clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with clarithromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (2)
- FEMS Immunol. Med. Microbiol. (1)
- J. Antimicrob. Chemother. (1)
- Others (2)
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Sillakivi T et al. | An attempt at Helicobacter pylori eradication with intravenous clarithromycin in perforated peptic ulcer patients. | 2001 | Scand. J. Gastroenterol. | pmid:11589389 |
| Tulassay Z et al. | Twelve-month endoscopic and histological analysis following proton-pump inhibitor-based triple therapy in Helicobacter pylori-positive patients with gastric ulcers. | 2010 | Scand. J. Gastroenterol. | pmid:20509752 |
| Marignani M et al. | Reversal of long-standing iron deficiency anaemia after eradication of Helicobacter pylori infection. | 1997 | Scand. J. Gastroenterol. | pmid:9200297 |
| Valooran GJ et al. | Sequential therapy versus standard triple drug therapy for eradication of Helicobacter pylori in patients with perforated duodenal ulcer following simple closure. | 2011 | Scand. J. Gastroenterol. | pmid:21627398 |
| Kajihara Y et al. | Analysis of the cost-effectiveness of using vonoprazan-amoxicillin-clarithromycin triple therapy for first-line Helicobacter pylori eradication. | 2017 | Scand. J. Gastroenterol. | pmid:27806639 |
| Ogura K et al. | Clarithromycin-based triple therapy for non-resistant Helicobacter pylori infection. How long should it be given? | 2001 | Scand. J. Gastroenterol. | pmid:11424316 |
| Hojo M et al. | Pooled analysis on the efficacy of the second-line treatment regimens for Helicobacter pylori infection. | 2001 | Scand. J. Gastroenterol. | pmid:11444467 |
| Ashorn M et al. | Helicobacter pylori and iron deficiency anaemia in children. | 2001 | Scand. J. Gastroenterol. | pmid:11444468 |
| Masuda H et al. | Necessity of multiple gastric biopsies from different sites for detection of clarithromycin-resistant Helicobacter pylori strains. | 2003 | Scand. J. Gastroenterol. | pmid:14531530 |
| Ellenrieder V et al. | Prevalence of resistance to clarithromycin and its clinical impact on the efficacy of Helicobacter pylori eradication. | 1999 | Scand. J. Gastroenterol. | pmid:10499474 |
| Ochi M et al. | Regression of primary low-grade mucosa-associated lymphoid tissue lymphoma of duodenum after long-term treatment with clarithromycin. | 2006 | Scand. J. Gastroenterol. | pmid:16497629 |
| Unge P et al. | Do Japanese and Swedish peptic ulcer patients respond differently to Helicobacter pylori eradication therapies and what are their histological features? | 2003 | Scand. J. Gastroenterol. | pmid:12795457 |
| de Boer WA and Tytgat GN | The best therapy for Helicobacter pylori infection: should efficacy or side-effect profile determine our choice? | 1995 | Scand. J. Gastroenterol. | pmid:7638563 |
| Seppälä K et al. | Cure of Helicobacter pylori infection in all compliant patients: report on 644 subjects. | 2008 | Scand. J. Gastroenterol. | pmid:18609180 |
| Khan Z et al. | Does Helicobacter pylori eradication reduce the long-term requirements for acid suppressants in patients with a history of peptic ulcer disease in general practice? Results from a four-year longitudinal study. | 2002 | Scand. J. Gastroenterol. | pmid:11843048 |
| Gasbarrini A et al. | Efficacy of different Helicobacter pylori eradication regimens in patients affected by insulin-dependent diabetes mellitus. | 2000 | Scand. J. Gastroenterol. | pmid:10766318 |
| Fiorini G et al. | Antibiotic resistance pattern of Helicobacter pylori strains isolated in Italy during 2010-2016. | 2018 | Scand. J. Gastroenterol. | pmid:29688095 |
| Abut E et al. | Effect of the mucolytic erdosteine on the success rate of PPI-based first-line triple therapy for Helicobacter pylori eradication: a prospective, double-blind, randomized, placebo-controlled study. | 2010 | Scand. J. Gastroenterol. | pmid:20334478 |
| Pedrazzoli J et al. | Transfer of clarithromycin to gastric juice is enhanced by omeprazole in Helicobacter pylori-infected individuals. | 2001 | Scand. J. Gastroenterol. | pmid:11761012 |
| Li H et al. | Inappropriate treatment in Helicobacter pylori eradication failure: a retrospective study. | 2018 | Scand. J. Gastroenterol. | pmid:29214879 |
| Raymond J et al. | Diagnosis of Helicobacter pylori recurrence: relapse or reinfection? Usefulness of molecular tools. | 2016 | Scand. J. Gastroenterol. | pmid:26784882 |
| Lerang F et al. | Highly effective second-line anti-Helicobacter pylori therapy in patients with previously failed metronidazole-based therapy. | 1997 | Scand. J. Gastroenterol. | pmid:9438318 |
| Testoni PA and Bagnolo F | In dyspeptic patients without gastric phase III of the migrating motor complex, Helicobacter pylori eradication produces no short-term changes in interdigestive motility pattern. | 2000 | Scand. J. Gastroenterol. | pmid:10994618 |
