| MeSH term | MeSH ID | Detail |
|---|---|---|
| Body Weight | D001835 | 333 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Insulin Resistance | D007333 | 99 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Hyperlipidemias | D006949 | 73 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Cystic Fibrosis | D003550 | 65 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Parkinson Disease | D010300 | 53 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Lupus Erythematosus, Systemic | D008180 | 43 associated lipids |
clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with clarithromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Formanoy E et al. | Tenosynovitis of the right hand. Mycobacterium kansasii. | 2013 | Neth J Med | pmid:24394739 |
| Patel AM et al. | Statin toxicity from macrolide antibiotic coprescription: a population-based cohort study. | 2013 | Ann. Intern. Med. | pmid:23778904 |
| Siamas K and Khachemoune A | Mycobacteria infection in an immunocompetent patient with no risk factors: evaluation and management of non-healing majocchi granuloma-type nodule. | 2013 | Dermatol. Online J. | pmid:24021439 |
| Xu Y et al. | Synthesis and antibacterial activity of novel modified 5-O-mycaminose 14-membered ketolides. | 2013 | Eur J Med Chem | pmid:24021890 |
| Ranganathan D et al. | Mycobacterium fortuitum peritonitis in a patient receiving continuous ambulatory peritoneal dialysis. | 2013 | Saudi J Kidney Dis Transpl | pmid:24029271 |
| Krashias G et al. | Prevalence of Helicobacter pylori cagA and vacA genes in Cypriot patients. | 2013 | J Infect Dev Ctries | pmid:24042099 |
| Lally L and Mannion L | The potential for antimicrobials to adversely affect mental state. | 2013 | BMJ Case Rep | pmid:23833088 |
| Nguyen L and Taylor-Gjevre RM | An emerging role for clarithromycin in adult-onset still disease? | 2013 | J Clin Rheumatol | pmid:24048102 |
| Murai A et al. | Mastitis caused by Mycobacterium kansasii infection in a dog. | 2013 | Vet Clin Pathol | pmid:23808608 |
| Trespalacios AA et al. | Phenotypic and genotypic analysis of clarithromycin-resistant Helicobacter pylori from Bogotá D.C., Colombia. | 2013 | J. Microbiol. | pmid:23990295 |
| Lee YC et al. | The benefit of mass eradication of Helicobacter pylori infection: a community-based study of gastric cancer prevention. | 2013 | Gut | pmid:22698649 |
| Saviola G et al. | Clarithromycin in rheumatoid arthritis: the addition to methotrexate and low-dose methylprednisolone induces a significant additive value--a 24-month single-blind pilot study. | 2013 | Rheumatol. Int. | pmid:23864141 |
| Amado-RodrÃguez L et al. | Anti-inflammatory effects of clarithromycin in ventilator-induced lung injury. | 2013 | Respir. Res. | pmid:23663489 |
| Pereira JM et al. | Interplay of degradation, dissolution and stabilization of clarithromycin and its amorphous solid dispersions. | 2013 | Mol. Pharm. | pmid:24116899 |
| Huang J et al. | Randomised controlled trial: sequential vs. standard triple therapy for Helicobacter pylori infection in Chinese children-a multicentre, open-labelled study. | 2013 | Aliment. Pharmacol. Ther. | pmid:24117692 |
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| Chen K et al. | Low dose macrolide administration for long term is effective for otitis media with effusion in children. | 2013 | Auris Nasus Larynx | pmid:22673738 |
| Drago F et al. | Acute autoimmune thrombocytopenia and worsening of dermatomyositis after administration of clarithromycin. | 2013 | J. Am. Acad. Dermatol. | pmid:24124859 |
| Guo L et al. | Refining the human iPSC-cardiomyocyte arrhythmic risk assessment model. | 2013 | Toxicol. Sci. | pmid:24052561 |
| Wang S et al. | A supra-monolayer nanopattern for organic nanoparticle array deposition. | 2013 | ACS Appl Mater Interfaces | pmid:23480527 |
| Raghunatha K and George JP | Periodontal tissue and serum concentration of clarithromycin after systemic administration in patients affected by chronic periodontitis. | 2013 | J. Periodontol. | pmid:23451987 |
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| Morse AL et al. | A randomized controlled trial comparing sequential with triple therapy for Helicobacter pylori in an Aboriginal community in the Canadian North. | 2013 | Can. J. Gastroenterol. | pmid:24340314 |
| Pan W et al. | Effects of clopidogrel and clarithromycin on the disposition of sibutramine and its active metabolites M1 and M2 in relation to CYP2B6*6 polymorphism. | 2013 | Xenobiotica | pmid:22830954 |
