| MeSH term | MeSH ID | Detail |
|---|---|---|
| Cytomegalovirus Retinitis | D017726 | 2 associated lipids |
| Still's Disease, Adult-Onset | D016706 | 2 associated lipids |
| Leprosy, Borderline | D015439 | 3 associated lipids |
| Discitis | D015299 | 2 associated lipids |
| Cardiovascular Abnormalities | D018376 | 2 associated lipids |
| Pneumonia, Mycoplasma | D011019 | 6 associated lipids |
| Desulfovibrionaceae Infections | D045824 | 5 associated lipids |
| Periodontal Abscess | D010508 | 2 associated lipids |
| Sexually Transmitted Diseases, Bacterial | D015231 | 5 associated lipids |
| Conjunctivitis, Bacterial | D003234 | 3 associated lipids |
clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with clarithromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| López-Brea M et al. | Evolution of resistance to metronidazole and clarithromycin in Helicobacter pylori clinical isolates from Spain. | 1997 | J. Antimicrob. Chemother. | pmid:9301996 |
| Versalovic J et al. | Point mutations in the 23S rRNA gene of Helicobacter pylori associated with different levels of clarithromycin resistance. | 1997 | J. Antimicrob. Chemother. | pmid:9301997 |
| Hoffman JS | Pharmacological therapy of Helicobacter pylori infection. | 1997 | Semin. Gastrointest. Dis. | pmid:9232728 |
| Sano M et al. | [A clinical study on combination therapy of antimicrobial agents for complicated urinary tract infection--with special reference to combination with clarithromycin]. | 1997 | Nippon Hinyokika Gakkai Zasshi | pmid:9234616 |
| Saluja A et al. | A surgical wound infection due to Mycobacterium chelonae successfully treated with clarithromycin. | 1997 | Dermatol Surg | pmid:9236871 |
| Gisbert JP et al. | [One-week treatment with omeprazole, clarithromycin and amoxicillin: high efficacy in the eradication of Helicobacter pylori and cicatrization of duodenal ulcer]. | 1997 | Med Clin (Barc) | pmid:9190436 |
| Damianos AJ and McGarrity TJ | Treatment strategies for Helicobacter pylori infection. | 1997 | Am Fam Physician | pmid:9191460 |
| Stephenson GA et al. | Solid-state investigations of erythromycin A dihydrate: structure, NMR spectroscopy, and hygroscopicity. | 1997 | J Pharm Sci | pmid:9383733 |
| Ebell MH et al. | Evaluation of the dyspeptic patient: a cost-utility study. | 1997 | J Fam Pract | pmid:9191627 |
| Griffith DE | Nontuberculous mycobacteria. | 1997 | Curr Opin Pulm Med | pmid:9193860 |
| Villanueva A et al. | Report on an outbreak of postinjection abscesses due to Mycobacterium abscessus, including management with surgery and clarithromycin therapy and comparison of strains by random amplified polymorphic DNA polymerase chain reaction. | 1997 | Clin. Infect. Dis. | pmid:9195073 |
| Gabl M et al. | Flexor tenosynovitis in the hand caused by Mycobacterium malmoense: a case report. | 1997 | J Hand Surg Am | pmid:9195437 |
| Rubin BK et al. | Effect of clarithromycin on nasal mucus properties in healthy subjects and in patients with purulent rhinitis. | 1997 | Am. J. Respir. Crit. Care Med. | pmid:9196110 |
| Spicer ST et al. | The mechanism of cyclosporine toxicity induced by clarithromycin. | 1997 | Br J Clin Pharmacol | pmid:9131953 |
| Guillemet C et al. | [Clarithromycin-digoxin: an unrecognized interaction in some patients]. | 1997 | Presse Med | pmid:9137381 |
| Rodrigues AD et al. | Oxidative metabolism of clarithromycin in the presence of human liver microsomes. Major role for the cytochrome P4503A (CYP3A) subfamily. | 1997 | Drug Metab. Dispos. | pmid:9152603 |
