clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
|---|
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
|---|
What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with clarithromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (2)
- Clin. Infect. Dis. (1)
- FEMS Immunol. Med. Microbiol. (1)
- Others (2)
| Model | Cross reference | Weighted score | Related literatures |
|---|
NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Fock KM et al. | A randomised trial of amoxycillin versus clarithromycin in combination with omeprazole for eradication of Helicobacter pylori infection in Singapore. | 2000 | Singapore Med J | pmid:11281438 |
| Mak SK et al. | A retrospective study on efficacy of proton-pump inhibitor-based triple therapy for eradication of Helicobacter pylori in patients with chronic renal failure. | 2003 | Singapore Med J | pmid:14503780 |
| Singh V et al. | Vesicular palmoplantar pityriasis rosea. | 2012 Mar-Apr | Skinmed | pmid:22545332 |
| Bernstein JM and Bacheller CD | It's on the tip of my tongue. | Skinmed | pmid:16687984 | |
| Alberts JH and Boyd AS | Nocardia otitidiscaviarum: an unusual Nocardia species causing a primary lymphocutaneous infectious process in a mildly immunosuppressed patient. | 2002 Sep-Oct | Skinmed | pmid:14673241 |
| Waites K et al. | In vitro activities of oral antimicrobial agents against penicillin-resistant Streptococcus pneumoniae: implications for outpatient treatment. | 1997 | South. Med. J. | pmid:9191739 |
| Krishna M and Lalmuanpuii J | Helicobacter pylori treatment. | 2005 | South. Med. J. | pmid:16351026 |
| Gurbuz AK et al. | Effect of N-acetyl cysteine on Helicobacter pylori. | 2005 | South. Med. J. | pmid:16351030 |
| Kanbay M et al. | Hyponatremia due to an additive effect of carbamazepine and clarithromycin. | 2007 | South. Med. J. | pmid:17330699 |
| Ermis F et al. | Second-line levofloxacin-based triple therapy's efficiency for Helicobacter pylori eradication in patients with peptic ulcer. | 2011 | South. Med. J. | pmid:21886067 |
| Bégué RE et al. | Effect of Helicobacter pylori eradication in the glycemia of children with type 1 diabetes: a preliminary study. | 2002 | South. Med. J. | pmid:12190218 |
| Nadir I et al. | Comparison of two different treatment protocols in Helicobacter pylori eradication. | 2011 | South. Med. J. | pmid:21206418 |
| Knower MT et al. | Clarithromycin for safe and cost-effective reduction of cyclosporine doses in lung allograft recipients. | 2000 | South. Med. J. | pmid:11095559 |
| Asnis DS et al. | Mycobacterium avium-intracellulare complex pneumonia in a non-HIV-infected individual: an increasingly recognized disease. | 1996 | South. Med. J. | pmid:8638183 |
| Demir M et al. | Clarithromycin resistance and efficacy of clarithromycin-containing triple eradication therapy for Helicobacter pylori infection in type 2 diabetes mellitus patients. | 2009 | South. Med. J. | pmid:19864973 |
| Cheng VC et al. | Two probable cases of serious drug interaction between clarithromycin and colchicine. | 2005 | South. Med. J. | pmid:16144178 |
| Randhawa K et al. | Nine-year progression of untreated pulmonary Mycobacterium szulgai infection. | 2010 | South. Med. J. | pmid:20622732 |
| Sadeghifard N et al. | Survey in Iran of clarithromycin resistance in Helicobacter pylori isolates by PCR-RFLP. | 2013 | Southeast Asian J. Trop. Med. Public Health | pmid:23682442 |
| Kumala W and Rani A | Patterns of Helicobacter pylori isolate resistance to fluoroquinolones, amoxicillin, clarithromycin and metronidazoles. | 2006 | Southeast Asian J. Trop. Med. Public Health | pmid:17333742 |
| Iamsawat S et al. | Multiplex PCR for detection of clarithromycin resistance and simultaneous species identification of Mycobacterium avium complex. | 2010 | Southeast Asian J. Trop. Med. Public Health | pmid:20578547 |
| Lotfy HM and Abdel-Monem Hagazy M | Comparative study of novel spectrophotometric methods manipulating ratio spectra: an application on pharmaceutical ternary mixture of omeprazole, tinidazole and clarithromycin. | 2012 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:22683662 |
| Ahmed S and Atia NN | Simultaneous determination of triple therapy for Helicobacter pylori in human plasma by reversed phase chromatography with online wavelength switching. | 2015 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:25459696 |
