| MeSH term | MeSH ID | Detail |
|---|---|---|
| Cutaneous Fistula | D017577 | 1 associated lipids |
| Kleine-Levin Syndrome | D017593 | 1 associated lipids |
| Encephalomyelitis, Acute Disseminated | D004673 | 1 associated lipids |
| Empyema, Tuberculous | D004654 | 1 associated lipids |
| Tuberculosis, Ocular | D014392 | 1 associated lipids |
| Immune Reconstitution Inflammatory Syndrome | D054019 | 1 associated lipids |
| Serositis | D012700 | 1 associated lipids |
| Euthyroid Sick Syndromes | D005067 | 1 associated lipids |
| Glossitis, Benign Migratory | D005929 | 1 associated lipids |
| Parotid Diseases | D010305 | 1 associated lipids |
clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with clarithromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (5)
- Drug Metab. Dispos. (1)
- FEMS Immunol. Med. Microbiol. (1)
- Others (5)
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Bowers JR et al. | Dominance of multidrug resistant CC271 clones in macrolide-resistant streptococcus pneumoniae in Arizona. | 2012 | BMC Microbiol. | pmid:22251616 |
| Miftahussurur M et al. | Emerging Helicobacter pylori levofloxacin resistance and novel genetic mutation in Nepal. | 2016 | BMC Microbiol. | pmid:27809767 |
| Liu Z et al. | Prevalence of A2143G mutation of H. pylori-23S rRNA in Chinese subjects with and without clarithromycin use history. | 2008 | BMC Microbiol. | pmid:18507832 |
| Ahmad S et al. | Azithromycin effectiveness against intracellular infections of Francisella. | 2010 | BMC Microbiol. | pmid:20416090 |
| De Vecchi E et al. | In vitro activity of telithromycin against Haemophilus influenzae at epithelial lining fluid concentrations. | 2008 | BMC Microbiol. | pmid:18230154 |
| Cerqueira L et al. | PNA-FISH as a new diagnostic method for the determination of clarithromycin resistance of Helicobacter pylori. | 2011 | BMC Microbiol. | pmid:21569555 |
| Rodrigues L et al. | Ethidium bromide transport across Mycobacterium smegmatis cell-wall: correlation with antibiotic resistance. | 2011 | BMC Microbiol. | pmid:21332993 |
| Parra D et al. | In vitro efficacy of daptomycin and teicoplanin combined with ethanol, clarithromycin or gentamicin as catheter lock solutions. | 2015 | BMC Microbiol. | pmid:26518881 |
| Humphrey B et al. | Fitness of Escherichia coli strains carrying expressed and partially silent IncN and IncP1 plasmids. | 2012 | BMC Microbiol. | pmid:22475035 |
| DiCicco M et al. | In vitro synergism of fosfomycin and clarithromycin antimicrobials against methicillin-resistant Staphylococcus pseudintermedius. | 2014 | BMC Microbiol. | pmid:24886369 |
| Chan Carusone S et al. | Lack of association between vascular dementia and Chlamydia pneumoniae infection: a case-control study. | 2004 | BMC Neurol | pmid:15476562 |
| Baier RJ et al. | Failure of erythromycin to eliminate airway colonization with ureaplasma urealyticum in very low birth weight infants. | 2003 | BMC Pediatr | pmid:12956892 |
| Yoshida N et al. | A cross-sectional investigation of the quality of selected medicines in Cambodia in 2010. | 2014 | BMC Pharmacol Toxicol | pmid:24593851 |
| Iwayama K et al. | Long-term treatment of clarithromycin at a low concentration improves hydrogen peroxide-induced oxidant/antioxidant imbalance in human small airway epithelial cells by increasing Nrf2 mRNA expression. | 2017 | BMC Pharmacol Toxicol | pmid:28235416 |
| Sarkar M et al. | Pregnancy outcome following gestational exposure to azithromycin. | 2006 | BMC Pregnancy Childbirth | pmid:16734900 |
| Witt MN et al. | Occurrence of HSV-1-induced pneumonitis in patients under standard immunosuppressive therapy for rheumatic, vasculitic, and connective tissue disease. | 2009 | BMC Pulm Med | pmid:19450259 |
| Ernst P et al. | Risk of herpes zoster in patients prescribed inhaled corticosteroids: a cohort study. | 2011 | BMC Pulm Med | pmid:22177425 |
| Okano Y et al. | Miliary pulmonary nodules due to Mycobacterium xenopi in a steroid-induced immunocompromised patient successfully treated with chemotherapy: a case report. | 2016 | BMC Pulm Med | pmid:27287608 |
| Davis KK et al. | Aerosolized amikacin for treatment of pulmonary Mycobacterium avium infections: an observational case series. | 2007 | BMC Pulm Med | pmid:17319962 |
