clarithromycin

clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.

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Introduction

To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with clarithromycin?

clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with clarithromycin

MeSH term MeSH ID Detail
Sacroiliitis D058566 1 associated lipids
Chlamydial Pneumonia D061387 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with clarithromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with clarithromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with clarithromycin?


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Function Cross reference Weighted score Related literatures

What lipids are associated with clarithromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with clarithromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with clarithromycin?

Mouse Model

Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).

Knock-out

Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).

Experimental Pneumococcal Meningitis

Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with clarithromycin

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Authors Title Published Journal PubMed Link
Tietz A et al. Fulminant liver failure associated with clarithromycin. 2003 Ann Pharmacother pmid:12503933
Grunden JW and Fisher KA Lovastatin-induced rhabdomyolysis possibly associated with clarithromycin and azithromycin. 1997 Jul-Aug Ann Pharmacother pmid:9220046
Fraser LA et al. Calcium channel blocker-clarithromycin drug interaction did not increase the risk of nonvertebral fracture: a population-based study. 2015 Ann Pharmacother pmid:25429094
Gerónimo-Pardo M et al. Clarithromycin-nifedipine interaction as possible cause of vasodilatory shock. 2005 Ann Pharmacother pmid:15703161
Gooderham MJ et al. Concomitant digoxin toxicity and warfarin interaction in a patient receiving clarithromycin. 1999 Jul-Aug Ann Pharmacother pmid:10466907
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Marra F et al. A comparison of antibiotic use in children between Canada and Denmark. 2007 Ann Pharmacother pmid:17374628
Sipe BE et al. Rhabdomyolysis causing AV blockade due to possible atorvastatin, esomeprazole, and clarithromycin interaction. 2003 Ann Pharmacother pmid:12773066
De Bruin ML et al. Use of cisapride with contraindicated drugs in The Netherlands. 2002 Ann Pharmacother pmid:11847959
Courter JD et al. Increased clinical failures when treating acute otitis media with macrolides: a meta-analysis. 2010 Ann Pharmacother pmid:20150506
Pollak PT et al. Delirium probably induced by clarithromycin in a patient receiving fluoxetine. 1995 Ann Pharmacother pmid:7655131
Greco S et al. Glossitis, stomatitis, and black tongue with lansoprazole plus clarithromycin and other antibiotics. 1997 Ann Pharmacother pmid:9416400
Rollot F et al. Acute colchicine intoxication during clarithromycin administration. 2004 Ann Pharmacother pmid:15494379
Ibrahim RB et al. Tacrolimus-clarithromycin interaction in a patient receiving bone marrow transplantation. 2002 Ann Pharmacother pmid:12452763
Tseng AL and Walmsley SL Rifabutin-associated uveitis. 1995 Ann Pharmacother pmid:8573961
Kahri AJ et al. Rhabdomyolysis associated with concomitant use of simvastatin and clarithromycin. 2004 Ann Pharmacother pmid:14966253
Burgess DS et al. A time-kill evaluation of clarithromycin and azithromycin against two extracellular pathogens and the development of resistance. 1999 Ann Pharmacother pmid:10630825
González Carro P et al. Acute pancreatitis and modified-release clarithromycin. 2004 Ann Pharmacother pmid:14755067
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Giannattasio A et al. Steroid therapy for a case of severe drug-induced cholestasis. 2006 Ann Pharmacother pmid:16720710
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Gray VS Syncopal episodes associated with cisapride and concurrent drugs. 1998 Ann Pharmacother pmid:9640482
