clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with clarithromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
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| Katayama M et al. | Preliminary study of effects of multiple oral dosing of clarithromycin on the pharmacokinetics of cyclosporine in dogs. | 2014 | J. Vet. Med. Sci. | pmid:24189617 |
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| Seung KJ et al. | Salvage therapy for multidrug-resistant tuberculosis. | 2014 | Clin. Microbiol. Infect. | pmid:23991934 |
| Kathariya R et al. | Evaluation of subgingivally delivered 0.5% clarithromycin as an adjunct to nonsurgical mechanotherapy in the management of chronic periodontitis: a short-term double blinded randomized control trial. | 2014 | J Investig Clin Dent | pmid:23097216 |
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| Bjerre M et al. | Osteoprotegerin independently predicts mortality in patients with stable coronary artery disease: the CLARICOR trial. | 2014 | Scand. J. Clin. Lab. Invest. | pmid:25026506 |
| Noh TK et al. | Infection with Mycobacterium fortuitum during acupoint embedding therapy. | 2014 | J. Am. Acad. Dermatol. | pmid:24831334 |
| Loreto ES et al. | New insights into the in vitro susceptibility of Pythium insidiosum. | 2014 | Antimicrob. Agents Chemother. | pmid:25223997 |
| Altman E et al. | Lipopolysaccharide glycotyping of clarithromycin-resistant and clarithromycin-susceptible Canadian isolates of Helicobacter pylori. | 2014 | Can. J. Microbiol. | pmid:24392924 |
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| Yamada K et al. | Azithromycin inhibits MUC5AC induction via multidrug-resistant Acinetobacter baumannii in human airway epithelial cells. | 2014 | Pulm Pharmacol Ther | pmid:24910464 |
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| Veraldi S et al. | Treatment of sporotrichoid fish tank granuloma with pulsed clarithromycin. | 2014 | Dermatology (Basel) | pmid:25228273 |
| Phillips RO et al. | Reply to "compliance with antimicrobial therapy for buruli ulcer". | 2014 | Antimicrob. Agents Chemother. | pmid:25225343 |
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| Patel SK et al. | Helicobacter pylori is not eradicated after triple therapy: a nested PCR based study. | 2014 | Biomed Res Int | pmid:25054141 |
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| Ohe M and Bohgaki T | Successful treatment with clarithromycin for patients with polymyalgia rheumatica. | 2014 | Korean J. Intern. Med. | pmid:25045305 |
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| Dalbøge CS et al. | Pharmacokinetic variability of clarithromycin and differences in CYP3A4 activity in patients with cystic fibrosis. | 2014 | J. Cyst. Fibros. | pmid:24035278 |
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| Glatz M and Muellegger RR | Drug-associated aquagenic wrinkling of the palms in an atopic male patient. | 2014 | BMJ Case Rep | pmid:24903725 |
| DiCicco M et al. | In vitro synergism of fosfomycin and clarithromycin antimicrobials against methicillin-resistant Staphylococcus pseudintermedius. | 2014 | BMC Microbiol. | pmid:24886369 |
| Noonan KA et al. | Targeting immune suppression with PDE5 inhibition in end-stage multiple myeloma. | 2014 | Cancer Immunol Res | pmid:24878583 |
| Gong EJ et al. | Meta-analysis of first-line triple therapy for helicobacter pylori eradication in Korea: is it time to change? | 2014 | J. Korean Med. Sci. | pmid:24851029 |
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| Graham DY et al. | Rational Helicobacter pylori therapy: evidence-based medicine rather than medicine-based evidence. | 2014 | Clin. Gastroenterol. Hepatol. | pmid:23751282 |
| Varvyanskaya A and Lopatin A | Efficacy of long-term low-dose macrolide therapy in preventing early recurrence of nasal polyps after endoscopic sinus surgery. | 2014 | Int Forum Allergy Rhinol | pmid:24659566 |
| Lee SH et al. | Detection and assessment of clarithromycin inducible resistant strains among Korean Mycobacterium abscessus clinical strains: PCR methods. | 2014 | J. Clin. Lab. Anal. | pmid:24652818 |
| Binh TT et al. | Discovery of novel mutations for clarithromycin resistance in Helicobacter pylori by using next-generation sequencing. | 2014 | J. Antimicrob. Chemother. | pmid:24648504 |
| Tursi A et al. | Decreasing efficacy of the standard seven-day triple therapy containing amoxycillin and clarithromycin in curing Helicobacter pylori infection in clinical setting in Italy: a 10-year follow-up study. | 2014 | Panminerva Med | pmid:24637473 |
