| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Tuberculosis | D014376 | 20 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Nocardia Infections | D009617 | 6 associated lipids |
| Diarrhea | D003967 | 32 associated lipids |
| Hearing Loss, Sensorineural | D006319 | 8 associated lipids |
| Otitis Media | D010033 | 12 associated lipids |
| Carcinoma, Basal Cell | D002280 | 6 associated lipids |
| Arrhythmias, Cardiac | D001145 | 42 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Bacterial Infections | D001424 | 21 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Lupus Erythematosus, Systemic | D008180 | 43 associated lipids |
| Stomach Diseases | D013272 | 7 associated lipids |
| Lung Diseases | D008171 | 37 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Skin Neoplasms | D012878 | 12 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Leishmaniasis, Visceral | D007898 | 13 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with clarithromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Heifets L et al. | Capreomycin is active against non-replicating M. tuberculosis. | 2005 | Ann. Clin. Microbiol. Antimicrob. | pmid:15804353 |
| Sankar MM et al. | In-vitro antimycobacterial drug susceptibility testing of non-tubercular mycobacteria by tetrazolium microplate assay. | 2008 | Ann. Clin. Microbiol. Antimicrob. | pmid:18620572 |
| Destura RV et al. | Laboratory diagnosis and susceptibility profile of Helicobacter pylori infection in the Philippines. | 2004 | Ann. Clin. Microbiol. Antimicrob. | pmid:15546485 |
| Tanabe H et al. | Vonoprazan-based triple therapy is non-inferior to susceptibility-guided proton pump inhibitor-based triple therapy for Helicobacter pylori eradication. | 2018 | Ann. Clin. Microbiol. Antimicrob. | pmid:29950163 |
| Akram FE et al. | A combination of silver nanoparticles and visible blue light enhances the antibacterial efficacy of ineffective antibiotics against methicillin-resistant Staphylococcus aureus (MRSA). | 2016 | Ann. Clin. Microbiol. Antimicrob. | pmid:27530257 |
| Bago J et al. | Antimicrobial resistance of H. pylori to the outcome of 10-days vs. 7-days Moxifloxacin based therapy for the eradication: a randomized controlled trial. | 2010 | Ann. Clin. Microbiol. Antimicrob. | pmid:20398300 |
| Chen J et al. | Application of next-generation sequencing to characterize novel mutations in clarithromycin-susceptible Helicobacter pylori strains with A2143G of 23S rRNA gene. | 2018 | Ann. Clin. Microbiol. Antimicrob. | pmid:29562911 |
| Seck A et al. | Primary antibiotic resistance and associated mechanisms in Helicobacter pylori isolates from Senegalese patients. | 2013 | Ann. Clin. Microbiol. Antimicrob. | pmid:23298145 |
| Dohar J et al. | Activity of telithromycin and comparators against bacterial pathogens isolated from 1,336 patients with clinically diagnosed acute sinusitis. | 2004 | Ann. Clin. Microbiol. Antimicrob. | pmid:15287988 |
| Jones ME et al. | Emerging resistance among bacterial pathogens in the intensive care unit--a European and North American Surveillance study (2000-2002). | 2004 | Ann. Clin. Microbiol. Antimicrob. | pmid:15283864 |
| Mohan S et al. | Physician behaviour for antimicrobial prescribing for paediatric upper respiratory tract infections: a survey in general practice in Trinidad, West Indies. | 2004 | Ann. Clin. Microbiol. Antimicrob. | pmid:15196306 |
