clarithromycin

clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.

Cross Reference

Introduction

To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with clarithromycin?

clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with clarithromycin

MeSH term MeSH ID Detail
Abscess D000038 13 associated lipids
Radiation Injuries D011832 14 associated lipids
Encephalitis D004660 15 associated lipids
HIV Seropositivity D006679 15 associated lipids
Synovitis D013585 15 associated lipids
Bronchial Hyperreactivity D016535 15 associated lipids
Pneumonia, Bacterial D018410 16 associated lipids
Gram-Negative Bacterial Infections D016905 16 associated lipids
Dermatomycoses D003881 17 associated lipids
Ischemia D007511 18 associated lipids
Tuberculosis, Pulmonary D014397 18 associated lipids
Bronchial Spasm D001986 18 associated lipids
Peptic Ulcer D010437 19 associated lipids
Tuberculosis D014376 20 associated lipids
Drug Hypersensitivity D004342 20 associated lipids
Gastrointestinal Diseases D005767 20 associated lipids
Bacterial Infections D001424 21 associated lipids
Myocardial Infarction D009203 21 associated lipids
Helicobacter Infections D016481 21 associated lipids
Carcinoma, Lewis Lung D018827 22 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with clarithromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with clarithromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with clarithromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with clarithromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with clarithromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with clarithromycin?

Mouse Model

Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).

Knock-out

Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).

