| MeSH term | MeSH ID | Detail |
|---|---|---|
| Cytomegalovirus Retinitis | D017726 | 2 associated lipids |
| Still's Disease, Adult-Onset | D016706 | 2 associated lipids |
| Leprosy, Borderline | D015439 | 3 associated lipids |
| Discitis | D015299 | 2 associated lipids |
| Cardiovascular Abnormalities | D018376 | 2 associated lipids |
| Pneumonia, Mycoplasma | D011019 | 6 associated lipids |
| Desulfovibrionaceae Infections | D045824 | 5 associated lipids |
| Periodontal Abscess | D010508 | 2 associated lipids |
| Sexually Transmitted Diseases, Bacterial | D015231 | 5 associated lipids |
| Conjunctivitis, Bacterial | D003234 | 3 associated lipids |
clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with clarithromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (2)
- J. Antimicrob. Chemother. (1)
- Clin. Diagn. Lab. Immunol. (1)
- Others (2)
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Soepandi P et al. | The pattern of micro-organisms and the efficacy of new macrolide in acute lower respiratory tract infections. | 1998 | Respirology | pmid:9692520 |
| Rosário M et al. | [Profile of the resistance to macrolides and imidazoles of Helicobacter pylori in a sample of the Portuguese population]. | 1998 | Acta Med Port | pmid:10192979 |
| Highleyman L | FDA issues Hismanal warning. Food and Drug Administration. | 1998 | BETA | pmid:11365263 |
| Elliott RL et al. | Anhydrolide macrolides. 1. Synthesis and antibacterial activity of 2,3-anhydro-6-O-methyl 11,12-carbamate erythromycin A analogues. | 1998 | J. Med. Chem. | pmid:9572890 |
| Griesgraber G et al. | Anhydrolide macrolides. 2. Synthesis and antibacterial activity of 2,3-anhydro-6-O-methyl 11,12-carbazate erythromycin A analogues. | 1998 | J. Med. Chem. | pmid:9572891 |
| Al-Sibai MB et al. | Ocular penetration of oral clarithromycin in humans. | 1998 | J Ocul Pharmacol Ther | pmid:9867340 |
| Huang WH et al. | New one-week, low-dose triple therapy for the treatment of duodenal ulcer with Helicobacter pylori infection. | 1998 | Zhonghua Yi Xue Za Zhi (Taipei) | pmid:9745160 |
| Sádaba B et al. | Concurrent clarithromycin and cyclosporin A treatment. | 1998 | J. Antimicrob. Chemother. | pmid:9786481 |
| Finkenbine RD and Frye MD | Case of psychosis due to prednisone-clarithromycin interaction. | 1998 | Gen Hosp Psychiatry | pmid:9788033 |
| Borody TJ | Helicobacter pylori eradication failure--'salvage' therapies needed. | 1998 | Ital J Gastroenterol Hepatol | pmid:9789131 |
| Coudron PE and Stratton CW | The bactericidal activity of clarithromycin versus ampicillin alone and in combination with omeprazole and/or bismuth against clarithromycin-susceptible and clarithromycin-resistant strains of Helicobacter pylori. | 1998 | Diagn. Microbiol. Infect. Dis. | pmid:9791756 |
| Niang M et al. | [Painful nodular lesions]. | 1998 | Rev Med Interne | pmid:9793156 |
| Saika T et al. | [A mechanism of clarithromycin resistance in Helicobacter pylori]. | 1998 | Kansenshogaku Zasshi | pmid:9796191 |
| Abouesh A and Hobbs WR | Clarithromycin-induced mania. | 1998 | Am J Psychiatry | pmid:9812131 |
| Gikas A et al. | In vitro susceptibility of Coxiella burnetii to trovafloxacin in comparison with susceptibilities to pefloxacin, ciprofloxacin, ofloxacin, doxycycline, and clarithromycin. | 1998 | Antimicrob. Agents Chemother. | pmid:9756789 |
| Hoppe JE and Bryskier A | In vitro susceptibilities of Bordetella pertussis and Bordetella parapertussis to two ketolides (HMR 3004 and HMR 3647), four macrolides (azithromycin, clarithromycin, erythromycin A, and roxithromycin), and two ansamycins (rifampin and rifapentine). | 1998 | Antimicrob. Agents Chemother. | pmid:9559823 |
