clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with clarithromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (5)
- Drug Metab. Dispos. (1)
- FEMS Immunol. Med. Microbiol. (1)
- Others (5)
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kunin M et al. | Mycobacterium chelonae peritonitis in peritoneal dialysis. Literature review. | 2014 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:24569948 |
| Fan Y et al. | High and low doses of clarithromycin treatment are associated with different clinical efficacies and immunomodulatory properties in chronic rhinosinusitis. | 2014 | J Laryngol Otol | pmid:24555753 |
| Miwa S et al. | Efficacy of clarithromycin and ethambutol for Mycobacterium avium complex pulmonary disease. A preliminary study. | 2014 | Ann Am Thorac Soc | pmid:24298907 |
| Kakuda TN et al. | Pharmacokinetic evaluation of the interaction between etravirine and rifabutin or clarithromycin in HIV-negative, healthy volunteers: results from two Phase 1 studies. | 2014 | J. Antimicrob. Chemother. | pmid:24155058 |
| Seung KJ et al. | Salvage therapy for multidrug-resistant tuberculosis. | 2014 | Clin. Microbiol. Infect. | pmid:23991934 |
| Yakoob J et al. | Comparison of antimicrobial activity of zinc chloride and bismuth subsalicylate against clinical isolates of Helicobacter pylori. | 2014 | Microb. Drug Resist. | pmid:23844851 |
| Kathariya R et al. | Evaluation of subgingivally delivered 0.5% clarithromycin as an adjunct to nonsurgical mechanotherapy in the management of chronic periodontitis: a short-term double blinded randomized control trial. | 2014 | J Investig Clin Dent | pmid:23097216 |
| Bjerre M et al. | Osteoprotegerin independently predicts mortality in patients with stable coronary artery disease: the CLARICOR trial. | 2014 | Scand. J. Clin. Lab. Invest. | pmid:25026506 |
| Khoshnood A et al. | Replacement of clarithromycin with azithromycin in triple therapy regimens for the eradication of Helicobacter pylori: A randomized clinical trial. | 2014 | J Med Life | pmid:25408735 |
| Noh TK et al. | Infection with Mycobacterium fortuitum during acupoint embedding therapy. | 2014 | J. Am. Acad. Dermatol. | pmid:24831334 |
| Fowler J and Mahlen SD | Localized cutaneous infections in immunocompetent individuals due to rapidly growing mycobacteria. | 2014 | Arch. Pathol. Lab. Med. | pmid:25076301 |
| Ueda Y et al. | [Obstructive pneumonia and brain abscess due to Nocardia elegans in a patient with systemic lupus erythematosus]. | 2014 | Kansenshogaku Zasshi | pmid:24974451 |
| NegrÃn-González J et al. | Psychiatric adverse reaction induced by clarithromycin. | 2014 | Eur Ann Allergy Clin Immunol | pmid:24853570 |
| Kurosaki Y et al. | [Two cases of pulmonary Mycobacterium avium complex disease with resistance to clarithromycin]. | 2014 | Kekkaku | pmid:24979948 |
| Iwanaga K and Carter ER | Mycobacterium abscessus complex lung infection in a toddler with a tracheostomy. | 2014 | Pediatr. Pulmonol. | pmid:23460506 |
| Loreto ES et al. | New insights into the in vitro susceptibility of Pythium insidiosum. | 2014 | Antimicrob. Agents Chemother. | pmid:25223997 |
| Tümgör G et al. | Comparison of standard and standard plus vitamin E therapy for Helicobacter pylori eradications in children. | 2014 | Turk J Gastroenterol | pmid:25910378 |
| Çiftci İH et al. | Comparison of FISH, RFLP and agar dilution methods for testing clarithromycin resistance of Helicobacter pylori. | 2014 | Turk J Gastroenterol | pmid:25910373 |
| De Francesco V et al. | Change of point mutations in Helicobacter pylori rRNA associated with clarithromycin resistance in Italy. | 2014 | J. Med. Microbiol. | pmid:24344205 |
| Lee JY et al. | Factors affecting first-line triple therapy of Helicobacter pylori including CYP2C19 genotype and antibiotic resistance. | 2014 | Dig. Dis. Sci. | pmid:24599773 |
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| Ohe M and Hashino S | Successful treatment of primary immune thrombocytopenia in aged patients using clarithromycin. | 2014 | J. Formos. Med. Assoc. | pmid:24630039 |
