clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with clarithromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Patel AM et al. | Statin toxicity from macrolide antibiotic coprescription: a population-based cohort study. | 2013 | Ann. Intern. Med. | pmid:23778904 |
Krashias G et al. | Prevalence of Helicobacter pylori cagA and vacA genes in Cypriot patients. | 2013 | J Infect Dev Ctries | pmid:24042099 |
Nguyen L and Taylor-Gjevre RM | An emerging role for clarithromycin in adult-onset still disease? | 2013 | J Clin Rheumatol | pmid:24048102 |
Evdokimova AG et al. | [New approaches to therapy of Helicobacterpylori infection (by the materials of the Maastricht Consensus-IV, Florence, 2010)]. | 2013 | Antibiot. Khimioter. | pmid:24640139 |
Shinahara W et al. | Immunomodulator clarithromycin enhances mucosal and systemic immune responses and reduces re-infection rate in pediatric patients with influenza treated with antiviral neuraminidase inhibitors: a retrospective analysis. | 2013 | PLoS ONE | pmid:23875018 |
Friedman ND et al. | Mycobacterium ulcerans disease: experience with primary oral medical therapy in an Australian cohort. | 2013 | PLoS Negl Trop Dis | pmid:23875050 |
Zhuo FL et al. | Clinical isolates of Mycobacterium abscessus in Guangzhou area most possibly from the environmental infection showed variable susceptibility. | 2013 | Chin. Med. J. | pmid:23673103 |
Sarkeshikian SS et al. | Azithromycin based triple therapy versus standard clarithromycin based triple therapy in eradication of Helicobacter pylori infection in Iran: a randomized controlled clinical trial. | 2013 | Turk J Gastroenterol | pmid:23794338 |
Lai J et al. | Epithelioid histiocytic infiltrate caused by Mycobacterium scrofulaceum infection: a potential mimic of various neoplastic entities. | 2013 | Am J Dermatopathol | pmid:22935892 |
Boyanova L et al. | Living in Sofia is associated with a risk for antibiotic resistance in Helicobacter pylori: a Bulgarian study. | 2013 | Folia Microbiol. (Praha) | pmid:23580173 |
Bradbeer L et al. | Childhood headache and H. pylori--a possible association. | 2013 | Aust Fam Physician | pmid:23529524 |
Kim T et al. | [Clarithromycin-resistant Helicobacter pylori associated with 23S rRNA point mutations in Jeju Island]. | 2013 | Korean J Gastroenterol | pmid:23756666 |
Faraji F et al. | The effect of Helicobacter pylori eradication on migraine: a randomized, double blind, controlled trial. | 2012 Nov-Dec | Pain Physician | pmid:23159967 |
Eremenko AA et al. | [Effect of clarithromycin on the systemic inflammatory response syndrome severity in patients after myocardial revascularization surgery]. | 2012 May-Jun | Anesteziol Reanimatol | pmid:22993930 |
Singh V et al. | Vesicular palmoplantar pityriasis rosea. | 2012 Mar-Apr | Skinmed | pmid:22545332 |
Gutiérrez-Castrellón P et al. | Efficacy and safety of clarithromycin in pediatric patients with upper respiratory infections: a systematic review with meta-analysis. | 2012 Mar-Apr | Rev. Invest. Clin. | pmid:22991774 |
Rajendiran S et al. | Increased protein carbonylation and decreased antioxidant status in anemic H. pylori infected patients: effect of treatment. | 2012 Jul-Aug | Saudi J Gastroenterol | pmid:22824768 |
De Sanctis V et al. | Anti-Helicobacter pylori therapy in primary MALT lymphoma of rectum. | 2012 Jul-Aug | Tumori | pmid:23052174 |
Figueroa M et al. | [Antimicrobial susceptibility of Helicobacter pylori with chronic gastritis]. | 2012 Jan-Mar | Biomedica | pmid:23235785 |
de Lalibera IB et al. | Meningoencephalitis associated with Mycoplasma pneumoniae. | 2012 Jan-Mar | Einstein (Sao Paulo) | pmid:23045836 |