| Lamouliatte H et al. | Dual therapy using a double dose of lansoprazole with amoxicillin versus triple therapy using a double dose of lansoprazole, amoxicillin, and clarithromycin to eradicate Helicobacter pylori infection: results of a prospective randomized open study. | 1998 | Am. J. Gastroenterol. | pmid:9732938 |
| Coudron PE and Stratton CW | In-vitro evaluation of nitrofurantoin as an alternative agent for metronidazole in combination antimicrobial therapy against Helicobacter pylori. | 1998 | J. Antimicrob. Chemother. | pmid:9848452 |
| Cadwgan AM et al. | Neisseria meningitidis W135 pneumonia with sepicaemia in a nonogenarian. | 1998 | Scott Med J | pmid:9854302 |
| Shimoyama T et al. | Healing of cimetidine-resistant Ménétrier's disease by eradication of Helicobacter pylori infection. | 1998 | J. Clin. Gastroenterol. | pmid:9855268 |
| Siu LK et al. | Evaluation of a selective transport medium for gastric biopsy specimens to be cultured for Helicobacter pylori. | 1998 | J. Clin. Microbiol. | pmid:9738066 |
| Cestari R | Ranitidine bismuth citrate (RBC) based triple therapy for 7 days is more effective than RBC plus clarithromycin for 14 days in dyspeptic patients with Helicobacter pylori infection. H. Pylori Lombardy Group. | 1998 | Aliment. Pharmacol. Ther. | pmid:9798804 |
| Spadaccini A et al. | Triple regimens using lansoprazole or ranitidine bismuth citrate for Helicobacter pylori eradication. | 1998 | Aliment. Pharmacol. Ther. | pmid:9798805 |
| Sevin E et al. | Co-detection of Helicobacter pylori and of its resistance to clarithromycin by PCR. | 1998 | FEMS Microbiol. Lett. | pmid:9742711 |
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| Hiratsuka T et al. | [Severe bronchorrhea accompanying alveolar cell carcinoma: treatment with clarithromycin and inhaled beclomethasone]. | 1998 | Nihon Kokyuki Gakkai Zasshi | pmid:9742869 |
| Hynes B | Contact granulomas. | 1998 | J Otolaryngol | pmid:9800633 |
| Fischer BP et al. | [Tsutsugamushi fever. Rare rickettsiosis after a stay in the Philippines]. | 1998 | Dtsch. Med. Wochenschr. | pmid:9615696 |
| Torresani C | Clarithromycin: a new perspective in rosacea treatment. | 1998 | Int. J. Dermatol. | pmid:9620480 |
| Kashuba AD and Amsden GW | Bronchopulmonary pharmacokinetics of clarithromycin and azithromycin. | 1998 | Antimicrob. Agents Chemother. | pmid:9527816 |
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| Einarson A et al. | A prospective controlled multicentre study of clarithromycin in pregnancy. | 1998 | Am J Perinatol | pmid:9890248 |
| Tsuneoka H et al. | [Sensitivity of Helicobacter pylori to amoxicillin and clarythromycin with special reference to eradication therapy]. | 1998 | Kansenshogaku Zasshi | pmid:9621560 |
| Amsden GW et al. | Oral cimetidine prolongs clarithromycin absorption. | 1998 | Antimicrob. Agents Chemother. | pmid:9660986 |
| Spinzi GC et al. | Comparison of omeprazole and lansoprazole in short-term triple therapy for Helicobacter pylori infection. | 1998 | Aliment. Pharmacol. Ther. | pmid:9663722 |
| Bazzoli F et al. | Evaluation of short-term low-dose triple therapy for the eradication of Helicobacter pylori by factorial design in a randomized, double-blind, controlled study. | 1998 | Aliment. Pharmacol. Ther. | pmid:9663723 |
| Pozzato P et al. | Ranitidine bismuth citrate plus clarithromycin 7-day regimen is effective in eradicating Helicobacter pylori in patients with duodenal ulcer. | 1998 | Aliment. Pharmacol. Ther. | pmid:9663724 |