| Gross CA et al. | beta2-agonists promote host defense against bacterial infection in primary human bronchial epithelial cells. | 2010 | BMC Pulm Med | pmid:20470412 |
| Lee JS et al. | Implication of species change of Nontuberculous Mycobacteria during or after treatment. | 2017 | BMC Pulm Med | pmid:29262802 |
| Namkoong H et al. | Successful resumption of tocilizumab for rheumatoid arthritis after resection of a pulmonary Mycobacterium avium complex lesion: a case report. | 2015 | BMC Pulm Med | pmid:26496968 |
| Somprasong N et al. | Methods for genetic manipulation of Burkholderia gladioli pathovar cocovenenans. | 2010 | BMC Res Notes | pmid:21080961 |
| Daniels NA et al. | Antibiotic and anti-inflammatory use and the risk of prostate cancer. | 2009 | BMC Res Notes | pmid:19374749 |
| Kumarihamy KW et al. | A rare complication of pulmonary tuberculosis: a case report. | 2015 | BMC Res Notes | pmid:25888831 |
| Mortensen EM et al. | Impact of prior outpatient antibiotic use on mortality for community acquired pneumonia: a retrospective cohort study. | 2008 | BMC Res Notes | pmid:19046440 |
| Abukaraky AE et al. | Antibiotics prescribing practices in oral implantology among jordanian dentists. A cross sectional, observational study. | 2011 | BMC Res Notes | pmid:21798040 |
| Sakinc T et al. | Influence of a 23S ribosomal RNA mutation in Helicobacter pylori strains on the in vitro synergistic effect of clarithromycin and amoxicillin. | 2012 | BMC Res Notes | pmid:23110798 |
| Kontarakis N et al. | Antibiotic prescriptions in primary health care in a rural population in Crete, Greece. | 2011 | BMC Res Notes | pmid:21320356 |
| Brinkman JM et al. | Non-operative treatment for perforated gastro-duodenal peptic ulcer in Duchenne muscular dystrophy: a case report. | 2004 | BMC Surg | pmid:14713321 |
| Dicicco M et al. | Efficacy of clarithromycin on biofilm formation of methicillin-resistant Staphylococcus pseudintermedius. | 2012 | BMC Vet. Res. | pmid:23171620 |
| Braden B | The best and worst treatments for Helicobacter pylori. | 2015 | BMJ | pmid:26290321 |
| Li BZ et al. | Comparative effectiveness and tolerance of treatments for Helicobacter pylori: systematic review and network meta-analysis. | 2015 | BMJ | pmid:26290044 |
| Cals JW et al. | Effect of point of care testing for C reactive protein and training in communication skills on antibiotic use in lower respiratory tract infections: cluster randomised trial. | 2009 | BMJ | pmid:19416992 |
| Talley NJ et al. | Eradication of Helicobacter pylori in functional dyspepsia: randomised double blind placebo controlled trial with 12 months' follow up. The Optimal Regimen Cures Helicobacter Induced Dyspepsia (ORCHID) Study Group. | 1999 | BMJ | pmid:10092259 |
| Tornese G et al. | Erythromycin in whooping cough. | 2009 | BMJ | pmid:19564191 |
| Bisgaard H et al. | Association of bacteria and viruses with wheezy episodes in young children: prospective birth cohort study. | 2010 | BMJ | pmid:20921080 |
| Sturkenboom MC et al. | Drug use in children: cohort study in three European countries. | 2008 | BMJ | pmid:19029175 |
| Jespersen CM et al. | Randomised placebo controlled multicentre trial to assess short term clarithromycin for patients with stable coronary heart disease: CLARICOR trial. | 2006 | BMJ | pmid:16339220 |
| Svanström H et al. | Use of clarithromycin and roxithromycin and risk of cardiac death: cohort study. | 2014 | BMJ | pmid:25139799 |
| Lane JA et al. | Impact of Helicobacter pylori eradication on dyspepsia, health resource use, and quality of life in the Bristol helicobacter project: randomised controlled trial. | 2006 | BMJ | pmid:16428249 |
| Terzano C and Petroianni A | Clarithromycin and pulmonary infiltration with eosinophilia. | 2003 | BMJ | pmid:12816827 |
| Mayor S | Short term increase in neuropsychiatric events is seen with H pylori treatment containing clarithromycin. | 2016 | BMJ | pmid:27143325 |
| Gibbins NE et al. | Time to reconsider guidelines on clarithromycin in chronic rhinosinusitis? | 2013 | BMJ | pmid:23635541 |
