylori]. | 1998 | Kansenshogaku Zasshi | pmid:9796191 |
Langan C et al. | Short-course cefuroxime axetil therapy in the treatment of acute exacerbations of chronic bronchitis. | 1998 Jul-Aug | Int. J. Clin. Pract. | pmid:9796558 |
Piccolomini R et al. | Bacteriostatic and bactericidal in vitro activities of clarithromycin and erythromycin against periodontopathic Actinobacillus actinomycetemcomitans. | 1998 | Antimicrob. Agents Chemother. | pmid:9797240 |
Horgen L et al. | Pulsed-exposure and postantibiotic leukocyte enhancement effects of amikacin, clarithromycin, clofazimine, and rifampin against intracellular Mycobacterium avium. | 1998 | Antimicrob. Agents Chemother. | pmid:9797242 |
Ouellet D et al. | Pharmacokinetic interaction between ritonavir and clarithromycin. | 1998 | Clin. Pharmacol. Ther. | pmid:9797791 |
Chodosh S et al. | Efficacy of oral ciprofloxacin vs. clarithromycin for treatment of acute bacterial exacerbations of chronic bronchitis. The Bronchitis Study Group. | 1998 | Clin. Infect. Dis. | pmid:9798025 |
Craft JC et al. | Clarithromycin resistance and susceptibility patterns of Mycobacterium avium strains isolated during prophylaxis for disseminated infection in patients with AIDS. | 1998 | Clin. Infect. Dis. | pmid:9798037 |
Shafran SD | Clarithromycin prophylaxis for disseminated Mycobacterium avium complex infection--efficacy and acquired resistance. | 1998 | Clin. Infect. Dis. | pmid:9798038 |
Cestari R | Ranitidine bismuth citrate (RBC) based triple therapy for 7 days is more effective than RBC plus clarithromycin for 14 days in dyspeptic patients with Helicobacter pylori infection. H. Pylori Lombardy Group. | 1998 | Aliment. Pharmacol. Ther. | pmid:9798804 |
Spadaccini A et al. | Triple regimens using lansoprazole or ranitidine bismuth citrate for Helicobacter pylori eradication. | 1998 | Aliment. Pharmacol. Ther. | pmid:9798805 |
Bortolotti M et al. | Effects of oral clarithromycin and amoxycillin on interdigestive gastrointestinal motility of patients with functional dyspepsia and Helicobacter pylori gastritis. | 1998 | Aliment. Pharmacol. Ther. | pmid:9798808 |
Hynes B | Contact granulomas. | 1998 | J Otolaryngol | pmid:9800633 |