| Evdokimova AG et al. | [New approaches to therapy of Helicobacterpylori infection (by the materials of the Maastricht Consensus-IV, Florence, 2010)]. | 2013 | Antibiot. Khimioter. | pmid:24640139 |
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| Shinahara W et al. | Immunomodulator clarithromycin enhances mucosal and systemic immune responses and reduces re-infection rate in pediatric patients with influenza treated with antiviral neuraminidase inhibitors: a retrospective analysis. | 2013 | PLoS ONE | pmid:23875018 |
| Friedman ND et al. | Mycobacterium ulcerans disease: experience with primary oral medical therapy in an Australian cohort. | 2013 | PLoS Negl Trop Dis | pmid:23875050 |
| Suzuki RB et al. | Low Helicobacter pylori primary resistance to clarithromycin in gastric biopsy specimens from dyspeptic patients of a city in the interior of São Paulo, Brazil. | 2013 | BMC Gastroenterol | pmid:24305035 |
| Yano K et al. | Clinical outcome of the chronic flexor tenosynovitis in the hand caused by non-tuberculous mycobacterium treated by extensive tenosynovectomy and drugs. | 2013 | J Plast Surg Hand Surg | pmid:23875916 |
| Trifan A et al. | Pseudomembranous colitis associated with a triple therapy for Helicobacter pylori eradication. | 2013 | World J. Gastroenterol. | pmid:24259981 |
| Laving A et al. | Effectiveness of sequential v. standard triple therapy for treatment of Helicobacter pylori infection in children in Nairobi, Kenya. | 2013 | S. Afr. Med. J. | pmid:24300630 |
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| Lee HJ et al. | Eradication of Helicobacter pylori according to 23S ribosomal RNA point mutations associated with clarithromycin resistance. | 2013 | J. Infect. Dis. | pmid:23801607 |
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| Bismuth + metronidazole + tetracycline. Why risk adding bismuth? | 2013 | Prescrire Int | pmid:23662315 | |
| Zhuo FL et al. | Clinical isolates of Mycobacterium abscessus in Guangzhou area most possibly from the environmental infection showed variable susceptibility. | 2013 | Chin. Med. J. | pmid:23673103 |
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| Rossi A et al. | BiRd (clarithromycin, lenalidomide, dexamethasone): an update on long-term lenalidomide therapy in previously untreated patients with multiple myeloma. | 2013 | Blood | pmid:23299315 |
| Andersen JT et al. | Clarithromycin in early pregnancy and the risk of miscarriage and malformation: a register based nationwide cohort study. | 2013 | PLoS ONE | pmid:23301061 |
| Kwak HM et al. | The efficacy of cefazolin plus macrolide (erythromycin or clarithromycin) versus cefazolin alone in neonatal morbidity and placental inflammation for women with preterm premature rupture of membranes. | 2013 | Placenta | pmid:23465535 |
| Huang HC et al. | Primary central nervous system diffuse large B cell lymphoma transformed from orbital mucosa-associated lymphoid tissue lymphoma: complete response to combined intrathecal and systemic rituximab. | 2013 | Ann. Hematol. | pmid:23242476 |
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| Liang JH et al. | Synthesis, antibacterial activity and docking of 14-membered 9-O-(3-arylalkyl) oxime 11,12-cyclic carbonate ketolides. | 2013 | Eur J Med Chem | pmid:23202851 |
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| Nakamura Y et al. | Optimal duration of macrolide treatment for chronic sinusitis after endoscopic sinus surgery. | 2013 | Auris Nasus Larynx | pmid:23107100 |
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| Koh WJ et al. | Reply: drug concentration monitoring in Mycobacterium avium lung disease: problems with methods and conclusions. | 2013 | Am. J. Respir. Crit. Care Med. | pmid:23577353 |
| Schmitt BH et al. | PCR detection of clarithromycin-susceptible and -resistant Helicobacter pylori from formalin-fixed, paraffin-embedded gastric biopsies. | 2013 | Mod. Pathol. | pmid:23579617 |
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| Marin AC et al. | A review of rescue regimens after clarithromycin-containing triple therapy failure (for Helicobacter pylori eradication). | 2013 | Expert Opin Pharmacother | pmid:23537368 |
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| Moriya S et al. | Macrolide antibiotics block autophagy flux and sensitize to bortezomib via endoplasmic reticulum stress-mediated CHOP induction in myeloma cells. | 2013 | Int. J. Oncol. | pmid:23546223 |
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