| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Tuberculosis | D014376 | 20 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Nocardia Infections | D009617 | 6 associated lipids |
| Diarrhea | D003967 | 32 associated lipids |
| Hearing Loss, Sensorineural | D006319 | 8 associated lipids |
| Otitis Media | D010033 | 12 associated lipids |
| Carcinoma, Basal Cell | D002280 | 6 associated lipids |
| Arrhythmias, Cardiac | D001145 | 42 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Bacterial Infections | D001424 | 21 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Lupus Erythematosus, Systemic | D008180 | 43 associated lipids |
| Stomach Diseases | D013272 | 7 associated lipids |
| Lung Diseases | D008171 | 37 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Skin Neoplasms | D012878 | 12 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Leishmaniasis, Visceral | D007898 | 13 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with clarithromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Grunden JW and Fisher KA | Lovastatin-induced rhabdomyolysis possibly associated with clarithromycin and azithromycin. | 1997 Jul-Aug | Ann Pharmacother | pmid:9220046 |
| Kadayifçi A et al. | Clarithromycin-induced fever in a patient with Helicobacter pylori gastritis. | 1997 | Ann Pharmacother | pmid:9184727 |
| Fraser LA et al. | Calcium channel blocker-clarithromycin drug interaction did not increase the risk of nonvertebral fracture: a population-based study. | 2015 | Ann Pharmacother | pmid:25429094 |
| Gerónimo-Pardo M et al. | Clarithromycin-nifedipine interaction as possible cause of vasodilatory shock. | 2005 | Ann Pharmacother | pmid:15703161 |
| Nakamura H et al. | Effect of levofloxacin on theophylline clearance during theophylline and clarithromycin combination therapy. | 2001 | Ann Pharmacother | pmid:11408986 |
| Wintermeyer SM et al. | Dirithromycin: a new macrolide. | 1996 | Ann Pharmacother | pmid:8893122 |
| Juurlink DN and Ito S | Comment: clarithromycin-digoxin interaction. | 1999 | Ann Pharmacother | pmid:10630847 |
| Rao KB et al. | Enhanced hypoprothrombinemia with warfarin due to azithromycin. | 2004 | Ann Pharmacother | pmid:15084685 |
| Basyigit I et al. | The effect of clarithromycin on inflammatory markers in chronic obstructive pulmonary disease: preliminary data. | 2004 | Ann Pharmacother | pmid:15252191 |
| Varner TR et al. | Role of rifampin-based combination therapy for severe community-acquired Legionella pneumophila pneumonia. | 2011 | Ann Pharmacother | pmid:21775694 |
| Courter JD et al. | Increased clinical failures when treating acute otitis media with macrolides: a meta-analysis. | 2010 | Ann Pharmacother | pmid:20150506 |
| Pollak PT et al. | Delirium probably induced by clarithromycin in a patient receiving fluoxetine. | 1995 | Ann Pharmacother | pmid:7655131 |
| Rollot F et al. | Acute colchicine intoxication during clarithromycin administration. | 2004 | Ann Pharmacother | pmid:15494379 |
| Piquette RK | Torsade de pointes induced by cisapride/clarithromycin interaction. | 1999 | Ann Pharmacother | pmid:9972380 |
| Kahri AJ et al. | Rhabdomyolysis associated with concomitant use of simvastatin and clarithromycin. | 2004 | Ann Pharmacother | pmid:14966253 |
| Burgess DS et al. | A time-kill evaluation of clarithromycin and azithromycin against two extracellular pathogens and the development of resistance. | 1999 | Ann Pharmacother | pmid:10630825 |
| Grau E et al. | Interaction between clarithromycin and oral anticoagulants. | 1996 | Ann Pharmacother | pmid:8968465 |
| González Carro P et al. | Acute pancreatitis and modified-release clarithromycin. | 2004 | Ann Pharmacother | pmid:14755067 |
| Lee AJ and Maddix DS | Rhabdomyolysis secondary to a drug interaction between simvastatin and clarithromycin. | 2001 | Ann Pharmacother | pmid:11197581 |
| Sturgill MG and Rapp RP | Clarithromycin: review of a new macrolide antibiotic with improved microbiologic spectrum and favorable pharmacokinetic and adverse effect profiles. | 1992 | Ann Pharmacother | pmid:1421677 |
| Giannattasio A et al. | Steroid therapy for a case of severe drug-induced cholestasis. | 2006 | Ann Pharmacother | pmid:16720710 |
| Vangala R and Cernek PK | Hypersensitivity reaction to clarithromycin. | 1996 | Ann Pharmacother | pmid:8833572 |
| Sungur C | Acute rheumatic fever despite clarithromycin treatment of beta-hemolytic streptococcal tonsillitis. | 1994 | Ann Pharmacother | pmid:7841580 |
| Gray VS | Syncopal episodes associated with cisapride and concurrent drugs. | 1998 | Ann Pharmacother | pmid:9640482 |
| Nawarskas JJ et al. | Digoxin toxicity secondary to clarithromycin therapy. | 1997 Jul-Aug | Ann Pharmacother | pmid:9220047 |