| Garrison MW et al. | Influence of pH on the antimicrobial activity of clarithromycin and 14-hydroxyclarithromycin against Haemophilus influenzae using an in vitro pharmacodynamic model. | 1997 | Diagn. Microbiol. Infect. Dis. | pmid:9154410 |
| Nightingale CH | Pharmacokinetics and pharmacodynamics of newer macrolides. | 1997 | Pediatr. Infect. Dis. J. | pmid:9109156 |
| Block SL | Causative pathogens, antibiotic resistance and therapeutic considerations in acute otitis media. | 1997 | Pediatr. Infect. Dis. J. | pmid:9109158 |
| Rodrigo Sáez L et al. | [The efficacy of using a short course of 6-day duration (OCA-6) in the treatment to eradicate Helicobacter pylori infection. Omeprazole, clarithromycin, amoxicillin]. | 1997 | Rev Esp Enferm Dig | pmid:9115827 |
| Reed PI and Johnston BJ | Treatment of Helicobacter pylori infection. | 1997 | Biomed. Pharmacother. | pmid:9084725 |
| Plemmons RM et al. | Osteomyelitis due to Mycobacterium haemophilum in a cardiac transplant patient: case report and analysis of interactions among clarithromycin, rifampin, and cyclosporine. | 1997 | Clin. Infect. Dis. | pmid:9142810 |
| Khan AA et al. | Activity of trovafloxacin in combination with other drugs for treatment of acute murine toxoplasmosis. | 1997 | Antimicrob. Agents Chemother. | pmid:9145840 |
| Fietta A et al. | Inhibition of intracellular growth of Staphylococcus aureus by exposure of infected human monocytes to clarithromycin and azithromycin. | 1997 | J Chemother | pmid:9106013 |
| Gan VN et al. | Penetration of clarithromycin into middle ear fluid of children with acute otitis media. | 1997 | Pediatr. Infect. Dis. J. | pmid:9002099 |
| Shortridge VD et al. | Molecular typing of Helicobacter pylori isolates from a multicenter U.S. clinical trial by ureC restriction fragment length polymorphism. | 1997 | J. Clin. Microbiol. | pmid:9003618 |
| Fischbach W et al. | Regression of immunoproliferative small intestinal disease after eradication of Helicobacter pylori. | 1997 | Lancet | pmid:8988128 |
| Walzer PD et al. | Clinically used antimicrobial drugs against experimental pneumocystosis, singly and in combination: analysis of drug interactions and efficacies. | 1997 | Antimicrob. Agents Chemother. | pmid:9021174 |
| Banerjee DK et al. | Experimental evaluation of possible new short-term drug regimens for treatment of multibacillary leprosy. | 1997 | Antimicrob. Agents Chemother. | pmid:9021187 |
| Paar D et al. | Life-threatening interaction between clarithromycin and disopyramide. | 1997 | Lancet | pmid:9024381 |
| Tonai A et al. | [Clarithromycin suppression of DNA synthesis by rat nasal mucosal cells enhanced by endotoxin instillation]. | 1997 | Jpn J Antibiot | pmid:9678983 |
| Szántó D et al. | [Could Helicobacter pylori cause reactive arthro-osteitis?]. | 1997 | Orv Hetil | pmid:9340585 |
| Rodrigues AD and Wong SL | Application of human liver microsomes in metabolism-based drug-drug interactions: in vitro-in vivo correlations and the Abbott Laboratories experience. | 1997 | Adv. Pharmacol. | pmid:9342173 |
| Yasui N et al. | Carbamazepine toxicity induced by clarithromycin coadministration in psychiatric patients. | 1997 | Int Clin Psychopharmacol | pmid:9347384 |
| May T et al. | Comparison of combination therapy regimens for treatment of human immunodeficiency virus-infected patients with disseminated bacteremia due to Mycobacterium avium. ANRS Trial 033 Curavium Group. Agence Nationale de Recherche sur le Sida. | 1997 | Clin. Infect. Dis. | pmid:9314450 |
| Dohil R et al. | Effective 2-wk therapy for Helicobacter pylori disease in children. | 1997 | Am. J. Gastroenterol. | pmid:9040199 |