Dhillon GS et al. | Clarithromycin for prevention of bronchiolitis obliterans syndrome in lung allograft recipients. | 2012 Jan-Feb | Clin Transplant | pmid:21352378 |
Onsun N et al. | Impact of Helicobacter pylori infection on severity of psoriasis and response to treatment. | 2012 Jan-Feb | Eur J Dermatol | pmid:22063790 |
Montero-Tinnirello J et al. | [Pulmonary hemorrhage due to leptospirosis]. | 2012 Jan-Feb | Med Intensiva | pmid:21592620 |
Dai WQ et al. | The eradicating Helicobacter pylori infection in duodenal ulcer patients by three short-term triple therapies in China: a multicenter clinical comparative study. | 2012 Jan-Feb | Hepatogastroenterology | pmid:22260837 |
Yakoob J et al. | Prevalence of non Helicobacter pylori species in patients presenting with dyspepsia. | 2012 | BMC Gastroenterol | pmid:22226326 |
Raj JM and Raj SM | Concern about the efficacy of clarithromycin containing standard triple therapy in the eradication of Helicobacter pylori infection in Malaysia. | 2012 | Med. J. Malaysia | pmid:23770883 |
Ohtani M et al. | Amino acid and vitamin supplementation improved health conditions in elderly participants. | 2012 | J Clin Biochem Nutr | pmid:22448099 |
[Experience with treatment of chronic polypoid rhinosinusitis using low doses of clarithromycin in the postoperative period]. | 2012 | Vestn. Otorinolaringol. | pmid:22678641 | |
Kim SY et al. | Effectiveness of three times daily lansoprazole/amoxicillin dual therapy for Helicobacter pylori infection in Korea. | 2012 | Br J Clin Pharmacol | pmid:21689141 |
Lotfy HM and Abdel-Monem Hagazy M | Comparative study of novel spectrophotometric methods manipulating ratio spectra: an application on pharmaceutical ternary mixture of omeprazole, tinidazole and clarithromycin. | 2012 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:22683662 |
Rajper S et al. | Macrolide and fluoroquinolone resistance in Helicobacter pylori isolates: an experience at a tertiary care centre in Pakistan. | 2012 | J Pak Med Assoc | pmid:23866399 |
Goswami S et al. | Anti-Helicobacter pylori potential of artemisinin and its derivatives. | 2012 | Antimicrob. Agents Chemother. | pmid:22687518 |
Cuadrado-LavÃn A et al. | Levofloxacin versus clarithromycin in a 10 day triple therapy regimen for first-line Helicobacter pylori eradication: a single-blind randomized clinical trial. | 2012 | J. Antimicrob. Chemother. | pmid:22687889 |
Perez AP et al. | Increased brain radioactivity by intranasal P-labeled siRNA dendriplexes within in situ-forming mucoadhesive gels. | 2012 | Int J Nanomedicine | pmid:22457595 |
González-MartÃnez R et al. | Antibiotic prescription in the treatment of odontogenic infection by health professionals: a factor to consensus. | 2012 | Med Oral Patol Oral Cir Bucal | pmid:22143715 |
Gisbert JP and Calvet X | Review article: rifabutin in the treatment of refractory Helicobacter pylori infection. | 2012 | Aliment. Pharmacol. Ther. | pmid:22129228 |
Bobacheva TIu | [The treatment of chronic polypous rhinosinusitis in the postoperative period with low doses of clarithromycin]. | 2012 | Vestn. Otorinolaringol. | pmid:23011378 |
Omoruyi OJ et al. | Metachronous Mycobacterium terrae complex tenosynovitis of the hand. | 2012 | J Hand Surg Eur Vol | pmid:22415428 |
Ohe M and Hashino S | Successful treatment of eosinophilic gastroenteritis with clarithromycin. | 2012 | Korean J. Intern. Med. | pmid:23269887 |
Breda R et al. | [Mycobacterium massiliense bone infection]. | 2012 | Med Mal Infect | pmid:22154522 |