| Butt AA | Cervical adenitis due to Mycobacterium fortuitum in patients with acquired immunodeficiency syndrome. | 1998 | Am. J. Med. Sci. | pmid:9427575 |
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| Dal Bo' N et al. | Low dose of clarithromycin in triple therapy for the eradication of Helicobacter pylori: one or two weeks? | 1998 | J. Gastroenterol. Hepatol. | pmid:9570242 |
| O'Connor HJ et al. | Lansoprazole triple therapy for Helicobacter pylori--is 5 days enough? | 1998 | Aliment. Pharmacol. Ther. | pmid:9570262 |
| Scott BB | Bismuth-containing single-antibiotic 1-week triple therapy for Helicobacter pylori eradication. | 1998 | Aliment. Pharmacol. Ther. | pmid:9570263 |
| Jarboe E et al. | Evaluation of a disk diffusion method for determining susceptibility of Mycobacterium avium complex to clarithromycin. | 1998 | Diagn. Microbiol. Infect. Dis. | pmid:9572027 |
| Lasko B et al. | Efficacy and safety of oral levofloxacin compared with clarithromycin in the treatment of acute sinusitis in adults: a multicentre, double-blind, randomized study. The Canadian Sinusitis Study Group. | 1998 | J. Int. Med. Res. | pmid:10399110 |
| Valsecchi R and Pigatto P | Chronic urticaria and Helicobacter pylori. | 1998 | Acta Derm. Venereol. | pmid:9833044 |
| van Haarst AD et al. | The influence of cisapride and clarithromycin on QT intervals in healthy volunteers. | 1998 | Clin. Pharmacol. Ther. | pmid:9834046 |
| Xia HH et al. | Metronidazole- and clarithromycin-resistant Helicobacter pylori in dyspeptic patients in western Sydney as determined by testing multiple isolates from different gastric sites. | 1998 | J. Gastroenterol. Hepatol. | pmid:9835322 |
| Borody TJ et al. | Eradication therapies for Helicobacter pylori. | 1998 | J. Gastroenterol. | pmid:9840019 |
| Moayyedi P et al. | Relevance of antibiotic sensitivities in predicting failure of omeprazole, clarithromycin, and tinidazole to eradicate Helicobacter pylori. | 1998 | J. Gastroenterol. | pmid:9840021 |
| Ohkusa T et al. | Disappearance of hyperplastic polyps in the stomach after eradication of Helicobacter pylori. A randomized, clinical trial. | 1998 | Ann. Intern. Med. | pmid:9841603 |
| Kato S et al. | Safety and efficacy of one-week triple therapy for eradicating Helicobacter pylori in children. | 1998 | Helicobacter | pmid:9844069 |
| Gisbert JP et al. | [Omeprazole plus 2 antibiotics for the eradication of H. pylori, are 5 days of treatment sufficient?]. | 1998 | Rev Clin Esp | pmid:9844453 |
| Gisbert JP et al. | [Role of pantoprazole in the eradicating treatment of Helicobacter pylori]. | 1998 | Rev Clin Esp | pmid:9844458 |
| Gudjonsson H et al. | High Helicobacter pylori eradication rate with a 1-week regimen containing ranitidine bismuth citrate. | 1998 | Aliment. Pharmacol. Ther. | pmid:9845401 |
| Iino Y et al. | [Immunohistochemical study of the paranasal sinus mucosa of patients being treated with macrolide antibiotics--effects of antigen-presenting cells on the expression of a costimulator]. | 1998 | Jpn J Antibiot | pmid:9597477 |
| Salgado CG et al. | [Study on the effects of macrolide antibiotics on the expression of B7-1, B7-2, and CD40 on epidermal Langerhans cells]. | 1998 | Jpn J Antibiot | pmid:9597478 |
| Isono K et al. | [Effects of macrolide antibiotics on neutrophil infiltration into the airway mucosa and ICAM-1 expression]. | 1998 | Jpn J Antibiot | pmid:9597480 |
