MeSH term | MeSH ID | Detail |
---|---|---|
Sacroiliitis | D058566 | 1 associated lipids |
Chlamydial Pneumonia | D061387 | 2 associated lipids |
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with clarithromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Stout JE and Floto RA | Treatment of Mycobacterium abscessus: all macrolides are equal, but perhaps some are more equal than others. | 2012 | Am. J. Respir. Crit. Care Med. | pmid:23118083 |
Bates JH | Mycobacterium avium disease: progress at last. | 1996 | Am. J. Respir. Crit. Care Med. | pmid:8665029 |
Wallace RJ et al. | Clarithromycin regimens for pulmonary Mycobacterium avium complex. The first 50 patients. | 1996 | Am. J. Respir. Crit. Care Med. | pmid:8665032 |
Frothingham R | Clarithromycin treatment for Mycobacterium avium-intracellulare complex lung disease. | 1996 | Am. J. Respir. Crit. Care Med. | pmid:8665069 |
Nakanishi Y et al. | Clarithromycin prevents smoke-induced emphysema in mice. | 2009 | Am. J. Respir. Crit. Care Med. | pmid:19060231 |
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Jeong BH et al. | Intermittent antibiotic therapy for nodular bronchiectatic Mycobacterium avium complex lung disease. | 2015 | Am. J. Respir. Crit. Care Med. | pmid:25393520 |
Koh WJ et al. | Therapeutic drug monitoring in the treatment of Mycobacterium avium complex lung disease. | 2012 | Am. J. Respir. Crit. Care Med. | pmid:22878282 |
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Tanaka E et al. | Effect of clarithromycin regimen for Mycobacterium avium complex pulmonary disease. | 1999 | Am. J. Respir. Crit. Care Med. | pmid:10471610 |
Shimizu T et al. | In vivo and in vitro effects of macrolide antibiotics on mucus secretion in airway epithelial cells. | 2003 | Am. J. Respir. Crit. Care Med. | pmid:12829454 |
Wallace RJ et al. | Initial clarithromycin monotherapy for Mycobacterium avium-intracellulare complex lung disease. | 1994 | Am. J. Respir. Crit. Care Med. | pmid:8173775 |
Koh WJ et al. | Clinical significance of differentiation of Mycobacterium massiliense from Mycobacterium abscessus. | 2011 | Am. J. Respir. Crit. Care Med. | pmid:20833823 |
Yanagihara K et al. | Effect of clarithromycin on lymphocytes in chronic respiratory Pseudomonas aeruginosa infection. | 1997 | Am. J. Respir. Crit. Care Med. | pmid:9001333 |
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Choi GE et al. | Macrolide treatment for Mycobacterium abscessus and Mycobacterium massiliense infection and inducible resistance. | 2012 | Am. J. Respir. Crit. Care Med. | pmid:22878281 |
Schluger NW | Treatment of pulmonary Mycobacterium avium complex infections: do drug levels matter? | 2012 | Am. J. Respir. Crit. Care Med. | pmid:23071188 |
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van Ingen J et al. | The pharmacokinetics and pharmacodynamics of pulmonary Mycobacterium avium complex disease treatment. | 2012 | Am. J. Respir. Crit. Care Med. | pmid:22744719 |
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Semret M et al. | Mycobacterium ulcerans infection (Buruli ulcer): first reported case in a traveler. | 1999 | Am. J. Trop. Med. Hyg. | pmid:10586895 |
Morovic M | Q Fever pneumonia: are clarithromycin and moxifloxacin alternative treatments only? | 2005 | Am. J. Trop. Med. Hyg. | pmid:16282309 |
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Fajardo TT et al. | A clinical trial of ethionamide and prothionamide for treatment of lepromatous leprosy. | 2006 | Am. J. Trop. Med. Hyg. | pmid:16525107 |
Miftahussurur M et al. | Clarithromycin-Based Triple Therapy is Still Useful as an Initial Treatment for Infection in the Dominican Republic. | 2017 | Am. J. Trop. Med. Hyg. | pmid:28193745 |
Womble AY et al. | Pharmacokinetics of clarithromycin and concentrations in body fluids and bronchoalveolar cells of foals. | 2006 | Am. J. Vet. Res. | pmid:17014316 |
Marini RP et al. | Ranitidine bismuth citrate and clarithromycin, alone or in combination, for eradication of Helicobacter mustelae infection in ferrets. | 1999 | Am. J. Vet. Res. | pmid:10791942 |
Heifets LB et al. | Clarithromycin minimal inhibitory and bactericidal concentrations against Mycobacterium avium. | 1992 | Am. Rev. Respir. Dis. | pmid:1532486 |
Ruf B et al. | Acquired resistance of MAI to clarithromycin. | 1992 | Am. Rev. Respir. Dis. | pmid:1533999 |
Dautzenberg B et al. | Activity of clarithromycin against Mycobacterium avium infection in patients with the acquired immune deficiency syndrome. A controlled clinical trial. | 1991 | Am. Rev. Respir. Dis. | pmid:1832527 |
Lage R et al. | Mycobacterium chelonae cutaneous infection in a patient with mixed connective tissue disease. | An Bras Dermatol | pmid:25672306 | |
Moreira C et al. | Symmetrical drug-related intertriginous and flexural exanthema induced by clarithromycin. | An Bras Dermatol | pmid:28954125 | |
Bujanda L et al. | [Comparative study of the eradication of Helicobacter pylori: ranitidine bismuth citrate versus omeprazole plus two antibiotics for seven days]. | 2001 | An Med Interna | pmid:11534420 |
Gómez Cubillos C et al. | [Can macrolide treatment delay the diagnosis of tuberculosis?]. | 1999 | An Med Interna | pmid:10481348 |
DÃaz GarcÃa MJ et al. | [EKG changes in a patient with respiratory infection]. | 2005 | An Med Interna | pmid:16302306 |
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Alcalá Minagorre PJ et al. | [Rickettsia slovaca infection alter a tick bite]. | 2006 | An Pediatr (Barc) | pmid:17020735 |
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Sanz Santaeufemia FJ et al. | [Usefulness of chemotherapy associated with surgery in the management of nontuberculous mycobacterial adenitis]. | 2005 | An Pediatr (Barc) | pmid:15737291 |
Utük O et al. | [The effects of clarithromycin treatment on cardiac events in acute coronary syndrome patients]. | 2004 | Anadolu Kardiyol Derg | pmid:15355822 |
Marina M et al. | Antimicrobial susceptibility of anaerobic bacteria in Bulgaria. | 2009 | Anaerobe | pmid:19292999 |
Boyanova L et al. | Anaerobic microbiology in 198 cases of pleural empyema: a Bulgarian study. | 2004 | Anaerobe | pmid:16701526 |
Senhorinho GN et al. | Occurrence and antimicrobial susceptibility of Porphyromonas spp. and Fusobacterium spp. in dogs with and without periodontitis. | 2012 | Anaerobe | pmid:22609780 |
Dong SY et al. | Electrochemical studies of the interaction of clarithromycin with bovine serum albumin. | 2008 | Anal Sci | pmid:18781017 |
Galvidis I et al. | Group determination of 14-membered macrolide antibiotics and azithromycin using antibodies against common epitopes. | 2015 | Anal. Biochem. | pmid:25256165 |