clarithromycin

clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.

Cross Reference

Introduction

To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with clarithromycin?

clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with clarithromycin

MeSH term MeSH ID Detail
Abnormalities, Drug-Induced D000014 10 associated lipids
Abortion, Spontaneous D000022 12 associated lipids
Abscess D000038 13 associated lipids
Achlorhydria D000126 1 associated lipids
Actinomycetales Infections D000193 4 associated lipids
Adenocarcinoma D000230 166 associated lipids
Angina Pectoris D000787 27 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Arteriosclerosis D001161 86 associated lipids
Arthritis D001168 41 associated lipids
Arthritis, Infectious D001170 8 associated lipids
Bacterial Infections D001424 21 associated lipids
Bacteriuria D001437 7 associated lipids
Barrett Esophagus D001471 3 associated lipids
Bartonella Infections D001474 3 associated lipids
Body Weight D001835 333 associated lipids
Boutonneuse Fever D001907 5 associated lipids
Bradycardia D001919 13 associated lipids
Bronchial Spasm D001986 18 associated lipids
Bronchiectasis D001987 7 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with clarithromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with clarithromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with clarithromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with clarithromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with clarithromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with clarithromycin?

Mouse Model

Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).

Knock-out

Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).

Experimental Pneumococcal Meningitis

Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with clarithromycin

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Authors Title Published Journal PubMed Link
Karrow NA et al. Evaluation of the immunomodulatory effects of the macrolide antibiotic, clarithromycin, in female B6C3F1 mice: a 28-day oral gavage study. 2001 Drug Chem Toxicol pmid:11307632
Kodama M and Fujioka T [Eradication therapy of Helicobacter pylori infection]. 2001 Rinsho Byori pmid:11307304
Fukuda Y et al. [The history of Helicobacter pylori]. 2001 Rinsho Byori pmid:11307300
Maraki S et al. Prospective evaluation of the impact of amoxicillin, clarithromycin and their combination on human gastrointestinal colonization by Candida species. 2001 May-Jun Chemotherapy pmid:11306791
Braga PC et al. Bacterial adhesiveness: effects of the SH metabolite of erdosteine (mucoactive drug) plus clarithromycin versus clarithromycin alone. 2001 May-Jun Chemotherapy pmid:11306790
Bochud PY et al. Breakthrough Streptococcus pneumoniae meningitis during clarithromycin therapy for acute otitis media. 2001 Eur. J. Clin. Microbiol. Infect. Dis. pmid:11305469
Lombardi A et al. Antimicrobial activity of thiamphenicol-glycinate-acetylcysteinate and other drugs against Chlamydia pneumoniae. 2001 Arzneimittelforschung pmid:11304944
Avidan B et al. The effect of culture results for Helicobacter pylori on the choice of treatment following failure of initial eradication. 2001 Isr. Med. Assoc. J. pmid:11303370
Piccolomini R et al. In vitro activity of clarithromycin against intracellular Helicobacter pylori. 2001 Antimicrob. Agents Chemother. pmid:11302831
van Doorn LJ et al. Accurate prediction of macrolide resistance in Helicobacter pylori by a PCR line probe assay for detection of mutations in the 23S rRNA gene: multicenter validation study. 2001 Antimicrob. Agents Chemother. pmid:11302817
Blokh I et al. A rare case of osteomyelitis of the sternum in an adult with sickle cell disease. 2001 Hemoglobin pmid:11300345
Bhagat N et al. Rifabutin-associated hypopyon uveitis in human immunodeficiency virus-negative immunocompetent individuals. 2001 Ophthalmology pmid:11297492
Karia N and Aylward GW Postoperative proprionibacterium acnes endophthalmitis. 2001 Ophthalmology pmid:11297461
Ashitani J et al. Plasma and BAL fluid concentrations of antimicrobial peptides in patients with Mycobacterium avium-intracellulare infection. 2001 Chest pmid:11296180
Jeen YT et al. Differentiation between reinfection and recrudescence of helicobacter pylori strains using PCR-based restriction fragment length polymorphism analysis. 2001 Yonsei Med. J. pmid:11293500
Zwolińska-Wcisło M and Palka M [Principles of managing Helicobacter pylori infections. Guidelines of the European Society of Gastroenterology in Primary Health Care]. 2000 Prz. Lek. pmid:11293204
Shuster J Clarithromycin and CNS disturbances. 2001 Nursing pmid:11288564
Osato MS et al. Comparative efficacy of new investigational agents against Helicobacter pylori. 2001 Aliment. Pharmacol. Ther. pmid:11284777
Broutet N et al. cagA Status and eradication treatment outcome of anti-Helicobacter pylori triple therapies in patients with nonulcer dyspepsia. 2001 J. Clin. Microbiol. pmid:11283049