| Enomoto F et al. | [Changes in adhesion molecule expressions in neutrophils caused by new macrolide administration]. | 1998 | Jpn J Antibiot | pmid:9597482 |
| Ieshiro R et al. | [Effect of clarithromycin in extending the life expectancy of patients with non-small-cell lung cancer--the second report]. | 1998 | Jpn J Antibiot | pmid:9597484 |
| Sakamoto M et al. | [Efficacy of clarithromycin (CAM) in patients with inoperable non-small-cell lung cancer]. | 1998 | Jpn J Antibiot | pmid:9597485 |
| Teramoto S et al. | [Effect of clarithromycin administration on interferon-gamma and interleukin 12 mRNA expression in the tumor tissue of non-small-cell lung cancer]. | 1998 | Jpn J Antibiot | pmid:9597486 |
| Ueta K et al. | [Evaluation of BRM (biological response modifier) action of clarithromycin (CAM)--effect on cytokine expression in a mouse lung cancer model]. | 1998 | Jpn J Antibiot | pmid:9597487 |
| Kokubo Y et al. | [Effect of clarithromycin on experimental pulmonary metastasis]. | 1998 | Jpn J Antibiot | pmid:9597488 |
| Hocqueloux L et al. | Pulmonary Mycobacterium avium complex disease without dissemination in HIV-infected patients. | 1998 | Chest | pmid:9498982 |
| Malfertheiner P and Blum AL | [Helicobacter pylori infection and ulcer]. | 1998 | Chirurg | pmid:9576033 |
| Yano S et al. | [Significance of therapeutic efficacy of clarithromycin in a model for human lung cancer metastasis and a mouse tumor system]. | 1998 | Jpn J Antibiot | pmid:9597491 |
| Lee KL et al. | QT prolongation and Torsades de Pointes associated with clarithromycin. | 1998 | Am. J. Med. | pmid:9576415 |
| Sasa K et al. | [Antineoplastic therapeutic effect of clarithromycin in rats]. | 1998 | Jpn J Antibiot | pmid:9597492 |
| Schwartz H et al. | Triple versus dual therapy for eradicating Helicobacter pylori and preventing ulcer recurrence: a randomized, double-blind, multicenter study of lansoprazole, clarithromycin, and/or amoxicillin in different dosing regimens. | 1998 | Am. J. Gastroenterol. | pmid:9576452 |
| Felmingham D et al. | Antimicrobial susceptibility of community-acquired lower respiratory tract bacterial pathogens isolated in the UK during the 1995-1996 cold season. | 1998 | J. Antimicrob. Chemother. | pmid:9578171 |
| Tatsis G et al. | Efficacy and tolerance of roxithromycin versus clarithromycin in the treatment of lower respiratory tract infections. | 1998 | J. Antimicrob. Chemother. | pmid:9579716 |
| Perng CL et al. | One-week triple therapy with lansoprazole, clarithromycin, and metronidazole to cure Helicobacter pylori infection in peptic ulcer disease in Korea. | 1998 | Dig. Dis. Sci. | pmid:9539638 |
| Goldstein EJ et al. | Activities of HMR 3004 (RU 64004) and HMR 3647 (RU 66647) compared to those of erythromycin, azithromycin, clarithromycin, roxithromycin, and eight other antimicrobial agents against unusual aerobic and anaerobic human and animal bite pathogens isolated from skin and soft tissue infections in humans. | 1998 | Antimicrob. Agents Chemother. | pmid:9593139 |
| Scheen AJ | [Drug clinics. The drug of the month. Ranitidine bismuth citrate (Pylorid)]. | 1998 | Rev Med Liege | pmid:9555183 |
| Spangler SK et al. | Postantibiotic effect and postantibiotic sub-MIC effect of levofloxacin compared to those of ofloxacin, ciprofloxacin, erythromycin, azithromycin, and clarithromycin against 20 pneumococci. | 1998 | Antimicrob. Agents Chemother. | pmid:9593160 |
| Cheng KL et al. | Effect of grapefruit juice on clarithromycin pharmacokinetics. | 1998 | Antimicrob. Agents Chemother. | pmid:9559810 |