| Di Giulio M et al. | In vitro antimicrobial susceptibility of Helicobacter pylori to nine antibiotics currently used in Central Italy. | 2016 | Scand. J. Gastroenterol. | pmid:26554617 |
| Lee JW et al. | A comparison between 15-day sequential, 10-day sequential and proton pump inhibitor-based triple therapy for Helicobacter pylori infection in Korea. | 2014 | Scand. J. Gastroenterol. | pmid:24988873 |
| Cellini L et al. | Analysis of genetic variability, antimicrobial susceptibility and virulence markers in Helicobacter pylori identified in Central Italy. | 2006 | Scand. J. Gastroenterol. | pmid:16497614 |
| Lee JW et al. | GenoType HelicoDR test in the determination of antimicrobial resistance of Helicobacter pylori in Korea. | 2014 | Scand. J. Gastroenterol. | pmid:24957849 |
| Tepes B | Comparison of two invasive diagnostic tests for Helicobacter pylori after antimicrobial therapy. | 2007 | Scand. J. Gastroenterol. | pmid:17354112 |
| Gisbert JP et al. | Second-line rescue triple therapy with levofloxacin after failure of non-bismuth quadruple "sequential" or "concomitant" treatment to eradicate H. pylori infection. | 2013 | Scand. J. Gastroenterol. | pmid:23556551 |
| Gisbert JP et al. | Unhealed duodenal ulcers despite Helicobacter pylori eradication. | 1997 | Scand. J. Gastroenterol. | pmid:9246702 |
| Parente F et al. | Effects of Helicobacter pylori eradication on gastric function indices in functional dyspepsia. A prospective controlled study. | 1998 | Scand. J. Gastroenterol. | pmid:9648983 |
| Apostolopoulos P et al. | Concomitant versus sequential therapy for the treatment of Helicobacter pylori infection: a Greek randomized prospective study. | 2016 | Scand. J. Gastroenterol. | pmid:26435055 |
| Doorakkers E et al. | Helicobacter pylori eradication in the Swedish population. | Scand. J. Gastroenterol. | pmid:28323552 | |
| Tsukada K et al. | Seven-day triple therapy with omeprazole, amoxycillin and clarithromycin for Helicobacter pylori infection in haemodialysis patients. | 2002 | Scand. J. Gastroenterol. | pmid:12465723 |
| Murakami K et al. | Comparison of the efficacy of irsogladine maleate and famotidine for the healing of gastric ulcers after Helicobacter pylori eradication therapy: a randomized, controlled, prospective study. | 2011 | Scand. J. Gastroenterol. | pmid:21073372 |
| Ribaldone DG et al. | Helicobacter pylori eradication: poor medical compliance from East to West of the world. | 2018 | Scand. J. Gastroenterol. | pmid:29383955 |
| Bjerre M et al. | Osteoprotegerin independently predicts mortality in patients with stable coronary artery disease: the CLARICOR trial. | 2014 | Scand. J. Clin. Lab. Invest. | pmid:25026506 |
| Paakkanen R et al. | Beneficial effect of clarithromycin in patients with acute coronary syndrome and complement C4 deficiencies. | 2009 | Scand. Cardiovasc. J. | pmid:19365786 |
| Alfaresi MS et al. | Molecular prevalence of point mutations conferring resistance to clarithromycin in Helicobacter pylori in the United Arab Emirates. | 2005 | Saudi Med J | pmid:15951866 |
| Ghazzawi IM et al. | Triple therapy with pantoprazole, clarithromycin and amoxicillin for eradication in patients with Helicobacter pylori positive duodenal ulcers. | 2004 | Saudi Med J | pmid:15322588 |
| Al-Mobeireek AF | Rapidly growing mycobacterial pulmonary infection in association with severe gastroesophageal reflux disease. | 2002 | Saudi Med J | pmid:12174240 |
| Celen MK et al. | Development of pneumatoceles after viral infection. | 2006 | Saudi Med J | pmid:16830037 |
| Bindayna KM | Antibiotic susceptibilities of Helicobacter pylori. | 2001 | Saudi Med J | pmid:11255612 |
| Ranganathan D et al. | Mycobacterium fortuitum peritonitis in a patient receiving continuous ambulatory peritoneal dialysis. | 2013 | Saudi J Kidney Dis Transpl | pmid:24029271 |
| Vafaeimanesh J et al. | Expression comparison of azithromycin and clarithromycin in triple-therapy regimens for eradication of Helicobacter pylori in hemodialysis patients. | 2014 | Saudi J Kidney Dis Transpl | pmid:24434382 |
| Dajani AI et al. | Do probiotics improve eradication response to Helicobacter pylori on standard triple or sequential therapy? | 2013 May-Jun | Saudi J Gastroenterol | pmid:23680708 |
| Shokrzadeh L et al. | Antibiotic susceptibility profile of Helicobacter pylori isolated from the dyspepsia patients in Tehran, Iran. | Saudi J Gastroenterol | pmid:21727733 | |
| Hasan SR et al. | Short-duration furazolidone therapy in combination with amoxicillin, bismuth subcitrate, and omeprazole for eradication of Helicobacter pylori. | Saudi J Gastroenterol | pmid:20065568 | |
| Bezmin Abadi AT et al. | Inefficiency of rapid urease test for confirmation of Helicobacter pylori. | Saudi J Gastroenterol | pmid:21196663 | |
| Rajindrajith S et al. | Helicobacter pylori infection in children. | 2009 | Saudi J Gastroenterol | pmid:19568571 |