Takahashi E et al. | Oral clarithromycin enhances airway immunoglobulin A (IgA) immunity through induction of IgA class switching recombination and B-cell-activating factor of the tumor necrosis factor family molecule on mucosal dendritic cells in mice infected with influenza A virus. | 2012 | J. Virol. | pmid:22896605 |
Greenstein RJ et al. | Vitamins A & D inhibit the growth of mycobacteria in radiometric culture. | 2012 | PLoS ONE | pmid:22235314 |
Chung JW et al. | Ten-day sequential versus triple therapy for Helicobacter pylori eradication: a prospective, open-label, randomized trial. | 2012 | J. Gastroenterol. Hepatol. | pmid:22849546 |
Chan A et al. | A case of wrist tenosynovitis caused by Mycobacterium kansasii in a renal transplant recipient. | 2012 | Transpl Infect Dis | pmid:22822725 |
Deguchi R et al. | Effect of pretreatment with Lactobacillus gasseri OLL2716 on first-line Helicobacter pylori eradication therapy. | 2012 | J. Gastroenterol. Hepatol. | pmid:22098133 |
Gao M et al. | The effects of transrectal radiofrequency hyperthermia on patients with chronic prostatitis and the changes of MDA, NO, SOD, and Zn levels in pretreatment and posttreatment. | 2012 | Urology | pmid:22100490 |
Zullo A et al. | Role of gastritis pattern on Helicobacter pylori eradication. | 2012 | Intern Emerg Med | pmid:22105372 |
von Müller L et al. | [Current data and trends on the development of antibiotic resistance of Clostridium difficile]. | 2012 | Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz | pmid:23114440 |
Davies BS et al. | Non-tuberculous slow-growing mycobacterial pulmonary infections in non-HIV-infected patients in south London. | 2012 | Scand. J. Infect. Dis. | pmid:23078529 |
Madi D et al. | Successful treatment of cerebral toxoplasmosis with clindamycin: a case report. | 2012 | Oman Med J | pmid:23074553 |
Qian J et al. | Levofloxacin-containing triple and sequential therapy or standard sequential therapy as the first line treatment for Helicobacter pylori eradication in China. | 2012 | Helicobacter | pmid:23067317 |
Liang J et al. | Helicobacter pylori eradication with ecabet sodium, omeprazole, amoxicillin, and clarithromycin versus bismuth, omeprazole, amoxicillin, and clarithromycin quadruple therapy: a randomized, open-label, phase IV trial. | 2012 | Helicobacter | pmid:23066868 |
Espinal DA et al. | [Human metapneumovirus in children: first cases in Colombia]. | 2012 | Biomedica | pmid:23242289 |
Tsay FW et al. | Sequential therapy achieves a higher eradication rate than standard triple therapy in Taiwan. | 2012 | J. Gastroenterol. Hepatol. | pmid:21871025 |
Cao S et al. | Pharmacokinetic interactions between ilaprazole and clarithromycin following ilaprazole, clarithromycin and amoxicillin triple therapy. | 2012 | Acta Pharmacol. Sin. | pmid:22820908 |
Saito R et al. | Molecular mechanism of macrolide-lincosamide resistance in Moraxella catarrhalis. | 2012 | J. Med. Microbiol. | pmid:22820696 |
Flamm RK et al. | Macrolide and tetracycline resistance among Moraxella catarrhalis isolates from 2009 to 2011. | 2012 | Diagn. Microbiol. Infect. Dis. | pmid:22819241 |
Kuo CH et al. | The Optimal First-Line Therapy of Helicobacter pylori Infection in Year 2012. | 2012 | Gastroenterol Res Pract | pmid:22792095 |
Marzouk H et al. | The utility of nasopharyngeal culture in the management of chronic adenoiditis. | 2012 | Int. J. Pediatr. Otorhinolaryngol. | pmid:22784508 |
Hu FL et al. | [Jinghuaweikang capsules combined with triple therapy in the treatment of Helicobacter pylori associated gastritis and duodenal ulcer and analysis of antibiotic resistance: a multicenter, randomized, controlled, clinical study]. | 2012 | Zhonghua Yi Xue Za Zhi | pmid:22781295 |