| Wright DH | Regression of mucosa-associated lymphoid-tissue lymphoma after eradication of Helicobacter pylori. | 1997 | Lancet | pmid:9314895 |
| Lerang F et al. | Highly effective twice-daily triple therapies for Helicobacter pylori infection and peptic ulcer disease: does in vitro metronidazole resistance have any clinical relevance? | 1997 | Am. J. Gastroenterol. | pmid:9040200 |
| Picardeau M et al. | Use of different molecular typing techniques for bacteriological follow-up in a clinical trial with AIDS patients with Mycobacterium avium bacteremia. | 1997 | J. Clin. Microbiol. | pmid:9316897 |
| Chey WD et al. | Bismuth subsalicylate instead of metronidazole with lansoprazole and clarithromycin for Helicobacter pylori infection: a randomized trial. | 1997 | Am. J. Gastroenterol. | pmid:9317068 |
| Brown BA et al. | Clarithromycin-associated digoxin toxicity in the elderly. | 1997 | Clin. Infect. Dis. | pmid:8994761 |
| de'Clari F | Ciprofloxacin was the culprit--not itraconazole. | 1997 | Clin. Infect. Dis. | pmid:8994764 |
| Raasveld MH et al. | Cat-scratch disease mimicking pancreatic malignancy: case report. | 1997 | Clin. Infect. Dis. | pmid:8994767 |
| Pipkin GA et al. | Clarithromycin dual therapy regimens for eradication of Helicobacter pylori: a review. | 1997 | Helicobacter | pmid:9421117 |
| Tompkins DS et al. | Failed treatment of Helicobacter pylori infection associated with resistance to clarithromycin. | 1997 | Helicobacter | pmid:9421121 |
| Taylor JL et al. | Pharmacoeconomic comparison of treatments for the eradication of Helicobacter pylori. | 1997 | Arch. Intern. Med. | pmid:8996045 |
| Hultén K et al. | Combination treatment with ranitidine is highly efficient against Helicobacter pylori despite negative impact of macrolide resistance. | 1997 | Helicobacter | pmid:9421122 |
| Drugs for treatment of peptic ulcers. | 1997 | Med Lett Drugs Ther | pmid:8996458 | |
| O'Connor HJ et al. | One week triple therapy for Helicobacter pylori: does high-dose clarithromycin confer additional benefit? | 1997 | Helicobacter | pmid:9421124 |
| Dautzenberg B | Rationale for the prevention of disseminated Mycobacterium avium-intracellulare complex disease. | 1997 | Drugs | pmid:9358194 |
| Kokubo Y et al. | [Effects of clarithromycin on experimental pulmonary metastasis]. | 1997 | Jpn J Antibiot | pmid:9597436 |
| Cohn DL | Prevention strategies for Mycobacterium avium-intracellulare complex (MAC) infection. A review of recent studies in patients with AIDS. | 1997 | Drugs | pmid:9358195 |
| Sakamoto M et al. | [Efficacy of clarithromycin on cancer cachexia in patients with primary non-small cell lung cancer]. | 1997 | Jpn J Antibiot | pmid:9597437 |
| Marone P et al. | Rapid drug susceptibility of Mycobacterium avium complex using a fluorescence quenching method. | 1997 | J Chemother | pmid:9269603 |
| Teramoto S et al. | [Fluctuation in the cytokine m-RNA content in primary non-small cell lung cancer caused by clarithromycin (CAM) administration]. | 1997 | Jpn J Antibiot | pmid:9597438 |
| Mikasa K et al. | [Effect of clarithromycin on prolonging the life expectancy of patients with primary lung cancer]. | 1997 | Jpn J Antibiot | pmid:9597439 |
| Takeda H et al. | [Macrolide antibiotic actions on bacteria and cultured airway cells]. | 1997 | Jpn J Antibiot | pmid:9597448 |
| Mita Y et al. | [Vitamin D3 induction of differentiation of HL-60 cells to monocyte- like cells and their aggregation--a dynamic culture method and clarithromycin]. | 1997 | Jpn J Antibiot | pmid:9597462 |
