MeSH term | MeSH ID | Detail |
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Lung Neoplasms | D008175 | 171 associated lipids |
Body Weight | D001835 | 333 associated lipids |
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with clarithromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Owen RJ et al. | Effect of clarithromycin and omeprazole therapy on the diversity and stability of genotypes of Helicobacter pylori from duodenal ulcer patients. | 1999 | Microb. Drug Resist. | pmid:10432275 |
Baena DÃez JM et al. | [Are 5 days of omeprazole plus 2 antibiotics enough for eradication of H. pylori? Comments on sample size]. | 1999 | Rev Clin Esp | pmid:10432821 |
Schmitt H et al. | Successful treatment of pulmonary Mycobacterium xenopi infection in a natural killer cell-deficient patient with clarithromycin, rifabutin, and sparfloxacin. | 1999 | Clin. Infect. Dis. | pmid:10433574 |
Cohn DL et al. | A prospective randomized trial of four three-drug regimens in the treatment of disseminated Mycobacterium avium complex disease in AIDS patients: excess mortality associated with high-dose clarithromycin. Terry Beirn Community Programs for Clinical Research on AIDS. | 1999 | Clin. Infect. Dis. | pmid:10433575 |
Lipsky BA et al. | Treating acute bacterial exacerbations of chronic bronchitis in patients unresponsive to previous therapy: sparfloxacin versus clarithromycin. | 1999 | Clin Ther | pmid:10440620 |
Shimada N et al. | [A case of acute renal failure with rhabdomyolysis caused by the interaction of theophylline and clarithromycin]. | 1999 | Nihon Jinzo Gakkai Shi | pmid:10441997 |
Bazzoli F | My approach to Helicobacter pylori eradication. | 1999 | Eur J Gastroenterol Hepatol | pmid:10443911 |
Ali' A et al. | A second-line anti-Helicobacter pylori therapy in patients with previously failed treatment. | 1999 | Am. J. Gastroenterol. | pmid:10445583 |
Hewitt RG et al. | Prevention of disseminated Mycobacterium avium complex infection with reduced dose clarithromycin in patients with advanced HIV disease. | 1999 | AIDS | pmid:10449290 |
Enroth H et al. | Occurence of resistance mutation and clonal expansion in Helicobacter pylori multiple-strain infection: a potential risk in clarithromycin-based therapy. | 1999 | Clin. Infect. Dis. | pmid:10451171 |
Anzueto A et al. | The infection-free interval: its use in evaluating antimicrobial treatment of acute exacerbation of chronic bronchitis. | 1999 | Clin. Infect. Dis. | pmid:10451195 |
Gordin FM et al. | A randomized, placebo-controlled study of rifabutin added to a regimen of clarithromycin and ethambutol for treatment of disseminated infection with Mycobacterium avium complex. | 1999 | Clin. Infect. Dis. | pmid:10452638 |
Pandita D and Carson PJ | Thyroid abscess caused by Mycobacterium chelonae. | 1999 | Clin. Infect. Dis. | pmid:10452671 |
Härtig G et al. | [Symptomatic psychosis in bland sinus thrombosis and antibiotic therapy]. | 1999 | Psychiatr Prax | pmid:10457975 |
Labenz J and Stolte M | [Is lack of stomach carcinoma prevention by Helicobacter pylori eradication unethical?]. | 1999 | Z Gastroenterol | pmid:10458014 |
Boyanova L et al. | Characteristics and trends in macrolide resistance among Helicobacter pylori strains isolated in Bulgaria over four years. | 1999 | Diagn. Microbiol. Infect. Dis. | pmid:10459482 |
Sendi PP et al. | Systematic validation of disease models for pharmacoeconomic evaluations. Swiss HIV Cohort Study. | 1999 | J Eval Clin Pract | pmid:10461580 |
Gooderham MJ et al. | Concomitant digoxin toxicity and warfarin interaction in a patient receiving clarithromycin. | 1999 Jul-Aug | Ann Pharmacother | pmid:10466907 |
Gschwantler M et al. | Famotidine versus omeprazole in combination with clarithromycin and metronidazole for eradication of Helicobacter pylori--a randomized, controlled trial. | 1999 | Aliment. Pharmacol. Ther. | pmid:10468682 |
Paré P et al. | Comparison of ranitidine bismuth citrate plus clarithromycin with omeprazole plus clarithromycin for the eradication of Helicobacter pylori. | 1999 | Aliment. Pharmacol. Ther. | pmid:10468683 |