| Bolland MJ et al. | Osteomalacia in an HIV-infected man receiving rifabutin, a cytochrome P450 enzyme inducer: a case report. | 2008 | Ann. Clin. Microbiol. Antimicrob. | pmid:18226256 |
| Korkmaz S et al. | Unusual manifestations of acute Q fever: autoimmune hemolytic anemia and tubulointerstitial nephritis. | 2012 | Ann. Clin. Microbiol. Antimicrob. | pmid:22607576 |
| Valentini P et al. | An uncommon presentation for a severe invasive infection due to methicillin-resistant Staphylococcus aureus clone USA300 in Italy: a case report. | 2008 | Ann. Clin. Microbiol. Antimicrob. | pmid:18447939 |
| Myers AL et al. | Genetic commonality of macrolide-resistant group A beta hemolytic streptococcus pharyngeal strains. | 2009 | Ann. Clin. Microbiol. Antimicrob. | pmid:19951439 |
| Chen J and Raymond K | Roles of rifampicin in drug-drug interactions: underlying molecular mechanisms involving the nuclear pregnane X receptor. | 2006 | Ann. Clin. Microbiol. Antimicrob. | pmid:16480505 |
| Roberts JC et al. | Fatal necrotizing pneumonia due to a Panton-Valentine leukocidin positive community-associated methicillin-sensitive Staphylococcus aureus and Influenza co-infection: a case report. | 2008 | Ann. Clin. Microbiol. Antimicrob. | pmid:18284686 |
| Ribeiro ML et al. | Mutations in the 23S rRNA gene are associated with clarithromycin resistance in Helicobacter pylori isolates in Brazil. | 2003 | Ann. Clin. Microbiol. Antimicrob. | pmid:14633281 |
| Jenkins SG et al. | Trends in antibacterial resistance among Streptococcus pneumoniae isolated in the USA: update from PROTEKT US Years 1-4. | 2008 | Ann. Clin. Microbiol. Antimicrob. | pmid:18190701 |
| Ben Mansour K et al. | Primary resistance to clarithromycin, metronidazole and amoxicillin of Helicobacter pylori isolated from Tunisian patients with peptic ulcers and gastritis: a prospective multicentre study. | 2010 | Ann. Clin. Microbiol. Antimicrob. | pmid:20707901 |
| Anand TD et al. | Superantigen profiles of emm and emm-like typeable and nontypeable pharyngeal streptococcal isolates of South India. | 2012 | Ann. Clin. Microbiol. Antimicrob. | pmid:22296671 |
| Tsumoto C et al. | Long-term efficacy of Helicobacter pylori eradication in patients with idiopathic thrombocytopenic purpura: 7-year follow-up prospective study. | 2009 | Ann. Hematol. | pmid:19096845 |
| Soler JA et al. | H. pylori eradication does not reduce paraprotein levels in monoclonal gammopathy of unknown significance (MGUS): a prospective cohort study. | 2009 | Ann. Hematol. | pmid:19159929 |
| Kornacker M et al. | Occurrence of sarcoidosis subsequent to chemotherapy for non-Hodgkin's lymphoma: report of two cases. | 2002 | Ann. Hematol. | pmid:11907791 |
| Kato H et al. | Addition of clarithromycin to lenalidomide/low-dose dexamethasone was effective in a case of relapsed myeloma after long-term use of lenalidomide. | 2013 | Ann. Hematol. | pmid:23625297 |
| Bilgilier C et al. | Prevalence of clarithromycin-resistant Helicobacter pylori strains in gastric mucosa-associated lymphoid tissue lymphoma patients. | 2016 | Ann. Hematol. | pmid:27091350 |
| Huang HC et al. | Primary central nervous system diffuse large B cell lymphoma transformed from orbital mucosa-associated lymphoid tissue lymphoma: complete response to combined intrathecal and systemic rituximab. | 2013 | Ann. Hematol. | pmid:23242476 |
| Kim H et al. | Efficacy of Helicobacter pylori eradication for the 1st line treatment of immune thrombocytopenia patients with moderate thrombocytopenia. | 2015 | Ann. Hematol. | pmid:25501820 |