| Yanagihara K et al. | [Analysis of chronic respiratory tract infection by using an intubation model--evaluation based on fluctuations in cytokine content]. | 1997 | Jpn J Antibiot | pmid:9597463 |
| Konishi M et al. | [Log-term administration of clarithromycin as a possible adjuvant therapy of HIV infections]. | 1997 | Jpn J Antibiot | pmid:9597467 |
| Reisner BS et al. | Electron microscopic analysis of Mycobacterium avium complex isolates exposed to ciprofloxacin, rifabutin, ethambutol and clarithromycin. | 1997 | Int. J. Tuberc. Lung Dis. | pmid:9432376 |
| Lerang F et al. | Highly effective second-line anti-Helicobacter pylori therapy in patients with previously failed metronidazole-based therapy. | 1997 | Scand. J. Gastroenterol. | pmid:9438318 |
| Akiyama H et al. | Biofilm formation of Staphylococcus aureus strains isolated from impetigo and furuncle: role of fibrinogen and fibrin. | 1997 | J. Dermatol. Sci. | pmid:9438901 |
| Bazzoli F and Pozzato P | Therapy of H. pylori infection. | 1997 | J. Physiol. Pharmacol. | pmid:9440054 |
| Dixon JS et al. | Ranitidine bismuth citrate plus clarithromycin for the eradication of H. pylori. | 1997 | J. Physiol. Pharmacol. | pmid:9440055 |
| Yatsunami J et al. | Clarithromycin is a potent inhibitor of tumor-induced angiogenesis. | 1997 | Res Exp Med (Berl) | pmid:9440137 |
| Boixeda de Miquel D | [Efficacy of the triple therapy in the eradication of H. pylori in peptic ulcer]. | 1997 | Rev Esp Enferm Dig | pmid:9494374 |
| Konishi T and Nakao M | Antibiotic treatment in mice infected with Japanese Borrelia garinii: efficacy of ceftriaxone for eradicating the infection induced by Ixodes persulcatus tick bites. | 1997 | Microbiol. Immunol. | pmid:9087959 |
| Pérez Mota A et al. | Helicobacter pylori, efficacy of the new triple therapy in six and twelve-day schedules. | 1997 | Rev Esp Enferm Dig | pmid:9494375 |
| Payen MC et al. | [Manifestations, diagnosis and treatment of non-tuberculous mycobacterial infections in patients with HIV infection]. | 1997 | Rev Mal Respir | pmid:9496599 |
| Weiss I et al. | Serotyping and susceptibility to macrolides and other antimicrobial drugs of Streptococcus pyogenes isolated from patients with invasive diseases in southern Israel. | 1997 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:9063669 |
| Klein JO | History of macrolide use in pediatrics. | 1997 | Pediatr. Infect. Dis. J. | pmid:9109154 |
| McCracken GH | Microbiologic activity of the newer macrolide antibiotics. | 1997 | Pediatr. Infect. Dis. J. | pmid:9109155 |
| Tarlow MJ | Macrolides in the management of streptococcal pharyngitis/tonsillitis. | 1997 | Pediatr. Infect. Dis. J. | pmid:9109157 |
| Harris A | H. pylori eradication by LAC. | 1997 | Aliment. Pharmacol. Ther. | pmid:9354216 |
| Jablonowski H et al. | Ancillary benefits of Mycobacterium avium-intracellulare complex prophylaxis with clarithromycin in HIV-infected patients. | 1997 | Drugs | pmid:9358196 |
| Grosset J and Ji B | Prevention of the selection of clarithromycin-resistant Mycobacterium avium-intracellulare complex. | 1997 | Drugs | pmid:9358197 |
| Dubé MP et al. | A randomized evaluation of ethambutol for prevention of relapse and drug resistance during treatment of Mycobacterium avium complex bacteremia with clarithromycin-based combination therapy. California Collaborative Treatment Group. | 1997 | J. Infect. Dis. | pmid:9359722 |
| Uemura N et al. | Effect of Helicobacter pylori eradication on subsequent development of cancer after endoscopic resection of early gastric cancer. | 1997 | Cancer Epidemiol. Biomarkers Prev. | pmid:9264278 |