| Earl AM et al. | High quality draft genome sequence of Segniliparus rugosus CDC 945(T)= (ATCC BAA-974(T)). | 2011 | Stand Genomic Sci | pmid:22675588 |
| Sikorski J et al. | Complete genome sequence of Segniliparus rotundus type strain (CDC 1076). | 2010 | Stand Genomic Sci | pmid:21304703 |
| Lee HY et al. | Survey of methadone-drug interactions among patients of methadone maintenance treatment program in Taiwan. | 2012 | Subst Abuse Treat Prev Policy | pmid:22429858 |
| Nzeako BC and Al-Namaani F | The antibacterial activity of honey on helicobacter pylori. | 2006 | Sultan Qaboos Univ Med J | pmid:21748138 |
| Cone LA et al. | Delirium in the elderly resulting from azithromycin therapy. | 2003 | Surg Neurol | pmid:12826358 |
| Schulzke S et al. | Mycobacterium bohemicum--a cause of paediatric cervical lymphadenitis. | 2004 | Swiss Med Wkly | pmid:15190440 |
| Piso RJ et al. | Coverage of atypical pathogens for hospitalised patients with community-acquired pneumonia is not guided by clinical parameters. | 2013 | Swiss Med Wkly | pmid:24089030 |
| Wang B et al. | In-vitro characterisation of a novel antimicrobial agent, TNP-2092, against Helicobacter pylori clinical isolates. | Swiss Med Wkly | pmid:30044468 | |
| Soltermann A et al. | Assessment of Helicobacter pylori clarithromycin resistance mutations in archival gastric biopsy samples. | 2005 | Swiss Med Wkly | pmid:16034687 |
| Moayyedi P and Murphy B | Helicobacter pylori: a clinical update. | 2001 | Symp Ser Soc Appl Microbiol | pmid:11422568 |
| Kusters JG and Kuipers EJ | Antibiotic resistance of Helicobacter pylori. | 2001 | Symp Ser Soc Appl Microbiol | pmid:11422569 |
| Choi SJ et al. | Column-switching high-performance liquid chromatographic determination of clarithromycin in human plasma with electrochemical detection. | 2001 | Talanta | pmid:18968261 |
| Li W et al. | Determination of clarithromycin in rat plasma by HPLC-UV method with pre-column derivatization. | 2007 | Talanta | pmid:19071316 |
| Vu DH et al. | Simultaneous determination of rifampicin, clarithromycin and their metabolites in dried blood spots using LC-MS/MS. | 2014 | Talanta | pmid:24607103 |
| Minushkin ON et al. | [Age and eradication treatment of duodenal ulcer]. | 2007 | Ter. Arkh. | pmid:17460963 |
| Vasil'ev IuV et al. | [Fromilid (clarithromycin) in eradication patients in patients with duodenal ulcer associated with Helicobacter pylori (comparison of two treatment variations)]. | 2002 | Ter. Arkh. | pmid:12360599 |
| Maev IV et al. | [Eradication therapy for Helicobacter pylori infection: review of world trends]. | 2014 | Ter. Arkh. | pmid:24779078 |
| Tsukanov VV et al. | [Helicobacter pylori eradication: current status]. | 2013 | Ter. Arkh. | pmid:23653944 |
| Maev IV et al. | [Experience in the use of losek (omeprazole) in gastroenterology]. | 2001 | Ter. Arkh. | pmid:11523419 |
| Konorev MR | [Use of the immunopotentiator N-acetyl-glucosamine-N-acetylmuramyl dipeptide during triple anti-Helicobacter pylori therapy]. | 2012 | Ter. Arkh. | pmid:23479993 |
| Kirika NV et al. | [Efficacy of different schemes of anti-helicobacter therapy in duodenal ulcer]. | 2004 | Ter. Arkh. | pmid:15106408 |
| Isakov VA et al. | [Results of an open multicenter study of the efficiency of one-week anti-helicobacter therapy using omeprazole, clarithromycin, and amoxicillin in patients with duodenal peptic ulcer]. | 2003 | Ter. Arkh. | pmid:14708448 |
| Coeman M et al. | Neomacrolides in the treatment of patients with severe asthma and/or bronchiectasis: a retrospective observational study. | 2011 | Ther Adv Respir Dis | pmid:21890536 |
| Nawarskas JJ and Snowden SS | Critical appraisal of ticagrelor in the management of acute coronary syndrome. | 2011 | Ther Clin Risk Manag | pmid:22241944 |
| Rafii F et al. | Effects of treatment with antimicrobial agents on the human colonic microflora. | 2008 | Ther Clin Risk Manag | pmid:19337440 |
| Pace F et al. | A review of rabeprazole in the treatment of acid-related diseases. | 2007 | Ther Clin Risk Manag | pmid:18488081 |
| Goodman JJ and Martin SI | Critical appraisal of ceftaroline in the management of community-acquired bacterial pneumonia and skin infections. | 2012 | Ther Clin Risk Manag | pmid:22547933 |
| Werth S et al. | Efficacy and safety of venous thromboembolism prophylaxis with apixaban in major orthopedic surgery. | 2012 | Ther Clin Risk Manag | pmid:22547932 |