| Hermon-Taylor J et al. | Mycobacterium paratuberculosis cervical lymphadenitis, followed five years later by terminal ileitis similar to Crohn's disease. | 1998 | BMJ | pmid:9492675 |
| Wong IC | Author's reply to Blake. | 2016 | BMJ | pmid:26957514 |
| Iyer G and Alexander GC | Editorialists' reply to Blake. | 2016 | BMJ | pmid:26957321 |
| Blake Z | Study provides insufficient evidence of a link between clarithromycin and myocardial infarction. | 2016 | BMJ | pmid:26955978 |
| Chiba N et al. | Treating Helicobacter pylori infection in primary care patients with uninvestigated dyspepsia: the Canadian adult dyspepsia empiric treatment-Helicobacter pylori positive (CADET-Hp) randomised controlled trial. | 2002 | BMJ | pmid:11976244 |
| Iyer G and Alexander GC | Cardiovascular risks associated with clarithromycin. | 2016 | BMJ | pmid:26769796 |
| Wong AY et al. | Cardiovascular outcomes associated with use of clarithromycin: population based study. | 2016 | BMJ | pmid:26768836 |
| Schembri S et al. | Cardiovascular events after clarithromycin use in lower respiratory tract infections: analysis of two prospective cohort studies. | 2013 | BMJ | pmid:23525864 |
| Bharani A and Kumar H | Drug points: Diabetes inspidus induced by ofloxacin. | 2001 | BMJ | pmid:11546701 |
| Butler CC et al. | Effectiveness of multifaceted educational programme to reduce antibiotic dispensing in primary care: practice based randomised controlled trial. | 2012 | BMJ | pmid:22302780 |
| Gbinigie II and Lasserson D | Clarithromycin-induced akathisia: a class effect of macrolides? | 2016 | BMJ Case Rep | pmid:27927708 |
| Lally L and Mannion L | The potential for antimicrobials to adversely affect mental state. | 2013 | BMJ Case Rep | pmid:23833088 |
| Hill FJ et al. | From a fish tank injury to hospital haemodialysis: the serious consequences of drug interactions. | 2015 | BMJ Case Rep | pmid:26106178 |
| Phaw NA and Tsai HH | Eosinophilic gastroenteritis: a challenge to diagnose and treat. | 2016 | BMJ Case Rep | pmid:27613263 |
| Smyth A et al. | Atypical cause of prolonged myelosuppression. | 2009 | BMJ Case Rep | pmid:22162739 |
| Guzman Vinasco L et al. | Acute suppurative parotitis caused by Streptococcus pneumoniae in an HIV-infected man. | 2015 | BMJ Case Rep | pmid:25733094 |
| Santos RP et al. | induced rash and mucositis: a recently described entity. | 2017 | BMJ Case Rep | pmid:28830900 |
| Tso S et al. | Clarithromycin as a steroid sparing agent for the management of infantile bullous pemphigoid. | 2018 | BMJ Case Rep | pmid:29374651 |
| Laidler N | Cutaneous infection with paucibacillary treated successfully with a modified antituberculous drug regimen. | 2017 | BMJ Case Rep | pmid:29275384 |
| Kant S et al. | Extra-pulmonary primary multidrug-resistant tubercular lymphadenitis in an HIV negative patient. | 2012 | BMJ Case Rep | pmid:22605844 |
| Vaz AM et al. | Capsule endoscopy in the diagnosis of disseminated complex infection. | 2017 | BMJ Case Rep | pmid:29167222 |
| Brereton AS and El Teraifi H | Mycobacterium malmoense: dissemination causes a popliteal aneurysm in a 74-year-old man. | 2012 | BMJ Case Rep | pmid:22602841 |
| Kakked GA et al. | Pneumobilia with gastric outlet obstruction. | 2015 | BMJ Case Rep | pmid:26552878 |
| Glatz M and Muellegger RR | Drug-associated aquagenic wrinkling of the palms in an atopic male patient. | 2014 | BMJ Case Rep | pmid:24903725 |
| Blair PW et al. | DRESS syndrome presenting after initiation of mycobacterium avium complex osteomyelitis treatment. | 2015 | BMJ Case Rep | pmid:26438676 |
| Chahil N et al. | Novel approach to treatment of rectal mucosa-associated lymphoid tissue lymphoma. | 2011 | BMJ Case Rep | pmid:22715275 |
| Gandhi V et al. | An unusual surgical site infection in a liver transplant recipient. | 2010 | BMJ Case Rep | pmid:22778369 |
| Cronnolly B and Pegrum H | Fentanyl-clarithromycin interaction. | 2012 | BMJ Case Rep | pmid:22778456 |
| Miyauchi R et al. | Clarithromycin-induced haemorrhagic colitis. | 2013 | BMJ Case Rep | pmid:23964038 |
| Olesen JS et al. | Mycobacterium chelonae hand infection after steroid injection in a patient with rheumatoid arthritis receiving long-term linezolid therapy. | 2017 | BMJ Case Rep | pmid:28137898 |