| Misiewicz JJ | Management of Helicobacter pylori-related disorders. | 1997 | Eur J Gastroenterol Hepatol | pmid:9160212 |
| Mor N and Esfandiari A | Synergistic activities of clarithromycin and pyrazinamide against Mycobacterium tuberculosis in human macrophages. | 1997 | Antimicrob. Agents Chemother. | pmid:9303411 |
| Savarino V et al. | A new 1-week therapy for Helicobacter pylori eradication: ranitidine bismuth citrate plus two antibiotics. | 1997 | Aliment. Pharmacol. Ther. | pmid:9305478 |
| Williams MP et al. | Seven-day treatment for Helicobacter pylori infection: ranitidine bismuth citrate plus clarithromycin and tetracycline hydrochloride. | 1997 | Aliment. Pharmacol. Ther. | pmid:9305479 |
| Sánchez-Nuñez ML et al. | Clarithromycin in the treatment of cyclosporin-associated gingival hyperplasia. | 1997 | Nephrol. Dial. Transplant. | pmid:9306384 |
| Finkenbine R and Gill HS | Case of mania due to prednisone-clarithromycin interaction. | 1997 | Can J Psychiatry | pmid:9307841 |
| Gisbert JP et al. | Unhealed duodenal ulcers despite Helicobacter pylori eradication. | 1997 | Scand. J. Gastroenterol. | pmid:9246702 |
| Fuursted K | Evaluation of the post-antibiotic effect of six anti-mycobacterial agents against Mycobacterium avium by the Bactec radiometric method. | 1997 | J. Antimicrob. Chemother. | pmid:9249202 |
| Polis MA et al. | Clarithromycin lowers plasma zidovudine levels in persons with human immunodeficiency virus infection. | 1997 | Antimicrob. Agents Chemother. | pmid:9257746 |
| Shibata K et al. | Bactericidal effect of ecabet sodium on clarithromycin- and metronidazole-resistant clinical isolates of Helicobacter pylori. | 1997 | Jpn J Antibiot | pmid:9258741 |
| Sato K et al. | [Anti-Mycobacterium avium complex activities of KRM-1648, clarithromycin and levofloxacin in 7HSF medium at peak or average blood concentrations after their oral administration of clinical dosages]. | 1997 | Kekkaku | pmid:9259129 |
| OÄŸuz O et al. | Conjunctival involvement in familial chronic benign pemphigus (Hailey-Hailey disease). | 1997 | Int. J. Dermatol. | pmid:9169328 |
| Alfandari S et al. | Isolated cutaneous Mycobacterium avium complex infection in AIDS. | 1997 | Int. J. Dermatol. | pmid:9169332 |
| Tillenburg B et al. | [Helicobacter pylori: pretherapeutic resistance status in Germany (Ruhr area)]. | 1997 | Z Gastroenterol | pmid:9173687 |
| Veldhuyzen van Zanten SJ et al. | Helicobacter pylori: new developments and treatments. | 1997 | CMAJ | pmid:9176424 |
| Kundu S et al. | Clarithromycin-induced ventricular tachycardia. | 1997 | Ann Emerg Med | pmid:9326871 |
| Kato A | [Effect of erythromycin and clarithromycin on ion transport across dissected canine tracheal epithelium]. | 1997 | Nippon Jibiinkoka Gakkai Kaiho | pmid:9103848 |
| Fietta A et al. | Requirements for intracellular accumulation and release of clarithromycin and azithromycin by human phagocytes. | 1997 | J Chemother | pmid:9106014 |
| Matsukura N | [Two step therapy for education of Helicobacter pylori]. | 1997 | Nihon Shokakibyo Gakkai Zasshi | pmid:9284449 |
| Tan WC et al. | Helicobacter pylori eradication--comparison of three drug regimens and symptomatic assessment in duodenitis and antral gastritis. | 1997 | Int. J. Clin. Pract. | pmid:9287260 |
| Kobler E et al. | [Effectiveness of short-term triple therapy for healing Helicobacter pylori infection in ulcer disease]. | 1997 | Schweiz Med Wochenschr Suppl | pmid:9289833 |