clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with clarithromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (2)
- J. Antimicrob. Chemother. (1)
- Clin. Diagn. Lab. Immunol. (1)
- Others (2)
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Katelaris PH et al. | Randomized trial of omeprazole and metronidazole with amoxycillin or clarithromycin for Helicobacter pylori eradication, in a region of high primary metronidazole resistance: the HERO study. | 2000 | Aliment. Pharmacol. Ther. | pmid:10848659 |
| Ammon S et al. | Influence of age on the steady state disposition of drugs commonly used for the eradication of Helicobacter pylori. | 2000 | Aliment. Pharmacol. Ther. | pmid:10848660 |
| Molina-Infante J et al. | Clinical trial: clarithromycin vs. levofloxacin in first-line triple and sequential regimens for Helicobacter pylori eradication. | 2010 | Aliment. Pharmacol. Ther. | pmid:20180787 |
| Gisbert JP et al. | 7-day rescue therapy with ranitidine bismuth citrate after Helicobacter pylori treatment failure. | 2005 | Aliment. Pharmacol. Ther. | pmid:15882246 |
| Nista EC et al. | Moxifloxacin-based strategies for first-line treatment of Helicobacter pylori infection. | 2005 | Aliment. Pharmacol. Ther. | pmid:15882245 |
| Boixeda D et al. | Efficacy of quadruple therapy with pantoprazole, bismuth, tetracycline and metronidazole as rescue treatment for Helicobacter pylori infection. | 2002 | Aliment. Pharmacol. Ther. | pmid:12182745 |
| Lehmann FS et al. | Effect of ornidazole and clarithromycin resistance on eradication of Helicobacter pylori in peptic ulcer disease. | 2000 | Aliment. Pharmacol. Ther. | pmid:10735923 |
| Malfertheiner P et al. | Helicobacter pylori eradication is beneficial in the treatment of functional dyspepsia. | 2003 | Aliment. Pharmacol. Ther. | pmid:12969088 |
| Labenz J et al. | One-week low-dose triple therapy for Helicobacter pylori is sufficient for relief from symptoms and healing of duodenal ulcers. | 1997 | Aliment. Pharmacol. Ther. | pmid:9042978 |
| Labenz J et al. | Efficacy and tolerability of a one-week triple therapy consisting of pantoprazole, clarithromycin and amoxycillin for cure of Helicobacter pylori infection in patients with duodenal ulcer. | 1997 | Aliment. Pharmacol. Ther. | pmid:9042979 |
| Huang J and Hunt RH | The importance of clarithromycin dose in the management of Helicobacter pylori infection: a meta-analysis of triple therapies with a proton pump inhibitor, clarithromycin and amoxycillin or metronidazole. | 1999 | Aliment. Pharmacol. Ther. | pmid:10383500 |
| Miwa H et al. | Impact of rabeprazole, a new proton pump inhibitor, in triple therapy for Helicobacter pylori infection-comparison with omeprazole and lansoprazole. | 1999 | Aliment. Pharmacol. Ther. | pmid:10383502 |
| Wong BC et al. | Rabeprazole-based 3-day and 7-day triple therapy vs. omeprazole-based 7-day triple therapy for the treatment of Helicobacter pylori infection. | 2001 | Aliment. Pharmacol. Ther. | pmid:11736727 |
| Koivisto TT et al. | Primary Helicobacter pylori resistance to metronidazole and clarithromycin in the Finnish population. | 2004 | Aliment. Pharmacol. Ther. | pmid:15113368 |
| Catalano F et al. | Ranitidine bismuth citrate versus omeprazole triple therapy for the eradication of Helicobacter pylori and healing of duodenal ulcer. | 1998 | Aliment. Pharmacol. Ther. | pmid:9692702 |
| Dobrilla G et al. | Ranitidine bismuth citrate with either clarithromycin 1 g/day or 1.5 g/day is equally effective in the eradication of H. pylori and healing of duodenal ulcer. | 1998 | Aliment. Pharmacol. Ther. | pmid:9692703 |
| Gisbert JP and Pajares JM | Review article: Helicobacter pylori "rescue" regimen when proton pump inhibitor-based triple therapies fail. | 2002 | Aliment. Pharmacol. Ther. | pmid:12030945 |
| Laine L and Dhir V | Helicobacter pylori eradication does not worsen quality of life related to reflux symptoms: a prospective trial. | 2002 | Aliment. Pharmacol. Ther. | pmid:12030957 |
| Drouet M et al. | [Unusual clinical form of amoxicillin allergy]. | 1996 | Allerg Immunol (Paris) | pmid:9011169 |
| Can C et al. | Symmetrical drug-related intertriginous and flexural exanthema induced by two different antibiotics. | Allergol Immunopathol (Madr) | pmid:23253684 | |