| Moayyedi P et al. | Relevance of antibiotic sensitivities in predicting failure of omeprazole, clarithromycin, and tinidazole to eradicate Helicobacter pylori. | 1998 | J. Gastroenterol. | pmid:9605943 |
| Gavura SR and Nusinowitz S | Leukocytoclastic vasculitis associated with clarithromycin. | 1998 | Ann Pharmacother | pmid:9606474 |
| Ramon PM et al. | [Uveitis, arthralgia and pseudo-jaundice in a HIV seronegative patient due to rifabutin]. | 1998 | Rev Mal Respir | pmid:9608993 |
| Lilley LL and Guanci R | A dangerous combination. | 1998 | Am J Nurs | pmid:9612423 |
| Sheu BS et al. | One-week proton pump inhibitor-based triple therapy eradicates residual Helicobacter pylori after failed dual therapy. | 1998 | J. Formos. Med. Assoc. | pmid:9585678 |
| Klein JO | Clarithromycin and azithromycin. | 1998 | Pediatr. Infect. Dis. J. | pmid:9655546 |
| Hasegawa M et al. | [In vitro activities of faropenem against clarithromycin resistance Helicobacter pylori isolates]. | 1998 | Kansenshogaku Zasshi | pmid:9585692 |
| Carr RA et al. | Steady-state pharmacokinetics and electrocardiographic pharmacodynamics of clarithromycin and loratadine after individual or concomitant administration. | 1998 | Antimicrob. Agents Chemother. | pmid:9593146 |
| Howden CW and Hunt RH | Treating Helicobacter pylori. | 1998 | Arch. Intern. Med. | pmid:9827792 |
| Bayoumi AM and Redelmeier DA | Preventing Mycobacterium avium complex in patients who are using protease inhibitors: a cost-effectiveness analysis. | 1998 | AIDS | pmid:9727572 |
| Alder JD et al. | Dynamics of clarithromycin and azithromycin efficacies against experimental Haemophilus influenzae pulmonary infection. | 1998 | Antimicrob. Agents Chemother. | pmid:9736568 |
| Takizawa H et al. | Erythromycin and clarithromycin attenuate cytokine-induced endothelin-1 expression in human bronchial epithelial cells. | 1998 | Eur. Respir. J. | pmid:9701415 |
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| Parente F et al. | Effects of Helicobacter pylori eradication on gastric function indices in functional dyspepsia. A prospective controlled study. | 1998 | Scand. J. Gastroenterol. | pmid:9648983 |
| Moshkowitz M et al. | One-week triple therapy with omeprazole, clarithromycin, and nitroimidazole for Helicobacter pylori infection in children and adolescents. | 1998 | Pediatrics | pmid:9651466 |
| Wiedermann BL | Macrolides: clarithromycin and azithromycin. | 1998 | Pediatr Rev | pmid:9654947 |
| Tanahashi T et al. | Analysis of the 13C-urea breath test for detection of Helicobacter pylori infection based on the kinetics of delta-13CO2 using laser spectroscopy. | 1998 | J. Gastroenterol. Hepatol. | pmid:9715426 |
| Hashimoto Y | [Eradication therapies for Helicobacter pylori]. | 1998 | Kansenshogaku Zasshi | pmid:9695480 |
| Wakasugi H et al. | Effect of clarithromycin on renal excretion of digoxin: interaction with P-glycoprotein. | 1998 | Clin. Pharmacol. Ther. | pmid:9695727 |
| Hsieh PF et al. | Molecular mechanisms of clarithromycin resistance in Helicobacter pylori. | 1998 | J. Formos. Med. Assoc. | pmid:9700240 |
| Ellenrieder V et al. | Influence of clarithromycin dosage on pantoprazole combined triple therapy for eradication of Helicobacter pylori. | 1998 | Aliment. Pharmacol. Ther. | pmid:9701524 |
| Burman WJ et al. | AIDS-related Mycobacterium kansasii infection with initial resistance to clarithromycin. | 1998 | Diagn. Microbiol. Infect. Dis. | pmid:9635911 |
| Nordt SP et al. | Clarithromycin induced digoxin toxicity. | 1998 | J Accid Emerg Med | pmid:9639187 |