Nawarskas JJ et al. Digoxin toxicity secondary to clarithromycin therapy. 1997 Jul-Aug Ann Pharmacother pmid:9220047
Recker MW and Kier KL Potential interaction between clarithromycin and warfarin. 1997 Ann Pharmacother pmid:9296238
Laberge P and Martineau P Clarithromycin-induced digoxin intoxication. 1997 Ann Pharmacother pmid:9296239
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Issa H et al. Bleeding duodenal ulcer after Roux-en-Y gastric bypass surgery: the value of laparoscopic gastroduodenoscopy. Ann Saudi Med pmid:20103961
Varghese B et al. First case report of chronic pulmonary lung disease caused by Mycobacterium abscessus in two immunocompetent patients in Saudi Arabia. Ann Saudi Med pmid:22588446
Moosavian M et al. Rapid detection of clarithromycin-resistant Helicobacter pylori in patients with dyspepsia by fluorescent in situ hybridization (FISH) compared with the E-test. 2007 Mar-Apr Ann Saudi Med pmid:17356313
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Wali S Mycobacterium chelonae empyema with bronchopleural fistula in an immunocompetent patient. 2009 Ann Thorac Med pmid:19881169
Tanih NF et al. Characterisation of the genes encoding resistance to metronidazole (rdxA and frxA) and clarithromycin (the 23S-rRNA genes) in South African isolates of Helicobacter pylori. 2011 Ann Trop Med Parasitol pmid:21801504
Tan HH et al. Cutaneous Mycobacterium haemophilum infections in immunocompromised patients in a dermatology clinic in Singapore. 2004 Ann. Acad. Med. Singap. pmid:15329772
Lee HY et al. Unresolving furunculosis in a diabetic patient: cutaneous Mycobacterium abscessus infection. 2009 Ann. Acad. Med. Singap. pmid:19271048
Amayasu H et al. Clarithromycin suppresses bronchial hyperresponsiveness associated with eosinophilic inflammation in patients with asthma. 2000 Ann. Allergy Asthma Immunol. pmid:10875487
Dubini M et al. Multiple drug allergy: A case of anaphylaxis to levofloxacin but tolerance to ciprofloxacin. 2016 Ann. Allergy Asthma Immunol. pmid:27009438
Fonseca-Aten M et al. Effect of clarithromycin on cytokines and chemokines in children with an acute exacerbation of recurrent wheezing: a double-blind, randomized, placebo-controlled trial. 2006 Ann. Allergy Asthma Immunol. pmid:17069099
Hahn DL et al. Evidence for Chlamydia pneumoniae infection in steroid-dependent asthma. 1998 Ann. Allergy Asthma Immunol. pmid:9475566
Swamy N et al. Successful clarithromycin desensitization in a multiple macrolide-allergic patient. 2010 Ann. Allergy Asthma Immunol. pmid:21130389
McCarty JM and Pierce PF Five days of cefprozil versus 10 days of clarithromycin in the treatment of an acute exacerbation of chronic bronchitis. 2001 Ann. Allergy Asthma Immunol. pmid:11686426
Spahn JD et al. Clarithromycin potentiates glucocorticoid responsiveness in patients with asthma: results of a pilot study. 2001 Ann. Allergy Asthma Immunol. pmid:11770698
Mori F et al. Sensitivity and specificity of skin tests in the diagnosis of clarithromycin allergy. 2010 Ann. Allergy Asthma Immunol. pmid:20486332
Morisset J et al. A case of difficult-to-treat eosinophilic asthma controlled with clarithromycin. 2012 Ann. Allergy Asthma Immunol. pmid:22727169
Randhawa I and Klaustermeyer WB Oral corticosteroid-dependent asthma: a 30-year review. 2007 Ann. Allergy Asthma Immunol. pmid:17941275
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Akram FE et al. A combination of silver nanoparticles and visible blue light enhances the antibacterial efficacy of ineffective antibiotics against methicillin-resistant Staphylococcus aureus (MRSA). 2016 Ann. Clin. Microbiol. Antimicrob. pmid:27530257
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Bolland MJ et al. Osteomalacia in an HIV-infected man receiving rifabutin, a cytochrome P450 enzyme inducer: a case report. 2008 Ann. Clin. Microbiol. Antimicrob. pmid:18226256
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