| Zhou L et al. | A comparative study of sequential therapy and standard triple therapy for Helicobacter pylori infection: a randomized multicenter trial. | 2014 | Am. J. Gastroenterol. | pmid:24642580 |
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| Patsche CB et al. | Disseminated Mycobacterium celatum disease with prolonged pulmonary involvement. | 2014 | Int. J. Infect. Dis. | pmid:25008771 |
| Jesus FP et al. | In vitro synergism observed with azithromycin, clarithromycin, minocycline, or tigecycline in association with antifungal agents against Pythium insidiosum. | 2014 | Antimicrob. Agents Chemother. | pmid:25001300 |
| Mendu ML and Waikar SS | Drug-drug interactions and acute kidney injury: caveat prescriptor. | 2014 | Am. J. Kidney Dis. | pmid:24820318 |
| Vu DH et al. | Simultaneous determination of rifampicin, clarithromycin and their metabolites in dried blood spots using LC-MS/MS. | 2014 | Talanta | pmid:24607103 |
| Zaiem A et al. | Clarithromycin induced psoriasis in a 37-year old man. | 2014 | Curr Drug Saf | pmid:24410388 |
| de Masson A et al. | Cavitary pulmonary disease in a patient treated with natalizumab. | 2014 | Presse Med | pmid:24742610 |
| Furuta T et al. | Sitafloxacin-based third-line rescue regimens for Helicobacter pylori infection in Japan. | 2014 | J. Gastroenterol. Hepatol. | pmid:24224808 |
| Page SR and Yee KC | Rhabdomyolysis in association with simvastatin and dosage increment in clarithromycin. | 2014 | Intern Med J | pmid:25041770 |
| Noguchi S et al. | Polymorphic transformation of antibiotic clarithromycin under acidic condition. | 2014 | J Pharm Sci | pmid:24375227 |
| Methaneethorn J et al. | A pharmacokinetic drug-drug interaction model of simvastatin and clarithromycin in humans. | 2014 | Conf Proc IEEE Eng Med Biol Soc | pmid:25571290 |
| Phillips RO et al. | Clinical and bacteriological efficacy of rifampin-streptomycin combination for two weeks followed by rifampin and clarithromycin for six weeks for treatment of Mycobacterium ulcerans disease. | 2014 | Antimicrob. Agents Chemother. | pmid:24323473 |
| Hajaghamohammadi A et al. | Low dose furazolidone for eradication of H- pylori instead of clarithromycin: a clinical trial. | 2014 | Glob J Health Sci | pmid:25560342 |
| Iwanczak B et al. | Genotypic and clinical differences of seropositive Helicobacter pylori children and adults in the Polish population. | 2014 | J. Physiol. Pharmacol. | pmid:25554984 |
| McNicholl AG et al. | Randomised clinical trial comparing sequential and concomitant therapies for Helicobacter pylori eradication in routine clinical practice. | 2014 | Gut | pmid:23665990 |
| Rakici H et al. | Comparison of levofloxacin- and moxifloxacin-based triple therapies with standard treatment in eradication of Helicobacter pylori as first-line therapy. | 2014 | Digestion | pmid:25547786 |
| Karamanolis GP et al. | The evolution of Helicobacter pylori antibiotics resistance over 10 years in Greece. | 2014 | Digestion | pmid:25531953 |
| Kim SY et al. | [Ten day concomitant therapy is superior to ten day sequential therapy for Helicobacter pylori eradication]. | 2014 | Korean J Gastroenterol | pmid:25420735 |
| Mustafa G and Necati B | Clarithromycin-associated rhabdomyolysis in an infant. | 2014 | J Clin Rheumatol | pmid:25417692 |
| Hashim H et al. | Eradication of Helicobacter pylori infection improves levodopa action, clinical symptoms and quality of life in patients with Parkinson's disease. | 2014 | PLoS ONE | pmid:25411976 |
| Yangco BG et al. | Is primary mycobacterium avium complex prophylaxis necessary in patients with CD4 <50 cells/μL who are virologically suppressed on cART? | 2014 | AIDS Patient Care STDS | pmid:24833016 |
| Veraldi S et al. | Treatment of sporotrichoid fish tank granuloma with pulsed clarithromycin. | 2014 | Dermatology (Basel) | pmid:25228273 |
| Phillips RO et al. | Reply to "compliance with antimicrobial therapy for buruli ulcer". | 2014 | Antimicrob. Agents Chemother. | pmid:25225343 |
| Klis S et al. | Compliance with antimicrobial therapy for buruli ulcer. | 2014 | Antimicrob. Agents Chemother. | pmid:25225342 |