Sakinc T et al. | Influence of a 23S ribosomal RNA mutation in Helicobacter pylori strains on the in vitro synergistic effect of clarithromycin and amoxicillin. | 2012 | BMC Res Notes | pmid:23110798 |
Lange JN et al. | Sensitivity of human strains of Oxalobacter formigenes to commonly prescribed antibiotics. | 2012 | Urology | pmid:22656407 |
Robinson P et al. | Clarithromycin therapy for patients with cystic fibrosis: a randomized controlled trial. | 2012 | Pediatr. Pulmonol. | pmid:22266895 |
Blumenthal A et al. | M. tuberculosis induces potent activation of IDO-1, but this is not essential for the immunological control of infection. | 2012 | PLoS ONE | pmid:22649518 |
Korownyk C and Kolber MR | Is quadruple therapy the new triple therapy for H pylori? | 2012 | Can Fam Physician | pmid:22267623 |
Huang J et al. | [A 10-day sequential therapy for eradication of Helicobacter pylori infection in children]. | 2012 | Zhonghua Er Ke Za Zhi | pmid:23158730 |
Sugimoto M and Furuta T | Efficacy of esomeprazole in treating acid-related diseases in Japanese populations. | 2012 | Clin Exp Gastroenterol | pmid:22649281 |
Mumoli N and Cei M | Clinical images: community-acquired pneumonia. | 2012 | CMAJ | pmid:22271912 |
Henneman A and Thornby KA | Risk of hypotension with concomitant use of calcium-channel blockers and macrolide antibiotics. | 2012 | Am J Health Syst Pharm | pmid:22644980 |
English ML et al. | Cethromycin versus clarithromycin for community-acquired pneumonia: comparative efficacy and safety outcomes from two double-blinded, randomized, parallel-group, multicenter, multinational noninferiority studies. | 2012 | Antimicrob. Agents Chemother. | pmid:22290969 |
Tatar EÇ et al. | Prevalence of biofilms and their response to medical treatment in chronic rhinosinusitis without polyps. | 2012 | Otolaryngol Head Neck Surg | pmid:22241786 |
Birteksöz-Tan AS and Zeybek Z | Postantibiotic effect of various antibiotics on Legionella pneumophila strains isolated from water systems. | 2012 | Folia Microbiol. (Praha) | pmid:22627604 |
Chang WJ et al. | Successful salvage treatment of steroid-refractory bronchiolar COP with low-dose macrolides. | 2012 | Pathol. Int. | pmid:22243785 |
Chhabra N et al. | Pharmacotherapy for multidrug resistant tuberculosis. | 2012 | J Pharmacol Pharmacother | pmid:22629081 |
Prasad R | Multidrug and extensively drug-resistant tuberculosis management: Evidences and controversies. | 2012 | Lung India | pmid:22628931 |
Zhou YQ et al. | Modified Sequential Therapy Regimen versus Conventional Triple Therapy for Helicobacter Pylori Eradication in Duodenal Ulcer Patients in China: A Multicenter Clinical Comparative Study. | 2012 | Gastroenterol Res Pract | pmid:22550478 |
Kamijo F et al. | A Case of Mycobacterial Skin Disease Caused by Mycobacterium peregrinum, and a Review of Cutaneous Infection. | 2012 | Case Rep Dermatol | pmid:22548041 |
Goodman JJ and Martin SI | Critical appraisal of ceftaroline in the management of community-acquired bacterial pneumonia and skin infections. | 2012 | Ther Clin Risk Manag | pmid:22547933 |
Werth S et al. | Efficacy and safety of venous thromboembolism prophylaxis with apixaban in major orthopedic surgery. | 2012 | Ther Clin Risk Manag | pmid:22547932 |
Sereni G et al. | Efficacy of a therapeutic strategy for eradication of Helicobacter pylori infection. | 2012 | World J. Gastroenterol. | pmid:22969227 |
