MeSH term | MeSH ID | Detail |
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Abortion, Spontaneous | D000022 | 12 associated lipids |
Abnormalities, Drug-Induced | D000014 | 10 associated lipids |
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with clarithromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Altintas E et al. | Maastricht II treatment scheme and efficacy of different proton pump inhibitors in eradicating Helicobacter pylori. | 2004 | World J. Gastroenterol. | pmid:15162544 |
Cosme A et al. | Antimicrobial susceptibility testing before first-line treatment for infection in patients with dual or triple antibiotic resistance. | 2017 | World J. Gastroenterol. | pmid:28566898 |
Lai YC et al. | Density of Helicobacter pylori may affect the efficacy of eradication therapy and ulcer healing in patients with active duodenal ulcers. | 2003 | World J. Gastroenterol. | pmid:12854158 |
Si JM et al. | Quality of gastric ulcer healing evaluated by endoscopic ultrasonography. | 2005 | World J. Gastroenterol. | pmid:15948255 |
Hagiwara T et al. | Improvement in symptoms after H2-receptor antagonist-based therapy for eradication of H pylori infection. | 2007 | World J. Gastroenterol. | pmid:17657838 |
Sanches BS et al. | Detection of Helicobacter pylori resistance to clarithromycin and fluoroquinolones in Brazil: A national survey. | 2016 | World J. Gastroenterol. | pmid:27672279 |
Gumurdulu Y et al. | Low eradication rate of Helicobacter pylori with triple 7-14 days and quadriple therapy in Turkey. | 2004 | World J. Gastroenterol. | pmid:14991935 |
Ahmad N et al. | Characterization of clarithromycin resistance in Malaysian isolates of Helicobacter pylori. | 2009 | World J. Gastroenterol. | pmid:19575497 |
Guo CY et al. | Clinical evaluation of four one-week triple therapy regimens in eradicating Helicobacter pylori infection. | 2004 | World J. Gastroenterol. | pmid:14991953 |
Luo XF et al. | Establishment of a nested-ASP-PCR method to determine the clarithromycin resistance of Helicobacter pylori. | 2016 | World J. Gastroenterol. | pmid:27433095 |
Trifan A et al. | Pseudomembranous colitis associated with a triple therapy for Helicobacter pylori eradication. | 2013 | World J. Gastroenterol. | pmid:24259981 |
Sun QJ et al. | Resistance of Helicobacter pylori to antibiotics from 2000 to 2009 in Shanghai. | 2010 | World J. Gastroenterol. | pmid:20976850 |
Chuah SK et al. | A new look at anti-Helicobacter pylori therapy. | 2011 | World J. Gastroenterol. | pmid:22046084 |
Chen SJ et al. | Effect of H pylori infection and its eradication on hyperammo-nemia and hepatic encephalopathy in cirrhotic patients. | 2008 | World J. Gastroenterol. | pmid:18350632 |
Abadi ATB | Resistance to clarithromycin and gastroenterologist's persistence roles in nomination for Helicobacter pylori as high priority pathogen by World Health Organization. | 2017 | World J. Gastroenterol. | pmid:29085187 |
Lai YC et al. | Pre-treatment urea breath test results predict the efficacy of Helicobacter pylori eradication therapy in patients with active duodenal ulcers. | 2004 | World J. Gastroenterol. | pmid:15052680 |
Ji F et al. | Effect of drug treatment on hyperplastic gastric polyps infected with Helicobacter pylori: a randomized, controlled trial. | 2006 | World J. Gastroenterol. | pmid:16586550 |
Molina-Infante J and Gisbert JP | Optimizing clarithromycin-containing therapy for Helicobacter pylori in the era of antibiotic resistance. | 2014 | World J. Gastroenterol. | pmid:25132750 |
Sereni G et al. | Efficacy of a therapeutic strategy for eradication of Helicobacter pylori infection. | 2012 | World J. Gastroenterol. | pmid:22969227 |
Aydemir S et al. | Helicobacter pylori infection in hemodialysis patients: susceptibility to amoxicillin and clarithromycin. | 2005 | World J. Gastroenterol. | pmid:15682477 |
O'Morain C | Role of Helicobacter pylori in functional dyspepsia. | 2006 | World J. Gastroenterol. | pmid:16718752 |
Shimbo I et al. | Effect of Clostridium butyricum on fecal flora in Helicobacter pylori eradication therapy. | 2005 | World J. Gastroenterol. | pmid:16437727 |
Sun WH et al. | Efficacy of omeprazole and amoxicillin with either clarithromycin or metronidazole on eradication of Helicobacter pylori in Chinese peptic ulcer patients. | 2005 | World J. Gastroenterol. | pmid:15832421 |
Wu IT et al. | Five-year sequential changes in secondary antibiotic resistance of Helicobacter pylori in Taiwan. | 2015 | World J. Gastroenterol. | pmid:26457027 |