Chisholm SA et al. PCR-based diagnosis of Helicobacter pylori infection and real-time determination of clarithromycin resistance directly from human gastric biopsy samples. 2001 J. Clin. Microbiol. pmid:11283030
Ioannidou S et al. Antibiotic resistance rates and macrolide resistance phenotypes of viridans group streptococci from the oropharynx of healthy Greek children. 2001 Int. J. Antimicrob. Agents pmid:11282264
Fock KM et al. A randomised trial of amoxycillin versus clarithromycin in combination with omeprazole for eradication of Helicobacter pylori infection in Singapore. 2000 Singapore Med J pmid:11281438
Rathi P et al. Comparison of two regimens on eradication of Helicobacter pylori. 2000 J Assoc Physicians India pmid:11273492
Dogukan A et al. Acute fatal colchicine intoxication in a patient on continuous ambulatory peritoneal dialysis (CAPD). Possible role of clarithromycin administration. 2001 Clin. Nephrol. pmid:11269688
Olivier D [HIV: a guide on management of seropositive patients]. 2001 Presse Med pmid:11268903
Wexler HM et al. In vitro activity of telithromycin (HMR 3647) against 502 strains of anaerobic bacteria. 2001 J. Antimicrob. Chemother. pmid:11266423
Kim JJ et al. Analysis of metronidazole, clarithromycin and tetracycline resistance of Helicobacter pylori isolates from Korea. 2001 J. Antimicrob. Chemother. pmid:11266421
Endo H et al. Effects of lansoprazole, clarithromycin and pH gradient on uptake of [14C]amoxycillin into rat gastric tissue. 2001 J. Antimicrob. Chemother. pmid:11266411
Schulz S et al. Molecular diagnosis of a Mycobacterium chelonae infection. 2001 Pathol. Res. Pract. pmid:11261816
Schaumann R et al. Pericarditis after allogeneic peripheral blood stem cell transplantation caused by Legionella pneumophila (non-serogroup 1). 2001 Jan-Feb Infection pmid:11261761
Peña JA et al. Molecular resistance testing of Helicobacter pylori in gastric biopsies. 2001 Arch. Pathol. Lab. Med. pmid:11260622
Jang HS et al. Six cases of confluent and reticulated papillomatosis alleviated by various antibiotics. 2001 J. Am. Acad. Dermatol. pmid:11260541
Hamamoto Y et al. Fixed drug eruption due to clarithromycin. 2001 Clin. Exp. Dermatol. pmid:11260179
Casal M and Casal MM Multicenter study of incidence of Mycobacterium marinum in humans in Spain. 2001 Int. J. Tuberc. Lung Dis. pmid:11258515
Khor CJ et al. Recurrence of Helicobacter pylori infection and duodenal ulcer relapse, following successful eradication in an urban east Asian population. 2000 Singapore Med J pmid:11256345
Lutgen N et al. [Prevalence and treatment of Helicobacter pylori in gastro-duodenal ulcers. An experience in Liege]. 2001 Rev Med Liege pmid:11256133
Bindayna KM Antibiotic susceptibilities of Helicobacter pylori. 2001 Saudi Med J pmid:11255612
Vergassola R et al. [Chlamydia pneumoniae and myocardial infarction (CLINF). Preliminary randomized controlled study with clarithromycin. CLAINF protocol]. 2000 Minerva Cardioangiol pmid:11253326
Krasemann C et al. Evaluation of the clinical microbiology profile of moxifloxacin. 2001 Clin. Infect. Dis. pmid:11249830
Schentag JJ et al. What have we learned from pharmacokinetic and pharmacodynamic theories? 2001 Clin. Infect. Dis. pmid:11249828
Amábile-Cuevas CF et al. Comparative in vitro activity of moxifloxacin by E-test against Streptococcus pyogenes. 2001 Clin. Infect. Dis. pmid:11249826
Leung WK and Graham DY Clarithromycin for Helicobacter pylori infection. 2000 Expert Opin Pharmacother pmid:11249534
Yazawa N et al. The successful treatment of prurigo pigmentosa with macrolide antibiotics. 2001 Dermatology (Basel) pmid:11244235
Furuta T et al. Effect of genotypic differences in CYP2C19 on cure rates for Helicobacter pylori infection by triple therapy with a proton pump inhibitor, amoxicillin, and clarithromycin. 2001 Clin. Pharmacol. Ther. pmid:11240980
Cangelosi GA et al. Phenotypic consequences of red-white colony type variation in Mycobacterium avium. 2001 Microbiology (Reading, Engl.) pmid:11238960
Ishigo S et al. [The frequency of Streptococcus pneumoniae strains and sensitivity surveillance for several antibiotics in Gifu Prefecture]. 2000 Jpn J Antibiot pmid:11234221
Ozluer SM and De'Ambrosis BJ Mycobacterium abscessus wound infection. 2001 Australas. J. Dermatol. pmid:11233716
Maconi G et al. Do some patients with Helicobacter pylori infection benefit from an extension to 2 weeks of a proton pump inhibitor-based triple eradication therapy? 2001 Am. J. Gastroenterol. pmid:11232676
Kato K et al. A case of gastric plasmacytoma associated with Helicobacter pylori infection: improvement of abnormal endoscopic and EUS findings after H. pylori eradication. 2001 Gastrointest. Endosc. pmid:11231401
Kim HS et al. Comparison of the efficacy and safety of different formulations of omeprazole-based triple therapies in the treatment of Helicobacter pylori-positive peptic ulcer. 2001 J. Gastroenterol. pmid:11227677