Bajaj P et al. | Locally delivered 0.5% clarithromycin, as an adjunct to nonsurgical treatment in chronic periodontitis with well-controlled type 2 diabetes: a randomized controlled clinical trial. | 2012 | J Investig Clin Dent | pmid:22976782 |
Akelma AZ et al. | Clarithromycin in treatment of acute asthma exacerbations: principles of appropriate antibiotic use. | 2012 | Pediatr Allergy Immunol | pmid:22984834 |
Karlgren M et al. | Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. | 2012 | J. Med. Chem. | pmid:22541068 |
Monno R et al. | Helicobacter pylori clarithromycin resistance detected by Etest and TaqMan real-time polymerase chain reaction: a comparative study. | 2012 | APMIS | pmid:22882260 |
Pandya GJ et al. | Unilateral lobar pulmonary edema. | 2012 | J Assoc Physicians India | pmid:23547417 |
Khan GA et al. | The development and application of a system for simultaneously determining anti-infectives and nasal decongestants using on-line solid-phase extraction and liquid chromatography-tandem mass spectrometry. | 2012 | J Pharm Biomed Anal | pmid:22459504 |
Adrjanowicz K et al. | Molecular dynamics in supercooled liquid and glassy states of antibiotics: azithromycin, clarithromycin and roxithromycin studied by dielectric spectroscopy. Advantages given by the amorphous state. | 2012 | Mol. Pharm. | pmid:22540343 |
Gisbert JP and Calvet X | Update on non-bismuth quadruple (concomitant) therapy for eradication of Helicobacter pylori. | 2012 | Clin Exp Gastroenterol | pmid:22457599 |
Hahn DL et al. | Chlamydia pneumoniae-specific IgE is prevalent in asthma and is associated with disease severity. | 2012 | PLoS ONE | pmid:22545149 |
Wang H et al. | [Antimicrobial susceptibility of community-acquired respiratory tract pathogens isolated from adults in China during 2009 and 2010]. | 2012 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:22455967 |
Zautner AE | Adenotonsillar disease. | 2012 | Recent Pat Inflamm Allergy Drug Discov | pmid:22452646 |
Cronnolly B and Pegrum H | Fentanyl-clarithromycin interaction. | 2012 | BMJ Case Rep | pmid:22778456 |
Maselli DJ et al. | Clinical evaluation of the role of ceftaroline in the management of community acquired bacterial pneumonia. | 2012 | Infect Drug Resist | pmid:22355258 |
Berti AD et al. | Altering the proclivity towards daptomycin resistance in methicillin-resistant Staphylococcus aureus using combinations with other antibiotics. | 2012 | Antimicrob. Agents Chemother. | pmid:22802248 |
Iino R et al. | A microfluidic device for simple and rapid evaluation of multidrug efflux pump inhibitors. | 2012 | Front Microbiol | pmid:22347225 |
Khavinson VKh et al. | Peptidergic regulation of expression of genes encoding antioxidant and anti-inflammatory proteins. | 2012 | Bull. Exp. Biol. Med. | pmid:22803148 |
Dholakia Y et al. | Drug-resistant tuberculosis: Study of clinical practices of chest physicians, Maharashtra, India. | 2012 | Lung India | pmid:22345911 |
Lachter J et al. | Yellow brain culinary-medicinal mushroom, Tremella mesenterica Ritz.:Fr. (higher Basidiomycetes), is subjectively but not objectively effective for eradication of Helicobacter pylori: a prospective controlled trial. | 2012 | Int J Med Mushrooms | pmid:22339708 |
Molina-Infante J et al. | Nonbismuth quadruple (concomitant) therapy: empirical and tailored efficacy versus standard triple therapy for clarithromycin-susceptible Helicobacter pylori and versus sequential therapy for clarithromycin-resistant strains. | 2012 | Helicobacter | pmid:22759326 |
Song JY et al. | Case series of mycobacterium abscessus infections associated with a trigger point injection and epidural block at a rural clinic. | 2012 | Epidemiol Health | pmid:22323979 |