| Wei Z et al. | Rome III criteria cannot distinguish patients with chronic gastritis from those functional dyspepsia patients. | 2014 | Helicobacter | pmid:24617669 |
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| Skvarc M et al. | Multi locus sequence typing (MLST) used as a tool to confirm the ability of susceptible Helicobacter pylori strains to gain resistance to clarithromycin during eradication therapy. | 2014 Jan-Feb | Hepatogastroenterology | pmid:24895826 |
| UÄŸurlu T et al. | Optimization and evaluation of clarithromycin floating tablets using experimental mixture design. | 2014 Mar-Apr | Acta Pol Pharm | pmid:25272652 |
| Picoli SU et al. | Resistance to amoxicillin, clarithromycin and ciprofloxacin of Helicobacter pylori isolated from Southern Brazil patients. | 2014 May-Jun | Rev. Inst. Med. Trop. Sao Paulo | pmid:24878996 |
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| Graham DY and Gisbert JP | Letter: clarithromycin dose for H. pylori therapy remains unresolved. | 2015 | Aliment. Pharmacol. Ther. | pmid:26238583 |
| Navarro-Jarabo JM et al. | Prevalence of Primary Resistance of Helicobacter pylori to Clarithromycin and Levofloxacin in Southern Spain. | 2015 | Digestion | pmid:26227669 |
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| Yu T et al. | Study on clarithromycin lactobionate based dual selector systems for the enantioseparation of basic drugs in capillary electrophoresis. | 2015 | J Sep Sci | pmid:26097042 |
| Trotti LM et al. | Clarithromycin in γ-aminobutyric acid-Related hypersomnolence: A randomized, crossover trial. | 2015 | Ann. Neurol. | pmid:26094838 |
| Tai WC et al. | Seven-Day Nonbismuth Containing Quadruple Therapy Could Achieve a Grade "A" Success Rate for First-Line Helicobacter pylori Eradication. | 2015 | Biomed Res Int | pmid:26090428 |
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| Lam A et al. | Itraconazole and clarithromycin inhibit P-glycoprotein activity in primary human sinonasal epithelial cells. | 2015 | Int Forum Allergy Rhinol | pmid:25907295 |
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| Aoki H et al. | Clarithromycin highly-loaded gastro-floating fine granules prepared by high-shear melt granulation can enhance the efficacy of Helicobacter pylori eradication. | 2015 | Eur J Pharm Biopharm | pmid:25703356 |
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| Li DQ et al. | Risk of adverse events among older adults following co-prescription of clarithromycin and statins not metabolized by cytochrome P450 3A4. | 2015 | CMAJ | pmid:25534598 |
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| Park JB et al. | Modulation of microenvironmental pH and utilization of alkalizers in crystalline solid dispersion for enhanced solubility and stability of clarithromicin. | 2015 | Arch. Pharm. Res. | pmid:25213008 |
| Anton E et al. | Randomized Trial of Clarithromycin for Mediterranean Spotted Fever. | 2015 | Antimicrob. Agents Chemother. | pmid:26711765 |
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| John A et al. | Does emerging Clarithromycin resistance signal an obituary to empirical standard triple therapy for Helicobacter pylori infection? | 2015 | Indian J Gastroenterol | pmid:26541342 |
| Mel-Hennawi D and Ahmed MR | Outcome evaluation of clarithromycin, metronidazole and lansoprazole regimens in Helicobacter pylori positive or negative children with resistant otitis media with effusion. | 2015 | J Laryngol Otol | pmid:26521817 |
| Parra D et al. | In vitro efficacy of daptomycin and teicoplanin combined with ethanol, clarithromycin or gentamicin as catheter lock solutions. | 2015 | BMC Microbiol. | pmid:26518881 |
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| Bérard A et al. | Use of macrolides during pregnancy and the risk of birth defects: a population-based study. | 2015 | Pharmacoepidemiol Drug Saf | pmid:26513406 |
| Weiss S et al. | Efficacy of Single and Combined Antibiotic Treatments of Anthrax in Rabbits. | 2015 | Antimicrob. Agents Chemother. | pmid:26392505 |
| Agrawal V et al. | A Case of Hypotension and Bradycardia Precipitated by Drug Interaction of Clarithromycin and Calcium-Channel Blocker. | 2015 | J Am Geriatr Soc | pmid:26389998 |
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| Glocker EO | The Need for Resistance Surveillance and Antimicrobial Susceptibility Testing of Helicobacter pylori. | 2015 | Digestion | pmid:26372776 |
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