| MeSH term | MeSH ID | Detail |
|---|---|---|
| Body Weight | D001835 | 333 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Insulin Resistance | D007333 | 99 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Hyperlipidemias | D006949 | 73 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Cystic Fibrosis | D003550 | 65 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Parkinson Disease | D010300 | 53 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Lupus Erythematosus, Systemic | D008180 | 43 associated lipids |
clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with clarithromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (2)
- Clin. Infect. Dis. (1)
- FEMS Immunol. Med. Microbiol. (1)
- Others (2)
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Terashima T et al. | Pulmonary infection due to Mycobacterium xenopi. | 1994 | Intern. Med. | pmid:8000103 |
| Fish DN et al. | Penetration of clarithromycin into lung tissues from patients undergoing lung resection. | 1994 | Antimicrob. Agents Chemother. | pmid:8031063 |
| Thijs JC et al. | Short report: clarithromycin, an alternative to metronidazole in the triple therapy of Helicobacter pylori infection. | 1994 | Aliment. Pharmacol. Ther. | pmid:8186339 |
| Gelber RH et al. | Minimal bactericidal concentration of clarithromycin against M. leprae. | 1994 | Int. J. Lepr. Other Mycobact. Dis. | pmid:8189083 |
| Xiong JH et al. | Further study of the effectiveness of single doses of clarithromycin and minocycline against Mycobacterium leprae in mice. | 1994 | Int. J. Lepr. Other Mycobact. Dis. | pmid:8189087 |
| Paffetti A et al. | [Clarithromycin in pediatric age. Personal experience]. | 1994 | Minerva Pediatr. | pmid:8084327 |
| Saran BR et al. | Hypopyon uveitis in patients with acquired immunodeficiency syndrome treated for systemic Mycobacterium avium complex infection with rifabutin. | 1994 | Arch. Ophthalmol. | pmid:8085960 |
| Yew WW et al. | Cholestatic hepatitis in a patient who received clarithromycin therapy for a Mycobacterium chelonae lung infection. | 1994 | Clin. Infect. Dis. | pmid:8086541 |
| Zahid MA et al. | Mycobacterium chelonae (M. chelonae subspecies chelonae): report of a patient with a sporotrichoid presentation who was successfully treated with clarithromycin and ciprofloxacin. | 1994 | Clin. Infect. Dis. | pmid:8086568 |
| Gad A and Unge P | Antibacterial therapy of Helicobacter pylori-associated peptic ulcer disease: a new strategy. The Swedes go for it. | 1994 | J. Clin. Gastroenterol. | pmid:7930437 |
| Braegger CP and Nadal D | Clarithromycin and pseudomembranous enterocolitis. | 1994 | Lancet | pmid:7904702 |
| Nishimura M et al. | [Therapeutic study on biofilm of the urinary tract using a severely complicated bladder model (biofilm model of the urinary tract)--experimental study using an automatic simulator of urinary antimicrobial agent concentration, and clinical study]. | 1994 | Kansenshogaku Zasshi | pmid:7909830 |
| Labenz J | [Helicobacter pylori therapy with omeprazole and clarithromycin: current status]. | 1994 | Leber Magen Darm | pmid:7968179 |
| Oteo JA et al. | Clarithromycin-induced thrombocytopenic purpura. | 1994 | Clin. Infect. Dis. | pmid:7888564 |
| Shafran SD et al. | Uveitis and pseudojaundice during a regimen of clarithromycin, rifabutin, and ethambutol. MAC Study Group of the Canadian HIV Trials Network. | 1994 | N. Engl. J. Med. | pmid:8284019 |
| Meier A et al. | Identification of mutations in 23S rRNA gene of clarithromycin-resistant Mycobacterium intracellulare. | 1994 | Antimicrob. Agents Chemother. | pmid:8192472 |
| Labenz J et al. | [Omeprazole modified antibiotic therapy of Helicobacter pylori infection: can clarithromycin be replaced by roxithromycin?]. | 1994 | Leber Magen Darm | pmid:8196468 |
| Chan GP et al. | Clinical trial of clarithromycin for lepromatous leprosy. | 1994 | Antimicrob. Agents Chemother. | pmid:8203847 |
| Marco ML et al. | [Rhodococcus equi pneumonia in patients with AIDS]. | 1994 | Arch. Bronconeumol. | pmid:7827773 |
| Ferrari SL et al. | The interaction between clarithromycin and cyclosporine in kidney transplant recipients. | 1994 | Transplantation | pmid:7940695 |
| Tomono K | [Therapeutic efficacy of macrolide in pulmonary nontuberculous mycobacteriosis]. | 1994 | Kekkaku | pmid:7837727 |
| Sanchez T et al. | Quantitation of mycobacteria in blood specimens from patients with AIDS. | 1994 | Tuber. Lung Dis. | pmid:7841433 |
| Sungur C | Acute rheumatic fever despite clarithromycin treatment of beta-hemolytic streptococcal tonsillitis. | 1994 | Ann Pharmacother | pmid:7841580 |