Experimental Pneumococcal Meningitis

Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with clarithromycin

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Per page 10 20 50 100 | Total 7636
Authors Title Published Journal PubMed Link
Adamek RJ et al. Modified short-term triple therapy--ranitidine, clarithromycin, and metronidazole--for cure of Helicobacter pylori infection. 1995 Am. J. Gastroenterol. pmid:7801936
FDA approves Biaxin for MAC prophylaxis. Food and Drug Administration. 1995 J Int Assoc Physicians AIDS Care pmid:11363096
Weits J and Sprenger HG [Surgical treatment of lymphadenitis caused by non-tuberculous mycobacteria in children]. 1995 Ned Tijdschr Geneeskd pmid:8524431
Ishii K et al. A new pharmacokinetic model including in vivo dissolution and gastrointestinal transit parameters. 1995 Biol. Pharm. Bull. pmid:7550125
Harris AW et al. Eradication of Helicobacter pylori with lansoprazole and clarithromycin. 1995 Aliment. Pharmacol. Ther. pmid:7605863
Katelaris PH et al. A randomized prospective comparison of clarithromycin versus amoxycillin in combination with omeprazole for eradication of Helicobacter pylori. 1995 Aliment. Pharmacol. Ther. pmid:7605864
Yousfi MM et al. Metronidazole, omeprazole and clarithromycin: an effective combination therapy for Helicobacter pylori infection. 1995 Aliment. Pharmacol. Ther. pmid:7605865
Forné M et al. Impact of colloidal bismuth subnitrate in the eradication rates of Helicobacter pylori infection-associated duodenal ulcer using a short treatment regimen with omeprazole and clarithromycin: a randomized study. 1995 Am. J. Gastroenterol. pmid:7733075
Tebas P et al. Rapid development of resistance to clarithromycin following monotherapy for disseminated Mycobacterium chelonae infection in a heart transplant patient. 1995 Clin. Infect. Dis. pmid:7742453
Moayyedi P et al. Efficacy and optimum dose of omeprazole in a new 1-week triple therapy regimen to eradicate Helicobacter pylori. 1995 Eur J Gastroenterol Hepatol pmid:8574714
Fujioka T et al. Peptic ulcer recurrence after Helicobacter pylori eradication: a 5-year follow-up study. 1995 Eur J Gastroenterol Hepatol pmid:8574733
Deltenre M et al. Omeprazole-based antimicrobial therapies: results in 198 Helicobacter pylori-positive patients. 1995 Eur J Gastroenterol Hepatol pmid:8574734
Fukuda Y et al. Combination therapy with mucosal protective agent for the eradication of Helicobacter pylori. 1995 Eur J Gastroenterol Hepatol pmid:8574735
Pavlopoulou J et al. Randomized controlled study of clarithromycin versus cefaclor suspensions in the treatment of acute otitis media in children. 1995 J Chemother pmid:8904139
Raffi F et al. Breakthrough cerebral toxoplasmosis in patients with AIDS who are being treated with clarithromycin. 1995 Clin. Infect. Dis. pmid:7795062
Sharma PK and Tami TA AIDS: lessons from the last decade and prospects for the future. 1995 Ear Nose Throat J pmid:7796740
Cama VA et al. Treatment of acute and chronic Cryptosporidium parvum infections in mice using clarithromycin and 14-OH clarithromycin. 1994 Sep-Oct J. Eukaryot. Microbiol. pmid:7804227
O'Connor NK and Fris J Clarithromycin-carbamazepine interaction in a clinical setting. 1994 Nov-Dec J Am Board Fam Pract pmid:7847111
Scaglione F et al. Effect of antibiotics on Bordetella pertussis adhering activity: hypothesis regarding mechanism of action. 1994 May-Jun Chemotherapy pmid:7515782
Gersema LM et al. Suspected drug interaction between cyclosporine and clarithromycin. 1994 Mar-Apr J. Heart Lung Transplant. pmid:8031821
Heifets LB Quantitative cultures and drug susceptibility testing of Mycobacterium avium clinical isolates before and during the antimicrobial therapy. 1994 Mar-Apr Res. Microbiol. pmid:7809471
Dautzenberg B Clinical trials in Mycobacterium avium therapy: lessons to take home. 1994 Mar-Apr Res. Microbiol. pmid:7809472
Winter J Intravenous clarithromycin. 1994 Mar 16-Apr 5 Br J Hosp Med pmid:8032567
Mor N et al. Accumulation of clarithromycin in macrophages infected with Mycobacterium avium. 1994 Jan-Feb Pharmacotherapy pmid:8159593
Tessier MH et al. Clarithromycin for atypical mycobacterial lymphadenitis in non-immunocompromised children. 1994 Dec 24-31 Lancet pmid:7997032
Darling TN et al. Treatment of Mycobacterium haemophilum infection with an antibiotic regimen including clarithromycin. 1994 Br. J. Dermatol. pmid:7918014
Domschke W Omeprazole, Helicobacter pylori, and gastritis. 1994 J. Gastroenterol. pmid:7921141
Geraci AJ Empiric antibiotics in sinusitis. 1994 Arch Fam Med pmid:7921288
Rust GS Multicenter comparison of clarithromycin and amoxicillin. 1994 Arch Fam Med pmid:7921290
Sano M et al. [Inhibition of biofilm formation by clarithromycin (CAM) in an experimental model of complicated bladder infection--in vitro study using automated simulation of urinary antimicrobial concentration]. 1994 Kansenshogaku Zasshi pmid:7829898
Sieber CC et al. [Helicobacter pylori resistance against metronidazole in Switzerland: implications for eradication therapy?]. 1994 Schweiz Med Wochenschr pmid:8091165
Dorrell L et al. Toxicity of clarithromycin in the treatment of Mycobacterium avium complex infection in a patient with AIDS. 1994 J. Antimicrob. Chemother. pmid:7868416
Labenz J and Stolte M [Current therapy of Helicobacter pylori infection]. 1994 Leber Magen Darm pmid:8145628
Logan RP et al. Eradication of Helicobacter pylori with clarithromycin and omeprazole. 1994 Gut pmid:8150340
Neri M et al. Omeprazole, bismuth and clarithromycin in the sequential treatment of Helicobacter pylori infection. 1994 Aliment. Pharmacol. Ther. pmid:7986974
[Recent advances in macrolide antibiotics: focused on clarithromycin. Discussion]. 1994 Jpn J Antibiot pmid:7990251
Alder J et al. Treatment of experimental Pneumocystis carinii infection by combination of clarithromycin and sulphamethoxazole. 1994 J. Antimicrob. Chemother. pmid:8182006
Tsang KW et al. The concentrations of clarithromycin and its 14-hydroxy metabolite in sputum of patients with bronchiectasis following single dose oral administration. 1994 J. Antimicrob. Chemother. pmid:8182010
Sundberg L and Cederberg A Penetration of clarithromycin and its 14-hydroxy metabolite into middle ear effusion in children with secretory otitis media. 1994 J. Antimicrob. Chemother. pmid:8182011
Klemens SP and Cynamon MH Intermittent azithromycin for treatment of Mycobacterium avium infection in beige mice. 1994 Antimicrob. Agents Chemother. pmid:7986001
[Zeclar, a new antibiotic (clarithromycin 250 mg from Abbott laboratories]. 1994 Rev Infirm pmid:7652424
Cynamon MH et al. Comparative activities of azithromycin and clarithromycin against Mycobacterium avium infection in beige mice. 1994 Antimicrob. Agents Chemother. pmid:7979270
Yoshida K et al. Chlamydia trachomatis infection in the semen of asymptomatic infertile men: detection of the antigen by in situ hybridization. 1994 Urol. Int. pmid:7855940
Laing RB et al. New antimicrobials against Mycobacterium marinum infection. 1994 Br. J. Dermatol. pmid:7857853
Spiegl PV and Feiner CM Mycobacterium phlei infection of the foot: a case report. 1994 Foot Ankle Int pmid:7894643
Walker KJ et al. Evaluation of antimicrobial activities of clarithromycin and 14-hydroxyclarithromycin against three strains of Haemophilus influenzae by using an in vitro pharmacodynamic model. 1994 Antimicrob. Agents Chemother. pmid:7811010
Price DA et al. Clinical response to the addition of clarithromycin in Pneumocystis carinii pneumonia refractory to high dose co-trimoxazole. 1994 J. Antimicrob. Chemother. pmid:7814298
Tahara RW et al. The question of clarithromycin: a first-line drug for sinusitis? 1994 Arch Fam Med pmid:7818657
Pustorino S et al. [Effects of intravenous administration of clarithromycin on plasma levels of gastrin and group I pepsinogen]. 1994 Clin Ter pmid:7820984
Alder J et al. Treatment of experimental Toxoplasma gondii infection by clarithromycin-based combination therapy with minocycline or pyrimethamine. 1994 J. Acquir. Immune Defic. Syndr. pmid:7932081