| Kobayashi T et al. | The potential role of clarithromycin addition to lenalidomide and dexamethasone therapy (BiRd) in multiple myeloma. | 2018 | Ann. Hematol. | pmid:29427183 |
| Todo K et al. | Severe Helicobacter pylori gastritis-related thrombocytopenia and iron deficiency anemia in an adolescent female. | 2016 | Ann. Hematol. | pmid:26957356 |
| Alpen B et al. | Helicobacter pylori eradication therapy in gastric high grade non Hodgkin's lymphoma (NHL). | 2001 | Ann. Hematol. | pmid:11757689 |
| Tsutsumi Y et al. | Randomized study of Helicobacter pylori eradication therapy and proton pump inhibitor monotherapy for idiopathic thrombocytopenic purpura. | 2005 | Ann. Hematol. | pmid:16078036 |
| Souto Filho JTD et al. | Long-term complete remission of primary gastric plasmacytoma following endoscopic resection. | 2017 | Ann. Hematol. | pmid:28315923 |
| Musher DM | Clarithromycin therapy for Mycobacterium avium complex bacteremia. | 1995 | Ann. Intern. Med. | pmid:7778830 |
| van der Meer JT and Danner SA | Clarithromycin therapy for Mycobacterium avium complex bacteremia. | 1995 | Ann. Intern. Med. | pmid:7778831 |
| Patel AM et al. | Statin toxicity from macrolide antibiotic coprescription: a population-based cohort study. | 2013 | Ann. Intern. Med. | pmid:23778904 |
| Shafran SD et al. | Successful discontinuation of therapy for disseminated Mycobacterium avium complex infection after effective antiretroviral therapy. | 2002 | Ann. Intern. Med. | pmid:12416943 |
| Singh N and Yu VL | Clarithromycin therapy for Mycobacterium avium complex bacteremia. | 1995 | Ann. Intern. Med. | pmid:7632282 |
| Wallace RJ et al. | Clinical trial of clarithromycin for cutaneous (disseminated) infection due to Mycobacterium chelonae. | 1993 | Ann. Intern. Med. | pmid:8357113 |
| Neu HC | New macrolide antibiotics: azithromycin and clarithromycin. | 1992 | Ann. Intern. Med. | pmid:1310839 |
| McMahon BJ et al. | The relationship among previous antimicrobial use, antimicrobial resistance, and treatment outcomes for Helicobacter pylori infections. | 2003 | Ann. Intern. Med. | pmid:13679322 |
| Sjölund M et al. | Long-term persistence of resistant Enterococcus species after antibiotics to eradicate Helicobacter pylori. | 2003 | Ann. Intern. Med. | pmid:13679325 |
| Summaries for patients. Past antibiotic use affects resistance and outcomes of Helicobacter pylori infection. | 2003 | Ann. Intern. Med. | pmid:13679344 | |
| Summaries for patients. Effects of antibiotic treatment for Helicobacter pylori on normal bowel bacteria. | 2003 | Ann. Intern. Med. | pmid:13679347 | |
| Liviu L et al. | Pancreatitis induced by clarithromycin. | 1996 | Ann. Intern. Med. | pmid:8849171 |
| Seow J and Chew FT | Risk factors for Helicobacter pylori resistance. | 2004 | Ann. Intern. Med. | pmid:15172911 |
| Jafri NS et al. | Meta-analysis: sequential therapy appears superior to standard therapy for Helicobacter pylori infection in patients naive to treatment. | 2008 | Ann. Intern. Med. | pmid:18490667 |
| Summaries for patients. Factors associated with Helicobacter pylori infections in the United States that are resistant to usual antibiotics. | 2002 | Ann. Intern. Med. | pmid:11797613 | |
| De Francesco V et al. | Clarithromycin-resistant genotypes and eradication of Helicobacter pylori. | 2006 | Ann. Intern. Med. | pmid:16418408 |
| Trivedi S et al. | Clarithromycin and digoxin toxicity. | 1998 | Ann. Intern. Med. | pmid:9518419 |