| Maass M and Dalhoff K | [Isolation of Chlamydia pneumoniae in atypical pneumonia]. | 1994 | Dtsch. Med. Wochenschr. | pmid:7956770 |
| Verbist L and Dhoore F | In vitro susceptibility of recently isolated respiratory tract pathogens to minocycline and comparable antibiotics. A multicentre study. | 1994 | Acta Clin Belg | pmid:7871933 |
| Wüst J and Hardegger U | Penetration of clarithromycin into human saliva. | 1993 Sep-Oct | Chemotherapy | pmid:8370320 |
| Scaglione F et al. | A new model examining intracellular and extracellular activity of amoxicillin, azithromycin, and clarithromycin in infected cells. | 1993 Nov-Dec | Chemotherapy | pmid:8222870 |
| Ohmori S et al. | Effects of clarithromycin and its metabolites on the mixed function oxidase system in hepatic microsomes of rats. | 1993 Mar-Apr | Drug Metab. Dispos. | pmid:8097709 |
| Wallace RJ et al. | Drug intolerance to high-dose clarithromycin among elderly patients. | 1993 Mar-Apr | Diagn. Microbiol. Infect. Dis. | pmid:8477575 |
| Adam D | Clarithromycin 250 mg b.i.d. for 5 or 10 days in the treatment of adult patients with purulent bronchitis. | 1993 Jul-Aug | Infection | pmid:8225636 |
| Coles SJ et al. | A comparative study of clarithromycin and amoxycillin suspensions in the treatment of pediatric patients with acute otitis media. | 1993 Jul-Aug | Infection | pmid:8225637 |
| Miller CA | Infections, resistant microbes, and older adults. | 1993 Jan-Feb | Geriatr Nurs | pmid:8383085 |
| Ritchie DJ et al. | In vitro activity of clarithromycin, cefprozil, and other common oral antimicrobial agents against gram-positive and gram-negative pathogens. | 1993 Jan-Feb | Clin Ther | pmid:8458040 |
| Albani F et al. | Clarithromycin-carbamazepine interaction: a case report. | 1993 Jan-Feb | Epilepsia | pmid:8422851 |
| Sader HS et al. | In vitro activity of cefpodoxime compared with other oral cephalosporins tested against 5556 recent clinical isolates from five medical centers. | 1993 Aug-Sep | Diagn. Microbiol. Infect. Dis. | pmid:8243035 |
| Clarithromycin effectively treats infection in AIDS patients. | 1993 | Oncology (Williston Park, N.Y.) | pmid:8512782 | |
| Romand S et al. | In vitro and in vivo activities of the hydroxynaphthoquinone atovaquone alone or combined with pyrimethamine, sulfadiazine, clarithromycin, or minocycline against Toxoplasma gondii. | 1993 | Antimicrob. Agents Chemother. | pmid:8285620 |
| Schmidt T et al. | Clarithromycin lacks bactericidal activity in cerebrospinal fluid in experimental pneumococcal meningitis. | 1993 | J. Antimicrob. Chemother. | pmid:8288505 |
| Walker LL et al. | Clarithromycin is bactericidal against strains of Mycobacterium leprae resistant and susceptible to dapsone and rifampin. | 1993 | Int. J. Lepr. Other Mycobact. Dis. | pmid:8326182 |
| Ji B et al. | Powerful bactericidal activities of clarithromycin and minocycline against Mycobacterium leprae in lepromatous leprosy. | 1993 | J. Infect. Dis. | pmid:8257487 |
| Scaglione F et al. | The postantibiotic effect of clarithromycin and its major human metabolite, 14-hydroxy clarithromycin. | 1993 | J. Antimicrob. Chemother. | pmid:8262876 |
| Guay DR and Craft JC | Overview of the pharmacology of clarithromycin suspension in children and a comparison with that in adults. | 1993 | Pediatr. Infect. Dis. J. | pmid:8295810 |
| Hebert AA et al. | Comparative safety and efficacy of clarithromycin and cefadroxil suspensions in the treatment of mild to moderate skin and skin structure infections in children. | 1993 | Pediatr. Infect. Dis. J. | pmid:8295811 |
| Pukander JS et al. | Clarithromycin vs. amoxicillin suspensions in the treatment of pediatric patients with acute otitis media. | 1993 | Pediatr. Infect. Dis. J. | pmid:8295812 |
| Klopman G et al. | Anti-Mycobacterium avium activity of quinolones: in vitro activities. | 1993 | Antimicrob. Agents Chemother. | pmid:8239587 |
| Esvant H et al. | [Primary prophylaxis of cerebral toxoplasmosis in AIDS with clarithromycin]. | 1993 | Presse Med | pmid:8337221 |
| Lederer J et al. | Clarithromycin treatment of posttraumatic Mycobacterium fortuitum wound infection. | 1993 | Pediatr. Infect. Dis. J. | pmid:8414785 |
| de Vega T et al. | Clarithromycin-induced leukocytoclastic vasculitis. | 1993 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:8404922 |
| Chu S et al. | Single- and multiple-dose pharmacokinetics of clarithromycin, a new macrolide antimicrobial. | 1993 | J Clin Pharmacol | pmid:8408732 |
| Heifets L et al. | Mycobacterium avium strains resistant to clarithromycin and azithromycin. | 1993 | Antimicrob. Agents Chemother. | pmid:8031351 |