| Takeuchi S et al. | Hypotension induced by the concomitant use of a calcium-channel blocker and clarithromycin. | 2017 | BMJ Case Rep | pmid:28069789 |
| Horner P | Chlamydia (uncomplicated, genital). | 2010 | BMJ Clin Evid | pmid:21718568 |
| Horner P | Chlamydia (uncomplicated, genital). | 2008 | BMJ Clin Evid | pmid:19450291 |
| Aberg J and Powderly W | HIV: primary and secondary prophylaxis for opportunistic infections. | 2010 | BMJ Clin Evid | pmid:21418688 |
| Nathwani D et al. | MRSA: treating people with infection. | 2010 | BMJ Clin Evid | pmid:21418679 |
| Hiroi S et al. | Impact of health insurance coverage for gastritis on the trends in eradication therapy in Japan: retrospective observational study and simulation study based on real-world data. | 2017 | BMJ Open | pmid:28760790 |
| Berni E et al. | Risk of cardiovascular events, arrhythmia and all-cause mortality associated with clarithromycin versus alternative antibiotics prescribed for respiratory tract infections: a retrospective cohort study. | 2017 | BMJ Open | pmid:28115334 |
| Avery RK et al. | The efficacy of prophylactic outpatient antibiotics for the prevention of neutropenic fever associated with high-dose etoposide (VP-16) for stem cell mobilization. | 2002 | Bone Marrow Transplant. | pmid:12209353 |
| Okano A et al. | Subcutaneous infection with Mycobacterium fortuitum after allogeneic bone marrow transplantation. | 2001 | Bone Marrow Transplant. | pmid:11704796 |
| Kefeli A et al. | Comparison of three different regimens against Helicobacter pylori as a first-line treatment: A randomized clinical trial. | 2016 | Bosn J Basic Med Sci | pmid:26773183 |
| Basyigit S et al. | The impact of bismuth addition to sequential treatment on Helicobacter pylori eradication: A pilot study. | 2015 | Bosn J Basic Med Sci | pmid:26614852 |
| Stepney R et al. | Case report: Improved gum health. | 2015 | Br Dent J | pmid:26657423 |
| Lilja JJ et al. | Effects of clarithromycin and grapefruit juice on the pharmacokinetics of glibenclamide. | 2007 | Br J Clin Pharmacol | pmid:17223855 |
| Kim SY et al. | Effectiveness of three times daily lansoprazole/amoxicillin dual therapy for Helicobacter pylori infection in Korea. | 2012 | Br J Clin Pharmacol | pmid:21689141 |
| Quinney SK et al. | Interaction between midazolam and clarithromycin in the elderly. | 2008 | Br J Clin Pharmacol | pmid:17635500 |
| Spicer ST et al. | The mechanism of cyclosporine toxicity induced by clarithromycin. | 1997 | Br J Clin Pharmacol | pmid:9131953 |
| Johnston A et al. | Effectiveness, safety and cost of drug substitution in hypertension. | 2010 | Br J Clin Pharmacol | pmid:20716230 |
| Holmes NE et al. | Report of oral clarithromycin desensitization. | 2008 | Br J Clin Pharmacol | pmid:18460032 |
| Yang JC et al. | Pharmacokinetic- pharmacodynamic analysis of the role of CYP2C19 genotypes in short-term rabeprazole-based triple therapy against Helicobacter pylori. | 2009 | Br J Clin Pharmacol | pmid:19552744 |
| Raschi E et al. | Exposure to antibacterial agents with QT liability in 14 European countries: trends over an 8-year period. | 2009 | Br J Clin Pharmacol | pmid:19076158 |
| Al-Eidan FA et al. | Management of Helicobacter pylori eradication--the influence of structured counselling and follow-up. | 2002 | Br J Clin Pharmacol | pmid:11851640 |
| Root AA et al. | Evaluation of the risk of cardiovascular events with clarithromycin using both propensity score and self-controlled study designs. | 2016 | Br J Clin Pharmacol | pmid:27090996 |
| Delavenne X et al. | A semi-mechanistic absorption model to evaluate drug-drug interaction with dabigatran: application with clarithromycin. | 2013 | Br J Clin Pharmacol | pmid:23210726 |
| Mueck W et al. | Co-administration of rivaroxaban with drugs that share its elimination pathways: pharmacokinetic effects in healthy subjects. | 2013 | Br J Clin Pharmacol | pmid:23305158 |
| Santucci R et al. | The onset of acute oxcarbazepine toxicity related to prescription of clarithromycin in a child with refractory epilepsy. | 2010 | Br J Clin Pharmacol | pmid:20233205 |
| Saito M et al. | Effects of clarithromycin on lansoprazole pharmacokinetics between CYP2C19 genotypes. | 2005 | Br J Clin Pharmacol | pmid:15752376 |