| Gangemi S et al. | Immediate reaction to clarithromycin. | 2001 Jan-Feb | Allergol Immunopathol (Madr) | pmid:11449533 |
| Gaig P et al. | Efficacy of the eradication of Helicobacter pylori infection in patients with chronic urticaria. A placebo-controlled double blind study. | 2002 Sep-Oct | Allergol Immunopathol (Madr) | pmid:12396958 |
| Karakaya G et al. | Determining safe antibiotics for drug hypersensitive patients with the alternative method of double-triple test. | Allergol Immunopathol (Madr) | pmid:19080798 | |
| Malheiro D et al. | Nimesulide-induced fixed drug eruption. | 2005 Sep-Oct | Allergol Immunopathol (Madr) | pmid:16287549 |
| Seitz CS et al. | Suspicion of macrolide allergy after treatment of infectious diseases including Helicobacter pylori: results of allergological testing. | Allergol Immunopathol (Madr) | pmid:21269750 | |
| Moreira A et al. | Is Helicobacter pylori infection associated with chronic idiopathic urticaria? | Allergol Immunopathol (Madr) | pmid:12890412 | |
| Brož P et al. | Nonirritant intradermal skin test concentrations of ciprofloxacin, clarithromycin, and rifampicin. | 2012 | Allergy | pmid:22435670 |
| Igea JM and Lázaro M | Hypersensitivity reaction to clarithromycin. | 1998 | Allergy | pmid:9491242 |
| Ben-Shoshan M et al. | Anaphylactic reaction to clarithromycin in a child. | 2009 | Allergy | pmid:19222423 |
| Siddiqui S and Brightling CE | Airways disease: phenotyping heterogeneity using measures of airway inflammation. | 2007 | Allergy Asthma Clin Immunol | pmid:20525145 |
| Xepapadaki P et al. | Atypical bacteria and macrolides in asthma. | 2008 | Allergy Asthma Clin Immunol | pmid:20525132 |
| Desrosiers M et al. | Canadian clinical practice guidelines for acute and chronic rhinosinusitis. | 2011 | Allergy Asthma Clin Immunol | pmid:21310056 |
| Wedi B et al. | Urticaria and infections. | 2009 | Allergy Asthma Clin Immunol | pmid:20066173 |
| Thong BY | Update on the management of antibiotic allergy. | 2010 | Allergy Asthma Immunol Res | pmid:20358021 |
| Park SJ et al. | Fulminant and Fatal Multiple Organ Failure in a 12-Year-Old Boy With Mycoplasma pneumoniae Infection. | 2012 | Allergy Asthma Immunol Res | pmid:22211173 |
| Kim MH et al. | A case of chlorpheniramine maleate-induced hypersensitivity with aspirin intolerance. | 2011 | Allergy Asthma Immunol Res | pmid:21217928 |
| Hong SJ | The Role of Mycoplasma pneumoniae Infection in Asthma. | 2012 | Allergy Asthma Immunol Res | pmid:22379599 |
| Kariyawasam HH and Scadding GK | Chronic rhinosinusitis: therapeutic efficacy of anti-inflammatory and antibiotic approaches. | 2011 | Allergy Asthma Immunol Res | pmid:21966602 |
| Damianos AJ and McGarrity TJ | Treatment strategies for Helicobacter pylori infection. | 1997 | Am Fam Physician | pmid:9191460 |
| Karlstadt RG and Walker K | Update on prescribing information for pantoprazole. | 2003 | Am Fam Physician | pmid:12674447 |
| Gregory DS | Pertussis: a disease affecting all ages. | 2006 | Am Fam Physician | pmid:16913160 |
| Chaisson R | Clarithromycin is effective against M. avium complex in AIDS. | 1992 | Am Fam Physician | pmid:1456199 |
| Elston D | Nontuberculous mycobacterial skin infections: recognition and management. | 2009 | Am J Clin Dermatol | pmid:19658440 |
| Rebora A | The management of rosacea. | 2002 | Am J Clin Dermatol | pmid:12180896 |
| Scheinfeld N | Confluent and reticulated papillomatosis : a review of the literature. | 2006 | Am J Clin Dermatol | pmid:17007541 |
| Zeegelaar JE and Faber WR | Imported tropical infectious ulcers in travelers. | 2008 | Am J Clin Dermatol | pmid:18572973 |
| Chang SL et al. | Bilateral sporotrichoid lymphocutaneous dermatosis in a drug abuser: case report and review of the literature. | 2008 | Am J Clin Dermatol | pmid:18973406 |
| Wedi B and Kapp A | Helicobacter pylori infection in skin diseases: a critical appraisal. | 2002 | Am J Clin Dermatol | pmid:12010072 |
| Curth HM et al. | Effects of Helicobacter pylori Eradication in Chronic Spontaneous Urticaria: Results from a Retrospective Cohort Study. | 2015 | Am J Clin Dermatol | pmid:26334425 |
| Parsad D et al. | A guide to selection and appropriate use of macrolides in skin infections. | 2003 | Am J Clin Dermatol | pmid:12762831 |