| Mitui M et al. | Novel Helicobacter pylori sequencing test identifies high rate of clarithromycin resistance. | 2014 | J. Pediatr. Gastroenterol. Nutr. | pmid:25222804 |
| Gold BD | Resistance testing for Helicobacter pylori infection: is it finally ready for prime time? | 2014 | J. Pediatr. Gastroenterol. Nutr. | pmid:25222802 |
| Morakul B et al. | Dissolution enhancement and in vitro performance of clarithromycin nanocrystals produced by precipitation-lyophilization-homogenization method. | 2014 | Eur J Pharm Biopharm | pmid:25201298 |
| Parekh TM et al. | Hypoglycemia after antimicrobial drug prescription for older patients using sulfonylureas. | 2014 | JAMA Intern Med | pmid:25179404 |
| Kutluk G et al. | Sequential therapy versus standard triple therapy for Helicobacter pylori eradication in children: any advantage in clarithromycin-resistant strains? | 2014 | Eur J Gastroenterol Hepatol | pmid:25171023 |
| Higashi F et al. | Additional treatment with clarithromycin reduces fever duration in patients with influenza. | 2014 | Respir Investig | pmid:25169846 |
| Elkhatib W and Noreddin A | Efficacy of ciprofloxacin-clarithromycin combination against drug-resistant Pseudomonas aeruginosa mature biofilm using in vitro experimental model. | 2014 | Microb. Drug Resist. | pmid:25050970 |
| Ohe M and Bohgaki T | Successful treatment with clarithromycin for patients with polymyalgia rheumatica. | 2014 | Korean J. Intern. Med. | pmid:25045305 |
| Martin JH and Coombes I | Mortality from common drug interactions systems, knowledge and clinical reasoning to optimise prescribing. | 2014 | Intern Med J | pmid:25041768 |
| Bansal S and Chhibber S | Phytochemical-induced reduction of pulmonary inflammation during Klebsiella pneumoniae lung infection in mice. | 2014 | J Infect Dev Ctries | pmid:25022293 |
| Fouka E et al. | Low-dose clarithromycin therapy modulates Th17 response in non-cystic fibrosis bronchiectasis patients. | 2014 | Lung | pmid:25016929 |
| Lambert D et al. | Gastritis due to Helicobacter pylori, an unusual cause of chronic diarrhoea in HIV infected patients. | 2014 | Med Mal Infect | pmid:25015308 |
| Dalbøge CS et al. | Pharmacokinetic variability of clarithromycin and differences in CYP3A4 activity in patients with cystic fibrosis. | 2014 | J. Cyst. Fibros. | pmid:24035278 |
| Teh X et al. | Functional and molecular surveillance of Helicobacter pylori antibiotic resistance in Kuala Lumpur. | 2014 | PLoS ONE | pmid:25003707 |
| Lyons J et al. | An unusual lung mass post stem cell transplantation. | 2014 | Transpl Infect Dis | pmid:24995624 |
| DiCicco M et al. | In vitro synergism of fosfomycin and clarithromycin antimicrobials against methicillin-resistant Staphylococcus pseudintermedius. | 2014 | BMC Microbiol. | pmid:24886369 |
| Noonan KA et al. | Targeting immune suppression with PDE5 inhibition in end-stage multiple myeloma. | 2014 | Cancer Immunol Res | pmid:24878583 |
| Gong EJ et al. | Meta-analysis of first-line triple therapy for helicobacter pylori eradication in Korea: is it time to change? | 2014 | J. Korean Med. Sci. | pmid:24851029 |
| Jeon HK and Kim GH | Does standard triple therapy still have a role in first-line Helicobacter pylori eradication in Korea? | 2014 | J. Korean Med. Sci. | pmid:24851014 |
| Rasheed F et al. | Analysis of clinical isolates of Helicobacter pylori in Pakistan reveals high degrees of pathogenicity and high frequencies of antibiotic resistance. | 2014 | Helicobacter | pmid:24827414 |
| Wang Y et al. | Efficacy and safety of ecabet sodium as an adjuvant therapy for Helicobacter pylori eradication: a systematic review and meta-analysis. | 2014 | Helicobacter | pmid:24826809 |
| Graham DY et al. | Rational Helicobacter pylori therapy: evidence-based medicine rather than medicine-based evidence. | 2014 | Clin. Gastroenterol. Hepatol. | pmid:23751282 |
| Pan-In P et al. | Ethyl cellulose nanoparticles: clarithomycin encapsulation and eradication of H. pylori. | 2014 | Carbohydr Polym | pmid:24815396 |