Yilmaz O and Demiray E | Clinical role and importance of fluorescence in situ hybridization method in diagnosis of H pylori infection and determination of clarithromycin resistance in H pylori eradication therapy. | 2007 | World J. Gastroenterol. | pmid:17278188 |
Mohammadi M et al. | Helicobacter pylori antibiotic resistance in Iran. | 2005 | World J. Gastroenterol. | pmid:16273615 |
Nishida T et al. | Comparative study of esomeprazole and lansoprazole in triple therapy for eradication of Helicobacter pylori in Japan. | 2014 | World J. Gastroenterol. | pmid:24764674 |
Sakurai K et al. | Comparative study: Vonoprazan and proton pump inhibitors in eradication therapy. | 2017 | World J. Gastroenterol. | pmid:28216974 |
Onyekwere CA et al. | Rabeprazole, clarithromycin, and amoxicillin Helicobacter pylori eradication therapy: report of an efficacy study. | 2014 | World J. Gastroenterol. | pmid:24707145 |
Wu JY et al. | Detection of genotypic clarithromycin-resistant Helicobacter pylori by string tests. | 2014 | World J. Gastroenterol. | pmid:24695835 |
Mabe K et al. | Does Helicobacter pylori eradication therapy for peptic ulcer prevent gastric cancer? | 2009 | World J. Gastroenterol. | pmid:19750572 |
Riquelme A et al. | Optimal length of triple therapy for H pylori eradication in a population with high prevalence of infection in Chile. | 2007 | World J. Gastroenterol. | pmid:17589948 |
Ersoy O et al. | H pylori infection in patients with Behcet's disease. | 2007 | World J. Gastroenterol. | pmid:17589951 |
Grande M et al. | Helicobacter pylori and gastroesophageal reflux disease. | 2008 | World J Surg Oncol | pmid:18601740 |
Cavanna L et al. | High grade B-cell gastric lymphoma with complete pathologic remission after eradication of Helicobacter pylori infection: report of a case and review of the literature. | 2008 | World J Surg Oncol | pmid:18353178 |
Whittemore KR and Cohen M | Imaging and review of a large pre-auricular pilomatrixoma in a child. | 2012 | World J Radiol | pmid:22761984 |
Yanai A et al. | Non-bismuth quadruple therapy for first-line Helicobacter pylori eradication: A randomized study in Japan. | 2012 | World J Gastrointest Pharmacol Ther | pmid:22408744 |
Francesco VD et al. | Mechanisms of Helicobacter pylori antibiotic resistance: An updated appraisal. | 2011 | World J Gastrointest Pathophysiol | pmid:21860834 |
Bago P et al. | High eradication rate of H. pylori with moxifloxacin-based treatment: a randomized controlled trial. | 2007 | Wien. Klin. Wochenschr. | pmid:17634896 |
Bago J et al. | The impact of primary antibiotic resistance on the efficacy of ranitidine bismuth citrate- vs. omeprazole-based one-week triple therapies in H. pylori eradication--a randomised controlled trial. | 2002 | Wien. Klin. Wochenschr. | pmid:12422579 |
Bago J et al. | Comparison of the efficacy of 250 mg and 500 mg clarithromycin used with lansoprazole and amoxicillin in eradication regimens for Helicobacter pylori infection. | 2004 | Wien. Klin. Wochenschr. | pmid:15379146 |
Vcev A et al. | Amoxycillin, clarithromycin and either sucralfate or pantoprazole for eradication of Helicobacter pylori in duodenal ulcer (a randomized controlled trial). | 2001 | Wien. Klin. Wochenschr. | pmid:11802510 |
Li Y et al. | Advantages of Moxifloxacin and Levofloxacin-based triple therapy for second-line treatments of persistent Helicobacter pylori infection: a meta analysis. | 2010 | Wien. Klin. Wochenschr. | pmid:20628905 |
NiziÄ T et al. | Solitary erythema migrans in children: comparison of treatment with clarithromycin and amoxicillin. | 2012 | Wien. Klin. Wochenschr. | pmid:22760494 |
Kurz H and Göpfrich H | [Epidemiology and morbidity of mycoplasma as causative agent for community-acquired pneumonia in hospitalized children in a Community Hospital in Vienna]. | 2011 | Wien Med Wochenschr | pmid:20963506 |
Kardas P and Muras M | [A blinded comparison of palatability of 13 common pediatric antibiotic suspensions]. | 2005 | Wiad. Lek. | pmid:15991547 |
Gościmski A et al. | [Microflora of gastric juice in patients after eradication of Helicobacter pylori and treatment with a proton pump inhibitor]. | 2002 | Wiad. Lek. | pmid:12043311 |
Dhawan VK et al. | Vancomycin-resistant enterococcal colonization in nonhospitalized HIV-infected patients. | 1998 | West. J. Med. | pmid:9830355 |
Kanatani MS and Guglielmo BJ | The new macrolides. Azithromycin and clarithromycin. | 1994 | West. J. Med. | pmid:8128699 |
Feng X et al. | [Interaction between biofilm formed by Pseudomonas aeruginosa and antibacterial agents]. | 2000 | Wei Sheng Wu Xue Bao | pmid:12548947 |