| Widgerow AD et al. | Atypical Mycobacterium and breast surgery. | 1995 | Ann Plast Surg | pmid:7486746 |
| Issa H et al. | Bleeding duodenal ulcer after Roux-en-Y gastric bypass surgery: the value of laparoscopic gastroduodenoscopy. | Ann Saudi Med | pmid:20103961 | |
| Varghese B et al. | First case report of chronic pulmonary lung disease caused by Mycobacterium abscessus in two immunocompetent patients in Saudi Arabia. | Ann Saudi Med | pmid:22588446 | |
| Moosavian M et al. | Rapid detection of clarithromycin-resistant Helicobacter pylori in patients with dyspepsia by fluorescent in situ hybridization (FISH) compared with the E-test. | 2007 Mar-Apr | Ann Saudi Med | pmid:17356313 |
| Al-Benwan K et al. | Diagnosis of endocarditis caused by Mycobacterium abscessus. | 2010 Sep-Oct | Ann Saudi Med | pmid:20697162 |
| Kikuchi R et al. | A case of Good's syndrome: a rare acquired immunodeficiency associated with thymoma. | 2011 | Ann Thorac Cardiovasc Surg | pmid:21587135 |
| Wali S | Mycobacterium chelonae empyema with bronchopleural fistula in an immunocompetent patient. | 2009 | Ann Thorac Med | pmid:19881169 |
| Tanih NF et al. | Characterisation of the genes encoding resistance to metronidazole (rdxA and frxA) and clarithromycin (the 23S-rRNA genes) in South African isolates of Helicobacter pylori. | 2011 | Ann Trop Med Parasitol | pmid:21801504 |
| Tan HH et al. | Cutaneous Mycobacterium haemophilum infections in immunocompromised patients in a dermatology clinic in Singapore. | 2004 | Ann. Acad. Med. Singap. | pmid:15329772 |
| Lee HY et al. | Unresolving furunculosis in a diabetic patient: cutaneous Mycobacterium abscessus infection. | 2009 | Ann. Acad. Med. Singap. | pmid:19271048 |
| Amayasu H et al. | Clarithromycin suppresses bronchial hyperresponsiveness associated with eosinophilic inflammation in patients with asthma. | 2000 | Ann. Allergy Asthma Immunol. | pmid:10875487 |
| Dubini M et al. | Multiple drug allergy: A case of anaphylaxis to levofloxacin but tolerance to ciprofloxacin. | 2016 | Ann. Allergy Asthma Immunol. | pmid:27009438 |
| Fonseca-Aten M et al. | Effect of clarithromycin on cytokines and chemokines in children with an acute exacerbation of recurrent wheezing: a double-blind, randomized, placebo-controlled trial. | 2006 | Ann. Allergy Asthma Immunol. | pmid:17069099 |
| Hahn DL et al. | Evidence for Chlamydia pneumoniae infection in steroid-dependent asthma. | 1998 | Ann. Allergy Asthma Immunol. | pmid:9475566 |
| Swamy N et al. | Successful clarithromycin desensitization in a multiple macrolide-allergic patient. | 2010 | Ann. Allergy Asthma Immunol. | pmid:21130389 |
| McCarty JM and Pierce PF | Five days of cefprozil versus 10 days of clarithromycin in the treatment of an acute exacerbation of chronic bronchitis. | 2001 | Ann. Allergy Asthma Immunol. | pmid:11686426 |
| Spahn JD et al. | Clarithromycin potentiates glucocorticoid responsiveness in patients with asthma: results of a pilot study. | 2001 | Ann. Allergy Asthma Immunol. | pmid:11770698 |
| Mori F et al. | Sensitivity and specificity of skin tests in the diagnosis of clarithromycin allergy. | 2010 | Ann. Allergy Asthma Immunol. | pmid:20486332 |
| Morisset J et al. | A case of difficult-to-treat eosinophilic asthma controlled with clarithromycin. | 2012 | Ann. Allergy Asthma Immunol. | pmid:22727169 |
| Randhawa I and Klaustermeyer WB | Oral corticosteroid-dependent asthma: a 30-year review. | 2007 | Ann. Allergy Asthma Immunol. | pmid:17941275 |
| Sevin E et al. | [Helicobacter pylori: identification and detection of clarithromycin resistance by gene amplification]. | 2000 Jan-Feb | Ann. Biol. Clin. (Paris) | pmid:10673617 |
| Akram FE et al. | A combination of silver nanoparticles and visible blue light enhances the antibacterial efficacy of ineffective antibiotics against methicillin-resistant Staphylococcus aureus (MRSA). | 2016 | Ann. Clin. Microbiol. Antimicrob. | pmid:27530257 |
| Chen J et al. | Application of next-generation sequencing to characterize novel mutations in clarithromycin-susceptible Helicobacter pylori strains with A2143G of 23S rRNA gene. | 2018 | Ann. Clin. Microbiol. Antimicrob. | pmid:29562911 |
| Myers AL et al. | Genetic commonality of macrolide-resistant group A beta hemolytic streptococcus pharyngeal strains. | 2009 | Ann. Clin. Microbiol. Antimicrob. | pmid:19951439 |
| Ben Mansour K et al. | Primary resistance to clarithromycin, metronidazole and amoxicillin of Helicobacter pylori isolated from Tunisian patients with peptic ulcers and gastritis: a prospective multicentre study. | 2010 | Ann. Clin. Microbiol. Antimicrob. | pmid:20707901 |