| Ichihara A et al. | Case of disseminated cutaneous Mycobacterium chelonae infection mimicking cutaneous vasculitis. | 2014 | J. Dermatol. | pmid:24801916 |
| Togami K et al. | Involvement of intestinal permeability in the oral absorption of clarithromycin and telithromycin. | 2014 | Biopharm Drug Dispos | pmid:24801141 |
| Bernut A et al. | In vivo assessment of drug efficacy against Mycobacterium abscessus using the embryonic zebrafish test system. | 2014 | Antimicrob. Agents Chemother. | pmid:24798271 |
| Tursi A et al. | Decreasing efficacy of the standard seven-day triple therapy containing amoxycillin and clarithromycin in curing Helicobacter pylori infection in clinical setting in Italy: a 10-year follow-up study. | 2014 | Panminerva Med | pmid:24637473 |
| Wei Z et al. | Rome III criteria cannot distinguish patients with chronic gastritis from those functional dyspepsia patients. | 2014 | Helicobacter | pmid:24617669 |
| Wu JY et al. | Feasibility of shortening 14-day hybrid therapy while maintaining an excellent Helicobacter pylori eradication rate. | 2014 | Helicobacter | pmid:24612093 |
| Settin A et al. | Cure rate of Helicobacter pylori infection in Egyptian children related to CYP2C19 gene polymorphism. | 2014 | Indian J Gastroenterol | pmid:24610583 |
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| Okame M et al. | Complete regression of early-stage gastric diffuse large B-cell lymphoma in an HIV-1-infected patient following Helicobacter pylori eradication therapy. | 2014 | Clin. Infect. Dis. | pmid:24585569 |
| Mark TM et al. | Thalidomide, clarithromycin, lenalidomide and dexamethasone therapy in newly diagnosed, symptomatic multiple myeloma. | 2014 | Leuk. Lymphoma | pmid:24576165 |
| Takazono T et al. | Paradoxical response to disseminated non-tuberculosis mycobacteriosis treatment in a patient receiving tumor necrosis factor-α inhibitor: a case report. | 2014 | BMC Infect. Dis. | pmid:24576098 |
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| Suzaki I et al. | Enhancement of thioredoxin production from nasal epithelial cells by the macrolide antibiotic, clarithromycin in vitro. | 2013 May-Jun | In Vivo | pmid:23606690 |
| Dajani AI et al. | Do probiotics improve eradication response to Helicobacter pylori on standard triple or sequential therapy? | 2013 May-Jun | Saudi J Gastroenterol | pmid:23680708 |
| Petitto J et al. | Successful clarithromycin desensitization in a macrolide-sensitive pediatric patient. | 2013 May-Jun | J Allergy Clin Immunol Pract | pmid:24565493 |
| Cottle LE et al. | A multinational outbreak of histoplasmosis following a biology field trip in the Ugandan rainforest. | 2013 Mar-Apr | J Travel Med | pmid:23464714 |
| Molina-Infante J and Gisbert JP | [Update on the efficacy of triple therapy for Helicobacter pylori infection and clarithromycin resistance rates in Spain (2007-2012)]. | 2013 Jun-Jul | Gastroenterol Hepatol | pmid:23623461 |
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| Mandras N et al. | Antibacterial efficacy and drug-induced tooth discolouration of antibiotic combinations for endodontic regenerative procedures. | 2013 Apr-Jun | Int J Immunopathol Pharmacol | pmid:23755774 |
| Trespalacios AA et al. | Phenotypic and genotypic analysis of clarithromycin-resistant Helicobacter pylori from Bogotá D.C., Colombia. | 2013 | J. Microbiol. | pmid:23990295 |
| Guo L et al. | Refining the human iPSC-cardiomyocyte arrhythmic risk assessment model. | 2013 | Toxicol. Sci. | pmid:24052561 |
| Yano K et al. | Clinical outcome of the chronic flexor tenosynovitis in the hand caused by non-tuberculous mycobacterium treated by extensive tenosynovectomy and drugs. | 2013 | J Plast Surg Hand Surg | pmid:23875916 |
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| Zhou L et al. | Cutaneous Mycobacterium intracellulare infection in an immuno-competent person. | 2013 | Acta Derm. Venereol. | pmid:23532357 |
| Quinney SK et al. | Rate of onset of inhibition of gut-wall and hepatic CYP3A by clarithromycin. | 2013 | Eur. J. Clin. Pharmacol. | pmid:22777148 |